FAM216A Gene
protein-coding GIFtS: 34
GCID: GC12P110907
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|
family with sequence similarity 216, member A(Previous name: chromosome 12 open reading frame 24 )
(Previous symbol: C12orf24)
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Aliases
for FAM216A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 216, Member A1 2 | | Protein FAM216A2 | | C12orf241 2 3 | | Protein Predicted By Clone 237332 | | HSU792741 2 | | Uncharacterized Protein C12orf242 | | Chromosome 12 Open Reading Frame 241 | | |
Export aliases for FAM216A gene to outside databases |
Summaries
for FAM216A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM216A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_009775.17
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM216A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM216A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM216A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q24.11 Ensembl cytogenetic band: 12q24.11 HGNC cytogenetic band: 12q24.11FAM216A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P110907: view genomic region
(about GC identifiers)
Start:
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110,906,169 bp from pter |
End:
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110,928,192 bp from pter |
Size:
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22,024 bases |
Orientation:
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plus strand |
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Proteins
for FAM216A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F216A_HUMAN, Q8WUB2 (See
protein sequence)Recommended Name: Protein FAM216A Size: 273 amino acids; 30792 Da
Caution: It is uncertain whether Met-1 or Met-18 is the initiator
Secondary accessions: A6NH30 Q99776Explore the universe of human proteins at neXtProt for FAM216A: NX_Q8WUB2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WUB2
FAM216A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_037432.2
ENSEMBL proteins: ENSP00000366901 ENSP00000444508 ENSP00000450157 ENSP00000448777 ENSP00000448594 ENSP00000448530
Human Recombinant Protein Products:
FAM216A Antibody Products:
Assay Products for FAM216A: |
Protein
Domains /
Families
for FAM216A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8WUB2 UniProtKB/Swiss-Prot: F216A_HUMAN, Q8WUB2Similarity: Belongs to the FAM216 family |
Function
for FAM216A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM216A | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM216A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM216A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM216A |
|
Pathways & Interactions
for FAM216A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM216A
|
Drugs & Compounds
for FAM216A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM216A
Search CenterWatch for drugs/clinical trials and news about FAM216A / F216A
|
Transcripts
for FAM216A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM216A gene: NM_013300.2 Unigene Cluster for FAM216A: Family with sequence similarity 216, member A Hs.436618 [show with all ESTs]Unigene Representative Sequence: AK2962806 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377673(uc001tqu.4) ENST00000538285(uc009zvo.2) ENST00000548869(uc010sxz.1)
ENST00000548449 ENST00000546396 ENST00000547539
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM216A | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM216A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM216A |
Additional cDNA sequence: AK225731.1 AK296280.1 AK297684.1 AK308802.1 AK309603.1 BC020967.1 CR457001.1 U79274.1 13 DOTS entries: DT.100791738 DT.113540 DT.100791739 DT.100799611 DT.95330984 DT.121216234 DT.91683593 DT.95248079 DT.121216085 DT.40314176 DT.435149 DT.75199270 DT.95254462 24/133 AceView cDNA sequences (see all 133): U79274 AA523887 BM714167 AA649004 AA451900 AV709924 CR623239 BQ440884 CR623722 AA287898 CR622941 CB121970 BX116128 AA764751 CR595487 BC020967 BQ943229 BU154781 NM_013300 CR609045 AI288620 CR622888 CR602160 BM794710
GeneLoc Exon Structure
|
Expression
for FAM216A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM216A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAACATATAC
About this image
See FAM216A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM216A
SOURCE GeneReport for Unigene cluster: Hs.436618
SABiosciences Custom PCR Arrays for FAM216A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM216A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM216A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM216A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM216A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM216A |
Orthologs
for FAM216A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for FAM216A gene from 1/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Fam216a1 , 5 |
RIKEN cDNA 1500011H22 gene5
family with sequence similarity 216, member A1 |
77.78(n)1
71.6(a)1 |
|
5 (62.33 cM)5
689481 NM_026883.31 NP_081159.11
1223645805 |
ENSEMBL Gene Tree for FAM216A (if available)
TreeFam Gene Tree for FAM216A (if available) |
Paralogs
for FAM216A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for FAM216A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM216A (110906169 - 110928192 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM216A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM216A |
|
Disorders
/ Diseases
for FAM216A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM216A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM216A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM216A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 2 Yu W.... Gibbs R.A. (1997)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1 Andersson B.... Gibbs R.A. (1996)
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External Searches for FAM216A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM216A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM216A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM216A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM216A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM216A gene:
Search GeneIP for patents involving FAM216A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM216A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM216A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM216A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM216A | | | OriGene Protein Over-expression Lysate for FAM216A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM216A | | OriGene 3'-UTR Clone for FAM216A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM216A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM216A | | OriGene Custom Protein Services for FAM216A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM216A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM216A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM216A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM216A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM216A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM216A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM216A |
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 | | | FAM216A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM216A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM216A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM216A |
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