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Aliases for FAM214A Gene

Aliases for FAM214A Gene

  • Family With Sequence Similarity 214, Member A 2 3
  • KIAA1370 2 3 4
  • Protein FAM214A 3

External Ids for FAM214A Gene

Previous HGNC Symbols for FAM214A Gene

  • KIAA1370

Previous GeneCards Identifiers for FAM214A Gene

  • GC15M052874
  • GC15M052876
  • GC15M053028
  • GC15M053500
  • GC15M054147

Summaries for FAM214A Gene

GeneCards Summary for FAM214A Gene

FAM214A (Family With Sequence Similarity 214, Member A) is a Protein Coding gene. An important paralog of this gene is FAM214B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM214A Gene

Genomics for FAM214A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM214A Gene

52,581,317 bp from pter
52,709,817 bp from pter
128,501 bases
Minus strand

Genomic View for FAM214A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM214A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM214A Gene

No data available for Regulatory Elements for FAM214A Gene

Proteins for FAM214A Gene

  • Protein details for FAM214A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM214A
    Protein Accession:
    Secondary Accessions:
    • A8KA52
    • B4DEP5
    • B4DF40
    • F5H8G0
    • Q32MH6
    • Q4G0R7
    • Q5XJ16
    • Q6PDA3
    • Q9NV24
    • Q9P2H7

    Protein attributes for FAM214A Gene

    1076 amino acids
    Molecular mass:
    121670 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91936.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAA92608.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAG57156.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM214A Gene


neXtProt entry for FAM214A Gene

Proteomics data for FAM214A Gene at MOPED

Post-translational modifications for FAM214A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM214A Gene

Domains for FAM214A Gene

Protein Domains for FAM214A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM214 family.
  • Belongs to the FAM214 family.
genes like me logo Genes that share domains with FAM214A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM214A Gene

Function for FAM214A Gene

Gene Ontology (GO) - Molecular Function for FAM214A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM214A: view

Animal Model Products

CRISPR Products

miRNA for FAM214A Gene

miRTarBase miRNAs that target FAM214A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM214A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM214A Gene

Localization for FAM214A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM214A Gene

Pathways for FAM214A Gene

SuperPathways for FAM214A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM214A Gene


No data available for Pathways by source for FAM214A Gene

Transcripts for FAM214A Gene

Unigene Clusters for FAM214A Gene

Family with sequence similarity 214, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM214A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM214A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b
SP1: - -
SP2: - - - -
SP3: - - - - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: - - - - - -
SP8: -

Relevant External Links for FAM214A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM214A Gene

mRNA expression in normal human tissues for FAM214A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for FAM214A Gene

This gene is overexpressed in Liver (35.5), Plasma (13.9), and Blymphocyte (11.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM214A Gene

SOURCE GeneReport for Unigene cluster for FAM214A Gene Hs.152385

genes like me logo Genes that share expressions with FAM214A: view

Expression partners for FAM214A Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM214A Gene

Orthologs for FAM214A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM214A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KIAA1370 35
  • 89.9 (n)
  • 85.49 (a)
FAM214A 36
  • 84 (a)
(Canis familiaris)
Mammalia KIAA1370 35
  • 90.16 (n)
  • 85.29 (a)
FAM214A 36
  • 84 (a)
(Mus musculus)
Mammalia Fam214a 35
  • 78.39 (n)
  • 75.56 (a)
Fam214a 16
Fam214a 36
  • 74 (a)
(Pan troglodytes)
Mammalia FAM214A 35
  • 99.54 (n)
  • 99.54 (a)
FAM214A 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam214a 35
  • 78.81 (n)
  • 75.94 (a)
(Monodelphis domestica)
Mammalia FAM214A 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia FAM214A 36
  • 67 (a)
(Gallus gallus)
Aves FAM214A 35
  • 72.61 (n)
  • 67.98 (a)
FAM214A 36
  • 66 (a)
(Anolis carolinensis)
Reptilia FAM214A 36
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.2731 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.6950 35
(Danio rerio)
Actinopterygii fam214a 36
  • 47 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9005 36
  • 15 (a)
Species with no ortholog for FAM214A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM214A Gene

Gene Tree for FAM214A (if available)
Gene Tree for FAM214A (if available)

Paralogs for FAM214A Gene

Paralogs for FAM214A Gene

genes like me logo Genes that share paralogs with FAM214A: view

Variants for FAM214A Gene

Sequence variations from dbSNP and Humsavar for FAM214A Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs877974 -- 52,674,211(-) AATGT(C/G)GTCTT intron-variant
rs877975 -- 52,674,030(-) AGGCT(A/G)TTGAT intron-variant
rs933858 -- 52,642,205(-) TATTA(C/T)AGCTA intron-variant
rs933859 -- 52,642,085(-) TTTCA(G/T)AATAA intron-variant
rs933860 -- 52,673,271(+) CACAA(C/T)ACTTA intron-variant

Relevant External Links for FAM214A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM214A Gene

Disorders for FAM214A Gene

No disorders were found for FAM214A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM214A Gene

Publications for FAM214A Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3
  5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for FAM214A Gene

Sources for FAM214A Gene

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