Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM231B Gene

Aliases for FAM231B Gene

  • Family With Sequence Similarity 231 Member B 2 3
  • Family With Sequence Similarity 231, Member B 2
  • Family With Sequence Similarity 231 Member C 5
  • FAM231C 5

External Ids for FAM231B Gene

Previous GeneCards Identifiers for FAM231B Gene

  • GC01P016865

Summaries for FAM231B Gene

GeneCards Summary for FAM231B Gene

FAM231B (Family With Sequence Similarity 231 Member B) is a Protein Coding gene. An important paralog of this gene is FAM231A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM231B Gene

Genomics for FAM231B Gene

Regulatory Elements for FAM231B Gene

Enhancers for FAM231B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM231B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM231B Gene

16,538,724 bp from pter
16,540,035 bp from pter
1,312 bases
Plus strand

Genomic View for FAM231B Gene

Genes around FAM231B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM231B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM231B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM231B Gene

Proteins for FAM231B Gene

  • Protein details for FAM231B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM231B
    Protein Accession:

    Protein attributes for FAM231B Gene

    169 amino acids
    Molecular mass:
    18250 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM231B Gene

Proteomics data for FAM231B Gene at MOPED

Post-translational modifications for FAM231B Gene

No Post-translational modifications

Other Protein References for FAM231B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM231B Gene

Domains & Families for FAM231B Gene

Protein Domains for FAM231B Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM231 family.
  • Belongs to the FAM231 family.
genes like me logo Genes that share domains with FAM231B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM231B Gene

Function for FAM231B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM231B Gene

Localization for FAM231B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM231B Gene

Pathways & Interactions for FAM231B Gene

SuperPathways for FAM231B Gene

No Data Available

Interacting Proteins for FAM231B Gene

Gene Ontology (GO) - Biological Process for FAM231B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM231B Gene

Drugs & Compounds for FAM231B Gene

No Compound Related Data Available

Transcripts for FAM231B Gene

mRNA/cDNA for FAM231B Gene

(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM231B Gene

No ASD Table

Relevant External Links for FAM231B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM231B Gene

mRNA differential expression in normal tissues according to GTEx for FAM231B Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x22.7) and Brain - Cerebellum (x15.7).

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM231B Gene

Orthologs for FAM231B Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM231B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC745889 35
  • 98.62 (n)
  • 97.04 (a)
-- 36
  • 99 (a)
Species with no ortholog for FAM231B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM231B Gene

Gene Tree for FAM231B (if available)
Gene Tree for FAM231B (if available)

Paralogs for FAM231B Gene

Paralogs for FAM231B Gene

(3) SIMAP similar genes for FAM231B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM231B: view

Variants for FAM231B Gene

Sequence variations from dbSNP and Humsavar for FAM231B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs149613 -- 16,537,592(+) cacgc(C/T)gctga upstream-variant-2KB
rs156879 -- 16,538,035(+) TCTGA(C/T)TTTAA upstream-variant-2KB
rs156880 -- 16,539,538(+) GATTC(C/T)CCCTG reference, missense
rs156881 -- 16,539,802(-) AGTTA(A/T)GCAGC utr-variant-3-prime
rs156882 -- 16,540,531(+) cttcc(C/T)ttttt downstream-variant-500B

Variation tolerance for FAM231B Gene

Gene Damage Index Score: 1.21; 24.40% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM231B Gene

Disorders for FAM231B Gene

Relevant External Links for FAM231B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM231B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM231B Gene

Publications for FAM231B Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67

Products for FAM231B Gene

Sources for FAM231B Gene