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Aliases for FAM210B Gene

Aliases for FAM210B Gene

  • Family With Sequence Similarity 210 Member B 2 3 5
  • Family With Sequence Similarity 210, Member B 2 3
  • C20orf108 3 4
  • Chromosome 20 Open Reading Frame 108 2
  • Transmembrane Protein C20orf108 3
  • Hypothetical Protein LOC116151 2
  • DJ1167H4.1 3
  • 5A3 3

External Ids for FAM210B Gene

Previous HGNC Symbols for FAM210B Gene

  • C20orf108

Previous GeneCards Identifiers for FAM210B Gene

  • GC20P054934

Summaries for FAM210B Gene

GeneCards Summary for FAM210B Gene

FAM210B (Family With Sequence Similarity 210 Member B) is a Protein Coding gene. An important paralog of this gene is FAM210A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM210B Gene

Genomics for FAM210B Gene

Regulatory Elements for FAM210B Gene

Promoters for FAM210B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM210B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM210B Gene

Chromosome:
20
Start:
56,358,915 bp from pter
End:
56,368,663 bp from pter
Size:
9,749 bases
Orientation:
Plus strand

Genomic View for FAM210B Gene

Genes around FAM210B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM210B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM210B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM210B Gene

Proteins for FAM210B Gene

  • Protein details for FAM210B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KR6-F210B_HUMAN
    Recommended name:
    Protein FAM210B
    Protein Accession:
    Q96KR6
    Secondary Accessions:
    • B2RBQ9
    • E1P5Y7
    • Q8WVN2
    • Q9BYL6
    • Q9H418

    Protein attributes for FAM210B Gene

    Size:
    192 amino acids
    Molecular mass:
    20424 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM210B Gene

Proteomics data for FAM210B Gene at MOPED

Post-translational modifications for FAM210B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM210B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM210B Gene

Domains & Families for FAM210B Gene

Protein Domains for FAM210B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM210B Gene

Graphical View of Domain Structure for InterPro Entry

Q96KR6

UniProtKB/Swiss-Prot:

F210B_HUMAN :
  • Contains 1 DUF1279 domain.
  • Belongs to the FAM210 family.
Domain:
  • Contains 1 DUF1279 domain.
Family:
  • Belongs to the FAM210 family.
genes like me logo Genes that share domains with FAM210B: view

No data available for Gene Families for FAM210B Gene

Function for FAM210B Gene

Phenotypes for FAM210B Gene

genes like me logo Genes that share phenotypes with FAM210B: view

Animal Model Products

CRISPR Products

miRNA for FAM210B Gene

miRTarBase miRNAs that target FAM210B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM210B Gene

Localization for FAM210B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM210B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM210B Gene COMPARTMENTS Subcellular localization image for FAM210B gene
Compartment Confidence
plasma membrane 3
cytosol 2
extracellular 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for FAM210B Gene

Pathways & Interactions for FAM210B Gene

SuperPathways for FAM210B Gene

No Data Available

Interacting Proteins for FAM210B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000360437%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000360437 for FAM210B Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for FAM210B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM210B Gene

Drugs & Compounds for FAM210B Gene

No Compound Related Data Available

Transcripts for FAM210B Gene

mRNA/cDNA for FAM210B Gene

Unigene Clusters for FAM210B Gene

Family with sequence similarity 210, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM210B Gene

No ASD Table

Relevant External Links for FAM210B Gene

GeneLoc Exon Structure for
FAM210B
ECgene alternative splicing isoforms for
FAM210B

Expression for FAM210B Gene

mRNA expression in normal human tissues for FAM210B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM210B Gene

This gene is overexpressed in Whole Blood (x4.8).

Protein differential expression in normal tissues from HIPED for FAM210B Gene

This gene is overexpressed in Hair follicle (12.4) and Adrenal (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for FAM210B Gene



SOURCE GeneReport for Unigene cluster for FAM210B Gene Hs.143736

genes like me logo Genes that share expression patterns with FAM210B: view

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM210B Gene

Orthologs for FAM210B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM210B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM210B 35
  • 83.85 (n)
  • 83.33 (a)
C13H20ORF108 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM210B 35
  • 85.24 (n)
  • 81.25 (a)
FAM210B 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam210b 35
  • 77.54 (n)
  • 77.37 (a)
Fam210b 16
Fam210b 36
  • 77 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM210B 35
  • 98.96 (n)
  • 98.44 (a)
FAM210B 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam210b 35
  • 76.49 (n)
  • 77.37 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM210B 36
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM210B 36
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves C20H20ORF108 35
  • 67.15 (n)
  • 68.84 (a)
C20H20ORF108 36
  • 70 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM210B 36
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam210b 35
  • 60.31 (n)
  • 57.8 (a)
Str.15729 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.18665 35
zebrafish
(Danio rerio)
Actinopterygii fam210b 36
  • 38 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG15403 36
  • 33 (a)
OneToMany
CG17508 36
  • 21 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6707 36
  • 25 (a)
OneToOne
Species with no ortholog for FAM210B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM210B Gene

ENSEMBL:
Gene Tree for FAM210B (if available)
TreeFam:
Gene Tree for FAM210B (if available)

Paralogs for FAM210B Gene

Paralogs for FAM210B Gene

Pseudogenes.org Pseudogenes for FAM210B Gene

genes like me logo Genes that share paralogs with FAM210B: view

Variants for FAM210B Gene

Sequence variations from dbSNP and Humsavar for FAM210B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs6099115 - 56,366,084(+) ACATG(C/T)CTGCA reference, missense
rs12150 -- 56,368,476(+) TCTCT(C/G)CTAAG utr-variant-3-prime
rs13872 -- 56,368,089(-) TCTAC(A/C)TGAAA utr-variant-3-prime
rs14497 -- 56,366,955(-) AGAGA(C/G)AAATG utr-variant-3-prime
rs1044377 -- 56,366,849(+) AAGTA(G/T)TTCTG utr-variant-3-prime

Variation tolerance for FAM210B Gene

Residual Variation Intolerance Score: 44.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.96; 83.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM210B Gene

HapMap Linkage Disequilibrium report
FAM210B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM210B Gene

Disorders for FAM210B Gene

Relevant External Links for FAM210B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM210B

No disorders were found for FAM210B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM210B Gene

Publications for FAM210B Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PMID: 19064572) Palmieri R.T. … . (Cancer Epidemiol. Biomarkers Prev. 2008) 3
  5. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3

Products for FAM210B Gene

Sources for FAM210B Gene

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