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Aliases for FAM227B Gene

Aliases for FAM227B Gene

  • Family With Sequence Similarity 227, Member B 2 3
  • C15orf33 3 4
  • Chromosome 15 Open Reading Frame 33 2
  • Protein FAM227B 3

External Ids for FAM227B Gene

Previous Symbols for FAM227B Gene

  • C15orf33

Summaries for FAM227B Gene

GeneCards Summary for FAM227B Gene

FAM227B (Family With Sequence Similarity 227, Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM227B Gene

Genomics for FAM227B Gene

Genomic Location for FAM227B Gene

Start:
49,326,962 bp from pter
End:
49,620,931 bp from pter
Size:
293,970 bases
Orientation:
Minus strand

Genomic View for FAM227B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM227B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM227B Gene

No data available for Regulatory Elements for FAM227B Gene

Proteins for FAM227B Gene

  • Protein details for FAM227B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96M60-F227B_HUMAN
    Recommended name:
    Protein FAM227B
    Protein Accession:
    Q96M60
    Secondary Accessions:
    • Q86WS2

    Protein attributes for FAM227B Gene

    Size:
    508 amino acids
    Molecular mass:
    59956 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM227B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM227B Gene

Proteomics data for FAM227B Gene at MOPED

Post-translational modifications for FAM227B Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM227B Gene

Domains for FAM227B Gene

Protein Domains for FAM227B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F227B_HUMAN
Family:
  • Belongs to the FAM227 family.:
    • Q96M60
genes like me logo Genes that share domains with FAM227B: view

No data available for Gene Families for FAM227B Gene

Function for FAM227B Gene

miRNA for FAM227B Gene

miRTarBase miRNAs that target FAM227B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM227B Gene

Localization for FAM227B Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM227B Gene

Pathways for FAM227B Gene

SuperPathways for FAM227B Gene

No Data Available

Interacting Proteins for FAM227B Gene

Gene Ontology (GO) - Biological Process for FAM227B Gene

None

No data available for Pathways by source for FAM227B Gene

Transcripts for FAM227B Gene

Unigene Clusters for FAM227B Gene

Family with sequence similarity 227, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM227B Gene

No ASD Table

Relevant External Links for FAM227B Gene

GeneLoc Exon Structure for
FAM227B
ECgene alternative splicing isoforms for
FAM227B

Expression for FAM227B Gene

mRNA expression in normal human tissues for FAM227B Gene

SOURCE GeneReport for Unigene cluster for FAM227B Gene Hs.712959

genes like me logo Genes that share expressions with FAM227B: view

Orthologs for FAM227B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM227B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM227B 36
  • 98.81 (n)
  • 97.82 (a)
FAM227B 37
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM227B 36
  • 82.05 (n)
  • 73.9 (a)
dog
(Canis familiaris)
Mammalia FAM227B 36
  • 84.96 (n)
  • 77.25 (a)
FAM227B 37
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam227b 36
  • 74.27 (n)
  • 63.66 (a)
Fam227b 16
Fam227b 37
  • 54 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM227B 37
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM227B 37
  • 49 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam227b 36
  • 74.8 (n)
  • 64.79 (a)
lizard
(Anolis carolinensis)
Reptilia FAM227B 37
  • 37 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam227b 36
  • 54.31 (n)
  • 38.67 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 30 (a)
OneToOne
Species with no ortholog for FAM227B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM227B Gene

ENSEMBL:
Gene Tree for FAM227B (if available)
TreeFam:
Gene Tree for FAM227B (if available)

Paralogs for FAM227B Gene

Selected SIMAP similar genes for FAM227B Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with FAM227B: view

No data available for Paralogs for FAM227B Gene

Variants for FAM227B Gene

Sequence variations from dbSNP and Humsavar for FAM227B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs733097 -- 49,565,647(-) CACCA(A/G)TATTC intron-variant
rs753857 -- 49,565,701(-) GCCTT(A/G)TAAGG intron-variant
rs906419 -- 49,565,331(+) GAGCC(A/G)TGATT intron-variant
rs962710 -- 49,604,433(-) tacag(G/T)tataa intron-variant
rs965134 -- 49,522,109(+) gtcag(C/T)tcata intron-variant

Relevant External Links for FAM227B Gene

HapMap Linkage Disequilibrium report
FAM227B

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM227B Gene

Disorders for FAM227B Gene

No disorders were found for FAM227B Gene.

No data available for UniProtKB/Swiss-Prot for FAM227B Gene

Publications for FAM227B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. (PMID: 21565293) Teumer A. … VAPlzke H. (Am. J. Hum. Genet. 2011) 3
  5. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. (PMID: 23408906) Porcu E. … Naitza S. (PLoS Genet. 2013) 3

Products for FAM227B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM227B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM227B
    • Block miRNA regulation of FAM227B using miScript Target Protectors

    Sources for FAM227B Gene

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