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Aliases for FAM227A Gene

Aliases for FAM227A Gene

  • Family With Sequence Similarity 227, Member A 2 3

External Ids for FAM227A Gene

Summaries for FAM227A Gene

GeneCards Summary for FAM227A Gene

FAM227A (Family With Sequence Similarity 227, Member A) is a Protein Coding gene. An important paralog of this gene is FAM227B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM227A Gene

Genomics for FAM227A Gene

Genomic Location for FAM227A Gene

Start:
38,578,120 bp from pter
End:
38,656,629 bp from pter
Size:
78,510 bases
Orientation:
Minus strand

Genomic View for FAM227A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM227A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM227A Gene

No data available for Regulatory Elements for FAM227A Gene

Proteins for FAM227A Gene

  • Protein details for FAM227A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    F5H4B4-F227A_HUMAN
    Recommended name:
    Protein FAM227A
    Protein Accession:
    F5H4B4
    Secondary Accessions:
    • B0QY52
    • B7Z7C6
    • Q5TG08

    Protein attributes for FAM227A Gene

    Size:
    570 amino acids
    Molecular mass:
    66188 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM227A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM227A Gene

Proteomics data for FAM227A Gene at MOPED

Post-translational modifications for FAM227A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM227A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM227A Gene

Domains for FAM227A Gene

Protein Domains for FAM227A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F227A_HUMAN
Family:
  • Belongs to the FAM227 family.:
    • F5H4B4
genes like me logo Genes that share domains with FAM227A: view

No data available for Gene Families for FAM227A Gene

Function for FAM227A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM227A Gene

Localization for FAM227A Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM227A Gene

Pathways for FAM227A Gene

SuperPathways for FAM227A Gene

No Data Available

Interacting Proteins for FAM227A Gene

Gene Ontology (GO) - Biological Process for FAM227A Gene

None

No data available for Pathways by source for FAM227A Gene

Transcripts for FAM227A Gene

mRNA/cDNA for FAM227A Gene

(14) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(11) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM227A Gene

Family with sequence similarity 227, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM227A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b
SP1: -
SP2:
SP3: - -

Relevant External Links for FAM227A Gene

GeneLoc Exon Structure for
FAM227A
ECgene alternative splicing isoforms for
FAM227A

Expression for FAM227A Gene

mRNA expression in normal human tissues for FAM227A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM227A Gene

This gene is overexpressed in Pituitary (6.0) and Testis (5.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM227A Gene

SOURCE GeneReport for Unigene cluster for FAM227A Gene Hs.542707

genes like me logo Genes that share expressions with FAM227A: view

Orthologs for FAM227A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM227A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM227A 36
  • 98.89 (n)
  • 97.89 (a)
FAM227A 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM227A 36
  • 78.33 (n)
  • 65.74 (a)
FAM227A 37
  • 63 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM227A 37
  • 63 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam227a 36
  • 68.09 (n)
  • 55.93 (a)
Fam227a 16
Fam227a 37
  • 48 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM227A 37
  • 43 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM227A 37
  • 41 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam227a 36
  • 68.1 (n)
  • 53.92 (a)
lizard
(Anolis carolinensis)
Reptilia FAM227A 37
  • 25 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam227a 36
  • 47.7 (n)
  • 32.95 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 23 (a)
OneToOne
Species with no ortholog for FAM227A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM227A Gene

ENSEMBL:
Gene Tree for FAM227A (if available)
TreeFam:
Gene Tree for FAM227A (if available)

Paralogs for FAM227A Gene

Paralogs for FAM227A Gene

genes like me logo Genes that share paralogs with FAM227A: view

Variants for FAM227A Gene

Sequence variations from dbSNP and Humsavar for FAM227A Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs138689 -- 38,627,874(+) gctgg(-/G)attac intron-variant
rs738249 -- 38,641,974(+) gtgtg(C/T)gcgca intron-variant
rs760645 -- 38,636,265(+) AAGAC(C/T)GTTGC intron-variant
rs761334 -- 38,613,413(+) tatat(A/G)atata intron-variant
rs761335 -- 38,613,414(+) ATATG(A/T)TATAT intron-variant

Relevant External Links for FAM227A Gene

HapMap Linkage Disequilibrium report
FAM227A

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM227A Gene

Disorders for FAM227A Gene

No disorders were found for FAM227A Gene.

No data available for UniProtKB/Swiss-Prot for FAM227A Gene

Publications for FAM227A Gene

  1. The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I. … Wright H. (Nature 1999) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N. … Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for FAM227A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM227A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM227A
    • Block miRNA regulation of FAM227A using miScript Target Protectors

    Sources for FAM227A Gene

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