FAM211B Gene
protein-coding GIFtS: 35
GCID: GC22M024982
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family with sequence similarity 211, member B(Previous name: chromosome 22 open reading frame 36 )
(Previous symbol: C22orf36)
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Aliases
for FAM211B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 211, Member B1 2 | | C22orf361 2 3 | | MGC1317731 | | Chromosome 22 Open Reading Frame 361 | | Leucine-Rich Repeat-Containing Protein C22orf362 | | Leucine-Rich Repeat-Containing Protein FAM211B2 |
Export aliases for FAM211B gene to outside databases |
Summaries
for FAM211B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
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Genomic Views
for FAM211B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM211B
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM211B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM211B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.23 Ensembl cytogenetic band: 22q11.23 HGNC cytogenetic band: 22q11.23FAM211B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M024982: view genomic region
(about GC identifiers)
Start:
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24,981,588 bp from pter |
End:
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24,989,175 bp from pter |
Size:
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7,588 bases |
Orientation:
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minus strand |
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Proteins
for FAM211B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F211B_HUMAN, Q2VPJ9 (See
protein sequence)Recommended Name: Leucine-rich repeat-containing protein FAM211B Size: 315 amino acids; 34740 Da
Secondary accessions: Q8N0S9 Q8N8B1Alternative splicing: 2 isoforms: Q2VPJ9-1 Q2VPJ9-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM211B: NX_Q2VPJ9
FAM211B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_997527.2
ENSEMBL proteins: ENSP00000320520 ENSP00000400102 ENSP00000384130
Human Recombinant Protein Products:
FAM211B Antibody Products:
Assay Products for FAM211B: |
Protein
Domains /
Families
for FAM211B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q2VPJ9 1 Blocks protein family: IPB001611 Leucine-rich repeat signature
UniProtKB/Swiss-Prot: F211B_HUMAN, Q2VPJ9Similarity: Belongs to the FAM211 familySimilarity: Contains 2 LRR (leucine-rich) repeats |
Function
for FAM211B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM211B | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM211B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM211B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211B |
1 GenomeRNAi human phenotype for FAM211B:
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Pathways & Interactions
for FAM211B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM211B
|
Drugs & Compounds
for FAM211B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM211B
Search CenterWatch for drugs/clinical trials and news about FAM211B / F211B
|
Transcripts
for FAM211B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM211B gene: NM_207644.2 Unigene Cluster for FAM211B: Family with sequence similarity 211, member B Hs.113314 [show with all ESTs]Unigene Representative Sequence: AK0970548 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000318753 ENST00000446942(uc003aao.2 uc003aaq.2) ENST00000491910
ENST00000404045 ENST00000460524 ENST00000495297 ENST00000465334 ENST00000464490
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM211B | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM211B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM211B |
Additional cDNA sequence: AK097054.1 BC017595.1 BC032388.1 BC108684.1 16 DOTS entries: DT.95228550 DT.120642611 DT.100776090 DT.100776089 DT.100768826 DT.120642778 DT.100670087 DT.100771068 DT.120642531 DT.91800185 DT.70102112 DT.100712026 DT.100732909 DT.100759339 DT.120642897 DT.100863856 24/85 AceView cDNA sequences (see all 85): BC032388 CR614356 BE255471 BM971987 AI669102 BU616633 BM715883 BX368809 AI810832 CR613314 BU728854 BM674209 BC017595 NM_207644 BM725261 AK097054 AI201981 BQ932323 BM727589 BX338904 BU681641 AW006520 AI082195 BU189997
GeneLoc Exon Structure
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Expression
for FAM211B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM211B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGCTGTGCT
About this image
See FAM211B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM211B
SOURCE GeneReport for Unigene cluster: Hs.113314
SABiosciences Custom PCR Arrays for FAM211B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM211B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM211B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM211B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM211B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211B |
Orthologs
for FAM211B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for FAM211B gene from 3/6 species (see all 6) About this table
ENSEMBL Gene Tree for FAM211B (if available)
TreeFam Gene Tree for FAM211B (if available) |
Paralogs
for FAM211B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM211B gene
- FAM211A2
1 SIMAP similar gene for FAM211B using alignment to 3 protein entries: F211B_HUMAN (see all proteins):FAM211A
FAM211B for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FAM211B
PGOHUM00000235040
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Genomic Variants
for FAM211B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM211B |
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Disorders
/ Diseases
for FAM211B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM211B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM211B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM211B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Large-scale genome-wide association studies in East As ians identify new genetic loci influencing metabolic traits. (PubMed id 21909109)1 Kim Y.J....Cho Y.S. (2011)
- Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. (PubMed id 18940312)1 Yuan X....Mooser V. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM211B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM211B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing FAM211B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM211B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM211B | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM211B gene:
Search GeneIP for patents involving FAM211B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM211B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | Browse OriGene 29mer shRNA kits in GFP-retroviral vector | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM211B | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for FAM211B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM211B | | OriGene Custom Protein Services for FAM211B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM211B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM211B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM211B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM211B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM211B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM211B |
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| | | | Search Tocris compounds for FAM211B |
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 | | | FAM211B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211B |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM211B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM211B |
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