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Aliases for FAM234B Gene

Aliases for FAM234B Gene

  • Family With Sequence Similarity 234 Member B 2 3 5
  • KIAA1467 2 3 4
  • Family With Sequence Similarity 234, Member B 2 3

External Ids for FAM234B Gene

Previous HGNC Symbols for FAM234B Gene

  • KIAA1467

Summaries for FAM234B Gene

GeneCards Summary for FAM234B Gene

FAM234B (Family With Sequence Similarity 234 Member B) is a Protein Coding gene. An important paralog of this gene is FAM234A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM234B Gene

Genomics for FAM234B Gene

Regulatory Elements for FAM234B Gene

Enhancers for FAM234B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM234B on UCSC Golden Path with GeneCards custom track

Promoters for FAM234B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM234B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM234B Gene

13,044,284 bp from pter
13,142,521 bp from pter
98,238 bases
Plus strand

Genomic View for FAM234B Gene

Genes around FAM234B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM234B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM234B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM234B Gene

Proteins for FAM234B Gene

  • Protein details for FAM234B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM234B
    Protein Accession:
    Secondary Accessions:
    • Q49AF2
    • Q5CZ81
    • Q6ZUV7
    • Q9P261

    Protein attributes for FAM234B Gene

    622 amino acids
    Molecular mass:
    67039 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM234B Gene

Proteomics data for FAM234B Gene at MOPED

Post-translational modifications for FAM234B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM234B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM234B Gene

Domains & Families for FAM234B Gene

Protein Domains for FAM234B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM234 family.
  • Belongs to the FAM234 family.
genes like me logo Genes that share domains with FAM234B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM234B Gene

Function for FAM234B Gene

Phenotypes for FAM234B Gene

GenomeRNAi human phenotypes for FAM234B:
genes like me logo Genes that share phenotypes with FAM234B: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM234B Gene

Localization for FAM234B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM234B Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM234B Gene

Pathways & Interactions for FAM234B Gene

SuperPathways for FAM234B Gene

No Data Available

Interacting Proteins for FAM234B Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000197268 for FAM234B Gene via STRING

Gene Ontology (GO) - Biological Process for FAM234B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM234B Gene

Drugs & Compounds for FAM234B Gene

No Compound Related Data Available

Transcripts for FAM234B Gene

Alternative Splicing Database (ASD) splice patterns (SP) for FAM234B Gene

No ASD Table

Relevant External Links for FAM234B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM234B Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM234B Gene

Orthologs for FAM234B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAM234B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KIAA1467 35
  • 85.05 (n)
  • 88.75 (a)
KIAA1467 36
  • 87 (a)
(Canis familiaris)
Mammalia KIAA1467 35
  • 89.55 (n)
  • 90.51 (a)
KIAA1467 36
  • 90 (a)
(Mus musculus)
Mammalia 8430419L09Rik 35
  • 85.32 (n)
  • 87.46 (a)
Fam234b 16
8430419L09Rik 36
  • 87 (a)
(Pan troglodytes)
Mammalia KIAA1467 35
  • 97.36 (n)
  • 97.48 (a)
KIAA1467 36
  • 97 (a)
(Rattus norvegicus)
Mammalia RGD1306151 35
  • 84.78 (n)
  • 86.66 (a)
(Monodelphis domestica)
Mammalia KIAA1467 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 57 (a)
-- 36
  • 60 (a)
(Gallus gallus)
Aves KIAA1467 35
  • 66.61 (n)
  • 64.67 (a)
KIAA1467 36
  • 64 (a)
(Anolis carolinensis)
Reptilia KIAA1467 36
  • 64 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia kiaa1467 35
  • 55.32 (n)
  • 49.43 (a)
(Danio rerio)
Actinopterygii zgc:77415 35
  • 47.81 (n)
  • 38.12 (a)
zgc:77415 36
  • 32 (a)
(Triticum aestivum)
Liliopsida Ta.20842 35
(Zea mays)
Liliopsida Zm.6840 35
Species with no ortholog for FAM234B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • worm (Caenorhabditis elegans)

Evolution for FAM234B Gene

Gene Tree for FAM234B (if available)
Gene Tree for FAM234B (if available)

Paralogs for FAM234B Gene

Paralogs for FAM234B Gene

genes like me logo Genes that share paralogs with FAM234B: view

Variants for FAM234B Gene

Sequence variations from dbSNP and Humsavar for FAM234B Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs10845701 -- 13,047,250(+) GTAGG(A/G)CAGCT intron-variant
rs10845702 -- 13,054,118(+) TTACA(A/G)TCAAT intron-variant
rs10845703 -- 13,072,689(+) CATGC(A/C)ATTGC intron-variant
rs7294408 -- 13,078,977(+) attta(C/T)agatt intron-variant
rs7294646 -- 13,049,085(+) acatc(C/G)GCTAA intron-variant

Variation tolerance for FAM234B Gene

Residual Variation Intolerance Score: 34.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.90; 67.66% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM234B Gene

Disorders for FAM234B Gene

Relevant External Links for FAM234B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM234B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM234B Gene

Publications for FAM234B Gene

  1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10819331) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1. (PMID: 24366813) Hauri S. … Gstaiger M. (Mol. Syst. Biol. 2013) 3
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for FAM234B Gene

Sources for FAM234B Gene