Aliases for FAM213A Gene
External Ids for FAM213A Gene
Previous HGNC Symbols for FAM213A Gene
Previous GeneCards Identifiers for FAM213A Gene
GeneCards Summary for FAM213A Gene
FAM213A (Family With Sequence Similarity 213 Member A) is a Protein Coding gene. Diseases associated with FAM213A include Common Bile Duct Disease. GO annotations related to this gene include antioxidant activity. An important paralog of this gene is FAM213B.
UniProtKB/Swiss-Prot for FAM213A Gene
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).