FAM217A Gene
protein-coding GIFtS: 34
GCID: GC06M004050
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family with sequence similarity 217, member A(Previous name: chromosome 6 open reading frame 146 )
(Previous symbol: C6orf146)
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Aliases
for FAM217A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 217, Member A1 2 | | C6orf1461 2 3 | | MGC435811 | | Chromosome 6 Open Reading Frame 1461 | | Protein FAM217A2 | | Uncharacterized Protein C6orf1462 |
Export aliases for FAM217A gene to outside databases |
Summaries
for FAM217A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM217A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM217A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM217A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM217A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p25.2 Ensembl cytogenetic band: 6p25.2 HGNC cytogenetic band: 6p25.1FAM217A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M004050: view genomic region
(about GC identifiers)
Start:
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4,049,668 bp from pter |
End:
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4,087,578 bp from pter |
Size:
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37,911 bases |
Orientation:
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minus strand |
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Proteins
for FAM217A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F217A_HUMAN, Q8IXS0 (See
protein sequence)Recommended Name: Protein FAM217A Size: 508 amino acids; 57420 Da
Sequence caution: Sequence=CAI42122.1; Type=Erroneous gene model prediction;
Secondary accessions: Q5JYK1Explore the universe of human proteins at neXtProt for FAM217A: NX_Q8IXS0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IXS0
FAM217A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_775834.2
ENSEMBL proteins: ENSP00000274673 ENSP00000417363 ENSP00000418500 ENSP00000418339
Human Recombinant Protein Products:
FAM217A Antibody Products:
Assay Products for FAM217A: |
Protein
Domains /
Families
for FAM217A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8IXS0 UniProtKB/Swiss-Prot: F217A_HUMAN, Q8IXS0Similarity: Belongs to the FAM217 family |
Function
for FAM217A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM217A | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM217A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM217A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM217A |
|
Pathways & Interactions
for FAM217A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM217A
|
Drugs & Compounds
for FAM217A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM217A
Search CenterWatch for drugs/clinical trials and news about FAM217A / F217A
|
Transcripts
for FAM217A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM217A gene: NM_173563.2 Unigene Cluster for FAM217A: Family with sequence similarity 217, member A Hs.657342 [show with all ESTs]Unigene Representative Sequence: NM_1735638 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000463904 ENST00000469157(uc010jnq.1) ENST00000274673(uc003mvx.3)
ENST00000380188(uc003mvy.3) ENST00000470599 ENST00000498677 ENST00000492651
ENST00000478714
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM217A | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM217A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM217A |
Additional cDNA sequence: AK097426.1 BC039349.1 3 DOTS entries: DT.452723 DT.100019820 DT.97803041 18 AceView cDNA sequences: AA928518 BC040899 BM553243 BM559565 Z21377 AA609005 AK097426 BC039349 NM_173563 AA770470 AA723684 AA934994 AI206750 BX090628 AI206756 BI462239 BI462483 AW510632
GeneLoc Exon Structure
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Expression
for FAM217A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM217A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGTGTTTCA
About this image
See FAM217A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM217A
SOURCE GeneReport for Unigene cluster: Hs.657342
SABiosciences Custom PCR Arrays for FAM217A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM217A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM217A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM217A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM217A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM217A |
Orthologs
for FAM217A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM217A gene from 2/6 species (see all 6) About this table
ENSEMBL Gene Tree for FAM217A (if available)
TreeFam Gene Tree for FAM217A (if available) |
Paralogs
for FAM217A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM217A gene
FAM217A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FAM217A
PGOHUM00000236352
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Genomic Variants
for FAM217A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM217A (4049668 - 4087578 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM217A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM217A |
|
Disorders
/ Diseases
for FAM217A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM217A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM217A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM217A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM217A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM217A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM217A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM217A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM217A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM217A gene:
Search GeneIP for patents involving FAM217A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM217A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM217A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM217A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM217A | | | OriGene Protein Over-expression Lysate for FAM217A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM217A | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM217A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM217A | | OriGene Custom Protein Services for FAM217A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM217A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM217A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM217A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM217A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM217A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM217A |
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| | | | Search Tocris compounds for FAM217A |
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 | | | FAM217A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM217A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM217A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM217A |
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