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Aliases for FAM214A Gene

Aliases for FAM214A Gene

  • Family With Sequence Similarity 214, Member A 2 3
  • KIAA1370 2 3 4
  • Protein FAM214A 3

External Ids for FAM214A Gene

Previous Symbols for FAM214A Gene

  • KIAA1370

Summaries for FAM214A Gene

GeneCards Summary for FAM214A Gene

FAM214A (Family With Sequence Similarity 214, Member A) is a Protein Coding gene. An important paralog of this gene is FAM214B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM214A Gene

Genomics for FAM214A Gene

Genomic Location for FAM214A Gene

52,581,317 bp from pter
52,709,817 bp from pter
128,501 bases
Minus strand

Genomic View for FAM214A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM214A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM214A Gene

No data available for Regulatory Elements for FAM214A Gene

Proteins for FAM214A Gene

  • Protein details for FAM214A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM214A
    Protein Accession:
    Secondary Accessions:
    • A8KA52
    • B4DEP5
    • B4DF40
    • F5H8G0
    • Q32MH6
    • Q4G0R7
    • Q5XJ16
    • Q6PDA3
    • Q9NV24
    • Q9P2H7

    Protein attributes for FAM214A Gene

    1076 amino acids
    Molecular mass:
    121670 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91936.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA92608.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAG57156.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM214A Gene


neXtProt entry for FAM214A Gene

Proteomics data for FAM214A Gene at MOPED

Post-translational modifications for FAM214A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM214A Gene

Domains for FAM214A Gene

Protein Domains for FAM214A Gene



  • Belongs to the FAM214 family.:
    • Q32MH5
genes like me logo Genes that share domains with FAM214A: view

No data available for Gene Families for FAM214A Gene

Function for FAM214A Gene

Gene Ontology (GO) - Molecular Function for FAM214A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM214A: view

miRNA for FAM214A Gene

miRTarBase miRNAs that target FAM214A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM214A Gene

Localization for FAM214A Gene

No data available for Gene Ontology (GO) - Cellular Components for FAM214A Gene

Pathways for FAM214A Gene

SuperPathways for FAM214A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM214A Gene


No data available for Pathways by source for FAM214A Gene

Transcripts for FAM214A Gene

Unigene Clusters for FAM214A Gene

Family with sequence similarity 214, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM214A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b
SP1: - -
SP2: - - - -
SP3: - - - - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: - - - - - -
SP8: -

Relevant External Links for FAM214A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM214A Gene

mRNA expression in normal human tissues for FAM214A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM214A Gene

SOURCE GeneReport for Unigene cluster for FAM214A Gene Hs.152385

genes like me logo Genes that share expressions with FAM214A: view

Orthologs for FAM214A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM214A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM214A 36
  • 99.54 (n)
  • 99.54 (a)
FAM214A 37
  • 98 (a)
(Bos Taurus)
Mammalia FAM214A 37
  • 84 (a)
KIAA1370 36
  • 89.9 (n)
  • 85.49 (a)
(Canis familiaris)
Mammalia FAM214A 37
  • 84 (a)
KIAA1370 36
  • 90.16 (n)
  • 85.29 (a)
(Mus musculus)
Mammalia Fam214a 36
  • 78.39 (n)
  • 75.56 (a)
Fam214a 16
Fam214a 37
  • 74 (a)
(Monodelphis domestica)
Mammalia FAM214A 37
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia FAM214A 37
  • 67 (a)
(Rattus norvegicus)
Mammalia Fam214a 36
  • 78.81 (n)
  • 75.94 (a)
(Gallus gallus)
Aves FAM214A 36
  • 72.61 (n)
  • 67.98 (a)
FAM214A 37
  • 66 (a)
(Anolis carolinensis)
Reptilia FAM214A 37
  • 65 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.6950 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2731 36
(Danio rerio)
Actinopterygii fam214a 37
  • 47 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9005 37
  • 15 (a)
Species with no ortholog for FAM214A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM214A Gene

Gene Tree for FAM214A (if available)
Gene Tree for FAM214A (if available)

Paralogs for FAM214A Gene

Paralogs for FAM214A Gene

Selected SIMAP similar genes for FAM214A Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with FAM214A: view

Variants for FAM214A Gene

Sequence variations from dbSNP and Humsavar for FAM214A Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs877974 -- 52,674,211(-) AATGT(C/G)GTCTT intron-variant
rs877975 -- 52,674,030(-) AGGCT(A/G)TTGAT intron-variant
rs933858 -- 52,642,205(-) TATTA(C/T)AGCTA intron-variant
rs933859 -- 52,642,085(-) TTTCA(G/T)AATAA intron-variant
rs933860 -- 52,673,271(+) CACAA(C/T)ACTTA intron-variant

Relevant External Links for FAM214A Gene

HapMap Linkage Disequilibrium report

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM214A Gene

Disorders for FAM214A Gene

No disorders were found for FAM214A Gene.

No data available for UniProtKB/Swiss-Prot for FAM214A Gene

Publications for FAM214A Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for FAM214A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM214A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM214A
    • Block miRNA regulation of FAM214A using miScript Target Protectors

    Sources for FAM214A Gene

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