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Aliases for FAM25C Gene

Aliases for FAM25C Gene

  • Family With Sequence Similarity 25 Member C 2 3 5
  • Family With Sequence Similarity 25, Member C 2 3
  • Protein FAM25 3
  • BA164N7.4 3

External Ids for FAM25C Gene

Previous GeneCards Identifiers for FAM25C Gene

  • GC10U900496
  • GC10P047870
  • GC10M046601
  • GC10P088777
  • GC10M048879
  • GC10M049199

Summaries for FAM25C Gene

GeneCards Summary for FAM25C Gene

FAM25C (Family With Sequence Similarity 25 Member C) is a Protein Coding gene. An important paralog of this gene is FAM25A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM25C Gene

Genomics for FAM25C Gene

Regulatory Elements for FAM25C Gene

Enhancers for FAM25C Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM25C on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM25C Gene

Chromosome:
10
Start:
47,995,322 bp from pter
End:
47,999,791 bp from pter
Size:
4,470 bases
Orientation:
Minus strand

Genomic View for FAM25C Gene

Genes around FAM25C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM25C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM25C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25C Gene

Proteins for FAM25C Gene

  • Protein details for FAM25C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B3EWG5-FM25C_HUMAN
    Recommended name:
    Protein FAM25C
    Protein Accession:
    B3EWG5
    Secondary Accessions:
    • B2RV02
    • Q5VTM1

    Protein attributes for FAM25C Gene

    Size:
    89 amino acids
    Molecular mass:
    9320 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI12334.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for FAM25C Gene

Proteomics data for FAM25C Gene at MOPED

Post-translational modifications for FAM25C Gene

No Post-translational modifications

Other Protein References for FAM25C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM25C Gene

Domains & Families for FAM25C Gene

Protein Domains for FAM25C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM25C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

B3EWG5

UniProtKB/Swiss-Prot:

FM25C_HUMAN :
  • Belongs to the FAM25 family.
Family:
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25C: view

No data available for Gene Families for FAM25C Gene

Function for FAM25C Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM25C Gene

Localization for FAM25C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM25C Gene COMPARTMENTS Subcellular localization image for FAM25C gene
Compartment Confidence
cytosol 3
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM25C Gene

Pathways & Interactions for FAM25C Gene

SuperPathways for FAM25C Gene

No Data Available

Interacting Proteins for FAM25C Gene

Gene Ontology (GO) - Biological Process for FAM25C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM25C Gene

Drugs & Compounds for FAM25C Gene

No Compound Related Data Available

Transcripts for FAM25C Gene

mRNA/cDNA for FAM25C Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25C Gene

No ASD Table

Relevant External Links for FAM25C Gene

GeneLoc Exon Structure for
FAM25C
ECgene alternative splicing isoforms for
FAM25C

Expression for FAM25C Gene

mRNA expression in normal human tissues for FAM25C Gene

mRNA differential expression in normal tissues according to GTEx for FAM25C Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x18.3), Skin - Not Sun Exposed (Suprapubic) (x15.7), and Esophagus - Mucosa (x6.8).

Protein differential expression in normal tissues from HIPED for FAM25C Gene

This gene is overexpressed in Saliva (68.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM25C Gene



SOURCE GeneReport for Unigene cluster for FAM25C Gene Hs.645212

genes like me logo Genes that share expression patterns with FAM25C: view

Protein tissue co-expression partners for FAM25C Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM25C Gene

Orthologs for FAM25C Gene

Evolution for FAM25C Gene

ENSEMBL:
Gene Tree for FAM25C (if available)
TreeFam:
Gene Tree for FAM25C (if available)

No data available for Orthologs for FAM25C Gene

Paralogs for FAM25C Gene

Paralogs for FAM25C Gene

(5) SIMAP similar genes for FAM25C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM25C: view

Variants for FAM25C Gene

Sequence variations from dbSNP and Humsavar for FAM25C Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs3013917 -- 47,998,152(-) CTGGG(C/T)TTCAT intron-variant
rs3013918 -- 47,998,136(-) AGCTG(G/T)CAAGA intron-variant
rs3013919 -- 47,997,955(-) TGGCA(C/T)CCCAG intron-variant
rs3013923 -- 47,996,866(+) cgaca(C/G)tgtga intron-variant
rs3013926 -- 47,996,014(-) ATAAC(A/T)TCAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM25C Gene

Variant ID Type Subtype PubMed ID
dgv252e1 CNV Complex 17122850
esv2750898 CNV Loss 17911159
dgv254e1 CNV Complex 17122850
nsv516485 CNV Gain+Loss 19592680
nsv895114 CNV Gain 21882294
esv34875 CNV Gain 17911159
nsv510991 OTHER Complex 20534489
dgv256e1 CNV Complex 17122850
dgv257e1 CNV Complex 17122850
esv22204 CNV Gain+Loss 19812545
dgv258e1 CNV Complex 17122850
nsv8636 CNV Gain+Loss 18304495
nsv436102 CNV Deletion 17901297
nsv7203 OTHER Inversion 18451855
esv2736152 CNV Deletion 23290073
dgv656n71 CNV Gain 21882294
esv2736163 CNV Deletion 23290073
dgv259e1 CNV Complex 17122850
dgv260e1 CNV Complex 17122850
dgv657n71 CNV Gain 21882294
nsv895135 CNV Loss 21882294
dgv660n71 CNV Gain 21882294
dgv661n71 CNV Gain 21882294
dgv262e1 CNV Complex 17122850
dgv23e55 CNV Loss 17911159
dgv24e55 CNV Gain 17911159
nsv820817 CNV Duplication 20802225
nsv821667 CNV Gain 15273396
nsv470934 CNV Gain 18288195
dgv664n71 CNV Gain 21882294
nsv818758 CNV Gain 17921354
dgv665n71 CNV Gain 21882294
dgv264e1 CNV Complex 17122850
nsv831853 CNV Gain 17160897
dgv666n71 CNV Gain 21882294
nsv831854 CNV Gain 17160897
esv2663732 CNV Deletion 23128226
nsv467059 CNV Gain 19166990
esv21870 CNV Gain+Loss 19812545
nsv895340 CNV Gain 21882294
nsv831860 CNV Gain 17160897
dgv269e1 CNV Complex 17122850
dgv696n71 CNV Gain 21882294
nsv895342 CNV Loss 21882294
nsv895343 CNV Gain 21882294
dgv270e1 CNV Complex 17122850
dgv697n71 CNV Gain 21882294
dgv272e1 CNV Complex 17122850
nsv469669 CNV Complex 16826518
essv22497 CNV CNV 17122850
esv24863 CNV Gain+Loss 19812545
nsv820931 CNV Deletion 20802225
esv33214 CNV Loss 17666407

Variation tolerance for FAM25C Gene

Gene Damage Index Score: 0.22; 4.94% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM25C Gene

Disorders for FAM25C Gene

Relevant External Links for FAM25C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM25C

No disorders were found for FAM25C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM25C Gene

Publications for FAM25C Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM25C Gene

Sources for FAM25C Gene

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