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Aliases for FAM210A Gene

Aliases for FAM210A Gene

  • Family With Sequence Similarity 210 Member A 2 3 5
  • C18orf19 3 4
  • Family With Sequence Similarity 210, Member A 2
  • Chromosome 18 Open Reading Frame 19 2
  • Uncharacterized Protein C18orf19 3
  • Protein FAM210A 3
  • HsT2329 3

External Ids for FAM210A Gene

Previous HGNC Symbols for FAM210A Gene

  • C18orf19

Summaries for FAM210A Gene

GeneCards Summary for FAM210A Gene

FAM210A (Family With Sequence Similarity 210 Member A) is a Protein Coding gene. An important paralog of this gene is FAM210B.

Additional gene information for FAM210A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM210A Gene

Genomics for FAM210A Gene

GeneHancer (GH) Regulatory Elements for FAM210A Gene

Promoters and enhancers for FAM210A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH18I013725 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 555.2 +0.0 3 3.2 PKNOX1 CLOCK MLX ARID4B SIN3A DMAP1 ZNF2 IRF4 YY1 SLC30A9 RNMT FAM210A PTPN2 CEP192
GH18I013700 Promoter 0.5 EPDnew 550.3 +26.0 25993 0.1 FAM210A ENSG00000279962 ENSG00000266954
GH18I013562 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 2.7 +163.2 163246 2.8 HDGF PKNOX1 RB1 BMI1 BATF KLF5 IRF4 ATF7 ETV6 IKZF2 ENSG00000267503 PIR42063 LDLRAD4 PSMG2 FAM210A RNMT
GH18I013610 Promoter/Enhancer 2.1 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 1.8 +112.9 112909 6.6 HDGF PKNOX1 SMAD1 SIN3A BMI1 BATF KLF5 IRF4 SCRT2 ZNF207 LDLRAD4 RNMT FAM210A MIR4526 ENSG00000266954
GH18I013576 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 2.3 +149.0 149031 2.5 SMAD1 BATF RAD21 KLF5 IRF4 ZNF207 ATF7 ETV6 BCLAF1 IKZF2 LDLRAD4 RNMT FAM210A ENSG00000267503 MIR4526
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FAM210A on UCSC Golden Path with GeneCards custom track

Genomic Locations for FAM210A Gene

Genomic Locations for FAM210A Gene
chr18:13,663,347-13,726,663
(GRCh38/hg38)
Size:
63,317 bases
Orientation:
Minus strand
chr18:13,663,346-13,726,662
(GRCh37/hg19)

Genomic View for FAM210A Gene

Genes around FAM210A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM210A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM210A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM210A Gene

Proteins for FAM210A Gene

  • Protein details for FAM210A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96ND0-F210A_HUMAN
    Recommended name:
    Protein FAM210A
    Protein Accession:
    Q96ND0
    Secondary Accessions:
    • D3DUJ4

    Protein attributes for FAM210A Gene

    Size:
    272 amino acids
    Molecular mass:
    30777 Da
    Quaternary structure:
    • Interacts with ATAD3A.

neXtProt entry for FAM210A Gene

Post-translational modifications for FAM210A Gene

No Post-translational modifications

Other Protein References for FAM210A Gene

No data available for DME Specific Peptides for FAM210A Gene

Domains & Families for FAM210A Gene

Gene Families for FAM210A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for FAM210A Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q96ND0

UniProtKB/Swiss-Prot:

F210A_HUMAN :
  • Belongs to the FAM210 family.
Family:
  • Belongs to the FAM210 family.
genes like me logo Genes that share domains with FAM210A: view

No data available for Suggested Antigen Peptide Sequences for FAM210A Gene

Function for FAM210A Gene

Phenotypes From GWAS Catalog for FAM210A Gene

Phenotypes for FAM210A Gene

MGI mutant phenotypes for FAM210A:
inferred from 1 alleles
GenomeRNAi human phenotypes for FAM210A:
genes like me logo Genes that share phenotypes with FAM210A: view

Animal Models for FAM210A Gene

MGI Knock Outs for FAM210A:

Animal Model Products

miRNA for FAM210A Gene

miRTarBase miRNAs that target FAM210A

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FAM210A Gene

Localization for FAM210A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM210A Gene

Membrane; Single-pass membrane protein. Mitochondrion.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM210A gene
Compartment Confidence
mitochondrion 5
nucleus 2
golgi apparatus 2
peroxisome 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (2)
  • Mitochondria (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for FAM210A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM210A: view

Pathways & Interactions for FAM210A Gene

SuperPathways for FAM210A Gene

No Data Available

Interacting Proteins for FAM210A Gene

Gene Ontology (GO) - Biological Process for FAM210A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM210A Gene

Drugs & Compounds for FAM210A Gene

No Compound Related Data Available

Transcripts for FAM210A Gene

Unigene Clusters for FAM210A Gene

Family with sequence similarity 210, member A:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM210A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c
SP1:
SP2: -
SP3: - - -

Relevant External Links for FAM210A Gene

GeneLoc Exon Structure for
FAM210A
ECgene alternative splicing isoforms for
FAM210A

Expression for FAM210A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM210A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for FAM210A Gene

This gene is overexpressed in Pancreas (7.9), Bone (7.8), and Adrenal (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM210A Gene



Protein tissue co-expression partners for FAM210A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM210A Gene:

FAM210A

SOURCE GeneReport for Unigene cluster for FAM210A Gene:

Hs.13034
genes like me logo Genes that share expression patterns with FAM210A: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM210A Gene

Orthologs for FAM210A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM210A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM210A 33 34
  • 99.88 (n)
dog
(Canis familiaris)
Mammalia FAM210A 34 33
  • 87.62 (n)
OneToOne
cow
(Bos Taurus)
Mammalia FAM210A 33 34
  • 84.56 (n)
rat
(Rattus norvegicus)
Mammalia Fam210a 33
  • 81.62 (n)
mouse
(Mus musculus)
Mammalia Fam210a 33 16 34
  • 80.51 (n)
oppossum
(Monodelphis domestica)
Mammalia FAM210A 34
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM210A 34
  • 67 (a)
OneToOne
chicken
(Gallus gallus)
Aves C2H18ORF19 33
  • 69.77 (n)
FAM210A 34
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM210A 34
  • 53 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam210a 33
  • 62.98 (n)
Str.9203 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.7564 33
zebrafish
(Danio rerio)
Actinopterygii si:ch211-105d11.2 33
  • 69.3 (n)
FAM210A (1 of 2) 34
  • 50 (a)
OneToMany
fam210a 34
  • 45 (a)
OneToMany
wufi06g08 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4600 33
fruit fly
(Drosophila melanogaster)
Insecta CG14613 34
  • 28 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea Y56A3A.22 34
  • 20 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 24 (a)
OneToOne
Species where no ortholog for FAM210A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM210A Gene

ENSEMBL:
Gene Tree for FAM210A (if available)
TreeFam:
Gene Tree for FAM210A (if available)

Paralogs for FAM210A Gene

Variants for FAM210A Gene

Sequence variations from dbSNP and Humsavar for FAM210A Gene

SNP ID Clin Chr 18 pos Variation AA Info Type
rs116967198 A breast cancer sample 13,681,833(-) C/A/T coding_sequence_variant, missense_variant
VAR_035687 A breast cancer sample p.Val140Glu
rs1000015528 -- 13,666,012(-) C/T 3_prime_UTR_variant
rs1000073485 -- 13,686,266(-) G/A intron_variant
rs1000136170 -- 13,714,328(-) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for FAM210A Gene

Variant ID Type Subtype PubMed ID
esv1001818 CNV loss 20482838
esv1025327 CNV deletion 17803354
esv1105405 CNV deletion 17803354
esv1408829 CNV deletion 17803354
esv1692955 CNV deletion 17803354
esv1773722 CNV deletion 17803354
esv2716822 CNV deletion 23290073
esv28578 CNV loss 19812545
nsv1071433 CNV deletion 25765185
nsv576529 CNV gain 21841781
nsv821605 CNV deletion 20802225

Variation tolerance for FAM210A Gene

Residual Variation Intolerance Score: 37.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.44; 9.70% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FAM210A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM210A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM210A Gene

Disorders for FAM210A Gene

Additional Disease Information for FAM210A

No disorders were found for FAM210A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM210A Gene

Publications for FAM210A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. An organelle-specific protein landscape identifies novel diseases and molecular mechanisms. (PMID: 27173435) Boldt K … UK10K Rare Diseases Group (Nature communications 2016) 3 58
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58
  5. Gene essentiality and synthetic lethality in haploid human cells. (PMID: 26472760) Blomen VA … Brummelkamp TR (Science (New York, N.Y.) 2015) 3 58

Products for FAM210A Gene

Sources for FAM210A Gene

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