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Aliases for FAM25C Gene

Aliases for FAM25C Gene

  • Family With Sequence Similarity 25 Member C 2 3 5
  • Family With Sequence Similarity 25, Member C 2
  • Protein FAM25C 3
  • Protein FAM25 3
  • BA164N7.4 3

External Ids for FAM25C Gene

Previous GeneCards Identifiers for FAM25C Gene

  • GC10U900496
  • GC10P047870
  • GC10M046601
  • GC10P088777
  • GC10M048879
  • GC10M049199

Summaries for FAM25C Gene

GeneCards Summary for FAM25C Gene

FAM25C (Family With Sequence Similarity 25 Member C) is a Protein Coding gene. An important paralog of this gene is FAM25G.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM25C Gene

Genomics for FAM25C Gene

Regulatory Elements for FAM25C Gene

Enhancers for FAM25C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G047994 0.4 Ensembl 0.4 +5.4 5391 0.4 CREB1 ANXA8 FAM25C
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM25C on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM25C Gene

Chromosome:
10
Start:
47,995,322 bp from pter
End:
47,999,791 bp from pter
Size:
4,470 bases
Orientation:
Minus strand

Genomic View for FAM25C Gene

Genes around FAM25C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM25C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM25C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25C Gene

Proteins for FAM25C Gene

  • Protein details for FAM25C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B3EWG5-FM25C_HUMAN
    Recommended name:
    Protein FAM25C
    Protein Accession:
    B3EWG5
    Secondary Accessions:
    • B2RV02
    • Q5VTM1

    Protein attributes for FAM25C Gene

    Size:
    89 amino acids
    Molecular mass:
    9320 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI12334.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for FAM25C Gene

Post-translational modifications for FAM25C Gene

No Post-translational modifications

Other Protein References for FAM25C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM25C Gene

Domains & Families for FAM25C Gene

Protein Domains for FAM25C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM25C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B3EWG5

UniProtKB/Swiss-Prot:

FM25C_HUMAN :
  • Belongs to the FAM25 family.
Family:
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25C: view

No data available for Gene Families for FAM25C Gene

Function for FAM25C Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM25C Gene

Localization for FAM25C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM25C gene
Compartment Confidence
cytosol 3
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM25C Gene

Pathways & Interactions for FAM25C Gene

SuperPathways for FAM25C Gene

No Data Available

Interacting Proteins for FAM25C Gene

Gene Ontology (GO) - Biological Process for FAM25C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM25C Gene

Transcripts for FAM25C Gene

mRNA/cDNA for FAM25C Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25C Gene

No ASD Table

Relevant External Links for FAM25C Gene

GeneLoc Exon Structure for
FAM25C
ECgene alternative splicing isoforms for
FAM25C

Expression for FAM25C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM25C Gene

mRNA differential expression in normal tissues according to GTEx for FAM25C Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x18.3), Skin - Not Sun Exposed (Suprapubic) (x15.7), and Esophagus - Mucosa (x6.8).

Protein differential expression in normal tissues from HIPED for FAM25C Gene

This gene is overexpressed in Saliva (68.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM25C Gene



Protein tissue co-expression partners for FAM25C Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of FAM25C Gene:

FAM25C

SOURCE GeneReport for Unigene cluster for FAM25C Gene:

Hs.645212
genes like me logo Genes that share expression patterns with FAM25C: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM25C Gene

Orthologs for FAM25C Gene

Evolution for FAM25C Gene

ENSEMBL:
Gene Tree for FAM25C (if available)
TreeFam:
Gene Tree for FAM25C (if available)

No data available for Orthologs for FAM25C Gene

Paralogs for FAM25C Gene

Paralogs for FAM25C Gene

(5) SIMAP similar genes for FAM25C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM25C: view

Variants for FAM25C Gene

Sequence variations from dbSNP and Humsavar for FAM25C Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs11100980 -- 47,998,213(+) CCTCA(C/G)GTTGG intron-variant
rs11101443 -- 47,994,914(+) AAAAA(A/T)AATAA downstream-variant-500B
rs113501518 -- 47,996,579(+) TTCCC(A/G)AAGGG intron-variant
rs113729642 -- 48,001,623(+) CATCT(A/G)CCTGC upstream-variant-2KB
rs11817664 -- 47,997,352(+) gatcc(A/G)ccctc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM25C Gene

Variant ID Type Subtype PubMed ID
dgv12e203 CNV loss 21179565
esv24863 CNV gain+loss 19812545
esv33214 CNV loss 17666407
nsv1042677 CNV loss 25217958
nsv1118173 CNV deletion 24896259
nsv469669 CNV gain+loss 16826518
nsv820931 CNV deletion 20802225
nsv947974 CNV duplication 23825009
nsv982760 CNV duplication 23825009

Variation tolerance for FAM25C Gene

Gene Damage Index Score: 0.22; 4.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM25C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM25C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM25C Gene

Disorders for FAM25C Gene

Relevant External Links for FAM25C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM25C

No disorders were found for FAM25C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM25C Gene

Publications for FAM25C Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for FAM25C Gene

Sources for FAM25C Gene

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