Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM221A Gene

Aliases for FAM221A Gene

  • Family With Sequence Similarity 221, Member A 2 3
  • C7orf46 3 4
  • Chromosome 7 Open Reading Frame 46 2
  • Uncharacterized Protein C7orf46 3
  • Protein FAM221A 3

External Ids for FAM221A Gene

Previous Symbols for FAM221A Gene

  • C7orf46

Summaries for FAM221A Gene

GeneCards Summary for FAM221A Gene

FAM221A (Family With Sequence Similarity 221, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM221A Gene

Genomics for FAM221A Gene

Genomic Location for FAM221A Gene

Start:
23,679,612 bp from pter
End:
23,703,249 bp from pter
Size:
23,638 bases
Orientation:
Plus strand

Genomic View for FAM221A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM221A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM221A Gene

No data available for Regulatory Elements for FAM221A Gene

Proteins for FAM221A Gene

  • Protein details for FAM221A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A4D161-F221A_HUMAN
    Recommended name:
    Protein FAM221A
    Protein Accession:
    A4D161
    Secondary Accessions:
    • Q05CG4
    • Q4G0Q7
    • Q6P519

    Protein attributes for FAM221A Gene

    Size:
    298 amino acids
    Molecular mass:
    33083 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH26000.1; Type=Frameshift; Positions=9; Evidence={ECO:0000305}; Sequence=AAH42034.1; Type=Frameshift; Positions=101; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM221A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM221A Gene

Proteomics data for FAM221A Gene at MOPED

Post-translational modifications for FAM221A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM221A Gene

Domains for FAM221A Gene

Protein Domains for FAM221A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F221A_HUMAN
Family:
  • Belongs to the FAM221 family.:
    • A4D161
genes like me logo Genes that share domains with FAM221A: view

No data available for Gene Families for FAM221A Gene

Function for FAM221A Gene

miRNA for FAM221A Gene

miRTarBase miRNAs that target FAM221A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM221A Gene

Localization for FAM221A Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM221A Gene

Pathways for FAM221A Gene

SuperPathways for FAM221A Gene

No Data Available

Interacting Proteins for FAM221A Gene

Gene Ontology (GO) - Biological Process for FAM221A Gene

None

No data available for Pathways by source for FAM221A Gene

Transcripts for FAM221A Gene

Unigene Clusters for FAM221A Gene

Family with sequence similarity 221, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM221A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9
SP1: -
SP2: - -
SP3: - -
SP4: - - -
SP5: - -
SP6:

Relevant External Links for FAM221A Gene

GeneLoc Exon Structure for
FAM221A
ECgene alternative splicing isoforms for
FAM221A

Expression for FAM221A Gene

mRNA expression in normal human tissues for FAM221A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM221A Gene

SOURCE GeneReport for Unigene cluster for FAM221A Gene Hs.592178

genes like me logo Genes that share expressions with FAM221A: view

Orthologs for FAM221A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM221A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM221A 36
  • 98.99 (n)
  • 97.99 (a)
FAM221A 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM221A 36
  • 88.26 (n)
  • 89.88 (a)
MGC134574 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM221A 36
  • 89.26 (n)
  • 87.92 (a)
FAM221A 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam221a 36
  • 84 (n)
  • 82.55 (a)
Fam221a 16
Fam221a 37
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM221A 37
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 78 (a)
OneToMany
-- 37
  • 76 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam221a 36
  • 83.13 (n)
  • 82.33 (a)
chicken
(Gallus gallus)
Aves C2H7ORF46 36
  • 73.1 (n)
  • 76.21 (a)
FAM221A 37
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM221A 37
  • 74 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10621 36
tropical clawed frog
(Silurana tropicalis)
Amphibia fam221a 36
  • 65.06 (n)
  • 67.01 (a)
Str.617 36
zebrafish
(Danio rerio)
Actinopterygii fam221a 36
  • 59.78 (n)
  • 57.28 (a)
fam221a 37
  • 56 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 55 (a)
OneToOne
Species with no ortholog for FAM221A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM221A Gene

ENSEMBL:
Gene Tree for FAM221A (if available)
TreeFam:
Gene Tree for FAM221A (if available)

Paralogs for FAM221A Gene

Selected SIMAP similar genes for FAM221A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM221A: view

No data available for Paralogs for FAM221A Gene

Variants for FAM221A Gene

Sequence variations from dbSNP and Humsavar for FAM221A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs723900 -- 23,683,679(+) CTCTT(A/G)TATAG intron-variant
rs1013879 -- 23,693,453(+) tgcct(A/G)ttcat intron-variant, nc-transcript-variant
rs1051576 -- 23,702,324(+) AAATG(C/T)CTATT utr-variant-3-prime, intron-variant, nc-transcript-variant
rs1055237 -- 23,679,958(-) GCACC(A/T)ATTCC upstream-variant-2KB, utr-variant-5-prime, nc-transcript-variant
rs1558308 -- 23,696,891(+) AGGAG(C/T)CCATA intron-variant

Relevant External Links for FAM221A Gene

HapMap Linkage Disequilibrium report
FAM221A

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM221A Gene

Disorders for FAM221A Gene

No disorders were found for FAM221A Gene.

No data available for UniProtKB/Swiss-Prot for FAM221A Gene

Publications for FAM221A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for FAM221A Gene

Sources for FAM221A Gene

Back to Top

Content