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Aliases for FAM234A Gene

Aliases for FAM234A Gene

  • Family With Sequence Similarity 234 Member A 2 3 5
  • Family With Sequence Similarity 234, Member A 2 3
  • Integrin Alpha FG-GAP Repeat Containing 3 2 3
  • Protein ITFG3 3 4
  • C16orf9 3 4
  • ITFG3 3 4
  • Chromosome 16 Open Reading Frame 9 2
  • Gs19 3

External Ids for FAM234A Gene

Previous HGNC Symbols for FAM234A Gene

  • C16orf9
  • ITFG3

Previous GeneCards Identifiers for FAM234A Gene

  • GC16P000319

Summaries for FAM234A Gene

GeneCards Summary for FAM234A Gene

FAM234A (Family With Sequence Similarity 234 Member A) is a Protein Coding gene. An important paralog of this gene is ENSG00000269881.

Gene Wiki entry for FAM234A Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM234A Gene

Genomics for FAM234A Gene

Regulatory Elements for FAM234A Gene

Promoters for FAM234A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM234A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM234A Gene

Chromosome:
16
Start:
234,546 bp from pter
End:
269,943 bp from pter
Size:
35,398 bases
Orientation:
Plus strand

Genomic View for FAM234A Gene

Genes around FAM234A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM234A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM234A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM234A Gene

Proteins for FAM234A Gene

  • Protein details for FAM234A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H0X4-F234A_HUMAN
    Recommended name:
    Protein FAM234A
    Protein Accession:
    Q9H0X4
    Secondary Accessions:
    • D3DU45
    • Q7L416
    • Q96FR1
    • Q96MC7
    • Q96S30

    Protein attributes for FAM234A Gene

    Size:
    552 amino acids
    Molecular mass:
    59660 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAK61220.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM234A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM234A Gene

Proteomics data for FAM234A Gene at MOPED

Post-translational modifications for FAM234A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM234A Gene

Domains & Families for FAM234A Gene

Protein Domains for FAM234A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM234A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H0X4

UniProtKB/Swiss-Prot:

F234A_HUMAN :
  • Belongs to the FAM234 family.
Family:
  • Belongs to the FAM234 family.
genes like me logo Genes that share domains with FAM234A: view

No data available for Gene Families for FAM234A Gene

Function for FAM234A Gene

genes like me logo Genes that share phenotypes with FAM234A: view

Animal Model Products

  • Taconic Biosciences Mouse Models for FAM234A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM234A Gene

Localization for FAM234A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM234A Gene

Membrane; Single-pass type II membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM234A Gene

Pathways & Interactions for FAM234A Gene

SuperPathways for FAM234A Gene

No Data Available

Interacting Proteins for FAM234A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000301678%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q9H0X4-F234A_HUMAN ENSP00000301678 for FAM234A Gene via I2D STRING

Gene Ontology (GO) - Biological Process for FAM234A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM234A Gene

Drugs & Compounds for FAM234A Gene

No Compound Related Data Available

Transcripts for FAM234A Gene

Alternative Splicing Database (ASD) splice patterns (SP) for FAM234A Gene

No ASD Table

Relevant External Links for FAM234A Gene

GeneLoc Exon Structure for
FAM234A
ECgene alternative splicing isoforms for
FAM234A

Expression for FAM234A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with FAM234A: view

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM234A Gene

Orthologs for FAM234A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM234A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ITFG3 35
  • 75.32 (n)
  • 68.6 (a)
ITFG3 36
  • 68 (a)
OneToMany
dog
(Canis familiaris)
Mammalia ITFG3 35
  • 77.37 (n)
  • 71.69 (a)
-- 36
  • 71 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Itfg3 35
  • 77.62 (n)
  • 73.68 (a)
Fam234a 16
Itfg3 36
  • 73 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia ITFG3 35
  • 97.95 (n)
  • 97.46 (a)
-- 36
  • 97 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 48 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 45 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Itfg3 35
  • 77.11 (n)
  • 72.46 (a)
chicken
(Gallus gallus)
Aves ITFG3 35
  • 57.72 (n)
  • 46.14 (a)
-- 36
  • 44 (a)
ManyToMany
-- 36
  • 51 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 35 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia itfg3 35
  • 52.42 (n)
  • 42.08 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC796439 35
  • 46.56 (n)
  • 33.4 (a)
ITFG3 36
  • 30 (a)
OneToMany
Species with no ortholog for FAM234A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM234A Gene

ENSEMBL:
Gene Tree for FAM234A (if available)
TreeFam:
Gene Tree for FAM234A (if available)

Paralogs for FAM234A Gene

Paralogs for FAM234A Gene

genes like me logo Genes that share paralogs with FAM234A: view

Variants for FAM234A Gene

Sequence variations from dbSNP and Humsavar for FAM234A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs8816 -- 265,840(+) GCTCT(A/G)TCCCT intron-variant, utr-variant-3-prime
rs13001 -- 266,054(-) TCCTT(A/G)GTGGG intron-variant, utr-variant-3-prime
rs916195 -- 242,046(+) GTGGT(A/G)TTCCT intron-variant
rs1203972 -- 233,233(-) tggtg(A/G)cgggc upstream-variant-2KB
rs1203973 -- 232,571(-) GGCCG(A/G)GGGga upstream-variant-2KB

Variation tolerance for FAM234A Gene

Residual Variation Intolerance Score: 77.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.43; 54.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM234A Gene

HapMap Linkage Disequilibrium report
FAM234A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM234A Gene

Disorders for FAM234A Gene

Relevant External Links for FAM234A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM234A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM234A

No disorders were found for FAM234A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM234A Gene

Publications for FAM234A Gene

  1. Mass-spectrometric identification and relative quantification of N- linked cell surface glycoproteins. (PMID: 19349973) Wollscheid B. … Watts J.D. (Nat. Biotechnol. 2009) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. (PMID: 23446634) Chen Z. … Reiner A.P. (Hum. Mol. Genet. 2013) 3
  4. Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study. (PMID: 23696099) Ding K. … Kullo I.J. (G3 (Bethesda) 2013) 3
  5. Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. (PMID: 22268729) Liu B. … Wang L.S. (J. Proteome Res. 2012) 3

Products for FAM234A Gene

Sources for FAM234A Gene

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