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Aliases for FAM228A Gene

Aliases for FAM228A Gene

  • Family With Sequence Similarity 228, Member A 2 3
  • C2orf84 3 4
  • Chromosome 2 Open Reading Frame 84 2
  • UPF0638 Protein C2orf84 3
  • Protein FAM228A 3

External Ids for FAM228A Gene

Previous HGNC Symbols for FAM228A Gene

  • C2orf84

Previous GeneCards Identifiers for FAM228A Gene

  • GC02P024399

Summaries for FAM228A Gene

GeneCards Summary for FAM228A Gene

FAM228A (Family With Sequence Similarity 228, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM228A Gene

Genomics for FAM228A Gene

Genomic Location for FAM228A Gene

24,175,069 bp from pter
24,200,849 bp from pter
25,781 bases
Plus strand

Genomic View for FAM228A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM228A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM228A Gene

No data available for Regulatory Elements for FAM228A Gene

Proteins for FAM228A Gene

  • Protein details for FAM228A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM228A
    Protein Accession:
    Secondary Accessions:

    Protein attributes for FAM228A Gene

    206 amino acids
    Molecular mass:
    23752 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM228A Gene

Proteomics data for FAM228A Gene at MOPED

Post-translational modifications for FAM228A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM228A Gene

No data available for DME Specific Peptides for FAM228A Gene

Domains for FAM228A Gene

Protein Domains for FAM228A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM228 family.
  • Belongs to the FAM228 family.
genes like me logo Genes that share domains with FAM228A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM228A Gene

Function for FAM228A Gene

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM228A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM228A Gene

Localization for FAM228A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM228A Gene

Pathways for FAM228A Gene

SuperPathways for FAM228A Gene

No Data Available

Interacting Proteins for FAM228A Gene

Gene Ontology (GO) - Biological Process for FAM228A Gene


No data available for Pathways by source for FAM228A Gene

Transcripts for FAM228A Gene

mRNA/cDNA for FAM228A Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM228A Gene

Family with sequence similarity 228, member A:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM228A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM228A Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9
SP1: - - -
SP2: -
SP3: - -

Relevant External Links for FAM228A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM228A Gene

mRNA expression in normal human tissues for FAM228A Gene

mRNA differential expression in normal tissues according to GTEx for FAM228A Gene

This gene is overexpressed in Testis (29.1).

Protein differential expression in normal tissues for FAM228A Gene

This gene is overexpressed in Plasma (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM228A Gene

SOURCE GeneReport for Unigene cluster for FAM228A Gene Hs.741736

genes like me logo Genes that share expressions with FAM228A: view

Expression partners for FAM228A Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM228A Gene

Orthologs for FAM228A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM228A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM228A 35
  • 72.16 (n)
  • 58.51 (a)
FAM228A 36
  • 32 (a)
(Mus musculus)
Mammalia Fam228a 35
  • 65.08 (n)
  • 53.97 (a)
Fam228a 36
  • 32 (a)
(Pan troglodytes)
Mammalia FAM228A 35
  • 99.03 (n)
  • 97.09 (a)
FAM228A 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Fam228a 35
  • 63.98 (n)
  • 42.74 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 6 (a)
-- 36
  • 13 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 15 (a)
(Gallus gallus)
Aves -- 36
  • 11 (a)
(Danio rerio)
Actinopterygii fam228a 36
  • 11 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 8 (a)
Species with no ortholog for FAM228A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM228A Gene

Gene Tree for FAM228A (if available)
Gene Tree for FAM228A (if available)

Paralogs for FAM228A Gene

(1) SIMAP similar genes for FAM228A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM228A: view

No data available for Paralogs for FAM228A Gene

Variants for FAM228A Gene

Sequence variations from dbSNP and Humsavar for FAM228A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs528246610 -- 24,187,177(+) CACAA(C/T)AAATA intron-variant
rs528422373 -- 24,179,245(+) AAAGA(A/G)CTTAA intron-variant
rs528547284 -- 24,186,787(+) GCGCC(C/T)ACCAC intron-variant
rs528599255 -- 24,186,830(+) GAAGG(G/T)GTTTC intron-variant
rs527997573 -- 24,181,825(+) TTATT(A/T)AAAAA intron-variant

Relevant External Links for FAM228A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM228A Gene

Disorders for FAM228A Gene

No disorders were found for FAM228A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM228A Gene

Publications for FAM228A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  3. A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosis. (PMID: 23509962) Greliche N. … TrAcgouAt D.A. (BMC Med. Genet. 2013) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM228A Gene

Sources for FAM228A Gene

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