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Aliases for FAM229B Gene

Aliases for FAM229B Gene

  • Family With Sequence Similarity 229, Member B 2 3
  • C6orf225 3 4
  • Chromosome 6 Open Reading Frame 225 2
  • UPF0731 Protein C6orf225 3

External Ids for FAM229B Gene

Previous HGNC Symbols for FAM229B Gene

  • C6orf225

Previous GeneCards Identifiers for FAM229B Gene

  • GC06P112409

Summaries for FAM229B Gene

GeneCards Summary for FAM229B Gene

FAM229B (Family With Sequence Similarity 229, Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM229B Gene

Genomics for FAM229B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM229B Gene

112,087,471 bp from pter
112,102,790 bp from pter
15,320 bases
Plus strand

Genomic View for FAM229B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM229B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM229B Gene

No data available for Regulatory Elements for FAM229B Gene

Proteins for FAM229B Gene

  • Protein details for FAM229B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM229B
    Protein Accession:
    Secondary Accessions:
    • B8ZZ33

    Protein attributes for FAM229B Gene

    80 amino acids
    Molecular mass:
    8717 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM229B Gene

Proteomics data for FAM229B Gene at MOPED

Post-translational modifications for FAM229B Gene

No Post-translational modifications

Other Protein References for FAM229B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM229B Gene

Domains & Families for FAM229B Gene

Protein Domains for FAM229B Gene


Suggested Antigen Peptide Sequences for FAM229B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM229 family.
  • Belongs to the FAM229 family.
genes like me logo Genes that share domains with FAM229B: view

No data available for Gene Families for FAM229B Gene

Function for FAM229B Gene

Phenotypes for FAM229B Gene

GenomeRNAi human phenotypes for FAM229B:
genes like me logo Genes that share phenotypes with FAM229B: view

Animal Model Products

miRNA for FAM229B Gene

miRTarBase miRNAs that target FAM229B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM229B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM229B Gene

Localization for FAM229B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM229B Gene

Pathways & Interactions for FAM229B Gene

SuperPathways for FAM229B Gene

No Data Available

Interacting Proteins for FAM229B Gene

Gene Ontology (GO) - Biological Process for FAM229B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM229B Gene

Drugs & Compounds for FAM229B Gene

No Compound Related Data Available

Transcripts for FAM229B Gene

mRNA/cDNA for FAM229B Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM229B Gene

Family with sequence similarity 229, member B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM229B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM229B Gene

No ASD Table

Relevant External Links for FAM229B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM229B Gene

mRNA expression in normal human tissues for FAM229B Gene

mRNA differential expression in normal tissues according to GTEx for FAM229B Gene

This gene is overexpressed in Testis (x8.7) and Brain - Spinal cord (cervical c-1) (x4.2).

Protein differential expression in normal tissues from HIPED for FAM229B Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM229B Gene

SOURCE GeneReport for Unigene cluster for FAM229B Gene Hs.591340

genes like me logo Genes that share expression patterns with FAM229B: view

Protein tissue co-expression partners for FAM229B Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM229B Gene

Orthologs for FAM229B Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM229B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM229B 35
  • 90.83 (n)
  • 92.5 (a)
FAM229B 36
  • 93 (a)
(Canis familiaris)
Mammalia C12H6orf225 35
  • 93.75 (n)
  • 93.75 (a)
FAM229B 36
  • 94 (a)
(Mus musculus)
Mammalia Fam229b 35
  • 89.58 (n)
  • 90 (a)
Fam229b 16
Fam229b 36
  • 90 (a)
(Pan troglodytes)
Mammalia C6H6orf225 35
  • 97.92 (n)
  • 96.25 (a)
FAM229B 36
  • 96 (a)
(Rattus norvegicus)
Mammalia Fam229b 35
  • 90.42 (n)
  • 90 (a)
(Monodelphis domestica)
Mammalia FAM229B 36
  • 86 (a)
Species with no ortholog for FAM229B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM229B Gene

Gene Tree for FAM229B (if available)
Gene Tree for FAM229B (if available)

Paralogs for FAM229B Gene

(1) SIMAP similar genes for FAM229B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM229B: view

No data available for Paralogs for FAM229B Gene

Variants for FAM229B Gene

Sequence variations from dbSNP and Humsavar for FAM229B Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs916429 -- 112,100,602(+) AACTT(C/T)GGTGC intron-variant
rs2213842 -- 112,102,607(+) agcaa(A/C/G/T)atatt utr-variant-3-prime
rs2227238 -- 112,102,954(+) CTCTG(C/T)GTCCC downstream-variant-500B
rs2345804 -- 112,092,259(+) acatt(A/G)taatc intron-variant
rs6901156 -- 112,102,059(+) aagat(C/G)atctc utr-variant-3-prime

Variation tolerance for FAM229B Gene

Residual Variation Intolerance Score: 76.09% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.18; 51.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM229B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM229B Gene

Disorders for FAM229B Gene

Relevant External Links for FAM229B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM229B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM229B Gene

Publications for FAM229B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 67
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for FAM229B Gene

Sources for FAM229B Gene

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