FAM211A Gene
protein-coding GIFtS: 35
GCID: GC17M016344
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|
family with sequence similarity 211, member A(Previous name: chromosome 17 open reading frame 76 )
(Previous symbol: C17orf76)
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Aliases
for FAM211A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 211, Member A1 2 | | C17orf761 2 3 | | FLJ356961 | | Chromosome 17 Open Reading Frame 761 | | Leucine-Rich Repeat-Containing Protein C17orf762 | | Leucine-Rich Repeat-Containing Protein FAM211A2 |
Export aliases for FAM211A gene to outside databases |
Summaries
for FAM211A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM211A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM211A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM211A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM211A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2FAM211A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M016344: view genomic region
(about GC identifiers)
Start:
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16,344,891 bp from pter |
End:
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16,395,480 bp from pter |
Size:
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50,590 bases |
Orientation:
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minus strand |
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Proteins
for FAM211A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F211A_HUMAN, Q8NAA5 (See
protein sequence)Recommended Name: Leucine-rich repeat-containing protein FAM211A Size: 344 amino acids; 37780 DaAlternative splicing: 2 isoforms: Q8NAA5-1 Q8NAA5-2 Explore the universe of human proteins at neXtProt for FAM211A: NX_Q8NAA5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8NAA5
FAM211A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001107039.1 NP_997270.2
ENSEMBL proteins: ENSP00000386504 ENSP00000419502
Human Recombinant Protein Products:
FAM211A Antibody Products:
Assay Products for FAM211A: |
Protein
Domains /
Families
for FAM211A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q8NAA5 UniProtKB/Swiss-Prot: F211A_HUMAN, Q8NAA5Similarity: Belongs to the FAM211 familySimilarity: Contains 2 LRR (leucine-rich) repeats |
Function
for FAM211A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM211A | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM211A | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM211A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211A |
|
Pathways & Interactions
for FAM211A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM211A
|
Drugs & Compounds
for FAM211A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM211A
Search CenterWatch for drugs/clinical trials and news about FAM211A / F211A
|
Transcripts
for FAM211A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM211A gene (2 alternative transcripts): NM_001113567.2 NM_207387.3 Unigene Cluster for FAM211A: Family with sequence similarity 211, member A Hs.25425 [show with all ESTs]Unigene Representative Sequence: AL8332603 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000409887(uc002gqg.1) ENST00000409083(uc010cph.1 uc002gqh.2)
ENST00000470794
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM211A | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM211A | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM211A |
Additional cDNA sequence: AK093015.1 AL833245.1 AL833260.1 BC144381.1 12 DOTS entries: DT.99926865 DT.97869724 DT.97856848 DT.91952129 DT.100801729 DT.319178 DT.91781339 DT.120965696 DT.120965754 DT.426333 DT.91781349 DT.91781357 24/107 AceView cDNA sequences (see all 107): W70271 AW136144 W94998 Z45331 AA365207 W93383 Z41045 AA188879 BX434642 AA974741 AA927004 AW163092 BE855931 BX483667 AL833245 AI298679 AL833260 AI339689 AI298465 NM_207387 W67256 AI951996 AI282360 AI801402
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM211A About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b |
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| SP1: | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for FAM211A
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Expression
for FAM211A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM211A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGGCAAGGG
About this image
See FAM211A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM211A
SOURCE GeneReport for Unigene cluster: Hs.25425
SABiosciences Custom PCR Arrays for FAM211A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM211A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM211A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM211A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM211A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211A |
Orthologs
for FAM211A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM211A gene from 3/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM211A1 |
family with sequence similarity 211, member A |
70.48(n)
69.5(a) |
|
417550 XM_415798.2 XP_415798.2 |
lizard
(Anolis carolinensis) |
Reptilia |
C17orf766 |
-- |
61(a) |
1 ↔ 1 |
GL344964.1(2795-7468) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC5629361 |
leucine-rich repeat-containing protein C17orf76-like |
69.21(n)
69.21(a) |
|
562936 XM_686301.2 XP_691393.2 |
ENSEMBL Gene Tree for FAM211A (if available)
TreeFam Gene Tree for FAM211A (if available) |
Paralogs
for FAM211A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM211A gene
- FAM211B2
1 SIMAP similar gene for FAM211A using alignment to 1 protein entry: F211A_HUMAN:FAM211B
FAM211A for paralogs About GeneDecksing
|
Genomic Variants
for FAM211A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM211A (16344891 - 16395480 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM211A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM211A |
|
Disorders
/ Diseases
for FAM211A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM211A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM211A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM211A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2, 3 Ota T.... Sugano S. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM211A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM211A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM211A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM211A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM211A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM211A gene:
Search GeneIP for patents involving FAM211A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM211A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM211A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM211A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM211A | | | OriGene Protein Over-expression Lysate for FAM211A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM211A | | OriGene 3'-UTR Clone for FAM211A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM211A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM211A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM211A | | OriGene Custom Protein Services for FAM211A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM211A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM211A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM211A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM211A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM211A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM211A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM211A |
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 | | | FAM211A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM211A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM211A |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM211A |
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