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Aliases for FAM25A Gene

Aliases for FAM25A Gene

  • Family With Sequence Similarity 25, Member A 2 3
  • Protein FAM25A 3
  • Protein FAM25 3
  • BA96C23.5 3

External Ids for FAM25A Gene

Previous GeneCards Identifiers for FAM25A Gene

  • GC10U900468
  • GC10P047872
  • GC10P088776
  • GC10P082633
  • GC10P088784
  • GC10P088787
  • GC10P088793
  • GC10P088798
  • GC10P088806

Summaries for FAM25A Gene

GeneCards Summary for FAM25A Gene

FAM25A (Family With Sequence Similarity 25, Member A) is a Protein Coding gene. An important paralog of this gene is FAM25E.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM25A Gene

Genomics for FAM25A Gene

Regulatory Elements for FAM25A Gene

Genomic Location for FAM25A Gene

Start:
87,020,289 bp from pter
End:
87,024,730 bp from pter
Size:
4,442 bases
Orientation:
Plus strand

Genomic View for FAM25A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM25A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM25A Gene

Proteins for FAM25A Gene

  • Protein details for FAM25A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B3EWG3-FM25A_HUMAN
    Recommended name:
    Protein FAM25A
    Protein Accession:
    B3EWG3
    Secondary Accessions:
    • B2RV02
    • Q5VTM1

    Protein attributes for FAM25A Gene

    Size:
    89 amino acids
    Molecular mass:
    9320 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI17119.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for FAM25A Gene

Proteomics data for FAM25A Gene at MOPED

Post-translational modifications for FAM25A Gene

No Post-translational modifications

Other Protein References for FAM25A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM25A Gene

Domains for FAM25A Gene

Protein Domains for FAM25A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

B3EWG3

UniProtKB/Swiss-Prot:

FM25A_HUMAN :
  • B3EWG3
Family:
  • Belongs to the FAM25 family.
genes like me logo Genes that share domains with FAM25A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM25A Gene

Function for FAM25A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM25A Gene

Localization for FAM25A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM25A Gene COMPARTMENTS Subcellular localization image for FAM25A gene
Compartment Confidence
cytosol 3
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM25A Gene

Pathways for FAM25A Gene

SuperPathways for FAM25A Gene

No Data Available

Interacting Proteins for FAM25A Gene

Gene Ontology (GO) - Biological Process for FAM25A Gene

None

No data available for Pathways by source for FAM25A Gene

Transcripts for FAM25A Gene

mRNA/cDNA for FAM25A Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM25A Gene

Family with sequence similarity 25, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM25A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM25A Gene

No ASD Table

Relevant External Links for FAM25A Gene

GeneLoc Exon Structure for
FAM25A
ECgene alternative splicing isoforms for
FAM25A

Expression for FAM25A Gene

mRNA expression in normal human tissues for FAM25A Gene

mRNA differential expression in normal tissues according to GTEx for FAM25A Gene

This gene is overexpressed in Esophagus - Mucosa (22.8), Cervix - Ectocervix (8.0), Vagina (7.1), Skin - Sun Exposed (Lower leg) (6.3), and Skin - Not Sun Exposed (Suprapubic) (4.9).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM25A Gene

SOURCE GeneReport for Unigene cluster for FAM25A Gene Hs.729945

genes like me logo Genes that share expressions with FAM25A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM25A Gene

Orthologs for FAM25A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM25A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 100 (a)
OneToMany
cow
(Bos Taurus)
Mammalia -- 36
  • 82 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 70 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Fam25c 36
  • 80 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 66 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 60 (a)
OneToMany
Species with no ortholog for FAM25A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM25A Gene

ENSEMBL:
Gene Tree for FAM25A (if available)
TreeFam:
Gene Tree for FAM25A (if available)

Paralogs for FAM25A Gene

Paralogs for FAM25A Gene

Selected SIMAP similar genes for FAM25A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM25A: view

Variants for FAM25A Gene

Sequence variations from dbSNP and Humsavar for FAM25A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs1815273 -- 87,022,750(-) atggg(A/G)tttca intron-variant
rs1923940 -- 87,018,292(-) CCCAC(C/T)GCAGC upstream-variant-2KB
rs2004419 -- 87,022,551(+) ACTGC(A/G)TTAGG intron-variant
rs2004686 -- 87,023,177(-) gtggc(A/G)cgatc intron-variant
rs2004687 -- 87,023,550(-) agcaa(C/T)ggggt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM25A Gene

Variant ID Type Subtype PubMed ID
dgv310e1 CNV Complex 17122850
dgv311e1 CNV Complex 17122850
dgv312e1 CNV Complex 17122850
nsv428236 CNV Loss 18775914
essv23924 CNV CNV 17122850
dgv313e1 CNV Complex 17122850
dgv314e1 CNV Complex 17122850
esv27213 CNV Loss 19812545
nsv831939 CNV Gain 17160897
nsv8712 CNV Loss 18304495

Relevant External Links for FAM25A Gene

HapMap Linkage Disequilibrium report
FAM25A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM25A Gene

Disorders for FAM25A Gene

No disorders were found for FAM25A Gene.

No data available for UniProtKB/Swiss-Prot for FAM25A Gene

Publications for FAM25A Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM25A Gene

Sources for FAM25A Gene

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