Aliases for FAM219A Gene
Aliases for FAM219A Gene
External Ids for FAM219A Gene
- HGNC: 19920
- Entrez Gene: 203259
- Ensembl: ENSG00000164970
- UniProtKB: Q8IW50
Previous HGNC Symbols for FAM219A Gene
- C9orf25
Summaries for FAM219A Gene
-
The protein encoded by this gene has homologs that have been identified in mouse, macaque, etc organisms. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for FAM219A Gene
FAM219A (Family With Sequence Similarity 219 Member A) is a Protein Coding gene. An important paralog of this gene is FAM219B.
No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM219A Gene
Genomics for FAM219A Gene
Regulatory Elements for FAM219A Gene
Enhancers for FAM219A Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around FAM219A on UCSC Golden Path with GeneCards custom track
Promoters for FAM219A Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around FAM219A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FAM219A Gene
- Chromosome:
- 9
- Start:
- 34,398,184 bp from pter
- End:
- 34,458,610 bp from pter
- Size:
- 60,427 bases
- Orientation:
- Minus strand
Genomic View for FAM219A Gene
Genes around FAM219A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9p13.3 by Ensembl
- 9p13.3 by Entrez Gene
- 9p11.2 by HGNC
FAM219A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM219A Gene
Proteins for FAM219A Gene
-
Protein details for FAM219A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8IW50-F219A_HUMAN
- Recommended name:
- Protein FAM219A
- Protein Accession:
- Q8IW50
- A2A364
- B4DFE1
- B4DSR8
- Q5T590
- Q5T591
- Q5T592
- Q5T594
- Q5T595
- Q8TAZ8
Protein attributes for FAM219A Gene
- Size:
- 185 amino acids
- Molecular mass:
- 20400 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=CAI13147.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13149.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13151.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13152.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13153.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15969.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15970.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15972.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15973.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15974.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for FAM219A Gene
Post-translational modifications for FAM219A Gene
Other Protein References for FAM219A Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAM219A
- Novus Biologicals Antibodies for FAM219A
- Abcam antibodies for C9orf25
- antibodies-online Antibodies for FAM219A: See all 20
- GeneTex FAM219A antibody for FAM219A
-
Santa Cruz Biotechnology (SCBT) Antibodies for FAM219A
Protein Products
-
OriGene Purified Proteins for FAM219A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM219A
- Origene Custom Protein Services for FAM219A
- antibodies-online Proteins for FAM219A: See all 3
- Search antibodies-online for peptides
- Search GeneTex for Proteins for FAM219A
Assay Products
No data available for DME Specific Peptides for FAM219A Gene
Domains & Families for FAM219A Gene
Graphical View of Domain Structure for InterPro Entry
Q8IW50- Family:
-
- Belongs to the FAM219 family.
No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM219A Gene
Function for FAM219A Gene
Phenotypes for FAM219A Gene
- GenomeRNAi human phenotypes for FAM219A:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Search ViGene Biosciences for FAM219A
CRISPR Products
-
OriGene CRISPR knockouts for FAM219A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM219A
- GenScript: Design CRISPR guide RNA sequences for FAM219A
miRNA for FAM219A Gene
- miRTarBase miRNAs that target FAM219A
miRNA Products
- Search ViGene Biosciences for FAM219A
Inhibitory RNA Products
Clone Products
- OriGene clones in human for FAM219A
- OriGene ORF clones in human,mouse,rat for FAM219A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM219A Gene
Localization for FAM219A Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| golgi apparatus | 2 |
| extracellular | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM219A Gene
Pathways & Interactions for FAM219A Gene
More details on SuperPathways for FAM219A
No Data Available
Interacting Proteins for FAM219A Gene
Selected Interacting proteins:
Q8IW50-F219A_HUMAN
ENSP00000392452
for FAM219A Gene via
MINT
STRING
I2D
No data available for Pathways by source and SIGNOR curated interactions for FAM219A Gene
Transcripts for FAM219A Gene
mRNA/cDNA for FAM219A Gene
- (14) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (198) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM219A Gene
- Family with sequence similarity 219, member A:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for FAM219A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM219A
- GenScript: Design CRISPR guide RNA sequences for FAM219A
miRNA Products
- Search ViGene Biosciences for FAM219A
Inhibitory RNA Products
Clone Products
- OriGene clones in human for FAM219A
- OriGene ORF clones in human,mouse,rat for FAM219A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||
| SP6: | - |
Expression for FAM219A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM219A Gene
SOURCE GeneReport for Unigene cluster for FAM219A Gene Hs.493771
Primer Products
-
OriGene qPCR primer pairs for FAM219A
-
OriGene qPCR primer pairs and template standards for FAM219A
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM219A Gene
Orthologs for FAM219A Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | FAM219A 35 |
|
||
| FAM219A 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | FAM219A 35 |
|
||
| FAM219A 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Fam219a 35 |
|
||
| Fam219a 16 |
|
||||
| Fam219a 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | FAM219A 35 |
|
||
| FAM219A 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Fam219a 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM219A 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM219A 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CZH9ORF25 35 |
|
||
| FAM219A 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | FAM219A 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100485411 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam219aa 35 |
|
||
| fam219aa 36 |
|
OneToMany | |||
| fam219ab 36 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.170 36 |
|
OneToMany |
- Species with no ortholog for FAM219A:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM219A Gene
(1) SIMAP similar genes for FAM219A Gene using alignment to 3 proteins:
Variants for FAM219A Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs876222 | -- | 34,414,086(+) | TAAGT(C/G)CTCAT | intron-variant | |
| rs946847 | -- | 34,408,206(-) | ACTTG(A/C)AGCAT | intron-variant, upstream-variant-2KB | |
| rs1075744 | -- | 34,444,243(+) | TCCCA(C/G)CAGAG | intron-variant | |
| rs1111069 | -- | 34,445,176(-) | GTGGA(A/G)AGGAG | intron-variant | |
| rs1126119 | -- | 34,446,721(-) | AGAAA(C/G)CATTT | intron-variant |
Residual Variation Intolerance Score:
47.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.04;
0.82% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM219A Gene
Disorders for FAM219A Gene
Relevant External Links for FAM219A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM219A
No disorders were found for FAM219A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM219A Gene
Publications for FAM219A Gene
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 67
- Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 2 3
- A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3
- BioID-based Identification of Skp Cullin F-box (SCF)I^-TrCP1/2 E3 Ligase Substrates. (PMID: 25900982) Coyaud E. … Raught B. (Mol. Cell Proteomics 2015) 3
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
Products for FAM219A Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for FAM219A
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM219A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM219A
- Origene Custom Protein Services for FAM219A
- Origene siRNA, mouse_rna, rat_shrna, shRNA, and RNAi products in human, mouse, rat for FAM219A
- Browse OriGene Inhibitory RNA Products For FAM219A
- OriGene qPCR primer pairs for FAM219A
- OriGene qPCR primer pairs and template standards for FAM219A
- OriGene CRISPR knockouts for FAM219A
- OriGene clones in human for FAM219A
- OriGene ORF clones in human,mouse,rat for FAM219A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM219A
- GenScript Custom Assay Services for FAM219A
- GenScript Custom overexpressing Cell Line Services for FAM219A
- GenScript: Design CRISPR guide RNA sequences for FAM219A
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM219A
- Novus Biologicals Antibodies for FAM219A
- Novus Biologicals proteins and lysates for FAM219A
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for FAM219A: See all 20
- Search antibodies-online for kits
- antibodies-online Proteins for FAM219A: See all 3
- Search antibodies-online for peptides
- GeneTex FAM219A antibody for FAM219A
- Search GeneTex for Proteins for FAM219A
- Search ViGene Biosciences for FAM219A
- Search ViGene Biosciences for FAM219A
- Santa Cruz Biotechnology (SCBT) Antibodies for FAM219A
- Search Santa Cruz Biotechnology (SCBT) for FAM219A siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FAM219A
Sources for FAM219A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon