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Aliases for FAM219B Gene

Aliases for FAM219B Gene

  • Family With Sequence Similarity 219, Member B 2 3
  • C15orf17 3 4
  • Chromosome 15 Open Reading Frame 17 2
  • Uncharacterized Protein C15orf17 3
  • Protein FAM219B 3

External Ids for FAM219B Gene

Previous Symbols for FAM219B Gene

  • C15orf17

Summaries for FAM219B Gene

GeneCards Summary for FAM219B Gene

FAM219B (Family With Sequence Similarity 219, Member B) is a Protein Coding gene. An important paralog of this gene is FAM219A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM219B Gene

Genomics for FAM219B Gene

Genomic Location for FAM219B Gene

Start:
74,899,987 bp from pter
End:
74,907,191 bp from pter
Size:
7,205 bases
Orientation:
Minus strand

Genomic View for FAM219B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM219B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM219B Gene

No data available for Regulatory Elements for FAM219B Gene

Proteins for FAM219B Gene

  • Protein details for FAM219B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5XKK7-F219B_HUMAN
    Recommended name:
    Protein FAM219B
    Protein Accession:
    Q5XKK7
    Secondary Accessions:
    • A8K4Q5
    • B4DK57
    • Q9NXY0

    Protein attributes for FAM219B Gene

    Size:
    198 amino acids
    Molecular mass:
    21103 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM219B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM219B Gene

Proteomics data for FAM219B Gene at MOPED

Post-translational modifications for FAM219B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM219B Gene

Domains for FAM219B Gene

Protein Domains for FAM219B Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F219B_HUMAN
Family:
  • Belongs to the FAM219 family.:
    • Q5XKK7
genes like me logo Genes that share domains with FAM219B: view

No data available for Gene Families for FAM219B Gene

Function for FAM219B Gene

Phenotypes for FAM219B Gene

GenomeRNAi human phenotypes for FAM219B:
genes like me logo Genes that share phenotypes with FAM219B: view

miRNA for FAM219B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM219B Gene

Localization for FAM219B Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM219B Gene

Pathways for FAM219B Gene

SuperPathways for FAM219B Gene

No Data Available

Interacting Proteins for FAM219B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000350260%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000350260 Q5XKK7-F219B_HUMAN for FAM219B Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM219B Gene

None

No data available for Pathways by source for FAM219B Gene

Transcripts for FAM219B Gene

Unigene Clusters for FAM219B Gene

Family with sequence similarity 219, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM219B Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g · 7h · 7i · 7j · 7k · 7l ^
SP1: - - - - - - - -
SP2: - - - - - - - -
SP3: -
SP4: - -
SP5: - - -
SP6: - - -
SP7: - - -
SP8: - - - - - - - - - -
SP9: -
SP10: - - - - -
SP11: - - - - -
SP12: -
SP13: - - -
SP14: - -
SP15: -
SP16: - - - - - -

ExUns: 8a · 8b · 8c ^ 9
SP1: - -
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:

Relevant External Links for FAM219B Gene

GeneLoc Exon Structure for
FAM219B
ECgene alternative splicing isoforms for
FAM219B

Expression for FAM219B Gene

mRNA expression in normal human tissues for FAM219B Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM219B Gene

SOURCE GeneReport for Unigene cluster for FAM219B Gene Hs.367690

genes like me logo Genes that share expressions with FAM219B: view

Orthologs for FAM219B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM219B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM219B 36
  • 92.15 (n)
  • 88.48 (a)
FAM219B 37
  • 86 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C21H15orf17 36
  • 88.31 (n)
  • 86.91 (a)
FAM219B 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C30H15orf17 36
  • 89.95 (n)
  • 91.1 (a)
FAM219B 37
  • 32 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam219b 36
  • 86.13 (n)
  • 83.76 (a)
Fam219b 16
Fam219b 37
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM219B 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM219B 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam219b 36
  • 81.63 (n)
  • 75.59 (a)
chicken
(Gallus gallus)
Aves FAM219B 36
  • 77.13 (n)
  • 75.21 (a)
lizard
(Anolis carolinensis)
Reptilia FAM219B 37
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam219b 36
  • 66.9 (n)
  • 70.83 (a)
Str.3563 36
zebrafish
(Danio rerio)
Actinopterygii fam219b 36
  • 60.58 (n)
  • 53.28 (a)
fam219b 37
  • 47 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea CSA.170 37
  • 42 (a)
OneToMany
Species with no ortholog for FAM219B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM219B Gene

ENSEMBL:
Gene Tree for FAM219B (if available)
TreeFam:
Gene Tree for FAM219B (if available)

Paralogs for FAM219B Gene

Paralogs for FAM219B Gene

Selected SIMAP similar genes for FAM219B Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with FAM219B: view

Variants for FAM219B Gene

Sequence variations from dbSNP and Humsavar for FAM219B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1127796 -- 74,900,663(-) AGAAC(A/G)TCTCC utr-variant-3-prime, intron-variant, nc-transcript-variant
rs1127797 -- 74,900,636(-) CCATC(G/T)GCAGA utr-variant-3-prime, intron-variant, nc-transcript-variant
rs1128350 -- 74,901,788(-) AGCCT(G/T)CAGTT utr-variant-3-prime, intron-variant, nc-transcript-variant
rs3935818 -- 74,902,087(+) ACTCA(C/T)TTTAT utr-variant-3-prime, intron-variant, nc-transcript-variant
rs4886634 -- 74,903,110(+) CCCAG(A/C)CTAGT intron-variant

Relevant External Links for FAM219B Gene

HapMap Linkage Disequilibrium report
FAM219B

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM219B Gene

Disorders for FAM219B Gene

No disorders were found for FAM219B Gene.

No data available for UniProtKB/Swiss-Prot for FAM219B Gene

Publications for FAM219B Gene

  1. Characterization of long cDNA clones from human adult spleen. (PMID: 11214971) Hattori A. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for FAM219B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM219B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM219B
    • Block miRNA regulation of FAM219B using miScript Target Protectors

    Sources for FAM219B Gene

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