Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM210B Gene

Aliases for FAM210B Gene

  • Family With Sequence Similarity 210, Member B 2 3
  • C20orf108 3 4
  • Chromosome 20 Open Reading Frame 108 2
  • Transmembrane Protein C20orf108 3
  • Hypothetical Protein LOC116151 2
  • DJ1167H4.1 3
  • 5A3 3

External Ids for FAM210B Gene

Previous HGNC Symbols for FAM210B Gene

  • C20orf108

Previous GeneCards Identifiers for FAM210B Gene

  • GC20P054934

Summaries for FAM210B Gene

GeneCards Summary for FAM210B Gene

FAM210B (Family With Sequence Similarity 210, Member B) is a Protein Coding gene. An important paralog of this gene is FAM210A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM210B Gene

Genomics for FAM210B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM210B Gene

56,358,915 bp from pter
56,368,663 bp from pter
9,749 bases
Plus strand

Genomic View for FAM210B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM210B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM210B Gene

No data available for Regulatory Elements for FAM210B Gene

Proteins for FAM210B Gene

  • Protein details for FAM210B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM210B
    Protein Accession:
    Secondary Accessions:
    • B2RBQ9
    • E1P5Y7
    • Q8WVN2
    • Q9BYL6
    • Q9H418

    Protein attributes for FAM210B Gene

    192 amino acids
    Molecular mass:
    20424 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM210B Gene

Proteomics data for FAM210B Gene at MOPED

Post-translational modifications for FAM210B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM210B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM210B Gene

Domains & Families for FAM210B Gene

Protein Domains for FAM210B Gene


Suggested Antigen Peptide Sequences for FAM210B Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 DUF1279 domain.
  • Belongs to the FAM210 family.
  • Contains 1 DUF1279 domain.
  • Belongs to the FAM210 family.
genes like me logo Genes that share domains with FAM210B: view

No data available for Gene Families for FAM210B Gene

Function for FAM210B Gene

Phenotypes for FAM210B Gene

GenomeRNAi human phenotypes for FAM210B:
genes like me logo Genes that share phenotypes with FAM210B: view

Animal Model Products

CRISPR Products

miRNA for FAM210B Gene

miRTarBase miRNAs that target FAM210B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM210B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM210B Gene

Localization for FAM210B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM210B Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FAM210B Gene COMPARTMENTS Subcellular localization image for FAM210B gene
Compartment Confidence
cytosol 2
plasma membrane 2

Gene Ontology (GO) - Cellular Components for FAM210B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM210B: view

Pathways & Interactions for FAM210B Gene

SuperPathways for FAM210B Gene

No Data Available

Interacting Proteins for FAM210B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000360437 for FAM210B Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM210B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM210B Gene

Drugs & Compounds for FAM210B Gene

No Compound Related Data Available

Transcripts for FAM210B Gene

mRNA/cDNA for FAM210B Gene

Unigene Clusters for FAM210B Gene

Family with sequence similarity 210, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM210B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM210B Gene

No ASD Table

Relevant External Links for FAM210B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM210B Gene

mRNA expression in normal human tissues for FAM210B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM210B Gene

This gene is overexpressed in Whole Blood (x4.8).

Protein differential expression in normal tissues from HIPED for FAM210B Gene

This gene is overexpressed in Hair follicle (12.4) and Adrenal (10.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM210B Gene

SOURCE GeneReport for Unigene cluster for FAM210B Gene Hs.143736

genes like me logo Genes that share expression patterns with FAM210B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM210B Gene

Orthologs for FAM210B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM210B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM210B 35
  • 83.85 (n)
  • 83.33 (a)
C13H20ORF108 36
  • 83 (a)
(Canis familiaris)
Mammalia FAM210B 35
  • 85.24 (n)
  • 81.25 (a)
FAM210B 36
  • 81 (a)
(Mus musculus)
Mammalia Fam210b 35
  • 77.54 (n)
  • 77.37 (a)
Fam210b 16
Fam210b 36
  • 77 (a)
(Pan troglodytes)
Mammalia FAM210B 35
  • 98.96 (n)
  • 98.44 (a)
FAM210B 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam210b 35
  • 76.49 (n)
  • 77.37 (a)
(Monodelphis domestica)
Mammalia FAM210B 36
  • 58 (a)
(Ornithorhynchus anatinus)
Mammalia FAM210B 36
  • 73 (a)
(Gallus gallus)
Aves C20H20ORF108 35
  • 67.15 (n)
  • 68.84 (a)
C20H20ORF108 36
  • 70 (a)
(Anolis carolinensis)
Reptilia FAM210B 36
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam210b 35
  • 60.31 (n)
  • 57.8 (a)
Str.15729 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.18665 35
(Danio rerio)
Actinopterygii fam210b 36
  • 38 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG15403 36
  • 33 (a)
CG17508 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6707 36
  • 25 (a)
Species with no ortholog for FAM210B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM210B Gene

Gene Tree for FAM210B (if available)
Gene Tree for FAM210B (if available)

Paralogs for FAM210B Gene

Paralogs for FAM210B Gene Pseudogenes for FAM210B Gene

genes like me logo Genes that share paralogs with FAM210B: view

Variants for FAM210B Gene

Sequence variations from dbSNP and Humsavar for FAM210B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs12150 -- 56,368,476(+) TCTCT(C/G)CTAAG utr-variant-3-prime
rs13872 -- 56,368,089(-) TCTAC(A/C)TGAAA utr-variant-3-prime
rs14497 -- 56,366,955(-) AGAGA(C/G)AAATG utr-variant-3-prime
rs1044377 -- 56,366,849(+) AAGTA(G/T)TTCTG utr-variant-3-prime
rs2012397 -- 56,356,950(+) GAGGC(G/T)GAGGT upstream-variant-2KB

Variation tolerance for FAM210B Gene

Residual Variation Intolerance Score: 44.61% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.96; 83.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM210B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM210B Gene

Disorders for FAM210B Gene

Relevant External Links for FAM210B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM210B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM210B Gene

Publications for FAM210B Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  5. Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PMID: 19064572) Palmieri R.T. … . (Cancer Epidemiol. Biomarkers Prev. 2008) 67

Products for FAM210B Gene

Sources for FAM210B Gene

Back to Top