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FAM20C Gene

protein-coding   GIFtS: 57
GCID: GC07P000290

Family With Sequence Similarity 20, Member C

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 20, Member C1 2     GEF-CK2 3
Dentin Matrix Protein 41 2 3     RNS2
DMP42 3 5     Extracellular Serine/Threonine Protein Kinase FAM20C2
Golgi-Enriched Fraction Casein Kinase2 3     EC 2.7.11.13
DMP-42 3     Protein FAM20C3

External Ids:    HGNC: 221401   Entrez Gene: 569752   Ensembl: ENSG000001777067   OMIM: 6110615   UniProtKB: Q8IXL63   

Export aliases for FAM20C gene to outside databases

Previous GC identifers: GC07U900326 GC07P000276 GC07P000289


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FAM20C Gene:
This gene encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. A
similar gene in mice encodes a protein that plays a role in dentin mineralization, and mutations in the human
gene are associated with the autosomal recessive disorder Raine syndrome. (provided by RefSeq, Nov 2011)

GeneCards Summary for FAM20C Gene:
FAM20C (family with sequence similarity 20, member C) is a protein-coding gene. Diseases associated with FAM20C include raine syndrome, and hcl-v. GO annotations related to this gene include protein serine/threonine kinase activity and calcium ion binding. An important paralog of this gene is FAM20A.

UniProtKB/Swiss-Prot: DMP4_HUMAN, Q8IXL6
Function: Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in
biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates
its targets within the S-x-E/pS motif

Gene Wiki entry for FAM20C Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007819.18  NC_018918.2  NT_187558.1  NT_187653.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM20C gene promoter:
         Pax-5   HOXA3   LCR-F1   AREB6   MEF-2A   FAC1   Sox9   aMEF-2   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM20C promoter sequence
   Search Chromatin IP Primers for FAM20C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM20C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.3   Ensembl cytogenetic band:  7p22.3   HGNC cytogenetic band: 7p22.3

FAM20C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM20C gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P000290:  view genomic region     (about GC identifiers)

Start:
192,969 bp from pter      End:
300,711 bp from pter
Size:
107,743 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 303,573-364,779     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: DMP4_HUMAN, Q8IXL6 (See protein sequence)
Recommended Name: Extracellular serine/threonine protein kinase FAM20C precursor  
Size: 584 amino acids; 66234 Da
Sequence caution: Sequence=AAH40074.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=EAL23705.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A4D2Q5 L8B5W8 Q5I0W9 Q7Z4I0 Q9NPT2
Alternative splicing: 2 isoforms:  Q8IXL6-1   Q8IXL6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM20C: NX_Q8IXL6

Explore proteomics data for FAM20C at MOPED

Post-translational modifications: 

  • Glycosylation2 at Ser41, Ser47, Ser74, Ser75, Thr87, Asn101, Ser148, Ser150, Asn335, Asn470
  • Modification sites at PhosphoSitePlus

  • See FAM20C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_064608.2  
    ENSEMBL proteins: 
     ENSP00000322323  

    FAM20C Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for FAM20C
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    Cloud-Clone Corp. CLIAs for FAM20C


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR009581 DUF1193
     IPR024869 FAM20

    Graphical View of Domain Structure for InterPro Entry Q8IXL6

    ProtoNet protein and cluster: Q8IXL6

    1 Blocks protein domain: IPB009581 Protein of unknown function DUF1193

    UniProtKB/Swiss-Prot: DMP4_HUMAN, Q8IXL6
    Similarity: Belongs to the FAM20 family


    FAM20C for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: DMP4_HUMAN, Q8IXL6
    Function: Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in
    biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates
    its targets within the S-x-E/pS motif
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Enzyme Number (IUBMB): EC 2.7.11.11

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IDA--
    GO:0005509calcium ion binding IEA--
         
    FAM20C for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FAM20C:
     Decreased Wnt reporter activit 

         Selected MGI mutant phenotypes (inferred from 2 alleles(MGI details for Fam20c) (see all 16):
     behavior/neurological  cellular  craniofacial  digestive/alimentary  endocrine/exocrine gland 
     growth/size/body  hearing/vestibular/ear  hematopoietic system  homeostasis/metabolism  limbs/digits/tail 
     mortality/aging  nervous system  renal/urinary system  reproductive system  skeleton 

    FAM20C for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fam20ctm1Lex for FAM20C

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM20C
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM20C

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM20C
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM20C

    miRNA
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    miRTarBase miRNAs that target FAM20C:
    hsa-mir-92a-3p (MIRT049711)

    Block miRNA regulation of human, mouse, rat FAM20C using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM20C (see all 10):
    hsa-miR-137 hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-3692 hsa-miR-4325 hsa-miR-518a-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM20C

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: FAM20C (NM_020223)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM20C

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    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM20C 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20C


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    DMP4_HUMAN, Q8IXL6: Secreted (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum2
    extracellular2
    golgi apparatus2
    mitochondrion2
    cytosol1
    nucleus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IDA--
    GO:0005794Golgi apparatus IDA--
    GO:0070062extracellular vesicular exosome IDA19056867

    FAM20C for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM20C
    Interactions:

        Search GeneGlobe Interaction Network for FAM20C

    Selected Interacting proteins for FAM20C (Q8IXL62, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMN1Q166372, 3MINT-8271135 I2D: score=2 
    SMN2Q166372, 3MINT-8271135 I2D: score=2 
    FAM118BQ9BPY32, 3MINT-8255079 I2D: score=2 
    PFDN1O609252, 3MINT-8265842 I2D: score=2 
    SUV39H2Q9H5I12, 3MINT-8272465 I2D: score=2 
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    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001501skeletal system development IEA--
    GO:0006468protein phosphorylation IDA--
    GO:0030501positive regulation of bone mineralization IEA--
    GO:0036179osteoclast maturation IEA--
    GO:0040036regulation of fibroblast growth factor receptor signaling pathway IEA--

    FAM20C for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM20C (DMP4)

    1 HMDB Compound for FAM20C    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FAM20C gene: 
    NM_020223.3  

    Unigene Cluster for FAM20C:

    Family with sequence similarity 20, member C
    Hs.134742  [show with all ESTs]
    Unigene Representative Sequence: AK125281
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000313766(uc003sip.3) ENST00000477004 ENST00000471328 ENST00000515795(uc011jvn.2)
    ENST00000512382
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM20C using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM20C (see all 10):
    hsa-miR-137 hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-miR-32 hsa-miR-3692 hsa-miR-4325 hsa-miR-518a-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM20C
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    OriGene ORF clones in mouse, rat for FAM20C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM20C (NM_020223)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM20C
    Primer
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    OriGene qPCR primer pairs and template standards for FAM20C
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM20C
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM20C
      QuantiTect SYBR Green Assays in human, mouse, rat FAM20C
      QuantiFast Probe-based Assays in human, mouse, rat FAM20C

    Additional mRNA sequence: 

    AB545605.1 AF533706.1 AK054704.1 AK125281.1 AL390137.1 AL390147.1 BC009531.1 BC040074.1 
    BC068086.1 BC087853.1 

    12 DOTS entries:

    DT.430063  DT.91752628  DT.426172  DT.121645091  DT.121113546  DT.100059256  DT.92011743  DT.92068344 
    DT.121113541  DT.100828393  DT.95111829  DT.95344739 

    Selected AceView cDNA sequences (see all 60):

    CD723798 AI871150 BX474815 AI964007 CD368083 BU195990 BE779175 AW006130 
    CF995737 BM707039 BF512956 BM681201 AI916511 AI870124 BQ940628 BC068086 
    BQ674714 BG419616 BQ447694 BM836254 BF508683 BM747795 BE878897 AK125281 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FAM20C    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:              -                 -         
    SP2:                                -         
    SP3:              -     -     -     -         
    SP4:                                          


    ECgene alternative splicing isoforms for FAM20C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM20C expression in normal human tissues (normalized intensities)      FAM20C embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGCCCGTCGT
    FAM20C Expression
    About this image


    FAM20C expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Neurons
             Glycinergic Amacrine Cells Inner Nuclear Layer
     
     Blood (Hematopoietic System)
             Monocytes Peripheral Blood
     
     Eye (Sensory Organs)
             Glycinergic Amacrine Cells Inner Nuclear Layer
     
     Skeletal Muscle (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
    FAM20C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM20C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.134742

    UniProtKB/Swiss-Prot: DMP4_HUMAN, Q8IXL6
    Tissue specificity: Widely expressed

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM20C gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam20c1 , 5 family with sequence similarity 20, member C1, 5 83.71(n)1
    87.22(a)1
      5 (77.19 cM)5
    807521  NM_030565.61  NP_085042.21 
     1387545145 
    chicken
    (Gallus gallus)
    Aves FAM20C1 family with sequence similarity 20, member C 74.3(n)
    83.33(a)
      416445  XM_414753.4  XP_414753.4 
    lizard
    (Anolis carolinensis)
    Reptilia FAM20C6
    family with sequence similarity 20, member C
    71(a)
    1 ↔ 1
    GL343385.1(390402-430431)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004984481 extracellular serine/threonine protein kinase FAM2 more 69.53(n)
    75.99(a)
      100498448  XM_002931944.2  XP_002931990.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam20cb1 family with sequence similarity 20, member Cb 69.67(n)
    76.06(a)
      560397  XM_683800.6  XP_688892.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG311456
    --
    25(a)
    1 → many
    3R(19431473-19495378)
    worm
    (Caenorhabditis elegans)
    Secernentea H03A11.16
    Protein H03A11.1 (H03A11.1) mRNA, complete cds
    35(a)
    1 → many
    X(15209291-15213259) WBGene00010356


    ENSEMBL Gene Tree for FAM20C (if available)
    TreeFam Gene Tree for FAM20C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM20C gene
    FAM20A2  FAM20B2  
    3 SIMAP similar genes for FAM20C using alignment to 1 protein entry:     DMP4_HUMAN:
    FAM20A    FAM20B    Fam20A

    FAM20C for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM20C (see all 2050)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0375324
    Raine syndrome (RNS)4--see VAR_0375322 L R mis40--------
    VAR_0375334
    Raine syndrome (RNS)4--see VAR_0375332 R W mis40--------
    VAR_0375314
    Raine syndrome (RNS)4--see VAR_0375312 G R mis40--------
    VAR_0375304
    Raine syndrome (RNS)4--see VAR_0375302 G E mis40--------
    rs1128908801,2
    C,F--181212(+) GGGGGG/AGCCAG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1837767581,2
    --191017(+) CCACAA/CCCGGG 1 -- us2k10--------
    rs1894001091,2
    --191060(+) GTGACA/CCTGTC 1 -- us2k10--------
    rs1995389561,2
    C--191087(+) GTCCAC/TGTGAG 1 -- us2k10--------
    rs1415494401,2
    --191096(+) AGTGGA/GAGGAA 1 -- us2k10--------
    rs1507242271,2
    C--191132(+) GTGAAA/GCTGTC 1 -- us2k10--------
    rs49169341,2
    C--191280(+) TGGAAC/GAACTT 1 -- us2k1 tfbs30--------
    rs1476010571,2
    --191312(+) GGGTGA/CCCACG 1 -- us2k10--------
    rs730407611,2
    C--191314(+) GTGCCC/TACGGA 1 -- us2k13Minor allele frequency- T:0.10NA EA 242
    rs1403919561,2
    --191392(+) TTCACA/GTCAGA 1 -- us2k10--------
    rs609620571,2
    C,F--191423(+) GGCGGG/AGAGGG 1 -- us2k19Minor allele frequency- A:0.46WA NA CSA EA 368
    rs748388521,2
    C,F--191462(+) TAAGAG/TGGGGG 1 -- us2k12Minor allele frequency- T:0.08WA EA 238
    rs608608661,2
    C--191463(+) AAGAGG/CGGGGG 1 -- us2k11Minor allele frequency- C:0.50CSA 2
    rs1444215601,2
    --191492(+) CCCACC/TCGCCT 1 -- us2k10--------
    rs1478121681,2
    --191551(+) GCAGCC/TGGCTT 1 -- us2k10--------
    rs671385891,2
    C,F--191564(+) GGCACA/GGGGGA 1 -- us2k15Minor allele frequency- G:0.20WA NA EA 362
    rs582131471,2
    C,F--191644(+) CCTACT/AGGGAG 1 -- us2k19Minor allele frequency- A:0.46NA WA CSA EA 368
    rs1507861711,2
    C--191783(+) AGACG-/CACACAC 1 -- us2k10--------
    rs1501912271,2
    C--191791(+) CACAC-/AAACACA 1 -- us2k10--------
    rs1814934451,2
    --191810(+) ATACAA/CACGCA 1 -- us2k10--------
    rs117674931,2
    C,H--191859(+) cacgcC/Ttgcac 1 -- us2k12Minor allele frequency- T:0.00NA 4
    rs1414641721,2
    --191874(+) ACACCC/GCCGTC 1 -- us2k10--------
    rs69680871,2
    C,A--191904(+) CCCCCG/AGCACA 1 -- us2k13Minor allele frequency- A:0.12WA EA 240
    rs355903131,2
    C--192037(+) CTGGGT/CCCAGG 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs69492821,2
    C--192199(+) CCCCGA/CGCTCC 1 -- us2k10--------
    rs65833521,2
    C,F,A--192289(+) GCCCCC/ACACTC 1 -- us2k13Minor allele frequency- A:0.24NA EA 242
    rs45779081,2
    --192800(+) CTGCGA/GCCGCC 1 -- us2k10--------
    rs1169032501,2
    F--193091(+) CCGCCC/TGGCAC 1 -- ut511Minor allele frequency- T:0.08NA 120
    rs1850957881,2
    --193097(+) GGCACC/TGATGG 1 -- ut510--------
    rs732510521,2
    C--193222(+) GCGCCA/GGTTCC 2 Q R mis10--------
    rs1504011441,2
    C--193245(+) TGATGG/TTGTTC 2 V L mis10--------
    rs1903828291,2
    --193451(+) CCCAAA/CAAGCA 2 K N mis10--------
    rs132300321,2
    C,F,H--193461(+) ACACGC/TTCCGC 2 L F mis1 ese32Minor allele frequency- T:0.01NS 270
    rs2016316641,2
    --193799(+) AACCCA/GGACTG 2 P syn10--------
    rs1818536841,2
    --193916(+) GGCAGG/TGAGTG 1 -- int10--------
    rs1864490191,2
    --193979(+) ATAACC/TTCCTC 1 -- int10--------
    rs1383581361,2
    --194075(+) TCCTGA/TCCAGC 1 -- int10--------
    rs102667851,2
    C,F--194081(+) CCAGCC/TGTGGT 1 -- int19Minor allele frequency- T:0.34NA WA CSA EA 370
    rs285213931,2
    C,F--194153(+) CTGCCG/ACTGGG 1 -- int11Minor allele frequency- A:0.04WA 118
    rs1909105611,2
    --194167(+) TCAGAC/TACTTG 1 -- int10--------
    rs1807065141,2
    --194181(+) AGGGTC/GCTCTG 1 -- int10--------
    rs45825021,2
    C,F,A,H--194200(+) CCTTGC/GAGAAG 1 -- int115Minor allele frequency- N:0.00NS EA NA WA CSA 848
    rs42751771,2
    C,F,A,H--194247(+) GCTGGA/GGCAGA 1 -- int119Minor allele frequency- G:0.29NS EA NA CSA WA 2340
    rs570502451,2
    C,F--194368(+) GCCACG/AGCAGG 1 -- int12Minor allele frequency- A:0.09WA EA 238
    rs77792411,2
    C,F,A--194369(+) CCACGG/CCAGGA 1 -- int13Minor allele frequency- C:0.19WA 122
    rs784398011,2
    F--194432(+) CCTCCG/TCCACA 1 -- int11Minor allele frequency- T:0.04WA 118
    rs1428244631,2
    --194519(+) CCGAAA/GGTTAC 1 -- int10--------
    rs787243671,2
    C,F--194593(+) AATGTC/GCAGGC 1 -- int12Minor allele frequency- G:0.06WA EA 238
    rs1134801081,2
    C,F--194618(+) CTAAAC/TACACT 1 -- int14Minor allele frequency- T:0.06NA CSA WA 242
    rs1451097551,2
    --194720(+) CTCTCA/GGCAGG 1 -- int10--------
    rs1851369151,2
    C--194733(+) GAGACC/GGCCGC 1 -- int10--------
    rs1132455391,2
    C,F--194748(+) AGCAGC/TGAGTG 1 -- int13Minor allele frequency- T:0.20NA WA EA 240
    rs1176895401,2
    C,F--194756(+) GTGGCC/AAGGAA 1 -- int11Minor allele frequency- A:0.04NA 120
    rs2011886011,2
    --194775(+) AGCCC-/GCCCAC 1 -- int10--------
    rs616276311,2
    C--194776(+) AGCCCG/CCCACC 1 -- int11Minor allele frequency- C:0.00NA 2
    rs113575801,2
    C,F--194779(+) CCCCCA/-CCCCG 1 -- int12Minor allele frequency- -:0.50NA CSA 4
    rs798684511,2
    C--194798(+) TCCACC/TGCAGG 1 -- int14Minor allele frequency- T:0.14NA WA EA 360
    rs49169701,2
    C,F,A--194947(+) CAGGCT/CGCGTG 1 -- int110Minor allele frequency- C:0.46NA WA CSA EA 371
    rs1910641491,2
    --194950(+) GCTGCA/GTGGGC 1 -- int10--------
    rs1833807661,2
    --194967(+) TCCTCC/TATGGG 1 -- int10--------
    rs1389366941,2
    --195092(+) AGAGAA/GCTGGG 1 -- int10--------
    rs1145260171,2
    F--195102(+) GGAAGG/TTTCCT 1 -- int11Minor allele frequency- T:0.05WA 118
    rs1494347941,2
    --195120(+) TGGGCA/GTGTCT 1 -- int10--------
    rs1151931171,2
    F--195141(+) TGCAGC/GCTGTG 1 -- int11Minor allele frequency- G:0.05WA 118
    rs780624931,2
    C,F--195399(+) GCAGAC/TGTTGC 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1866862061,2
    --195425(+) CAGAGA/GCGCCT 1 -- int10--------
    rs1920367061,2
    C--195429(+) GGCGCC/TTTCAA 1 -- int10--------
    rs1448579491,2
    --195476(+) CTGGCA/GTCGGT 1 -- int10--------
    rs1481610401,2
    C--195480(+) CGTCGG/TTGCCC 1 -- int10--------
    rs102598461,2
    C--195500(+) CATCCC/GACTCA 1 -- int10--------
    rs102774571,2
    C,F,A,H--195501(+) ATCCGA/GCTCAC 1 -- int111Minor allele frequency- G:0.07NS NA WA 1386
    rs1876919451,2
    C--195579(+) GTGCAA/GAATTC 2 K E mis10--------
    rs617349701,2
    C,F--195594(+) CCCCCG/AGGGAG 2 /R /G mis12Minor allele frequency- A:0.01NS EU 657
    rs2009626221,2
    --195601(+) GGAGGC/TGGCCG 2 A V mis10--------
    rs2003819181,2
    C--195606(+) CGGCCG/ATGGAC 2 /M /V mis11Minor allele frequency- A:0.00EU 581
    rs2002253091,2
    --195657(+) GGTACA/GAGCTG 2 K E mis10--------
    rs1161818491,2
    C,F--195679(+) CAACCC/TGGCCA 2 P L mis11Minor allele frequency- T:0.02WA 118
    rs617302521,2
    C--195681(+) ACCCGG/ACCATC 2 /T /A mis12Minor allele frequency- A:0.01NS WA 196
    rs1925429921,2
    C--195751(+) GGTGCA/TCTCAG 1 -- int11Minor allele frequency- T:0.00EU 555
    rs2017200471,2
    --195760(+) AGGGCC/TGTCTG 1 -- int10--------
    rs1471297051,2
    --195842(+) ATTACA/GGCAGC 1 -- int10--------
    rs1821726521,2
    --195940(+) CTGCCA/GCACGA 1 -- int10--------
    rs1442792851,2
    --195951(+) TGAGCG/TGGGAG 1 -- int10--------
    rs1879864921,2
    --195970(+) ACAGCC/TGGTCC 1 -- int10--------
    rs1474094971,2
    --195980(+) CACTGC/TGCTCT 1 -- int10--------
    rs1391667011,2
    --196092(+) CCACCA/GGAAGC 1 -- int10--------
    rs803266301,2
    F--196126(+) TTCTAC/TACACG 1 -- int10--------
    rs102636101,2
    C,F,H--196186(+) AAGCCG/ATCCTT 1 -- int112Minor allele frequency- A:0.06NS EA NA WA CSA 638
    rs1926679551,2
    C--196210(+) CAAGGC/TGCTGT 1 -- int10--------
    rs1850567251,2
    --196271(+) CCTCCC/TAGATG 1 -- int10--------
    rs1405517511,2
    C--196276(+) CAGAT-/GGAGGAGT 1 -- int10--------
    rs1451449081,2
    --196466(+) AGGTAG/TTGAGG 1 -- int10--------
    rs624286461,2
    C,F--196595(+) TTTGCG/ACTGTG 1 -- int11Minor allele frequency- A:0.08NA 120
    rs1899785081,2
    --196716(+) TAGGTA/GTCCCC 1 -- int10--------
    rs49169711,2
    C,F,A,H--196780(+) CTCTGT/CCGGGT 1 -- int110Minor allele frequency- C:0.32NA WA CSA EA 372
    rs285599501,2
    C,F--196782(+) CTGCCG/AGGTGC 1 -- int12Minor allele frequency- A:0.02WA EA 238
    rs762494971,2
    C--196846(+) TCTCCC/TCACCC 1 -- int10--------
    rs1458203891,2
    C--196872(+) TCATA-/ACAGAGA 1 -- int10--------
    rs1442062891,2
    --196969(+) GAAAGC/TGCTGC 1 -- int10--------
    rs758768241,2
    C--196995(+) GCAGCG/AGTCTG 1 -- int13Minor allele frequency- A:0.05NA WA 240
    rs624286481,2
    F--197052(+) CAGAAC/TGTCCC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs793064691,2
    C,F--197074(+) AGAGTG/AAGCAT 1 -- int11Minor allele frequency- A:0.08NA 120
    rs1918953661,2
    --197076(+) AGTGAA/GCATGG 1 -- int10--------
    rs562490051,2
    C,F--197097(+) AATATC/TCGATG 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1450354761,2
    C--197206(+) CTCAAC/GGAGAT 1 -- int10--------
    rs736717611,2
    C,F--197233(+) CCTGAC/TAGCCC 1 -- int11Minor allele frequency- T:0.50WA 2
    rs1144249951,2
    C,F--197260(+) CGCACA/GGTGCC 1 -- int11Minor allele frequency- G:0.05WA 118
    rs49169351,2
    C,F,A,H--197267(+) TGCCCA/GATCCT 1 -- int132Minor allele frequency- G:0.44NA NS EA WA CSA 2879
    rs746746861,2
    C,F--197316(+) AGGCCG/ATGTGG 1 -- int12Minor allele frequency- A:0.06CSA EA 122
    rs69459921,2
    C--197322(+) TGTGGA/GGAGGA 1 -- int1 trp33Minor allele frequency- G:0.04WA NA 240
    rs1843746061,2
    --197391(+) TCCAGA/GTGGGT 1 -- int10--------
    rs624286491,2
    C--197428(+) GAGCCG/ATGCAC 1 -- int12Minor allele frequency- A:0.12NA 122
    rs1891977301,2
    --197464(+) AGCACA/GCAAGT 1 -- int10--------
    rs730407651,2
    C--197487(+) AGTGCC/TGCTGT 1 -- int10--------
    rs1504535641,2
    C--197488(+) GTGCCA/GCTGTC 1 -- int10--------
    rs69511121,2
    C,H--197535(+) TCCAGC/TGGGAT 1 -- int113Minor allele frequency- T:0.07NA WA CSA EA 376
    rs1819491611,2
    --197549(+) GCTGCA/GTGGGA 1 -- int10--------
    rs1383329591,2
    --197618(+) ACTTTA/GTGCGT 1 -- int10--------
    rs1858619571,2
    --197620(+) TTTGTA/GCGTGG 1 -- int10--------
    rs1895924081,2
    --197621(+) TTGTGC/TGTGGC 1 -- int10--------
    rs1812401471,2
    --197645(+) CCCCTC/TGTGTG 1 -- int10--------
    rs1471462301,2
    --197783(+) TGTGGC/GAGTTC 1 -- int10--------
    rs102804171,2
    C,F--197912(+) CCACCC/ACTCTT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs125405341,2
    C,F,H--197913(+) CACCCC/ATCTTT 1 -- int17Minor allele frequency- A:0.39NA WA EA 366
    rs49169721,2
    C,A,H--197933(+) GTCCCC/GGGGCA 1 -- int110Minor allele frequency- G:0.08NA WA CSA 253
    rs1867400741,2
    --197934(+) TCCCGA/GGGCAG 1 -- int10--------
    rs797943471,2
    F--198025(+) CCTCCG/ACCTGG 1 -- int11Minor allele frequency- A:0.01NA 120
    rs126729291,2
    C,F,H--198035(+) GGTGTG/ATCCTG 1 -- int19Minor allele frequency- A:0.05NS EA NA CSA WA 737
    rs624286501,2
    C,F--198067(+) AGGCCT/CGCCCC 1 -- int12Minor allele frequency- C:0.08WA NA 238
    rs1911825461,2
    --198091(+) CGCTCA/GCCTCC 1 -- int10--------
    rs344265301,2
    C--198149(+) GACCCG/CTCCAA 1 -- int12Minor allele frequency- C:0.19NA EA 122
    rs732510641,2
    C,F--198350(+) CTCACC/TGAGAA 1 -- int15Minor allele frequency- T:0.04WA NA EA 362
    rs1386216331,2
    C--198351(+) TCACCA/GAGAAC 1 -- int10--------
    rs40758621,2
    C,F,A,H--198401(+) TCTGAC/TTTACA 1 -- int120Minor allele frequency- T:0.29NS EA NA CSA WA 2346
    rs736717661,2
    C--198437(+) TCACTA/CGCGAA 1 -- int12Minor allele frequency- C:0.04WA 120
    rs77997861,2
    C,F,A,H--198440(+) CTAGCG/AAAAAC 1 -- int126Minor allele frequency- A:0.06NS EA NA WA 2900
    rs1828789211,2
    --198553(+) GGAACA/GGGAGT 1 -- int10--------
    rs42442211,2
    C,F,H--198640(+) tcatcG/Aaaata 1 -- int118Minor allele frequency- A:0.06NS EA NA WA 1888
    rs752680971,2
    --198645(+) GAAATA/TCCTGC 1 -- int10--------
    rs1861470021,2
    C--198647(+) AATACC/TTGCAG 1 -- int10--------
    rs1909540161,2
    --198657(+) GTTCCC/GAAATA 1 -- int10--------
    rs1473865031,2
    --198703(+) GCAAAC/TACGAG 1 -- int10--------
    rs800602141,2
    C,F--198779(+) TGGGGG/CAAGCT 1 -- int12Minor allele frequency- C:0.02WA EA 238
    rs1484291331,2
    --198816(+) GCAGCA/GGCATT 1 -- int10--------
    rs1835264171,2
    --198869(+) GGCAGC/GTGCCT 1 -- int10--------
    rs1875753621,2
    --198872(+) AGGTGC/TCTGAG 1 -- int10--------
    rs1426362441,2
    --198897(+) CAGTCC/TAGATG 1 -- int10--------
    rs40741191,2
    C,F,A,H--198903(-) GCCCAA/GCATCT 1 -- int129Minor allele frequency- N:0.00NS EA NA WA CSA 2555
    rs1505508791,2
    --198943(+) GATGCC/TCACAG 1 -- int10--------
    rs1396225321,2
    --199027(+) ATGGGA/CGCTGC 1 -- int10--------
    rs1928134941,2
    --199075(+) CGGCAC/TAAGAG 1 -- int10--------
    rs40741181,2
    C,F,A,H--199163(-) TCAGGT/CCAGCC 1 -- int127Minor allele frequency- C:0.28NS EA NA WA CSA 2535
    rs1825885881,2
    --199209(+) CGAACC/TTCCAG 1 -- int10--------
    rs586985421,2
    --199306(+) AGAGCC/TTGGTG 1 -- int10--------
    rs1881004361,2
    C--199386(+) CTCCAC/TAGCGA 1 -- int10--------
    rs1152362241,2
    F--199420(+) GGAGGC/GTTGTC 1 -- int11Minor allele frequency- G:0.01WA 118
    rs1166797371,2
    F--199463(+) GTTCTG/CTCCCC 1 -- int11Minor allele frequency- C:0.02WA 118
    rs1145193991,2
    F--199475(+) CAGCTG/ATCCGG 1 -- int11Minor allele frequency- A:0.01WA 118
    rs69591251,2
    C,F,H--199503(+) TAATCT/CCAAGT 1 -- int115Minor allele frequency- C:0.06NS EA NA WA 1870
    rs1917521791,2
    --199596(+) GGAACA/GGTTCC 1 -- int10--------
    rs1153849041,2
    F--199651(+) CGCCAC/TGTGGT 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1842425531,2
    --199746(+) AAGAGC/TCTTGG 1 -- int10--------
    rs1890420891,2
    C--199785(+) ATCGGG/TCATGC 1 -- int10--------
    rs748686201,2
    C--199797(+) GTGCCT/CTGGGC 1 -- int13Minor allele frequency- C:0.11NA EA 242
    rs1924320761,2
    --199885(+) GGATTC/TGGGCA 1 -- int10--------
    rs1180332791,2
    C,F--200009(+) TGACAC/TTGATT 1 -- int11Minor allele frequency- T:0.04EA 120
    rs286651911,2
    C--200011(+) ACACTA/GATTGA 1 -- int112Minor allele frequency- G:0.00NA WA CSA EA 373
    rs732510701,2
    C--200081(+) TCAAGG/AAACAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs1170281651,2
    C,F--200095(+) GCTTCC/TGCTGG 1 -- int11Minor allele frequency- T:0.03EA 120
    rs560151421,2
    C,F--200260(+) GTCACG/AGTCCC 1 -- int12Minor allele frequency- A:0.09WA 120
    rs1465509391,2
    --200277(+) TCGCTC/TGGCCG 1 -- int10--------
    rs1132417711,2
    C,F--200281(+) TCGGCC/AGGCCT 1 -- int12Minor allele frequency- A:0.34NA EA 122
    rs1858467401,2
    --200294(+) AGAGAG/TAAAAG 1 -- int10--------
    rs1891493541,2
    --200331(+) CATGGC/TCCCAG 1 -- int10--------
    rs792407191,2
    F--200398(+) ATTTCA/TAGTGG 1 -- int11Minor allele frequency- T:0.07WA 118
    rs1412517361,2
    C--200407(+) GGAGCC/TTGGAG 1 -- int10--------
    rs1998970831,2
    C--200485(+) AGCTC-/ATATGCT 1 -- int10--------
    rs1162670351,2
    C,F--200532(+) GTGCTG/AAGCAG 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1170006931,2
    C,F--200545(+) ACAGCA/TGCCCC 1 -- int11Minor allele frequency- T:0.07NA 120
    rs102704451,2
    C,F,A,H--200550(+) AGCCCC/TCTAGC 1 -- int18Minor allele frequency- T:0.02NS EA NA 1164
    rs1457855621,2
    C--200572(+) GCCCCA/GATGCG 1 -- int10--------
    rs749170111,2
    C,F--200597(+) CCTTCT/CGATGC 1 -- int11Minor allele frequency- C:0.09EA 120
    rs1179414441,2
    C,F--200659(+) CTTTCA/GAAATA 1 -- int11Minor allele frequency- G:0.03EA 120
    rs127181231,2
    C,F,A,H--200682(+) AAGAAA/GATCGT 1 -- int122Minor allele frequency- G:0.20NS EA NA WA 2760
    rs127181241,2
    C,F,A,H--200735(+) TGTCCA/TGAGGG 1 -- int116Minor allele frequency- T:0.38NS EA NA WA CSA 1025
    rs730401581,2
    C--200775(+) TGCTGA/TTGGGG 1 -- int10--------
    rs1806724101,2
    --200785(+) GCCTTA/GCCTGT 1 -- int10--------
    rs755793491,2
    C,F--200885(+) GTAGGT/GTCCCA 1 -- int15Minor allele frequency- G:0.17NA CSA WA EA 362
    rs793517601,2
    C,F--200911(+) TGATGC/ACAGCC 1 -- int11Minor allele frequency- A:0.02NA 120
    rs755892851,2
    C--200916(+) CCAGCC/TCCAGG 1 -- int12Minor allele frequency- T:0.04CSA EA 122
    rs797843351,2
    C,F--200957(+) CCTCAA/GAACCA 1 -- int11Minor allele frequency- G:0.13WA 118
    rs1859871001,2
    --200971(+) CCCTCA/GGTGCC 1 -- int10--------
    rs125372921,2
    C,F,H--201060(+) GTGTGG/CGGTGG 1 -- int111Minor allele frequency- C:0.23NA WA CSA EA 373
    rs1885336041,2
    --201093(+) CTCCCA/GGTGTC 1 -- int10--------
    rs1437657661,2
    --201166(+) CATTCA/GTCTTC 1 -- int10--------
    rs1813740601,2
    --201232(+) TGACCA/GTGACC 1 -- int10--------
    rs1860408391,2
    --201379(+) GGTTAA/CTTTAA 1 -- int10--------
    rs1481330171,2
    --201426(+) TCCCAC/TGAGAA 1 -- int10--------
    rs1112698621,2
    F--201464(+) GTCTCC/TATCCC 1 -- int12Minor allele frequency- T:0.03CSA WA 120
    rs1908104771,2
    --201562(+) CTGCTC/GTGGGT 1 -- int10--------
    rs1821215491,2
    --201667(+) CATTAA/GTATTT 1 -- int10--------
    rs104809241,2
    C,F--201782(+) GTCTCG/ATGCTG 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1141700971,2
    F--201846(+) GCCCCG/AAACTC 1 -- int11Minor allele frequency- A:0.02WA 118
    rs1426528401,2
    C--201853(+) ACTCTC/TAGTGC 1 -- int10--------
    rs1872038761,2
    --201871(+) AACATA/GAAATA 1 -- int10--------
    rs624286521,2
    C,F--201901(+) TGTTCG/ATGCAT 1 -- int12Minor allele frequency- A:0.09NA 122
    rs1919959171,2
    --201926(+) CTAGTA/GCACGT 1 -- int10--------
    rs1469141331,2
    --201929(+) GTGCAC/TGTTAA 1 -- int10--------
    rs1393288131,2
    --201964(+) AGTGAC/TGTAGA 1 -- int10--------
    rs1826794551,2
    --201987(+) AATCAA/GTAGGA 1 -- int10--------
    rs126721461,2
    C,F,H--202012(+) CTGACG/AGATAT 1 -- int16Minor allele frequency- A:0.08NS NA WA EA 570
    rs1876715891,2
    --202043(+) GCGAGG/TCCGGG 1 -- int10--------
    rs1427248961,2
    --202056(+) AGAAGC/TAGACT 1 -- int10--------
    rs1113751381,2
    C,F--202225(+) ACTGGG/AGAATG 1 -- int11Minor allele frequency- A:0.50NA 2
    rs119807271,2
    C,F,H--202268(+) AGGACG/AGGTGG 1 -- int16Minor allele frequency- A:0.42NA WA 12
    rs126661121,2
    C,F,H--202419(+) GGGTGG/ACTGCT 1 -- int17Minor allele frequency- A:0.30NS EA NA WA 650
    rs1900179161,2
    --202453(+) GGGGGA/GCGCTA 1 -- int10--------
    rs119807911,2
    C,F,H--202472(+) TTCCCG/ATGTGC 1 -- int18Minor allele frequency- A:0.22EA NS NA WA CSA 380
    rs1826484081,2
    --202480(+) TGCATA/GGAGAG 1 -- int10--------
    rs1873375401,2
    --202559(+) GAGGAC/TGGGTA 1 -- int10--------
    rs1922847751,2
    --202705(+) GAGGAC/TGGGTG 1 -- int10--------
    rs1417309531,2
    --202706(+) AGGACC/GGGTGG 1 -- int10--------
    rs1121535981,2
    C--202763(+) CTTCCA/CGTGTG 1 -- int10--------
    rs1119203871,2
    C--202820(+) GGGCCC/TGTGGA 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1851731951,2
    --202888(+) TGTTTC/TCAGAA 1 -- int10--------
    rs1888827631,2
    --203130(+) GCCCCC/TGCCTC 1 -- int10--------
    rs1931129021,2
    --203150(+) CATGGA/GCATCA 1 -- int10--------
    rs1843301171,2
    --203203(+) GGCAGC/GCTCTG 1 -- int10--------
    rs1884273161,2
    --203221(+) CCTGTC/GCACTG 1 -- int10--------
    rs1125208231,2
    F--203262(+) TCTCCA/C/GTCAGT 1 -- int11CSA 1
    rs1147488881,2
    --203284(+) GACCTA/GTGCCC 1 -- int10--------
    rs1394084921,2
    --203293(+) CCACAC/TGCCTG 1 -- int10--------
    rs344924421,2
    C,F,H--203326(+) AGCTTT/CCCAAG 1 -- int120Minor allele frequency- C:0.23NS EA NA WA 2346
    rs1130351491,2
    F--203333(+) CAAGCG/ATCGTG 1 -- int11Minor allele frequency- A:0.00CSA 1
    rs1126921271,2
    F--203344(+) AACTTC/TGGTCT 1 -- int11Minor allele frequency- T:0.00CSA 1
    rs1436333871,2
    --203454(+) GACCCA/GATCAG 1 -- int10--------
    rs285706121,2
    C--203470(+) GGAGGG/TTGGGC 1 -- int13Minor allele frequency- T:0.12NA WA EA 240
    rs744148731,2
    C,F--203472(+) AGGGTG/TGGCGT 1 -- int12Minor allele frequency- T:0.06WA EA 238
    rs1816352901,2
    --203476(+) TGGGCG/TTCTGT 1 -- int10--------
    rs1512357871,2
    --203516(+) GGCCTA/GAGACG 1 -- int10--------
    rs1112862501,2
    F--203550(+) TTGCAG/AGGAGA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1921786421,2
    --203750(+) GGAAGA/GTAGGA 1 -- int10--------
    rs1822315001,2
    --203805(+) ATATGC/TTGTTA 1 -- int10--------
    rs1850161821,2
    --203885(+) GTTAAA/GTCCTG 1 -- int10--------
    rs286746541,2
    C,F--203917(+) ATGGGA/GGCATC 1 -- int112Minor allele frequency- G:0.42NA WA CSA EA 373
    rs1393173681,2
    --203938(+) TAATCC/TGGCTA 1 -- int10--------
    rs1898738651,2
    --203955(+) TTCTCA/TTCGTC 1 -- int10--------
    rs1825143481,2
    --203972(+) TTATTA/GTCTTA 1 -- int10--------
    rs1120566301,2
    F--204156(+) ATGGCA/GTCTAA 1 -- int11Minor allele frequency- G:0.00CSA 1
    rs1443662961,2
    C--204163(+) CTAAG-/TTTTTA 1 -- int10--------
    rs1115278181,2
    F--204201(+) CATACG/ACTGTT 1 -- int12Minor allele frequency- A:0.03CSA WA 119
    rs1390859081,2
    C--204221(+) GAAAA-/CCCCCC 1 -- int10--------
    rs1122573511,2
    F--204235(+) TACCCA/GGTGAG 1 -- int11Minor allele frequency- G:0.00CSA 1
    rs1452385251,2
    --204246(+) AAGCCA/GGGATG 1 -- int10--------
    rs557767621,2
    C,F--204257(+) GAGCCC/TGTTTA 1 -- int15Minor allele frequency- T:0.07WA NA EA 362
    rs1901291991,2
    --204337(+) AGATTC/TGTTGC 1 -- int10--------
    rs1425639281,2
    C--204368(+) GGCACA/GGCCTC 1 -- int10--------
    rs1467526391,2
    --204402(+) ACTGCA/GCAGTG 1 -- int10--------
    rs284703141,2
    C,F--204431(+) AGCCCC/GAGTCT 1 -- int11Minor allele frequency- G:0.02WA 118
    rs1835113761,2
    --204455(+) TCAAAC/TGTGGT 1 -- int10--------
    rs1175747501,2
    C,F--204488(+) GCAGAC/TGCTGC 1 -- int11Minor allele frequency- T:0.04EA 120
    rs283619261,2
    C--204517(+) TGACCC/TGGGGT 1 -- int14Minor allele frequency- T:0.17NA WA EA 360
    rs1479670241,2
    --204573(+) GGGCAC/TGTGGC 1 -- int10--------
    rs736717671,2
    C--204574(+) GGCACG/ATGGCG 1 -- int13Minor allele frequency- A:0.03WA EA 240
    rs1145446951,2
    F--204578(+) CGTGGC/TGCTTG 1 -- int11Minor allele frequency- T:0.02WA 118
    rs285022631,2
    C,F--204608(+) AGCCCC/TCACAC 1 -- int13Minor allele frequency- T:0.17WA NA EA 358
    rs287218861,2
    C,F--204609(+) GCCCCC/TACACT 1 -- int13Minor allele frequency- T:0.17WA NA EA 358
    rs1418179711,2
    C--204746(+) GGTGAG/TTCCCC 1 -- int10--------
    rs603435551,2
    C,F--204910(+) GTTCTC/TGGTGC 1 -- int13Minor allele frequency- T:0.05WA EA 240
    rs1434488511,2
    --204918(+) TGCTCA/GGGGAG 1 -- int10--------
    rs1479742241,2
    --204929(+) GGGACA/GTGGCA 1 -- int10--------
    rs1884529761,2
    --204951(+) CTTGCC/TGTGGT 1 -- int10--------
    rs1416917291,2
    --204952(+) TTGCCA/GTGGTG 1 -- int10--------
    rs1501235841,2
    --205034(+) GAGGCA/GTGTCA 1 -- int10--------
    rs1384317201,2
    --205061(+) GCAGCC/TGAGTT 1 -- int10--------
    rs1417967871,2
    --205130(+) CAGGCC/GTCCAC 1 -- int10--------
    rs732510721,2
    C,F--205136(+) TCCACG/ATCCTG 1 -- int15Minor allele frequency- A:0.08NA WA EA 362
    rs1135573621,2
    C,F--205156(+) GTTTTG/CTAGAA 1 -- int11Minor allele frequency- C:0.00CSA 1
    rs286896891,2
    C,F--205244(+) ACCACA/GGACAC 1 -- int15Minor allele frequency- G:0.41NA CSA EA 246
    rs283977111,2
    C,F--205255(+) GCACCG/ACCACG 1 -- int13Minor allele frequency- A:0.50NA CSA 6
    rs1857225521,2
    --205256(+) CACCAC/TCACGA 1 -- int10--------
    rs286298831,2
    C--205270(+) CAGCCT/CCCCGA 1 -- int12Minor allele frequency- C:0.00NA 4
    rs596970381,2
    C--205281(+) GTAGCC/TGGGAC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs361932721,2
    C--205301(+) GCACCG/ACCACG 1 -- int12Minor allele frequency- A:0.25NA CSA 4
    rs1136159061,2
    C,F--205316(+) CAGCCC/TCCCGA 1 -- int11Minor allele frequency- T:0.50NA 2
    rs1135397861,2
    C--205327(+) GTAGCC/TGGGAC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs284069631,2
    --205370(+) GAGTAG/TCTGGG 1 -- int10--------
    rs286813901,2
    C--205372(+) GTAGCC/TGGGAC 1 -- int11Minor allele frequency- T:0.50NA 2
    rs732510741,2
    C,F--205474(+) GCCTCG/CAGCAA 1 -- int15Minor allele frequency- C:0.06NA WA EA 362
    rs286265011,2
    C,F--205607(+) GAGGCC/TGAGCA 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1867940661,2
    --205627(+) GAGGTC/TGCGTC 1 -- int10--------
    rs1912503471,2
    --205642(+) CCCGTC/TGACGG 1 -- int10--------
    rs1838317931,2
    --205646(+) TCGACA/GGTTTC 1 -- int10--------
    rs1448296811,2
    C--205723(+) GCCCAA/GGTGAA 1 -- int10--------
    rs1885420181,2
    --205760(+) TTCTCA/GTCTGC 1 -- int10--------
    rs1813551341,2
    --205762(+) CTCGTC/TTGCGC 1 -- int10--------
    rs1852003091,2
    --205766(+) TCTGCA/GCCCTC 1 -- int10--------
    rs1479183211,2
    --205850(+) AAGCCC/TGCTGT 1 -- int10--------
    rs1418839561,2
    --205875(+) TCCCTC/TCCAGC 1 -- int10--------
    rs796766931,2
    F--205945(+) CCTGAG/ACTTTC 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1901206981,2
    --205969(+) ACAAAC/TCCATC 1 -- int10--------
    rs1823520911,2
    --205993(+) CCCATC/TCCGCC 1 -- int10--------
    rs1864441721,2
    --206007(+) TCCTGC/TAGGGC 1 -- int10--------
    rs285367001,2
    --206026(+) CCCCGA/GGCTCC 1 -- int10--------
    rs1453998161,2
    --206046(+) GCACAC/TGCGCG 1 -- int10--------
    rs1490407711,2
    --206093(+) GGAGCA/GTCTCC 1 -- int10--------
    rs1430261411,2
    --206196(+) ACCTCG/TCAGAT 1 -- int10--------
    rs732510751,2
    C,F--206270(+) AGCTGC/ACGCAG 1 -- int14Minor allele frequency- A:0.08NA WA 242
    rs751312901,2
    C,F--206363(+) TGCCCT/CGCTGC 1 -- int11Minor allele frequency- C:0.12WA 118
    rs1113690711,2
    F--206380(+) CTGGCC/TGCCCT 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs730401651,2
    C,F--206381(+) TGGCCG/ACCCTT 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1138830791,2
    C--206453(+) CTCCCA/GTGCAC 1 -- int10--------
    rs1126886841,2
    C--206481(+) GGTCCC/GCTCGG 1 -- int12Minor allele frequency- G:0.27NA EA 122
    rs725038721,2
    C--206512(+) TGACGC/TGTCTG 1 -- int11Minor allele frequency- T:0.50NA 2
    rs715164971,2
    C,F--206513(+) GACGCA/GTCTGT 1 -- int14Minor allele frequency- G:0.29NA CSA 7
    rs1115016111,2
    C--206536(+) GGCCCC/TGCACA 1 -- int11Minor allele frequency- T:0.50NA 2
    rs624302811,2
    C--206577(+) CCCTCG/AGCCCC 1 -- int13Minor allele frequency- A:0.17WA NA 6
    rs777288171,2
    C--206611(+) TGACGC/TGTCTG 1 -- int11Minor allele frequency- T:0.50NA 2
    rs361989131,2
    C,F--206635(+) GGCCCC/TGCACA 1 -- int12Minor allele frequency- T:0.50NA 4
    rs741954471,2
    C--206644(+) CACGTG/ATCCAC 1 -- int11Minor allele frequency- A:0.50NA 2
    rs1138687631,2
    C--206658(+) GACGCG/ATCGGT 1 -- int11Minor allele frequency- A:0.50NA 2
    rs624302821,2
    C,F--206710(+) TGACGC/TGTCTG 1 -- int12Minor allele frequency- T:0.50NA 4
    rs1139186761,2
    C--206711(+) GACGCA/GTCTGT 1 -- int11Minor allele frequency- G:0.00CSA 1
    rs1122554041,2
    C,F--206734(+) GGCCCC/TGCACA 1 -- int13Minor allele frequency- T:0.50NA WA 6
    rs1134470561,2
    C,F--206740(+) GCACAC/AGTGCT 1 -- int12Minor allele frequency- A:0.50NA WA 4
    rs675938311,2
    C,F--206763(+) TGACGC/TGTCTG 1 -- int13Minor allele frequency- T:0.50NA 6
    rs715362731,2
    C,F--206772(+) TGTCAC/TGGTCC 1 -- int12Minor allele frequency- T:0.50NA 4
    rs1120895671,2
    C--206787(+) GGCCCC/TGCACA 1 -- int11Minor allele frequency- T:0.50NA 2
    rs3683838311,2
    C--206794(+) ACACG-/TG    
       CTCAC
    TGTCC
    1 -- int10--------
    rs715362741,2
    C--206833(+)