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Aliases for FAM216A Gene

Aliases for FAM216A Gene

  • Family With Sequence Similarity 216, Member A 2 3
  • C12orf24 3 4
  • Chromosome 12 Open Reading Frame 24 2
  • Protein Predicted By Clone 23733 3
  • Uncharacterized Protein C12orf24 3
  • Protein FAM216A 3
  • HSU79274 3

External Ids for FAM216A Gene

Previous HGNC Symbols for FAM216A Gene

  • C12orf24

Previous GeneCards Identifiers for FAM216A Gene

  • GC12P110907

Summaries for FAM216A Gene

GeneCards Summary for FAM216A Gene

FAM216A (Family With Sequence Similarity 216, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM216A Gene

Genomics for FAM216A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM216A Gene

110,468,364 bp from pter
110,490,387 bp from pter
22,024 bases
Plus strand

Genomic View for FAM216A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM216A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM216A Gene

No data available for Regulatory Elements for FAM216A Gene

Proteins for FAM216A Gene

  • Protein details for FAM216A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM216A
    Protein Accession:
    Secondary Accessions:
    • A6NH30
    • Q99776

    Protein attributes for FAM216A Gene

    273 amino acids
    Molecular mass:
    30792 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM216A Gene

Proteomics data for FAM216A Gene at MOPED

Post-translational modifications for FAM216A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM216A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM216A Gene

Domains for FAM216A Gene

Protein Domains for FAM216A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM216 family.
  • Belongs to the FAM216 family.
genes like me logo Genes that share domains with FAM216A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM216A Gene

Function for FAM216A Gene

Animal Model Products

CRISPR Products

miRNA for FAM216A Gene

miRTarBase miRNAs that target FAM216A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM216A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM216A Gene

Localization for FAM216A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM216A Gene

Pathways for FAM216A Gene

SuperPathways for FAM216A Gene

No Data Available

Interacting Proteins for FAM216A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000366901 for FAM216A Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM216A Gene


No data available for Pathways by source for FAM216A Gene

Transcripts for FAM216A Gene

Unigene Clusters for FAM216A Gene

Family with sequence similarity 216, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM216A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM216A Gene

No ASD Table

Relevant External Links for FAM216A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM216A Gene

mRNA expression in normal human tissues for FAM216A Gene

Protein differential expression in normal tissues for FAM216A Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM216A Gene

SOURCE GeneReport for Unigene cluster for FAM216A Gene Hs.436618

genes like me logo Genes that share expressions with FAM216A: view

Expression partners for FAM216A Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM216A Gene

Orthologs for FAM216A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM216A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM216A 35
  • 87.12 (n)
  • 81.67 (a)
FAM216A 36
  • 82 (a)
(Canis familiaris)
Mammalia FAM216A 35
  • 87.66 (n)
  • 79.92 (a)
FAM216A 36
  • 80 (a)
(Mus musculus)
Mammalia Fam216a 35
  • 79.97 (n)
  • 73.56 (a)
Fam216a 16
Fam216a 36
  • 69 (a)
(Pan troglodytes)
Mammalia FAM216A 35
  • 99.22 (n)
  • 98.44 (a)
FAM216A 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam216a 35
  • 79.22 (n)
  • 71.16 (a)
(Monodelphis domestica)
Mammalia FAM216A 36
  • 64 (a)
Species with no ortholog for FAM216A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM216A Gene

Gene Tree for FAM216A (if available)
Gene Tree for FAM216A (if available)

Paralogs for FAM216A Gene

No data available for Paralogs for FAM216A Gene

Variants for FAM216A Gene

Sequence variations from dbSNP and Humsavar for FAM216A Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs756822 -- 110,488,714(-) CAGCC(A/G)TCCAC intron-variant
rs4766429 -- 110,472,600(+) ATTTA(A/C)CCAGA intron-variant
rs7139314 -- 110,486,066(+) GATTC(A/G)CTCTT intron-variant
rs7955913 -- 110,484,996(+) caccc(A/G)gccTA intron-variant
rs7956133 -- 110,485,124(+) AAGCT(G/T)CAAGA reference, synonymous-codon, utr-variant-5-prime

Relevant External Links for FAM216A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM216A Gene

Disorders for FAM216A Gene

No disorders were found for FAM216A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM216A Gene

Publications for FAM216A Gene

  1. Large-scale concatenation cDNA sequencing. (PMID: 9110174) Yu W. … Gibbs R.A. (Genome Res. 1997) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Global identification of modular cullin-RING ligase substrates. (PMID: 21963094) Emanuele M.J. … Elledge S.J. (Cell 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM216A Gene

Sources for FAM216A Gene

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