Aliases for FAM20C Gene
External Ids for FAM20C Gene
Previous GeneCards Identifiers for FAM20C Gene
This gene encodes a member of the family of secreted protein kinases. The encoded protein binds calcium and phosphorylates proteins involved in bone mineralization. Mutations in this gene are associated with the autosomal recessive disorder Raine syndrome. [provided by RefSeq, Apr 2014]
GeneCards Summary for FAM20C Gene
FAM20C (Family With Sequence Similarity 20, Member C) is a Protein Coding gene. Diseases associated with FAM20C include raine syndrome. GO annotations related to this gene include calcium ion binding and protein serine/threonine kinase activity. An important paralog of this gene is FAM20B.
UniProtKB/Swiss-Prot for FAM20C Gene
Calcium-binding kinase that phosphorylates the caseins and several secreted proteins implicated in biomineralization, including the secretory calcium binding phosphoproteins (SCPP). Preferencially phosphorylates its targets within the S-x-E/pS motif.