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Aliases for FAM231A Gene

Aliases for FAM231A Gene

  • Family With Sequence Similarity 231 Member A 2 3 5
  • UPF0627 Protein ENSP00000341061/ENSP00000339743 3
  • Family With Sequence Similarity 231, Member A 2
  • Protein FAM231A/C 3
  • Protein FAM231A 3
  • FAM231C 3

External Ids for FAM231A Gene

Previous GeneCards Identifiers for FAM231A Gene

  • GC01P017001

Summaries for FAM231A Gene

GeneCards Summary for FAM231A Gene

FAM231A (Family With Sequence Similarity 231 Member A) is a Protein Coding gene. An important paralog of this gene is FAM231C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM231A Gene

Genomics for FAM231A Gene

Regulatory Elements for FAM231A Gene

Enhancers for FAM231A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F015791 1.8 FANTOM5 Ensembl ENCODE 22.1 -875.5 -875501 11.3 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 TBX21 CLCNKA HSPB7 FAM231A FBLIM1 CD24P1 RNU1-1 ENSG00000233078 FAM131C ARHGEF19-AS1 ENSG00000237301
GH01F015829 1.8 FANTOM5 Ensembl ENCODE 22.1 -839.0 -839003 10.0 CREB3L1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC TBX21 FAM231A ENSG00000237938 CD24P1 RNU1-1 CLCNKA FLJ37453 SPEN ZBTB17 HSPB7 RPL22P3
GH01F016121 1.3 Ensembl ENCODE 22.1 -550.0 -550021 2.5 FEZF1 ZNF2 ZNF121 GLIS2 KLF7 ZNF263 SP3 TSHZ1 ZNF488 TBX21 FAM231A RNU1-1 CD24P1 LOC100421279 ENSG00000224621 FAM131C ARHGEF19-AS1 ENSG00000237301 SPATA21 CLCNKB
GH01F016111 1.3 Ensembl ENCODE 22.1 -560.5 -560541 2.3 HDGF MLX ZNF133 ARID4B GLI4 ZNF48 ZNF2 GLIS2 ZNF416 ZNF548 SPEN FAM231A RPL22P3 RNU1-1 CD24P1 LOC100421279 ENSG00000237938 LINC01772 RPS16P1 SPATA21
GH01F016642 1.2 ENCODE 22.3 -28.3 -28346 3.5 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TBX21 MFAP2 FAM231A FBLIM1 RNU1-1 LOC100421279 ENSG00000224621 ENSG00000227959 EPHA2 RPL22P3 RSG1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM231A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM231A Gene

Chromosome:
1
Start:
16,673,003 bp from pter
End:
16,673,512 bp from pter
Size:
510 bases
Orientation:
Plus strand

Genomic View for FAM231A Gene

Genes around FAM231A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM231A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM231A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM231A Gene

Proteins for FAM231A Gene

  • Protein details for FAM231A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0DMU4-F231A_HUMAN
    Recommended name:
    Protein FAM231A
    Protein Accession:
    P0DMU4
    Secondary Accessions:
    • A6NEA5

    Protein attributes for FAM231A Gene

    Size:
    169 amino acids
    Molecular mass:
    18266 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM231A Gene

Post-translational modifications for FAM231A Gene

No Post-translational modifications

Other Protein References for FAM231A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM231A Gene

Domains & Families for FAM231A Gene

Protein Domains for FAM231A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P0DMU4

UniProtKB/Swiss-Prot:

F231A_HUMAN :
  • Belongs to the FAM231 family.
Family:
  • Belongs to the FAM231 family.
genes like me logo Genes that share domains with FAM231A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM231A Gene

Function for FAM231A Gene

Phenotypes for FAM231A Gene

GenomeRNAi human phenotypes for FAM231A:
genes like me logo Genes that share phenotypes with FAM231A: view

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM231A Gene

Localization for FAM231A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM231A Gene

Pathways & Interactions for FAM231A Gene

SuperPathways for FAM231A Gene

No Data Available

Interacting Proteins for FAM231A Gene

Gene Ontology (GO) - Biological Process for FAM231A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM231A Gene

Transcripts for FAM231A Gene

mRNA/cDNA for FAM231A Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM231A Gene

No ASD Table

Relevant External Links for FAM231A Gene

GeneLoc Exon Structure for
FAM231A
ECgene alternative splicing isoforms for
FAM231A

Expression for FAM231A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM231A Gene

mRNA differential expression in normal tissues according to GTEx for FAM231A Gene

This gene is overexpressed in Testis (x11.0), Brain - Cerebellar Hemisphere (x8.5), Brain - Cerebellum (x6.8), Liver (x4.4), and Pancreas (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of FAM231A Gene:

FAM231A
genes like me logo Genes that share expression patterns with FAM231A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM231A Gene

Orthologs for FAM231A Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for FAM231A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC745683 34
  • 99.8 (n)
-- 35
  • 99 (a)
OneToMany
Species where no ortholog for FAM231A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM231A Gene

ENSEMBL:
Gene Tree for FAM231A (if available)
TreeFam:
Gene Tree for FAM231A (if available)

Paralogs for FAM231A Gene

Paralogs for FAM231A Gene

(2) SIMAP similar genes for FAM231A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM231A: view

Variants for FAM231A Gene

Sequence variations from dbSNP and Humsavar for FAM231A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111246417 -- 16,673,933(+) AAAAA(A/C)AAGAA downstream-variant-500B
rs112759166 -- 16,673,414(+) CCTCC(C/T)ACCCA reference, missense
rs11485899 -- 16,671,083(-) GTACT(C/G)CATCC upstream-variant-2KB
rs12042426 -- 16,673,638(+) AGAGA(C/T)AACTg downstream-variant-500B
rs199578754 -- 16,671,280(+) TGGGG(C/G)ATCCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM231A Gene

Variant ID Type Subtype PubMed ID
nsv954849 CNV duplication 24416366
nsv954848 CNV duplication 24416366
nsv945797 CNV duplication 23825009
nsv945795 CNV duplication 23825009
nsv945573 CNV duplication 23825009
nsv9324 CNV gain+loss 18304495
nsv829625 CNV gain 20364138
nsv821743 CNV gain 20364138
nsv821511 CNV duplication 20802225
nsv7173 OTHER inversion 18451855
nsv545667 CNV loss 21841781
nsv499577 OTHER inversion 21111241
nsv471655 CNV gain+loss 15918152
nsv469795 CNV gain+loss 16826518
nsv437206 CNV loss 16327808
nsv436652 OTHER inversion 17901297
nsv428421 CNV gain+loss 18775914
nsv3965 CNV insertion 18451855
nsv1161259 CNV duplication 26073780
nsv1161255 CNV duplication 26073780
nsv1161242 CNV duplication 26073780
nsv1150135 CNV duplication 26484159
nsv1145756 CNV duplication 26484159
nsv1116446 OTHER inversion 24896259
nsv1077283 CNV duplication 25765185
nsv1075777 CNV duplication 25765185
nsv1013011 CNV gain 25217958
nsv1009050 CNV loss 25217958
nsv1008129 CNV gain+loss 25217958
nsv1004978 CNV gain+loss 25217958
nsv1004807 CNV gain+loss 25217958
esv3892414 CNV gain 25118596
esv3577752 CNV loss 25503493
esv34697 CNV gain 17911159
esv3423215 CNV duplication 20981092
esv33965 CNV gain+loss 17666407
esv3372391 CNV duplication 20981092
esv33046 CNV loss 17666407
esv29948 CNV loss 18421352
esv29642 CNV gain+loss 19812545
esv2758925 CNV gain+loss 17122850
esv2750816 CNV gain 17911159
dgv93n100 CNV gain 25217958
dgv92n100 CNV gain 25217958
dgv91n100 CNV gain+loss 25217958
dgv90n100 CNV gain 25217958
dgv89n100 CNV gain+loss 25217958
dgv87n100 CNV loss 25217958
dgv86n100 CNV gain 25217958
dgv85n100 CNV gain 25217958
dgv83n100 CNV loss 25217958
dgv82n100 CNV gain+loss 25217958
dgv78n100 CNV loss 25217958
dgv77n100 CNV loss 25217958
dgv76n100 CNV gain 25217958
dgv75n100 CNV gain 25217958
dgv74n100 CNV gain 25217958
dgv73n100 CNV gain 25217958
dgv72n100 CNV gain+loss 25217958
dgv71n100 CNV loss 25217958
dgv70n100 CNV gain+loss 25217958
dgv68n100 CNV gain 25217958
dgv66n100 CNV gain 25217958
dgv65n100 CNV gain 25217958
dgv63n100 CNV gain 25217958
dgv62n100 CNV gain 25217958
dgv61n100 CNV gain+loss 25217958
dgv60n100 CNV loss 25217958
dgv59n100 CNV gain 25217958
dgv55n100 CNV gain+loss 25217958
dgv54n100 CNV gain 25217958
dgv53n100 CNV loss 25217958
dgv52n100 CNV gain+loss 25217958
dgv52e59 CNV duplication 20981092
dgv51n100 CNV loss 25217958
dgv51e59 CNV duplication 20981092
dgv50n106 CNV duplication 24896259
dgv50n100 CNV gain 25217958
dgv49n106 CNV duplication 24896259
dgv49n100 CNV loss 25217958
dgv49e59 CNV duplication 20981092
dgv48n100 CNV gain+loss 25217958
dgv45n100 CNV gain 25217958
dgv42n100 CNV loss 25217958
dgv41n100 CNV gain 25217958
dgv39n100 CNV gain 25217958
dgv22n67 CNV gain 20364138
dgv21n67 CNV gain 20364138
dgv21e199 CNV deletion 23128226
dgv20n67 CNV gain 20364138
dgv1e203 CNV gain+loss 21179565
dgv164n54 CNV loss 21841781
dgv10e201 CNV deletion 23290073

Relevant External Links for FAM231A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM231A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM231A Gene

Disorders for FAM231A Gene

Relevant External Links for FAM231A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM231A

No disorders were found for FAM231A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM231A Gene

Publications for FAM231A Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64

Products for FAM231A Gene

Sources for FAM231A Gene

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