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Aliases for FAM24A Gene

Aliases for FAM24A Gene

  • Family With Sequence Similarity 24 Member A 2 3 5
  • Family With Sequence Similarity 24, Member A 2

External Ids for FAM24A Gene

Previous GeneCards Identifiers for FAM24A Gene

  • GC10P124211
  • GC10P124660
  • GC10P118289

Summaries for FAM24A Gene

GeneCards Summary for FAM24A Gene

FAM24A (Family With Sequence Similarity 24 Member A) is a Protein Coding gene. An important paralog of this gene is FAM24B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM24A Gene

Genomics for FAM24A Gene

Regulatory Elements for FAM24A Gene

Enhancers for FAM24A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F123358 0.3 FANTOM5 29.8 +447.5 447516 0.2 FAM24A GC10P123367 LOC105378531
GH10F123304 0.5 ENCODE 16.2 +393.5 393469 0.1 PKNOX1 INSM2 FEZF1 GLIS2 ZNF366 SCRT2 KLF7 OVOL3 ZNF488 TSHZ1 ENSG00000234542 FAM24A ENSG00000234677 C10orf120 GC10P123316 GC10P123258
GH10F121926 0.2 ENCODE 16.2 -981.9 -981897 5.3 HDGF PKNOX1 WRNIP1 SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143 SP3 ATE1-AS1 ENSG00000224250 RPL19P16 LINC01153 FAM24A NSMCE4A ATE1 C10orf120 GC10P121933
GH10F122930 0.7 ENCODE 0.3 +20.5 20459 1.7 PKNOX1 CBX3 NFRKB SIN3A FOS ZBTB11 CEBPB REST MBD2 KLF16 ACADSB IKZF5 FAM24A PSTK
GH10F122939 0.4 ENCODE 0.3 +29.1 29093 1.4 MEF2D RFX1 POLR2A ZNF512 ZNF24 PRDM1 RAD21 C10orf88 ACADSB PSTK FAM24A
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM24A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM24A Gene

Chromosome:
10
Start:
122,910,701 bp from pter
End:
122,913,111 bp from pter
Size:
2,411 bases
Orientation:
Plus strand

Genomic View for FAM24A Gene

Genes around FAM24A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM24A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM24A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM24A Gene

Proteins for FAM24A Gene

  • Protein details for FAM24A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NFZ4-FA24A_HUMAN
    Recommended name:
    Protein FAM24A
    Protein Accession:
    A6NFZ4

    Protein attributes for FAM24A Gene

    Size:
    105 amino acids
    Molecular mass:
    11258 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM24A Gene

Post-translational modifications for FAM24A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM24A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM24A Gene

Domains & Families for FAM24A Gene

Protein Domains for FAM24A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM24A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NFZ4

UniProtKB/Swiss-Prot:

FA24A_HUMAN :
  • Belongs to the FAM24 family.
Family:
  • Belongs to the FAM24 family.
genes like me logo Genes that share domains with FAM24A: view

No data available for Gene Families for FAM24A Gene

Function for FAM24A Gene

Phenotypes for FAM24A Gene

GenomeRNAi human phenotypes for FAM24A:
genes like me logo Genes that share phenotypes with FAM24A: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM24A Gene

Localization for FAM24A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM24A Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM24A Gene COMPARTMENTS Subcellular localization image for FAM24A gene
Compartment Confidence
extracellular 5
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM24A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with FAM24A: view

Pathways & Interactions for FAM24A Gene

SuperPathways for FAM24A Gene

No Data Available

Interacting Proteins for FAM24A Gene

Gene Ontology (GO) - Biological Process for FAM24A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM24A Gene

Transcripts for FAM24A Gene

mRNA/cDNA for FAM24A Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
-
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM24A Gene

Family with sequence similarity 24, member A:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM24A Gene

No ASD Table

Relevant External Links for FAM24A Gene

GeneLoc Exon Structure for
FAM24A
ECgene alternative splicing isoforms for
FAM24A

Expression for FAM24A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM24A Gene

mRNA differential expression in normal tissues according to GTEx for FAM24A Gene

This gene is overexpressed in Testis (x52.9).

Protein differential expression in normal tissues from HIPED for FAM24A Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM24A Gene



Protein tissue co-expression partners for FAM24A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM24A Gene:

FAM24A

SOURCE GeneReport for Unigene cluster for FAM24A Gene:

Hs.369829
genes like me logo Genes that share expression patterns with FAM24A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM24A Gene

Orthologs for FAM24A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM24A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM24A 34 35
  • 98.73 (n)
mouse
(Mus musculus)
Mammalia Fam24a 35
  • 50 (a)
ManyToMany
1700007K09Rik 35
  • 39 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 35 (a)
OneToMany
Species where no ortholog for FAM24A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM24A Gene

ENSEMBL:
Gene Tree for FAM24A (if available)
TreeFam:
Gene Tree for FAM24A (if available)

Paralogs for FAM24A Gene

Paralogs for FAM24A Gene

(1) SIMAP similar genes for FAM24A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM24A: view

Variants for FAM24A Gene

Sequence variations from dbSNP and Humsavar for FAM24A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs111633510 -- 122,908,678(+) ATTTA(G/T)AATTG upstream-variant-2KB
rs11248331 -- 122,909,113(+) TCCCA(A/G)TCAAC upstream-variant-2KB
rs113167856 -- 122,908,979(+) TAGTC(-/A)CTTAC upstream-variant-2KB
rs113199180 -- 122,913,169(+) TGTAT(C/T)ACCTA downstream-variant-500B
rs113205866 -- 122,911,348(+) GGCCT(A/G)TGGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM24A Gene

Variant ID Type Subtype PubMed ID
esv6242 OTHER inversion 19470904
nsv1054197 CNV loss 25217958
nsv832010 CNV gain 17160897

Variation tolerance for FAM24A Gene

Residual Variation Intolerance Score: 64% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.67; 14.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM24A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM24A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM24A Gene

Disorders for FAM24A Gene

Relevant External Links for FAM24A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM24A

No disorders were found for FAM24A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM24A Gene

Publications for FAM24A Gene

  1. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4 64

Products for FAM24A Gene

Sources for FAM24A Gene

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