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Aliases for FAM212A Gene

Aliases for FAM212A Gene

  • Family With Sequence Similarity 212 Member A 2 3 5
  • Family With Sequence Similarity 212, Member A 2 3
  • C3orf54 3 4
  • Chromosome 3 Open Reading Frame 54 2
  • INKA1 3

External Ids for FAM212A Gene

Previous HGNC Symbols for FAM212A Gene

  • C3orf54

Summaries for FAM212A Gene

GeneCards Summary for FAM212A Gene

FAM212A (Family With Sequence Similarity 212 Member A) is a Protein Coding gene. An important paralog of this gene is FAM212B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM212A Gene

Genomics for FAM212A Gene

Regulatory Elements for FAM212A Gene

Enhancers for FAM212A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM212A on UCSC Golden Path with GeneCards custom track

Promoters for FAM212A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM212A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM212A Gene

49,803,233 bp from pter
49,805,033 bp from pter
1,801 bases
Plus strand

Genomic View for FAM212A Gene

Genes around FAM212A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM212A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM212A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM212A Gene

Proteins for FAM212A Gene

  • Protein details for FAM212A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM212A
    Protein Accession:

    Protein attributes for FAM212A Gene

    285 amino acids
    Molecular mass:
    31328 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH12170.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for FAM212A Gene

neXtProt entry for FAM212A Gene

Proteomics data for FAM212A Gene at MOPED

Post-translational modifications for FAM212A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM212A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM212A Gene

Domains & Families for FAM212A Gene

Protein Domains for FAM212A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM212 family.
  • Belongs to the FAM212 family.
genes like me logo Genes that share domains with FAM212A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM212A Gene

Function for FAM212A Gene

genes like me logo Genes that share phenotypes with FAM212A: view

Animal Models for FAM212A Gene

MGI Knock Outs for FAM212A:

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for FAM212A Gene

Localization for FAM212A Gene

Subcellular locations from

Jensen Localization Image for FAM212A Gene COMPARTMENTS Subcellular localization image for FAM212A gene
Compartment Confidence
extracellular 5
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM212A Gene

Pathways & Interactions for FAM212A Gene

SuperPathways for FAM212A Gene

No Data Available

Interacting Proteins for FAM212A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000329735 Q96EL1-F212A_HUMAN for FAM212A Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for FAM212A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM212A Gene

Drugs & Compounds for FAM212A Gene

No Compound Related Data Available

Transcripts for FAM212A Gene

mRNA/cDNA for FAM212A Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM212A Gene

Family with sequence similarity 212, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM212A Gene

No ASD Table

Relevant External Links for FAM212A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM212A Gene

mRNA expression in normal human tissues for FAM212A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM212A Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x4.3) and Skin - Not Sun Exposed (Suprapubic) (x4.0).

Protein differential expression in normal tissues from HIPED for FAM212A Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM212A Gene

SOURCE GeneReport for Unigene cluster for FAM212A Gene Hs.86674

genes like me logo Genes that share expression patterns with FAM212A: view

Protein tissue co-expression partners for FAM212A Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for FAM212A Gene

Orthologs for FAM212A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM212A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM212A 35
  • 85.58 (n)
  • 83.33 (a)
FAM212A 36
  • 83 (a)
(Canis familiaris)
Mammalia FAM212A 35
  • 85.29 (n)
  • 81.85 (a)
FAM212A 36
  • 83 (a)
(Mus musculus)
Mammalia Fam212a 35
  • 83.1 (n)
  • 80.5 (a)
Fam212a 16
Fam212a 36
  • 79 (a)
(Pan troglodytes)
Mammalia FAM212A 35
  • 99.65 (n)
  • 98.95 (a)
FAM212A 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam212a 35
  • 83.1 (n)
  • 81.21 (a)
(Monodelphis domestica)
Mammalia FAM212A 36
  • 58 (a)
(Gallus gallus)
Aves FAM212A 35
  • 63.06 (n)
  • 56.76 (a)
(Anolis carolinensis)
Reptilia FAM212A 36
  • 35 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam212a 35
  • 52.2 (n)
  • 43.8 (a)
(Danio rerio)
Actinopterygii fam212ab 35
  • 49.66 (n)
  • 46.46 (a)
wufi03b07 35
fam212aa 36
  • 31 (a)
fam212ab 36
  • 32 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4864 35
Species with no ortholog for FAM212A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM212A Gene

Gene Tree for FAM212A (if available)
Gene Tree for FAM212A (if available)

Paralogs for FAM212A Gene

Paralogs for FAM212A Gene

genes like me logo Genes that share paralogs with FAM212A: view

Variants for FAM212A Gene

Variation tolerance for FAM212A Gene

Residual Variation Intolerance Score: 61.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.97; 20.10% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM212A Gene

Disorders for FAM212A Gene

Relevant External Links for FAM212A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM212A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM212A Gene

Publications for FAM212A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. (PMID: 20175189) Reid B.S. … Williams T. (Dev. Dyn. 2010) 3

Products for FAM212A Gene

Sources for FAM212A Gene