FAM25B Gene
protein-coding GIFtS: 26
GCID: GC10M047177
|
|
family with sequence similarity 25, member B
| |
Aliases
for FAM25B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 25, Member B1 2 | | FAM25G2 | | BA144G6.81 | | Protein FAM252 | | FAM25A2 | | Protein FAM25B2 | | FAM25C2 | | |
Export aliases for FAM25B gene to outside databasesPrevious GC identifers: GC10U900495 GC10P047869 GC10M046602 GC10P088778 |
Summaries
for FAM25B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM25B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM25B gene promoter:
ER-alpha FAC1 AML1a p300 Olf-1 CUTL1 Ik-3 YY1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM25B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM25B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q11.22 Ensembl cytogenetic band: 10q11.22 HGNC cytogenetic band: 10q11.22FAM25B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M047177: view genomic region
(about GC identifiers)
Start:
|
47,177,204 bp from pter |
End:
|
47,181,688 bp from pter |
Size:
|
4,485 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM25B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FM25B_HUMAN, B3EWG4 (See
protein sequence)Recommended Name: Protein FAM25B Size: 89 amino acids; 9320 Da
Sequence caution: Sequence=CAI12205.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: B2RV02 Q5VTM1Explore the universe of human proteins at neXtProt for FAM25B: NX_B3EWG4
FAM25B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001131028.1
ENSEMBL proteins: ENSP00000413896
Human Recombinant Protein Products:
FAM25B Antibody Products:
Assay Products for FAM25B: |
Protein
Domains /
Families
for FAM25B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM25B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry B3EWG4ProtoNet protein and cluster: B3EWG4 UniProtKB/Swiss-Prot: FM25B_HUMAN, B3EWG4Similarity: Belongs to the FAM25 family |
Function
for FAM25B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM25B (NM_001137556) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM25B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM25B |
|
Pathways & Interactions
for FAM25B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM25B
|
Drugs & Compounds
for FAM25B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM25B
Search CenterWatch for drugs/clinical trials and news about FAM25B / FM25B
|
Transcripts
for FAM25B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM25B gene: NM_001137556.1 2 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000481177 ENST00000452267
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM25B (NM_001137556) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM25B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM25B |
GeneLoc Exon Structure
|
Expression
for FAM25B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM25B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM25B Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for FAM25B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM25B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM25B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM25B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM25B |
Orthologs
for FAM25B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for FAM25B (if available)
TreeFam Gene Tree for FAM25B (if available) |
Paralogs
for FAM25B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM25B gene
- FAM25G1 2 FAM25C1 2 FAM25A1 2 FAM25E2
5 SIMAP similar genes for FAM25B using alignment to 1 protein entry: FM25B_HUMAN:FAM25A FAM25C FAM25G FAM25D FAM25E
FAM25B for paralogs About GeneDecksing
|
Genomic Variants
for FAM25B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM25B (47177204 - 47181688 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 38 variations for FAM25B
15/38 CNVs (see all 38): 9150 3798 85254 8646 34572 48545 0307 3799 31728 9640 70999 48541 48535 48542 29593 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for FAM25B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM25B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed article for FAM25B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM25B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
|
External Searches for FAM25B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM25B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM25B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM25B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM25B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM25B gene:
Search GeneIP for patents involving FAM25B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM25B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM25B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM25B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM25B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM25B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM25B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM25B | | OriGene Custom Protein Services for FAM25B | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM25B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM25B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM25B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM25B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM25B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM25B |
| |
 |  |  |  | |
| | | | Search Tocris compounds for FAM25B |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | FAM25B Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for FAM25B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM25B |
|
|
|
|
