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Aliases for FAM219A Gene

Aliases for FAM219A Gene

  • Family With Sequence Similarity 219, Member A 2 3
  • C9orf25 3 4
  • Chromosome 9 Open Reading Frame 25 2
  • Uncharacterized Protein C9orf25 3
  • Protein FAM219A 3
  • BA573M23.5 3

External Ids for FAM219A Gene

Previous HGNC Symbols for FAM219A Gene

  • C9orf25

Summaries for FAM219A Gene

Entrez Gene Summary for FAM219A Gene

  • The protein encoded by this gene has homologs that have been identified in mouse, macaque, etc organisms. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

GeneCards Summary for FAM219A Gene

FAM219A (Family With Sequence Similarity 219, Member A) is a Protein Coding gene. An important paralog of this gene is FAM219B.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM219A Gene

Genomics for FAM219A Gene

Genomic Location for FAM219A Gene

Start:
34,398,184 bp from pter
End:
34,458,570 bp from pter
Size:
60,387 bases
Orientation:
Minus strand

Genomic View for FAM219A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM219A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM219A Gene

No data available for Regulatory Elements for FAM219A Gene

Proteins for FAM219A Gene

  • Protein details for FAM219A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IW50-F219A_HUMAN
    Recommended name:
    Protein FAM219A
    Protein Accession:
    Q8IW50
    Secondary Accessions:
    • A2A364
    • B4DFE1
    • B4DSR8
    • Q5T590
    • Q5T591
    • Q5T592
    • Q5T594
    • Q5T595
    • Q8TAZ8

    Protein attributes for FAM219A Gene

    Size:
    185 amino acids
    Molecular mass:
    20400 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI13147.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13149.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13151.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13152.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI13153.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15969.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15970.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15972.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15973.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI15974.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM219A Gene

neXtProt entry for FAM219A Gene

Proteomics data for FAM219A Gene at MOPED

Post-translational modifications for FAM219A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM219A Gene

Domains for FAM219A Gene

Protein Domains for FAM219A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8IW50

UniProtKB/Swiss-Prot:

F219A_HUMAN :
  • Q8IW50
Family:
  • Belongs to the FAM219 family.
genes like me logo Genes that share domains with FAM219A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM219A Gene

Function for FAM219A Gene

Phenotypes for FAM219A Gene

GenomeRNAi human phenotypes for FAM219A:
genes like me logo Genes that share phenotypes with FAM219A: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM219A Gene

Localization for FAM219A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM219A Gene

Pathways for FAM219A Gene

SuperPathways for FAM219A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM219A Gene

None

No data available for Pathways by source for FAM219A Gene

Transcripts for FAM219A Gene

Unigene Clusters for FAM219A Gene

Family with sequence similarity 219, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM219A Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1: - - - -
SP2: - - - -
SP3: - - -
SP4: - -
SP5: -
SP6: -

Relevant External Links for FAM219A Gene

GeneLoc Exon Structure for
FAM219A
ECgene alternative splicing isoforms for
FAM219A

Expression for FAM219A Gene

mRNA expression in normal human tissues for FAM219A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM219A Gene

SOURCE GeneReport for Unigene cluster for FAM219A Gene Hs.493771

genes like me logo Genes that share expressions with FAM219A: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM219A Gene

Orthologs for FAM219A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM219A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM219A 35
  • 99.46 (n)
  • 99.46 (a)
FAM219A 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM219A 35
  • 97.12 (n)
  • 100 (a)
FAM219A 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM219A 35
  • 96.4 (n)
  • 100 (a)
FAM219A 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam219a 35
  • 93.85 (n)
  • 99.4 (a)
Fam219a 16
Fam219a 36
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM219A 36
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM219A 36
  • 78 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam219a 35
  • 92.57 (n)
  • 98.73 (a)
chicken
(Gallus gallus)
Aves CZH9ORF25 35
  • 84.86 (n)
  • 95.14 (a)
FAM219A 36
  • 99 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM219A 36
  • 95 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100485411 35
  • 84.85 (n)
  • 96.21 (a)
zebrafish
(Danio rerio)
Actinopterygii fam219aa 35
  • 77.66 (n)
  • 87.57 (a)
fam219aa 36
  • 87 (a)
OneToMany
fam219ab 36
  • 83 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.170 36
  • 44 (a)
OneToMany
Species with no ortholog for FAM219A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM219A Gene

ENSEMBL:
Gene Tree for FAM219A (if available)
TreeFam:
Gene Tree for FAM219A (if available)

Paralogs for FAM219A Gene

Paralogs for FAM219A Gene

Selected SIMAP similar genes for FAM219A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM219A: view

Variants for FAM219A Gene

Sequence variations from dbSNP and Humsavar for FAM219A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs876222 -- 34,414,086(+) TAAGT(C/G)CTCAT intron-variant
rs946847 -- 34,408,206(-) ACTTG(A/C)AGCAT intron-variant, upstream-variant-2KB
rs1075744 -- 34,444,243(+) TCCCA(C/G)CAGAG intron-variant
rs1111069 -- 34,445,176(-) GTGGA(A/G)AGGAG intron-variant
rs1126119 -- 34,446,721(-) AGAAA(C/G)CATTT intron-variant

Relevant External Links for FAM219A Gene

HapMap Linkage Disequilibrium report
FAM219A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM219A Gene

Disorders for FAM219A Gene

No disorders were found for FAM219A Gene.

No data available for UniProtKB/Swiss-Prot for FAM219A Gene

Publications for FAM219A Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. A "double adaptor" method for improved shotgun library construction. (PMID: 8619474) Andersson B. … Gibbs R.A. (Anal. Biochem. 1996) 2 3

Products for FAM219A Gene

Sources for FAM219A Gene

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