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Aliases for FAM215A Gene

Subcategory (RNA class) for FAM215A Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for FAM215A Gene

  • Family With Sequence Similarity 215 Member A (Non-Protein Coding) 2 3 5
  • Family With Sequence Similarity 215, Member A (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 530 2 3
  • C17orf88 3 4
  • APR-2 3 4
  • Chromosome 17 Open Reading Frame 88 2
  • Apoptosis-Related Protein 2 4
  • Apoptosis Related Protein 3
  • LINC00530 3
  • APR2 4

External Ids for FAM215A Gene

Previous HGNC Symbols for FAM215A Gene

  • C17orf88

Previous GeneCards Identifiers for FAM215A Gene

  • GC17P041995

Summaries for FAM215A Gene

GeneCards Summary for FAM215A Gene

FAM215A (Family With Sequence Similarity 215 Member A (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with FAM215A include large granular lymphocyte leukemia.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM215A Gene

Genomics for FAM215A Gene

Regulatory Elements for FAM215A Gene

Enhancers for FAM215A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM215A on UCSC Golden Path with GeneCards custom track

Promoters for FAM215A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM215A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM215A Gene

Chromosome:
17
Start:
43,917,194 bp from pter
End:
43,917,987 bp from pter
Size:
794 bases
Orientation:
Plus strand

Genomic View for FAM215A Gene

Genes around FAM215A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM215A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM215A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM215A Gene

Proteins for FAM215A Gene

  • Protein details for FAM215A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y5M1-F215A_HUMAN
    Recommended name:
    Uncharacterized protein FAM215A
    Protein Accession:
    Q9Y5M1
    Secondary Accessions:
    • Q6NTD6

    Protein attributes for FAM215A Gene

    Size:
    114 amino acids
    Molecular mass:
    11973 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM215A Gene

Proteomics data for FAM215A Gene at MOPED

Post-translational modifications for FAM215A Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM215A Gene

Domains & Families for FAM215A Gene

Protein Domains for FAM215A Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM215A: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FAM215A Gene

Function for FAM215A Gene

Phenotypes for FAM215A Gene

GenomeRNAi human phenotypes for FAM215A:
genes like me logo Genes that share phenotypes with FAM215A: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM215A Gene

Localization for FAM215A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM215A Gene

Pathways & Interactions for FAM215A Gene

SuperPathways for FAM215A Gene

No Data Available

Interacting Proteins for FAM215A Gene

Gene Ontology (GO) - Biological Process for FAM215A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM215A Gene

Drugs & Compounds for FAM215A Gene

(1) Drugs for FAM215A Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(2) Additional Compounds for FAM215A Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with FAM215A: view

Transcripts for FAM215A Gene

mRNA/cDNA for FAM215A Gene

(3) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM215A Gene

Family with sequence similarity 215, member A (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM215A Gene

No ASD Table

Relevant External Links for FAM215A Gene

GeneLoc Exon Structure for
FAM215A
ECgene alternative splicing isoforms for
FAM215A

Expression for FAM215A Gene

mRNA expression in normal human tissues for FAM215A Gene

mRNA differential expression in normal tissues according to GTEx for FAM215A Gene

This gene is overexpressed in Testis (x16.0).

Protein differential expression in normal tissues from HIPED for FAM215A Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM215A Gene



SOURCE GeneReport for Unigene cluster for FAM215A Gene Hs.721804

genes like me logo Genes that share expression patterns with FAM215A: view

Protein tissue co-expression partners for FAM215A Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM215A Gene

Orthologs for FAM215A Gene

Evolution for FAM215A Gene

ENSEMBL:
Gene Tree for FAM215A (if available)
TreeFam:
Gene Tree for FAM215A (if available)

No data available for Orthologs for FAM215A Gene

Paralogs for FAM215A Gene

No data available for Paralogs for FAM215A Gene

Variants for FAM215A Gene

Variation tolerance for FAM215A Gene

Gene Damage Index Score: 0.48; 10.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM215A Gene

HapMap Linkage Disequilibrium report
FAM215A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for FAM215A Gene

Disorders for FAM215A Gene

MalaCards: The human disease database

(1) MalaCards diseases for FAM215A Gene - From: GeneCards

Disorder Aliases PubMed IDs
large granular lymphocyte leukemia
  • t-cell large granular lymphocyte leukemia
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for FAM215A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM215A
genes like me logo Genes that share disorders with FAM215A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FAM215A Gene

Publications for FAM215A Gene

  1. Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes. (PMID: 10948432) Zhu F. … Wang C.J. (BioTechniques 2000) 2 3 4 67
  2. Oral cancer overexpressed 1 (ORAOV1) regulates cell cycle and apoptosis in cervical cancer HeLa cells. (PMID: 20105337) Jiang L. … Chen Q. (Mol. Cancer 2010) 23
  3. [An experimental study of gemcitabine inducing pancreatic cancer cell apoptosis potentiated by nuclear factor-kappa B P65 siRNA]. (PMID: 20302733) Kong R. … Jiang H.C. (Zhonghua Wai Ke Za Zhi 2010) 23
  4. Curcumin induces chemo/radio-sensitization in ovarian cancer cells and curcumin nanoparticles inhibit ovarian cancer cell growth. (PMID: 20429876) Yallapu M.M. … Chauhan S.C. (J Ovarian Res 2010) 23
  5. Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line. (PMID: 20060462) Ye Y. … Lan M. (Toxicol In Vitro 2010) 23

Products for FAM215A Gene

Sources for FAM215A Gene

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