FAM210B Gene
protein-coding GIFtS: 37
GCID: GC20P054934
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family with sequence similarity 210, member B(Previous name: chromosome 20 open reading frame 108 )
(Previous symbol: C20orf108)
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Aliases
for FAM210B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 210, Member B1 2 | | Chromosome 20 Open Reading Frame 1081 | | C20orf1081 2 3 | | 5A32 | | DJ1167H4.11 | | Protein FAM210B2 | | DKFZP434A11141 | | Transmembrane Protein C20orf1082 |
Export aliases for FAM210B gene to outside databases |
Summaries
for FAM210B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM210B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011362.10
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM210B
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM210B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM210B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20q13.2 Ensembl cytogenetic band: 20q13.2 HGNC cytogenetic band: 20q13.2FAM210B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P054934: view genomic region
(about GC identifiers)
Start:
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54,933,971 bp from pter |
End:
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54,943,719 bp from pter |
Size:
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9,749 bases |
Orientation:
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plus strand |
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Proteins
for FAM210B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F210B_HUMAN, Q96KR6 (See
protein sequence)Recommended Name: Protein FAM210B Size: 192 amino acids; 20424 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: B2RBQ9 E1P5Y7 Q8WVN2 Q9BYL6 Q9H418Explore the universe of human proteins at neXtProt for FAM210B: NX_Q96KR6
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96KR6
FAM210B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_543011.2
ENSEMBL proteins: ENSP00000360437 ENSP00000389768
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
FAM210B for ontologies About GeneDecksing
FAM210B Antibody Products:
Assay Products for FAM210B: |
Protein
Domains /
Families
for FAM210B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM210B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96KR6ProtoNet protein and cluster: Q96KR6 UniProtKB/Swiss-Prot: F210B_HUMAN, Q96KR6Similarity: Belongs to the FAM210 familySimilarity: Contains 1 DUF1279 domain |
Function
for FAM210B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM210B | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM210B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM210B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM210B |
|
Pathways & Interactions
for FAM210B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM210B
|
Drugs & Compounds
for FAM210B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM210B
Search CenterWatch for drugs/clinical trials and news about FAM210B / F210B
|
Transcripts
for FAM210B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM210B gene: NM_080821.2 Unigene Clusters for FAM210B: Family with sequence similarity 210, member B Hs.143736 [show with all ESTs], Hs.593629 [show with all ESTs]Unigene Representative Sequences: NM_080821, BG0332622 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000371384(uc002xxc.3) ENST00000437418
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM210B | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM210B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM210B |
Additional cDNA sequence: L17329.1 8 DOTS entries: DT.91927494 DT.100727398 DT.102830257 DT.99977637 DT.101975029 DT.120806896 DT.120806898 DT.92431794 24/312 AceView cDNA sequences (see all 312): BU782813 BU740658 F37064 BQ679538 BU161746 BQ879066 AA417273 BM311639 BQ431501 BM459828 BM797036 AA515563 BM675243 AA576226 AI818756 BM990513 AL120698 CB157165 AA642407 AA977629 AA872841 AI032936 AI871571 BU156236
GeneLoc Exon Structure
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Expression
for FAM210B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM210B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTTTACAC
About this image
See FAM210B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM210B
SOURCE GeneReport for Unigene clusters: Hs.143736 Hs.593629
SABiosciences Custom PCR Arrays for FAM210B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM210B
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM210B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM210B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM210B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM210B |
Orthologs
for FAM210B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FAM210B gene from 6/20 species (see all 20) About this table
ENSEMBL Gene Tree for FAM210B (if available)
TreeFam Gene Tree for FAM210B (if available) |
Paralogs
for FAM210B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM210B gene
- FAM210A2
FAM210B for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FAM210B
PGOHUM00000238380 PGOHUM00000260621
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Genomic Variants
for FAM210B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM210B (54933971 - 54943719 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM210B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM210B |
|
Disorders
/ Diseases
for FAM210B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM210B for disorders About GeneDecksing
2  diseases for FAM210B: About MalaCardsepithelial ovarian cancer ovarian cancer
Export disorders for FAM210B gene to outside databases
|
Publications
for FAM210B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM210B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM210B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2, 3 Deloukas P....Rogers J. (2001)
- Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PubMed id 19064572)1 Palmieri R.T.... . (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
- Identification of human pre-T/NK cell-associated genes. (PubMed id 8228263)1 Ranes-Goldberg M.G.... Spits H. (1993)
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External Searches for FAM210B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM210B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM210B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM210B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM210B | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM210B gene:
Search GeneIP for patents involving FAM210B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM210B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM210B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM210B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM210B | | | OriGene Protein Over-expression Lysate for FAM210B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM210B | | OriGene 3'-UTR Clone for FAM210B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM210B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM210B | | OriGene Custom Protein Services for FAM210B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM210B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM210B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM210B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM210B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM210B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM210B |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM210B |
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 | | | FAM210B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM210B |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM210B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM210B |
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