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Aliases for FAM217B Gene

Aliases for FAM217B Gene

  • Family With Sequence Similarity 217, Member B 2 3
  • C20orf177 3 4
  • Chromosome 20 Open Reading Frame 177 2
  • Uncharacterized Protein C20orf177 3
  • Protein FAM217B 3
  • DJ551D2.5 3

External Ids for FAM217B Gene

Previous HGNC Symbols for FAM217B Gene

  • C20orf177

Previous GeneCards Identifiers for FAM217B Gene

  • GC20P058509

Summaries for FAM217B Gene

GeneCards Summary for FAM217B Gene

FAM217B (Family With Sequence Similarity 217, Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM217B Gene

Genomics for FAM217B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM217B Gene

59,933,764 bp from pter
59,948,680 bp from pter
14,917 bases
Plus strand

Genomic View for FAM217B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM217B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM217B Gene

No data available for Regulatory Elements for FAM217B Gene

Proteins for FAM217B Gene

  • Protein details for FAM217B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM217B
    Protein Accession:
    Secondary Accessions:
    • B3KWH1
    • Q9NTA3

    Protein attributes for FAM217B Gene

    383 amino acids
    Molecular mass:
    42052 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM217B Gene

Proteomics data for FAM217B Gene at MOPED

Post-translational modifications for FAM217B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM217B Gene

No data available for DME Specific Peptides for FAM217B Gene

Domains for FAM217B Gene

Protein Domains for FAM217B Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9NTX9
  • Belongs to the FAM217 family.
genes like me logo Genes that share domains with FAM217B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM217B Gene

Function for FAM217B Gene

Phenotypes for FAM217B Gene

GenomeRNAi human phenotypes for FAM217B:
genes like me logo Genes that share phenotypes with FAM217B: view

Animal Model Products

miRNA for FAM217B Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM217B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM217B Gene

Localization for FAM217B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM217B Gene

Pathways for FAM217B Gene

SuperPathways for FAM217B Gene

No Data Available

Interacting Proteins for FAM217B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000351040 for FAM217B Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM217B Gene


No data available for Pathways by source for FAM217B Gene

Transcripts for FAM217B Gene

Unigene Clusters for FAM217B Gene

Family with sequence similarity 217, member B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM217B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM217B Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6
SP1: - -
SP2: - - - -
SP3: -

Relevant External Links for FAM217B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM217B Gene

mRNA expression in normal human tissues for FAM217B Gene

mRNA differential expression in normal tissues according to GTEx for FAM217B Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (4.5).

SOURCE GeneReport for Unigene cluster for FAM217B Gene Hs.54973

genes like me logo Genes that share expressions with FAM217B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for FAM217B Gene

Orthologs for FAM217B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM217B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM217B 35
  • 74.6 (n)
  • 69.58 (a)
FAM217B 36
  • 69 (a)
(Canis familiaris)
Mammalia C24H20orf177 35
  • 63.59 (n)
  • 56.42 (a)
FAM217B 36
  • 53 (a)
(Mus musculus)
Mammalia Fam217b 35
  • 71.43 (n)
  • 63.23 (a)
Fam217b 16
Fam217b 36
  • 63 (a)
(Pan troglodytes)
Mammalia FAM217B 35
  • 99.83 (n)
  • 100 (a)
FAM217B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam217b 35
  • 69.83 (n)
  • 61.74 (a)
(Monodelphis domestica)
Mammalia FAM217B 36
  • 42 (a)
(Ornithorhynchus anatinus)
Mammalia FAM217B 36
  • 40 (a)
(Gallus gallus)
Aves C20H20ORF177 35
  • 59.89 (n)
  • 49.68 (a)
FAM217B 36
  • 46 (a)
(Anolis carolinensis)
Reptilia FAM217B 36
  • 43 (a)
(Danio rerio)
Actinopterygii fam217b 36
  • 17 (a)
FAM217B (2 of 2) 36
  • 17 (a)
Species with no ortholog for FAM217B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM217B Gene

Gene Tree for FAM217B (if available)
Gene Tree for FAM217B (if available)

Paralogs for FAM217B Gene

Selected SIMAP similar genes for FAM217B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM217B: view

No data available for Paralogs for FAM217B Gene

Variants for FAM217B Gene

Sequence variations from dbSNP and Humsavar for FAM217B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs194971 -- 59,946,771(+) AAGTA(G/T)TACTT utr-variant-3-prime
rs194972 -- 59,947,281(-) gatcc(A/G)cctgc utr-variant-3-prime
rs194973 -- 59,948,049(+) AAAAA(A/G)AAAAA utr-variant-3-prime
rs3928738 -- 59,936,231(-) TATAT(A/G)ACGT intron-variant
rs4812141 -- 59,943,702(+) TGGAA(A/C)CTGTG intron-variant

Relevant External Links for FAM217B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM217B Gene

Disorders for FAM217B Gene

No disorders were found for FAM217B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM217B Gene

Publications for FAM217B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FAM217B Gene

Sources for FAM217B Gene

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