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Aliases for FAM219B Gene

Aliases for FAM219B Gene

  • Family With Sequence Similarity 219, Member B 2 3
  • C15orf17 3 4
  • Chromosome 15 Open Reading Frame 17 2
  • Uncharacterized Protein C15orf17 3
  • Protein FAM219B 3

External Ids for FAM219B Gene

Previous HGNC Symbols for FAM219B Gene

  • C15orf17

Previous GeneCards Identifiers for FAM219B Gene

  • GC15M075193

Summaries for FAM219B Gene

GeneCards Summary for FAM219B Gene

FAM219B (Family With Sequence Similarity 219, Member B) is a Protein Coding gene. An important paralog of this gene is FAM219A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM219B Gene

Genomics for FAM219B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM219B Gene

74,899,987 bp from pter
74,907,191 bp from pter
7,205 bases
Minus strand

Genomic View for FAM219B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM219B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM219B Gene

No data available for Regulatory Elements for FAM219B Gene

Proteins for FAM219B Gene

  • Protein details for FAM219B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM219B
    Protein Accession:
    Secondary Accessions:
    • A8K4Q5
    • B4DK57
    • Q9NXY0

    Protein attributes for FAM219B Gene

    198 amino acids
    Molecular mass:
    21103 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM219B Gene


neXtProt entry for FAM219B Gene

Proteomics data for FAM219B Gene at MOPED

Post-translational modifications for FAM219B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM219B Gene

Domains for FAM219B Gene

Protein Domains for FAM219B Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM219 family.
  • Belongs to the FAM219 family.
genes like me logo Genes that share domains with FAM219B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM219B Gene

Function for FAM219B Gene

Phenotypes for FAM219B Gene

GenomeRNAi human phenotypes for FAM219B:
genes like me logo Genes that share phenotypes with FAM219B: view

Animal Model Products

CRISPR Products

miRNA for FAM219B Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM219B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM219B Gene

Localization for FAM219B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM219B Gene

Pathways for FAM219B Gene

SuperPathways for FAM219B Gene

No Data Available

Interacting Proteins for FAM219B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000350260 Q5XKK7-F219B_HUMAN for FAM219B Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM219B Gene


No data available for Pathways by source for FAM219B Gene

Transcripts for FAM219B Gene

Unigene Clusters for FAM219B Gene

Family with sequence similarity 219, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM219B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM219B Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f · 7g · 7h · 7i · 7j · 7k · 7l ^
SP1: - - - - - - - -
SP2: - - - - - - - -
SP3: -
SP4: - -
SP5: - - -
SP6: - - -
SP7: - - -
SP8: - - - - - - - - - -
SP9: -
SP10: - - - - -
SP11: - - - - -
SP12: -
SP13: - - -
SP14: - -
SP15: -
SP16: - - - - - -

ExUns: 8a · 8b · 8c ^ 9
SP1: - -

Relevant External Links for FAM219B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM219B Gene

mRNA expression in normal human tissues for FAM219B Gene

Protein differential expression in normal tissues for FAM219B Gene

This gene is overexpressed in Liver (55.9), Monocytes (6.5), and Pancreatic juice (6.4).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM219B Gene

SOURCE GeneReport for Unigene cluster for FAM219B Gene Hs.367690

genes like me logo Genes that share expressions with FAM219B: view

Expression partners for FAM219B Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM219B Gene

Orthologs for FAM219B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM219B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C21H15orf17 35
  • 88.31 (n)
  • 86.91 (a)
FAM219B 36
  • 87 (a)
(Canis familiaris)
Mammalia C30H15orf17 35
  • 89.95 (n)
  • 91.1 (a)
FAM219B 36
  • 32 (a)
(Mus musculus)
Mammalia Fam219b 35
  • 86.13 (n)
  • 83.76 (a)
Fam219b 16
Fam219b 36
  • 80 (a)
(Pan troglodytes)
Mammalia FAM219B 35
  • 92.15 (n)
  • 88.48 (a)
FAM219B 36
  • 86 (a)
(Rattus norvegicus)
Mammalia Fam219b 35
  • 81.63 (n)
  • 75.59 (a)
(Monodelphis domestica)
Mammalia FAM219B 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia FAM219B 36
  • 65 (a)
(Gallus gallus)
Aves FAM219B 35
  • 77.13 (n)
  • 75.21 (a)
(Anolis carolinensis)
Reptilia FAM219B 36
  • 71 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam219b 35
  • 66.9 (n)
  • 70.83 (a)
Str.3563 35
(Danio rerio)
Actinopterygii fam219b 35
  • 60.58 (n)
  • 53.28 (a)
fam219b 36
  • 47 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.170 36
  • 42 (a)
Species with no ortholog for FAM219B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM219B Gene

Gene Tree for FAM219B (if available)
Gene Tree for FAM219B (if available)

Paralogs for FAM219B Gene

Paralogs for FAM219B Gene

(2) SIMAP similar genes for FAM219B Gene using alignment to 8 proteins:

genes like me logo Genes that share paralogs with FAM219B: view

Variants for FAM219B Gene

Sequence variations from dbSNP and Humsavar for FAM219B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs1127796 -- 74,900,663(-) AGAAC(A/G)TCTCC utr-variant-3-prime, intron-variant, nc-transcript-variant
rs1127797 -- 74,900,636(-) CCATC(G/T)GCAGA utr-variant-3-prime, intron-variant, nc-transcript-variant
rs1128350 -- 74,901,788(-) AGCCT(G/T)CAGTT utr-variant-3-prime, intron-variant, nc-transcript-variant
rs3935818 -- 74,902,087(+) ACTCA(C/T)TTTAT utr-variant-3-prime, intron-variant, nc-transcript-variant
rs4886634 -- 74,903,110(+) CCCAG(A/C)CTAGT intron-variant

Relevant External Links for FAM219B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM219B Gene

Disorders for FAM219B Gene

No disorders were found for FAM219B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM219B Gene

Publications for FAM219B Gene

  1. Characterization of long cDNA clones from human adult spleen. (PMID: 11214971) Hattori A. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for FAM219B Gene

Sources for FAM219B Gene

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