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Aliases for FAM25E Gene

Aliases for FAM25E Gene

  • Family With Sequence Similarity 25 Member E 2 3 5
  • Family With Sequence Similarity 25, Member E 2
  • FAM25D FAM25E 4

External Ids for FAM25E Gene

Previous GeneCards Identifiers for FAM25E Gene

  • GC10U900497
  • GC10M050888
  • GC10M046310

Summaries for FAM25E Gene

GeneCards Summary for FAM25E Gene

FAM25E (Family With Sequence Similarity 25 Member E) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM25E Gene

Genomics for FAM25E Gene

Regulatory Elements for FAM25E Gene

Enhancers for FAM25E Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F046565 1.3 Ensembl ENCODE 16.2 -748.6 -748584 0.7 PKNOX1 ZNF133 ARID4B SIN3A ZNF48 ZNF2 YY1 GATA2 ZNF302 ZNF143 FAM25E AGAP4 GPRIN2 PIR34546
GH10F045821 0.2 Ensembl 0.8 -4.7 -4746 0.7 FAM25E PIR47123
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM25E on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM25E Gene

45,815,428 bp from pter
45,817,324 bp from pter
1,897 bases
Minus strand

Genomic View for FAM25E Gene

Genes around FAM25E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM25E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM25E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25E Gene

Proteins for FAM25E Gene

  • Protein details for FAM25E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM25D/E
    Protein Accession:

    Protein attributes for FAM25E Gene

    175 amino acids
    Molecular mass:
    18345 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM25E Gene

Post-translational modifications for FAM25E Gene

No Post-translational modifications

Other Protein References for FAM25E Gene

REFSEQ proteins:

No data available for DME Specific Peptides for FAM25E Gene

Domains & Families for FAM25E Gene

Protein Domains for FAM25E Gene


Suggested Antigen Peptide Sequences for FAM25E Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM25 family.
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25E: view

No data available for Gene Families for FAM25E Gene

Function for FAM25E Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM25E Gene

Localization for FAM25E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM25E Gene

Pathways & Interactions for FAM25E Gene

SuperPathways for FAM25E Gene

No Data Available

Interacting Proteins for FAM25E Gene

Gene Ontology (GO) - Biological Process for FAM25E Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM25E Gene

Transcripts for FAM25E Gene

mRNA/cDNA for FAM25E Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25E Gene

No ASD Table

Relevant External Links for FAM25E Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM25E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM25E Gene

Protein differential expression in normal tissues from HIPED for FAM25E Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM25E Gene

Protein tissue co-expression partners for FAM25E Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM25E Gene:

genes like me logo Genes that share expression patterns with FAM25E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM25E Gene

Orthologs for FAM25E Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM25E Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 70 (a)
(Mus musculus)
Mammalia Fam25c 35
  • 65 (a)
(Canis familiaris)
Mammalia -- 35
  • 58 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 49 (a)
Species where no ortholog for FAM25E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM25E Gene

Gene Tree for FAM25E (if available)
Gene Tree for FAM25E (if available)

Paralogs for FAM25E Gene

(4) SIMAP similar genes for FAM25E Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM25E: view

No data available for Paralogs for FAM25E Gene

Variants for FAM25E Gene

Sequence variations from dbSNP and Humsavar for FAM25E Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs2242009 -- 45,817,047(-) CTATG(C/T)TCATC intron-variant
rs34652217 -- 45,815,348(+) AAATA(C/T)GTAAA downstream-variant-500B
rs35406053 -- 45,815,378(+) AATAC(-/T)TTTGC utr-variant-3-prime
rs35709399 -- 45,816,597(+) CCCAG(A/C)TGATT intron-variant
rs368313186 -- 45,818,713(+) AGAGA(C/T)GAGAA utr-variant-5-prime

Relevant External Links for FAM25E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for FAM25E Gene

Disorders for FAM25E Gene

No disorders were found for FAM25E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for FAM25E Gene

Publications for FAM25E Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4 64

Products for FAM25E Gene

Sources for FAM25E Gene

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