FAM214A Gene
protein-coding GIFtS : 39
GCID: GC15 M053028
family with sequence similarity 214, member A (Previous name: KIAA1370 ) (Previous symbol: KIAA1370 )
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Aliasesfor FAM214A gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Family With Sequence Similarity 214, Member A 1 2 KIAA13701 2 3 FLJ109801 Protein FAM214A2
Export aliases for FAM214A gene to outside databases Previous GC identifers: GC15M052874 GC15M052876
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Summariesfor FAM214A gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor FAM214A gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000015.9 NC_018926.1 NT_010194.17 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for FAM214A Other transcription factors Search SABiosciences Chromatin IP Primers for FAM214A Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM214A
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 15q21.2-q21.3 Ensembl cytogenetic band: 15q21.3 HGNC cytogenetic band: 15q21.2-q21.3 FAM214A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 15 GeneLoc Exon Structure
GeneLoc location for GC15M053028: view genomic region
(about GC identifiers )
Start:
52,873,514 bp from pter
End:
53,002,014 bp from pter
Size:
128,501 bases
Orientation:
minus strand
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Proteinsfor FAM214A gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: F214A_HUMAN, Q32MH5 (See
protein sequence )Recommended Name: Protein FAM214A Size : 1076 amino acids; 121670 Da
Sequence caution : Sequence=BAA91936.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAA92608.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAG57156.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions : A8KA52 B4DEP5 B4DF40 F5H8G0 Q32MH6 Q4G0R7 Q5XJ16 Q6PDA3 Q9NV24 Q9P2H7Alternative splicing : 3 isoforms : Q32MH5-1 Q32MH5-2 Q32MH5-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM214A: NX_Q32MH5 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q32MH5 FAM214A Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_062546.2 ENSEMBL proteins: ENSP00000261844 ENSP00000444447 ENSP00000443598 ENSP00000458036 ENSP00000382153 ENSP00000455002 ENSP00000457666 ENSP00000455578 ENSP00000457402 ENSP00000457120 ENSP00000456725 Human Recombinant Protein Products for FAM214A: FAM214A Antibody Products: Assay Products for FAM214A:
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Protein
Domains / Familiesfor FAM214A gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FAM214A for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q32MH5 ProtoNet protein and cluster: Q32MH5
UniProtKB/Swiss-Prot: F214A_HUMAN, Q32MH5 Similarity : Belongs to the FAM214 family
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Functionfor FAM214A gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214A (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214AOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript Custom all cDNA clones Services for FAM214A Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM214A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM214A
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM214A
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Pathways & Interactionsfor FAM214A gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM214A STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for FAM214A (Q32MH5 3 ENSP00000261844 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor FAM214A gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for FAM214A Search CenterWatch for drugs/clinical trials and news about FAM214A / F214A
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Transcriptsfor FAM214A gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for FAM214A gene: NM_019600.2 Unigene Cluster for FAM214A:
Family with sequence similarity 214, member A Hs.152385 [show with all ESTs ] Unigene Representative Sequence: NM_019600 15 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000568871 (uc002acf.4 ) ENST00000261844 (uc010ugf.2 uc002acg.4 )ENST00000534964 (uc002ach.4 ) ENST00000546305 ENST00000568637 ENST00000399202 (uc010bfg.1 )ENST00000570204 ENST00000566948 ENST00000568668 ENST00000562135 ENST00000566768 ENST00000561490 ENST00000561543 ENST00000568863 ENST00000562351 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214A (see all 4 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214AOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript Custom all cDNA clones Services for FAM214A DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM214A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM214A
Additional cDNA sequence: AB037791.1 AK001842.1 AK292917.1 AK293730.1 AK293920.1 AK308049.1 AK308855.1 AL832519.1 BC058839.1 BC073908.1 BC083498.1 BC109127.1 BC109128.2
14 DOTS entries : DT.97838373 DT.446416
DT.100643074 DT.121034168 DT.40211411 DT.100708329 DT.91735969 DT.95069004 DT.100813601 DT.99951427 DT.99994988 DT.121034092 DT.40192332 DT.95272986 24/154 AceView cDNA sequences (see all 154 ):
BX472940 BC058839 Z42734 AA808378 AA322716 BU686792 BE646439 AI128013 CA447920 BQ438938 AA456383 BM978889 BX503913 BM977065 BE676401 AA724154 BE501898 BQ884323 AA251559 AI222169 AI469328 AA768149 BF513802 W32268 GeneLoc Exon Structure 5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM214A (see all 8 ) About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b SP1 :             -     -                                   SP2 :           -   -     -                           -         SP3 :   -   -   -   -   -   -     -                                   SP4 :     -   -   -   -   -     -                                   SP5 :       -   -   -   -     -                                  
ECgene alternative splicing isoforms for FAM214A
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Expression for FAM214A gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section FAM214A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image FAM214A expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Bone Thoracic Rib Bone Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See FAM214A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FAM214A SOURCE GeneReport for Unigene cluster: Hs.152385 SABiosciences Custom PCR Arrays for FAM214A Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM214ABrowse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM214A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM214A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM214A In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM214A
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Orthologsfor FAM214A gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for FAM214A gene from 6/19 species (see all 19 ) About this table
ENSEMBL Gene Tree for FAM214A (if available)TreeFam Gene Tree for FAM214A (if available)
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Paralogsfor FAM214A gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for FAM214A gene FAM214B 2 3 SIMAP similar genes for FAM214A using alignment to 9 protein entries: F214A_HUMAN (see all proteins ):DKFZp666F111 KIAA1370 FAM214B
FAM214A for paralogs About GeneDecksing
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Genomic Variantsfor FAM214A gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 15 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for FAM214A (52873514 - 53002014 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FAM214A: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM214A
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Disorders
/ Diseasesfor FAM214A gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section --
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Publicationsfor FAM214A gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for FAM214A gene integrated from 9 sources : (articles sorted by number of sources associating them with FAM214A) Utopia : connect your pdf to the dynamic world of online information
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198) 1 , 2 , 3 Nagase T.... Ohara O. (2000) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 Ota T.... Sugano S. (2004) Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724) 1 Udeshi N.D....Carr S.A. (2012) Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118) 1 Woods N.T....Monteiro A.N. (2012) A human MAP kinase interactome. (PubMed id 20936779) 1 Bandyopadhyay S....Ideker T. (2010) Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171) 2 Zody M.C....Nusbaum C. (2006) Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560) 1 Kimura K.... Sugano S. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM214A gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FAM214A gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing FAM214A gene
(According to HUGE )
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Specialized Databases showing FAM214A gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for FAM214A Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for FAM214A gene: Search GeneIP for patents involving FAM214A GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FAM214A gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for FAM214A OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for FAM214A OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM214A Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for FAM214A OriGene 3'-UTR Clone for FAM214A OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214A OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM214A Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for FAM214A OriGene Custom Protein Services for FAM214A OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM214A QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM214A QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM214A QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat FAM214A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM214A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM214A
Search Tocris compounds for FAM214A
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM214A
Search ThermoFisher Antibodies for FAM214A
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM214A
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Aliases for FAM214A
Databases for FAM214A
Disorders / Diseases for FAM214A
Domains / Families for FAM214A
Drugs / Compounds for FAM214A
Expression for FAM214A
Function for FAM214A
Genomic Views for FAM214A
Intellectual Property for FAM214A
Orthologs for FAM214A
Paralogs for FAM214A
Pathways / Interactions for FAM214A
Products for FAM214A
Proteins for FAM214A
Publications for FAM214A
Search Box for FAM214A
Summaries for FAM214A
Transcripts for FAM214A
Variants for FAM214A
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