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Aliases for FAM24B Gene

Aliases for FAM24B Gene

  • Family With Sequence Similarity 24 Member B 2 3 5
  • Family With Sequence Similarity 24, Member B 2

External Ids for FAM24B Gene

Previous GeneCards Identifiers for FAM24B Gene

  • GC10M124149
  • GC10M124581
  • GC10M124599
  • GC10M118226

Summaries for FAM24B Gene

GeneCards Summary for FAM24B Gene

FAM24B (Family With Sequence Similarity 24 Member B) is a Protein Coding gene. An important paralog of this gene is FAM24A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM24B Gene

Genomics for FAM24B Gene

Regulatory Elements for FAM24B Gene

Enhancers for FAM24B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F122849 0.8 Ensembl ENCODE 11.4 +26.1 26095 7.7 PKNOX1 INSM2 BMI1 RAD21 GLIS2 SCRT2 ZNF143 FOS ETV6 CREM C10orf88 LOC399815 FAM24B IKZF5 ACADSB CUZD1
GH10F122847 1.1 Ensembl ENCODE 11.4 +31.2 31168 2.1 USF1 RAD51 SCRT2 ZNF341 CEBPB ACADSB LOC399815 FAM24B IKZF5 CUZD1 ENSG00000272135
GH10F122845 0.8 ENCODE 11.4 +33.3 33287 1.9 ELF3 ARID4B DMAP1 ZSCAN9 RARA SP5 MXD4 KAT8 TGIF2 KLF16 ACADSB LOC399815 FAM24B C10orf88 IKZF5 CUZD1 ENSG00000272135
GH10F122331 0.2 ENCODE 10.9 +548.0 548012 0.8 TBP ARID4B DMAP1 ZNF48 DNMT3B RAD21 RARA SLC30A9 CREM MIXL1 IKZF5 FAM24B C10orf88 ARMS2 GC10P122346 BTBD16
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM24B on UCSC Golden Path with GeneCards custom track

Promoters for FAM24B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM24B Gene

122,849,078 bp from pter
122,879,641 bp from pter
30,564 bases
Minus strand

Genomic View for FAM24B Gene

Genes around FAM24B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM24B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM24B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM24B Gene

Proteins for FAM24B Gene

  • Protein details for FAM24B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM24B
    Protein Accession:
    Secondary Accessions:
    • Q5JPG1

    Protein attributes for FAM24B Gene

    94 amino acids
    Molecular mass:
    10147 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM24B Gene

Post-translational modifications for FAM24B Gene

No Post-translational modifications

Other Protein References for FAM24B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM24B Gene

Domains & Families for FAM24B Gene

Protein Domains for FAM24B Gene


Suggested Antigen Peptide Sequences for FAM24B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM24 family.
  • Belongs to the FAM24 family.
genes like me logo Genes that share domains with FAM24B: view

No data available for Gene Families for FAM24B Gene

Function for FAM24B Gene

genes like me logo Genes that share phenotypes with FAM24B: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM24B Gene

Localization for FAM24B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM24B Gene


Subcellular locations from

Jensen Localization Image for FAM24B Gene COMPARTMENTS Subcellular localization image for FAM24B gene
Compartment Confidence
extracellular 5
plasma membrane 2

Gene Ontology (GO) - Cellular Components for FAM24B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM24B: view

Pathways & Interactions for FAM24B Gene

SuperPathways for FAM24B Gene

No Data Available

Interacting Proteins for FAM24B Gene

Gene Ontology (GO) - Biological Process for FAM24B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM24B Gene

Transcripts for FAM24B Gene

Unigene Clusters for FAM24B Gene

Family with sequence similarity 24, member B:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM24B Gene

No ASD Table

Relevant External Links for FAM24B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM24B Gene

mRNA expression in normal human tissues for FAM24B Gene

mRNA expression in normal human tissues for FAM24B Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM24B Gene:


SOURCE GeneReport for Unigene cluster for FAM24B Gene:

genes like me logo Genes that share expression patterns with FAM24B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM24B Gene

Orthologs for FAM24B Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM24B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC100610674 34
  • 97.75 (n)
FAM24B 35
  • 95 (a)
(Mus musculus)
Mammalia Fam24a 35
  • 41 (a)
1700007K09Rik 35
  • 37 (a)
(Canis familiaris)
Mammalia -- 35
  • 36 (a)
Species where no ortholog for FAM24B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM24B Gene

Gene Tree for FAM24B (if available)
Gene Tree for FAM24B (if available)

Paralogs for FAM24B Gene

Paralogs for FAM24B Gene

(1) SIMAP similar genes for FAM24B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM24B: view

Variants for FAM24B Gene

Sequence variations from dbSNP and Humsavar for FAM24B Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs10794575 -- 122,864,920(+) CACGG(A/G)ATAAT intron-variant
rs10794576 -- 122,868,807(+) ACAAC(C/T)GGTAC intron-variant
rs111377483 -- 122,862,699(+) ACTGG(A/G)TTTTT intron-variant
rs111416260 -- 122,861,998(+) TGCTT(C/T)CTTTC intron-variant
rs111425250 -- 122,863,772(+) TGACT(A/G)TTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM24B Gene

Variant ID Type Subtype PubMed ID
esv3624789 CNV gain 21293372
esv7958 CNV gain 19470904
nsv1054197 CNV loss 25217958
nsv832010 CNV gain 17160897

Variation tolerance for FAM24B Gene

Residual Variation Intolerance Score: 81.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.11; 2.39% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM24B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM24B Gene

Disorders for FAM24B Gene

Relevant External Links for FAM24B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM24B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM24B Gene

Publications for FAM24B Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 64

Products for FAM24B Gene

Sources for FAM24B Gene

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