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Aliases for FAM234A Gene

Aliases for FAM234A Gene

  • Family With Sequence Similarity 234 Member A 2 3 5
  • Integrin Alpha FG-GAP Repeat Containing 3 2 3
  • Protein ITFG3 3 4
  • C16orf9 3 4
  • ITFG3 3 4
  • Family With Sequence Similarity 234, Member A 2
  • Chromosome 16 Open Reading Frame 9 2
  • Protein FAM234A 3
  • Gs19 3

External Ids for FAM234A Gene

Previous HGNC Symbols for FAM234A Gene

  • C16orf9
  • ITFG3

Previous GeneCards Identifiers for FAM234A Gene

  • GC16P000319
  • GC16P000328
  • GC16P000354

Summaries for FAM234A Gene

GeneCards Summary for FAM234A Gene

FAM234A (Family With Sequence Similarity 234 Member A) is a Protein Coding gene. An important paralog of this gene is ENSG00000269881.

Gene Wiki entry for FAM234A Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM234A Gene

Genomics for FAM234A Gene

Regulatory Elements for FAM234A Gene

Enhancers for FAM234A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F000200 0.5 ENCODE 21.2 -34.0 -34038 0.9 ZNF362 BHLHE40 INSM2 ZIC2 HIC1 ZNF335 ZFHX2 PRDM10 ZNF600 ZBTB33 FAM234A LUC7L LOC100129478 HBM HBZ NPRL3 ENSG00000228779 GC16P000374 GC16M000176
GH16F000265 0.6 ENCODE 14.8 +31.2 31229 0.9 ZNF687 ESRRA MNT ZNF592 ZFHX2 POLR2A ELK1 ZBTB33 FAM234A ARHGDIG PIR53440
GH16F000250 0.2 ENCODE 12.4 +15.9 15911 0.9 ZFHX2 PRDM10 ZBTB33 EGR2 FAM234A LUC7L HBM HBZ WASH4P ENSG00000269881 PIR53440
GH16F000252 0.9 Ensembl ENCODE 12.3 +18.3 18259 1.6 HDGF HDAC1 CBX3 ARNT EGR1 ZBTB2 ZEB2 TBX21 NR2F2 CREB3 LOC100129478 LUC7L FAM234A HBM HBZ ARHGDIG ENSG00000269881 PIR53440
GH16F000321 0.2 ENCODE 11.8 +87.1 87133 0.8 SCRT1 NFRKB ZIC2 HIC1 SREBF1 ZFHX2 POLR2A MTA1 GLIS1 SCRT2 FAM234A LOC100129478 LUC7L GC16P000365 PIR38678
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM234A on UCSC Golden Path with GeneCards custom track

Promoters for FAM234A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000501944 454 2001 HDGF ARNT WRNIP1 ARID4B SIN3A ZNF2 YY1 ZNF143 ZNF207 ZNF548

Genomic Location for FAM234A Gene

Chromosome:
16
Start:
234,546 bp from pter
End:
269,943 bp from pter
Size:
35,398 bases
Orientation:
Plus strand

Genomic View for FAM234A Gene

Genes around FAM234A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM234A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM234A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM234A Gene

Proteins for FAM234A Gene

  • Protein details for FAM234A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0X4-F234A_HUMAN
    Recommended name:
    Protein FAM234A
    Protein Accession:
    Q9H0X4
    Secondary Accessions:
    • D3DU45
    • Q7L416
    • Q96FR1
    • Q96MC7
    • Q96S30

    Protein attributes for FAM234A Gene

    Size:
    552 amino acids
    Molecular mass:
    59660 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK61220.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM234A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM234A Gene

Post-translational modifications for FAM234A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM234A Gene

Domains & Families for FAM234A Gene

Protein Domains for FAM234A Gene

Suggested Antigen Peptide Sequences for FAM234A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H0X4

UniProtKB/Swiss-Prot:

F234A_HUMAN :
  • Belongs to the FAM234 family.
Family:
  • Belongs to the FAM234 family.
genes like me logo Genes that share domains with FAM234A: view

No data available for Gene Families for FAM234A Gene

Function for FAM234A Gene

Gene Ontology (GO) - Molecular Function for FAM234A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with FAM234A: view
genes like me logo Genes that share phenotypes with FAM234A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for FAM234A

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM234A Gene

Localization for FAM234A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM234A Gene

Membrane; Single-pass type II membrane protein.

Gene Ontology (GO) - Cellular Components for FAM234A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009986 cell surface IDA 19349973
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 20458337
genes like me logo Genes that share ontologies with FAM234A: view

No data available for Subcellular locations from COMPARTMENTS for FAM234A Gene

Pathways & Interactions for FAM234A Gene

SuperPathways for FAM234A Gene

No Data Available

Interacting Proteins for FAM234A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000301678%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000301678 Q9H0X4-F234A_HUMAN for FAM234A Gene via STRING IID

Gene Ontology (GO) - Biological Process for FAM234A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with FAM234A: view

No data available for Pathways by source and SIGNOR curated interactions for FAM234A Gene

Transcripts for FAM234A Gene

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM234A Gene

No ASD Table

Relevant External Links for FAM234A Gene

GeneLoc Exon Structure for
FAM234A
ECgene alternative splicing isoforms for
FAM234A

Expression for FAM234A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of FAM234A Gene:

FAM234A
genes like me logo Genes that share expression patterns with FAM234A: view

Primer Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM234A Gene

Orthologs for FAM234A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM234A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ITFG3 34
  • 97.95 (n)
-- 35
  • 97 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Itfg3 34 35
  • 77.62 (n)
Fam234a 16
dog
(Canis familiaris)
Mammalia ITFG3 34
  • 77.37 (n)
-- 35
  • 71 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Itfg3 34
  • 77.11 (n)
cow
(Bos Taurus)
Mammalia ITFG3 34 35
  • 75.32 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 48 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 45 (a)
OneToMany
chicken
(Gallus gallus)
Aves ITFG3 34
  • 57.72 (n)
-- 35
  • 51 (a)
ManyToMany
-- 35
  • 45 (a)
ManyToMany
-- 35
  • 44 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 35 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia itfg3 34
  • 52.42 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC796439 34
  • 46.56 (n)
ITFG3 35
  • 30 (a)
OneToMany
Species where no ortholog for FAM234A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM234A Gene

ENSEMBL:
Gene Tree for FAM234A (if available)
TreeFam:
Gene Tree for FAM234A (if available)

Paralogs for FAM234A Gene

Paralogs for FAM234A Gene

genes like me logo Genes that share paralogs with FAM234A: view

Variants for FAM234A Gene

Sequence variations from dbSNP and Humsavar for FAM234A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1017017 -- 259,356(+) AAGCC(A/C)CCGTC intron-variant
rs1043102 -- 264,997(+) CTCCC(A/G/T)GCTGC intron-variant, reference, missense
rs1043103 -- 264,998(+) TCCCG(G/T)CTGCG intron-variant, reference, synonymous-codon
rs1043177 -- 266,023(+) AGCTT(C/T)GTAGC intron-variant, utr-variant-3-prime
rs1043184 -- 266,048(+) GACCC(A/C)CCCAC intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for FAM234A Gene

Variant ID Type Subtype PubMed ID
dgv1479e59 CNV duplication 20981092
dgv32n68 CNV loss 17160897
esv1473294 CNV insertion 17803354
esv2422427 CNV duplication 17116639
esv2660459 CNV deletion 23128226
esv2667528 CNV deletion 23128226
esv2961 CNV loss 18987735
esv3393842 CNV duplication 20981092
esv3570031 CNV gain 25503493
esv3637558 CNV loss 21293372
esv3637559 CNV loss 21293372
esv3637560 CNV loss 21293372
esv3637561 CNV loss 21293372
esv3637562 CNV gain 21293372
esv3637563 CNV gain 21293372
nsv1044142 CNV gain 25217958
nsv1070307 CNV deletion 25765185
nsv1120314 CNV tandem duplication 24896259
nsv1120315 CNV tandem duplication 24896259
nsv1140309 OTHER inversion 24896259
nsv1147155 CNV insertion 26484159
nsv518291 CNV loss 19592680
nsv827477 CNV gain 20364138
nsv977893 CNV duplication 23825009

Variation tolerance for FAM234A Gene

Residual Variation Intolerance Score: 77.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.43; 54.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM234A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM234A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM234A Gene

Disorders for FAM234A Gene

Relevant External Links for FAM234A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM234A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM234A

No disorders were found for FAM234A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM234A Gene

Publications for FAM234A Gene

  1. Mass-spectrometric identification and relative quantification of N- linked cell surface glycoproteins. (PMID: 19349973) Wollscheid B. … Watts J.D. (Nat. Biotechnol. 2009) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PMID: 11157797) Daniels R.J. … Higgs D.R. (Hum. Mol. Genet. 2001) 3 4 64
  5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 64

Products for FAM234A Gene

Sources for FAM234A Gene

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