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Aliases for FAM228B Gene

Aliases for FAM228B Gene

  • Family With Sequence Similarity 228, Member B 2 3

External Ids for FAM228B Gene

Previous GeneCards Identifiers for FAM228B Gene

  • GC02P024302

Summaries for FAM228B Gene

GeneCards Summary for FAM228B Gene

FAM228B (Family With Sequence Similarity 228, Member B) is a Protein Coding gene. An important paralog of this gene is FAM228A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM228B Gene

Genomics for FAM228B Gene

Genomic Location for FAM228B Gene

Start:
24,076,526 bp from pter
End:
24,169,640 bp from pter
Size:
93,115 bases
Orientation:
Plus strand

Genomic View for FAM228B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM228B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM228B Gene

No data available for Regulatory Elements for FAM228B Gene

Proteins for FAM228B Gene

  • Protein details for FAM228B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C875-F228B_HUMAN
    Recommended name:
    Protein FAM228B
    Protein Accession:
    P0C875
    Secondary Accessions:

    Protein attributes for FAM228B Gene

    Size:
    321 amino acids
    Molecular mass:
    37405 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AK055413; Type=Frameshift; Positions=267; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM228B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM228B Gene

Proteomics data for FAM228B Gene at MOPED

Post-translational modifications for FAM228B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM228B Gene

No data available for DME Specific Peptides for FAM228B Gene

Domains for FAM228B Gene

Protein Domains for FAM228B Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P0C875

UniProtKB/Swiss-Prot:

F228B_HUMAN :
  • P0C875
Family:
  • Belongs to the FAM228 family.
genes like me logo Genes that share domains with FAM228B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM228B Gene

Function for FAM228B Gene

Phenotypes for FAM228B Gene

GenomeRNAi human phenotypes for FAM228B:
genes like me logo Genes that share phenotypes with FAM228B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM228B Gene

Localization for FAM228B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM228B Gene

Pathways for FAM228B Gene

SuperPathways for FAM228B Gene

No Data Available

Interacting Proteins for FAM228B Gene

Gene Ontology (GO) - Biological Process for FAM228B Gene

None

No data available for Pathways by source for FAM228B Gene

Transcripts for FAM228B Gene

mRNA/cDNA for FAM228B Gene

Unigene Clusters for FAM228B Gene

Family with sequence similarity 228, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM228B Gene

No ASD Table

Relevant External Links for FAM228B Gene

GeneLoc Exon Structure for
FAM228B
ECgene alternative splicing isoforms for
FAM228B

Expression for FAM228B Gene

mRNA expression in normal human tissues for FAM228B Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM228B Gene

SOURCE GeneReport for Unigene cluster for FAM228B Gene Hs.710370

genes like me logo Genes that share expressions with FAM228B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM228B Gene

Orthologs for FAM228B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM228B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 94 (a)
OneToMany
FAM228B 35
  • 99.38 (n)
  • 99.07 (a)
cow
(Bos Taurus)
Mammalia FAM228B 35
  • 86.18 (n)
  • 77.91 (a)
FAM228B 36
  • 76 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 71 (a)
OneToMany
FAM228B 35
  • 84.03 (n)
  • 74.12 (a)
mouse
(Mus musculus)
Mammalia Fam228b 35
  • 84.13 (n)
  • 79.04 (a)
Fam228b 16
Fam228b 36
  • 78 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 17 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 39 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam228b 35
  • 79.11 (n)
  • 71.43 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 32 (a)
OneToMany
LOC421978 35
  • 57 (n)
  • 42.51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam228b 35
  • 51.52 (n)
  • 41.36 (a)
zebrafish
(Danio rerio)
Actinopterygii fam228a 35
  • 48.28 (n)
  • 34.55 (a)
fam228a 36
  • 26 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 19 (a)
OneToMany
Species with no ortholog for FAM228B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM228B Gene

ENSEMBL:
Gene Tree for FAM228B (if available)
TreeFam:
Gene Tree for FAM228B (if available)

Paralogs for FAM228B Gene

Paralogs for FAM228B Gene

Selected SIMAP similar genes for FAM228B Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with FAM228B: view

Variants for FAM228B Gene

Sequence variations from dbSNP and Humsavar for FAM228B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs1025078 -- 24,104,316(+) GACGT(A/T)TTATA intron-variant
rs1025079 -- 24,104,320(+) TATTA(C/T)AGGGC intron-variant
rs1112118 -- 24,107,722(-) agttt(C/G)aaaga intron-variant
rs1112353 -- 24,107,590(-) gtgct(A/G)tggtc intron-variant
rs1115856 -- 24,153,761(+) caaca(C/T)gagga intron-variant

Relevant External Links for FAM228B Gene

HapMap Linkage Disequilibrium report
FAM228B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM228B Gene

Disorders for FAM228B Gene

No disorders were found for FAM228B Gene.

No data available for UniProtKB/Swiss-Prot for FAM228B Gene

Publications for FAM228B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for FAM228B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM228B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM228B
    • Block miRNA regulation of FAM228B using miScript Target Protectors

    Sources for FAM228B Gene

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