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Aliases for FAM212B Gene

Aliases for FAM212B Gene

  • Family With Sequence Similarity 212 Member B 2 3 5
  • C1orf183 3 4
  • Family With Sequence Similarity 212, Member B 2
  • Chromosome 1 Open Reading Frame 183 2
  • Protein FAM212B 3

External Ids for FAM212B Gene

Previous HGNC Symbols for FAM212B Gene

  • C1orf183

Previous GeneCards Identifiers for FAM212B Gene

  • GC01M112223

Summaries for FAM212B Gene

GeneCards Summary for FAM212B Gene

FAM212B (Family With Sequence Similarity 212 Member B) is a Protein Coding gene. An important paralog of this gene is FAM212A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM212B Gene

Genomics for FAM212B Gene

Regulatory Elements for FAM212B Gene

Enhancers for FAM212B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FAM212B on UCSC Golden Path with GeneCards custom track

Promoters for FAM212B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM212B Gene

111,680,630 bp from pter
111,755,824 bp from pter
75,195 bases
Minus strand

Genomic View for FAM212B Gene

Genes around FAM212B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM212B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM212B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM212B Gene

Proteins for FAM212B Gene

  • Protein details for FAM212B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM212B
    Protein Accession:
    Secondary Accessions:
    • B3KP38
    • B4DF94
    • Q9NTI6

    Protein attributes for FAM212B Gene

    297 amino acids
    Molecular mass:
    32759 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM212B Gene


neXtProt entry for FAM212B Gene

Post-translational modifications for FAM212B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM212B Gene

No data available for DME Specific Peptides for FAM212B Gene

Domains & Families for FAM212B Gene

Protein Domains for FAM212B Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM212 family.
  • Belongs to the FAM212 family.
genes like me logo Genes that share domains with FAM212B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM212B Gene

Function for FAM212B Gene

genes like me logo Genes that share phenotypes with FAM212B: view

Animal Model Products

CRISPR Products

miRNA for FAM212B Gene

miRTarBase miRNAs that target FAM212B

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM212B Gene

Localization for FAM212B Gene

Subcellular locations from

Jensen Localization Image for FAM212B Gene COMPARTMENTS Subcellular localization image for FAM212B gene
Compartment Confidence
nucleus 4
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM212B Gene

Pathways & Interactions for FAM212B Gene

SuperPathways for FAM212B Gene

No Data Available

Interacting Proteins for FAM212B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000349805 Q9NTI7-F212B_HUMAN for FAM212B Gene via STRING IID

Gene Ontology (GO) - Biological Process for FAM212B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM212B Gene

Drugs & Compounds for FAM212B Gene

No Compound Related Data Available

Transcripts for FAM212B Gene

Unigene Clusters for FAM212B Gene

Family with sequence similarity 212, member B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM212B Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c
SP1: -

Relevant External Links for FAM212B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM212B Gene

mRNA expression in normal human tissues for FAM212B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM212B Gene

This gene is overexpressed in Whole Blood (x12.5).

NURSA nuclear receptor signaling pathways regulating expression of FAM212B Gene:


SOURCE GeneReport for Unigene cluster for FAM212B Gene:

genes like me logo Genes that share expression patterns with FAM212B: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM212B Gene

Orthologs for FAM212B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM212B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM212B 34
  • 85.95 (n)
  • 86.06 (a)
FAM212B 35
  • 83 (a)
(Mus musculus)
Mammalia Fam212b 34
  • 80.13 (n)
  • 79.8 (a)
Fam212b 16
Fam212b 35
  • 79 (a)
(Pan troglodytes)
Mammalia FAM212B 34
  • 99.44 (n)
  • 100 (a)
FAM212B 35
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam212b 34
  • 80.36 (n)
  • 78.45 (a)
(Monodelphis domestica)
Mammalia FAM212B 35
  • 65 (a)
(Ornithorhynchus anatinus)
Mammalia FAM212B 35
  • 50 (a)
(Gallus gallus)
Aves C1ORF183 34
  • 62.85 (n)
  • 61.62 (a)
FAM212B 35
  • 49 (a)
(Anolis carolinensis)
Reptilia FAM212B 35
  • 40 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam212b 34
  • 54.41 (n)
  • 47.43 (a)
Str.19495 34
(Danio rerio)
Actinopterygii LOC101886856 34
  • 48.65 (n)
  • 38.16 (a)
Species where no ortholog for FAM212B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM212B Gene

Gene Tree for FAM212B (if available)
Gene Tree for FAM212B (if available)

Paralogs for FAM212B Gene

Paralogs for FAM212B Gene

genes like me logo Genes that share paralogs with FAM212B: view

Variants for FAM212B Gene

Sequence variations from dbSNP and Humsavar for FAM212B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs85278 -- 111,733,490(-) TTTGC(A/G)CTTCC intron-variant
rs108406 -- 111,731,986(+) AGCCA(C/T)GTTCA intron-variant
rs127204 -- 111,735,071(+) AAGTA(A/C)AACTT intron-variant
rs183193 -- 111,727,937(+) TCTCT(A/C)TATAG intron-variant
rs197424 -- 111,723,120(+) ATGGG(A/G)AAGGC utr-variant-3-prime

Variation tolerance for FAM212B Gene

Residual Variation Intolerance Score: 55.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.76; 16.06% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM212B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM212B Gene

Disorders for FAM212B Gene

Relevant External Links for FAM212B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM212B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM212B Gene

Publications for FAM212B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3 65
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 65
  5. Biochemical and computational analysis of LNX1 interacting proteins. (PMID: 22087225) Wolting C.D. … McGlade C.J. (PLoS ONE 2011) 3 65

Products for FAM212B Gene

Sources for FAM212B Gene

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