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FAM213B Gene

protein-coding   GIFtS: 48
GCID: GC01P002517

Family With Sequence Similarity 213, Member B

(Previous name: chromosome 1 open reading frame 93)
(Previous symbol: C1orf93)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
Family With Sequence Similarity 213, Member B1 2     Prostamide/PGF Synthase2 3
C1orf931 2 3     Chromosome 1 Open Reading Frame 931
Prostamide/Prostaglandin F Synthase1 2     EC 1.11.1.203
Prostamide/PG F Synthase2 3     Protein FAM213B3

External Ids:    HGNC: 283901   Entrez Gene: 1272812   Ensembl: ENSG000001578707   UniProtKB: Q8TBF23   
ORGUL members:         

Export aliases for FAM213B gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM213B Gene:
FAM213B (family with sequence similarity 213, member B) is a protein-coding gene. GO annotations related to this gene include oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. An important paralog of this gene is FAM213A.

UniProtKB/Swiss-Prot: PGFS_HUMAN, Q8TBF2
Function: Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha)
with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NT_187515.1  NC_018912.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for FAM213B
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for FAM213B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM213B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.32   Ensembl cytogenetic band:  1p36.32   HGNC cytogenetic band: 1p36.32

FAM213B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM213B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P002517:  view genomic region     (about GC identifiers)

Start:
2,517,899 bp from pter      End:
2,522,908 bp from pter
Size:
5,010 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: PGFS_HUMAN, Q8TBF2 (See protein sequence)
Recommended Name: Prostamide/prostaglandin F synthase  
Size: 198 amino acids; 21223 Da
Secondary accessions: A8K793 B3KPY3 B4DQR9 B4E0S5 B7ZAC8 B9DI90 B9DI92 J3KQD0 Q8N2H0
Alternative splicing: 8 isoforms:  Q8TBF2-1   Q8TBF2-2   Q8TBF2-3   Q8TBF2-4   Q8TBF2-5   Q8TBF2-6   Q8TBF2-7   Q8TBF2-8   
(No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM213B: NX_Q8TBF2

Explore proteomics data for FAM213B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys101, Lys120
  • Modification sites at PhosphoSitePlus

  • See FAM213B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001182665.1  NP_001182666.1  NP_001182667.1  NP_001182669.1  NP_001182670.1  NP_689584.2  

    ENSEMBL proteins: 
     ENSP00000394405   ENSP00000367681   ENSP00000367684   ENSP00000462185   ENSP00000463127  
     ENSP00000443605   ENSP00000367682   ENSP00000413218  
    Reactome Protein details: Q8TBF2

    FAM213B Human Recombinant Protein Products:

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    Novus Biologicals FAM213B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for FAM213B 

     
    antibodies-online proteins for FAM213B (7 products) 

     
    antibodies-online peptides for FAM213B

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    antibodies-online antibodies for FAM213B (18 products) 

    FAM213B Assay Products:

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    Search eBioscience for ELISAs for FAM213B 
    antibodies-online kits for FAM213B (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR012336 Thioredoxin-like_fold

    Graphical View of Domain Structure for InterPro Entry Q8TBF2

    ProtoNet protein and cluster: Q8TBF2

    UniProtKB/Swiss-Prot: PGFS_HUMAN, Q8TBF2
    Similarity: Belongs to the peroxiredoxin-like FAM213 family. Prostamide/prostaglandin F synthase subfamily


    Find genes that share domains with FAM213B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PGFS_HUMAN, Q8TBF2
    Function: Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha)
    with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity)
    Catalytic activity: Thioredoxin + prostaglandin H(2) = thioredoxin disulfide + prostaglandin F(2-alpha)

         Enzyme Number (IUBMB): EC 1.11.1.201

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor ISS--
    GO:0047017prostaglandin-F synthase activity ISS18006499
         
    Find genes that share ontologies with FAM213B           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for FAM213B:
     Decreased TP53 protein express 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FAM213B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM213B:
    hsa-mir-760 (MIRT036744), hsa-mir-128-3p (MIRT021925)

    Block miRNA regulation of human, mouse, rat FAM213B using miScript Target Protectors
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM213B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PGFS_HUMAN, Q8TBF2: Cytoplasm, cytosol (By similarity)

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS18006499
    GO:0005783endoplasmic reticulum ISS18006499
    GO:0005829cytosol IEA--
    GO:0043209myelin sheath ISS18006499
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with FAM213B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for FAM213B About    
    See pathways by source

    SuperPathContained pathways About
    1Arachidonic acid metabolism
    Arachidonic acid metabolism0.41
    Synthesis of Prostaglandins (PG) and Thromboxanes (TX)0.00
    Arachidonic acid metabolism0.40
    2Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38


    Find genes that share SuperPaths with FAM213B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Reactome Pathway for FAM213B
        Synthesis of Prostaglandins (PG) and Thromboxanes (TX)


    2 Kegg Pathways  (Kegg details for FAM213B):
        Arachidonic acid metabolism
    Metabolic pathways

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM213B
    Interactions:

        Search GeneGlobe Interaction Network for FAM213B

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for FAM213B (Q8TBF22, 3 ENSP000003676824) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PDPK1O155302, 3MINT-8265488 I2D: score=2 
    TNFSF11O147882, 3, ENSP000002398494MINT-8274643 I2D: score=2 STRING: ENSP00000239849
    ATP2B4ENSP000003503104STRING: ENSP00000350310
    UBCENSP000003448184STRING: ENSP00000344818
    --ENSP000003873584STRING: ENSP00000387358
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001516prostaglandin biosynthetic process ISS--
    GO:0019369arachidonic acid metabolic process TAS--
    GO:0019371cyclooxygenase pathway TAS--
    GO:0044281small molecule metabolic process TAS--

    Find genes that share ontologies with FAM213B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM213B (PGFS)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM213B gene (6 alternative transcripts): 
    NM_001195736.1  NM_001195737.1  NM_001195738.1  NM_001195740.1  NM_001195741.1  NM_152371.3  

    Unigene Cluster for FAM213B:

    Family with sequence similarity 213, member B
    Hs.462033  [show with all ESTs]
    Unigene Representative Sequence: NM_001195736
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000493183 ENST00000474659 ENST00000419916(uc021oex.1 uc001ajw.2 uc001aju.2 uc010nzd.2 uc010nze.2 uc010nzf.2)
    ENST00000378424(uc001ajv.2) ENST00000378427 ENST00000464043 ENST00000465233
    ENST00000498083 ENST00000481683 ENST00000484099(uc021oew.1 uc001ajx.2)
    ENST00000477045 ENST00000476686 ENST00000537325 ENST00000378425 ENST00000444521

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidFAM213B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM213B
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    Primer
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    OriGene qPCR primer pairs and template standards for FAM213B
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    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat FAM213B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM213B
      QuantiFast Probe-based Assays in human, mouse, rat FAM213B

    Additional mRNA sequence: 

    AF425266.1 AK057027.1 AK075273.1 AK094901.1 AK291908.1 AK298926.1 AK303504.1 AK308034.1 
    AK316243.1 BC022547.1 CR749706.1 NR_036637.1 NR_036638.1 

    12 DOTS entries:

    DT.215282  DT.100037314  DT.92424804  DT.121368270  DT.100820414  DT.95325040  DT.95325054  DT.95111945 
    DT.121368250  DT.99963106  DT.121368307  DT.92424803 

    Selected AceView cDNA sequences (see all 205):

    BM976058 BG152535 AA351960 BF222433 CD672662 AI880345 BQ668422 BM773263 
    BQ881301 BU528623 BM715492 BF513513 BQ943393 BM773051 AK057027 BQ687841 
    BF001433 BU632313 CB156698 AL359575 CF132707 CR749706 AW006103 AI888306 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM213B (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c · 3d ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e · 7f ^
    SP1:                          -     -     -     -     -     -     -     -                       -           -                                                   
    SP2:                          -     -     -     -     -     -     -     -                       -           -                 -                                 
    SP3:                                                              -     -                       -           -                                                   
    SP4:                                                              -     -                       -           -                 -                                 
    SP5:                          -     -     -     -     -     -     -     -                       -           -                 -                                 

    ExUns: 8a · 8b · 8c · 8d · 8e · 8f · 8g
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for FAM213B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM213B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAATCCTGA
    FAM213B Expression
    About this image

    FAM213B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM213B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.462033
        Custom PCR Arrays for FAM213B
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM213B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM213B gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam213b1 , 5 RIKEN cDNA 2810405K02 gene5
    family with sequence similarity 213, member B1
    83.16(n)1
    88.38(a)1
      4 (85.67 cM)5
    664691  NM_025582.31  NP_079858.21 
     1548955045 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.94722 Xenopus laevis transcribed sequence with weak similarity more 67.99(n)    48050014 
    zebrafish
    (Danio rerio)
    Actinopterygii fam213b1 family with sequence similarity 213, member B 62.12(n)
    59.6(a)
      406605  NM_213313.1  NP_998478.1 
    worm
    (Caenorhabditis elegans)
    Secernentea R53.56
    Protein R53.5 (R53.5) mRNA, complete cds
    19(a)
    1 → many
    II(9969615-9970515) WBGene00011274


    ENSEMBL Gene Tree for FAM213B (if available)
    TreeFam Gene Tree for FAM213B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM213B gene
    FAM213A2  
    1 SIMAP similar gene for FAM213B using alignment to 5 protein entries:     PGFS_HUMAN (see all proteins):
    FAM213A

    Find genes that share paralogs with FAM213B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM213B (see all 127)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1444230871,2
    C,F--1802574(+) GAGATC/TCAGGC 8 -- int12Minor allele frequency- T:0.00NA EU 5691
    rs1417638941,2
    C,F--1802580(+) CAGGCC/TGGGCA 8 -- int11Minor allele frequency- T:0.00NA 4542
    rs1399419531,2
    C,F--1802593(+) TGCTGG/TTCCTT 8 -- int12Minor allele frequency- T:0.00NA EU 5679
    rs1914616241,2
    --2516550(+) ATGGCA/GTTGGT 8 -- us2k10--------
    rs1833161001,2
    --2516583(+) GATCTC/TGCATT 8 -- us2k10--------
    rs607334001,2
    C,F--2516781(+) AGCCCA/GAGACA 8 -- us2k16Minor allele frequency- G:0.49WA NA CSA EA 364
    rs1468631641,2
    C--2516821(+) ACGGT-/G/GG  
            
    GGGGG
    8 -- us2k10--------
    rs728485931,2
    C,F--2517049(+) GTTTCG/ACAGTC 8 -- us2k13Minor allele frequency- A:0.10WA 122
    rs765607901,2
    F--2517106(+) CCCCCC/TCGGGG 8 -- us2k11Minor allele frequency- T:0.01NA 120
    rs743900021,2
    --2517308(+) CAAAAA/GCTATC 8 -- us2k10--------

    HapMap Linkage Disequilibrium report for FAM213B (2517899 - 2522908 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FAM213B: --
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FAM213B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM213B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM213B gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with FAM213B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of a novel type of prostamide/prostaglandin F synthase, belonging to the thioredoxin-like superfamily. (PubMed id 18006499)1, 3 Moriuchi H....Watanabe K. (J. Biol. Chem. 2008)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    5. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    6. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    7. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. (PubMed id 21297633)1 Anderson C.A....Rioux J.D. (Nat. Genet. 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 127281 HGNC: 28390 AceView: MGC26818 Ensembl:ENSG00000157870 euGenes: HUgn127281
    ECgene: FAM213B Kegg: 127281 H-InvDB: FAM213B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM213B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM213B gene:
    Search GeneIP for patents involving FAM213B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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