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FAM20A Gene

protein-coding   GIFtS: 50
GCID: GC17M066533

Family With Sequence Similarity 20, Member A

  See FAM20A-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 20, Member A1 2
AIGFS2 5
FP27472
Protein FAM20A2

External Ids:    HGNC: 230151   Entrez Gene: 547572   Ensembl: ENSG000001089507   OMIM: 6110625   UniProtKB: Q96MK33   

Export aliases for FAM20A gene to outside databases

Previous GC identifers: GC17M066995 GC17M067130 GC17M064044 GC17M061916


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FAM20A Gene:
This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus
has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced
transcript variants have been identified. (provided by RefSeq, Aug 2011)

GeneCards Summary for FAM20A Gene:
FAM20A (family with sequence similarity 20, member A) is a protein-coding gene. Diseases associated with FAM20A include amelogenesis imperfecta and gingival hyperplasia syndrome, and amelogenesis imperfecta and gingival fibromatosis syndrome. An important paralog of this gene is FAM20B.

Gene Wiki entry for FAM20A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM20A gene promoter:
         NF-1   AML1a   POU3F2 (N-Oct-5a)   IRF-1   POU3F2   Arnt   AREB6   MEF-2A   Msx-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM20A promoter sequence
   Search Chromatin IP Primers for FAM20A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM20A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24.2   Ensembl cytogenetic band:  17q24.2   HGNC cytogenetic band: 17q24.2

FAM20A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM20A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M066533:  view genomic region     (about GC identifiers)

Start:
66,531,254 bp from pter      End:
66,597,530 bp from pter
Size:
66,277 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3 (See protein sequence)
Recommended Name: Protein FAM20A precursor  
Size: 541 amino acids; 61417 Da
Secondary accessions: B2RN47 B2RN49 Q9UF95

Explore the universe of human proteins at neXtProt for FAM20A: NX_Q96MK3

Explore proteomics data for FAM20A at MOPED

Post-translational modifications: 

  • N-glycosylated (By similarity)1
  • Glycosylation2 at Asn70, Asn145, Asn287, Asn388, Asn538

  • See FAM20A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001230675.1  NP_060035.2  

    ENSEMBL proteins: 
     ENSP00000468308   ENSP00000467884   ENSP00000464910  

    FAM20A Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for FAM20A

     
    Search eBioscience for Proteins for FAM20A 

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    LSBio Antibodies in human, mouse, rat for FAM20A

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    Cloud-Clone Corp. CLIAs for FAM20A
    Search eBioscience for ELISAs for FAM20A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR009581 DUF1193
     IPR024869 FAM20

    Graphical View of Domain Structure for InterPro Entry Q96MK3

    ProtoNet protein and cluster: Q96MK3

    1 Blocks protein domain: IPB009581 Protein of unknown function DUF1193

    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
    Similarity: Belongs to the FAM20 family


    Find genes that share domains with FAM20A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for FAM20A:
     Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Fam20a):
     cardiovascular system  craniofacial  growth/size/body  mortality/aging  renal/urinary system 
     respiratory system 

    Find genes that share phenotypes with FAM20A           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Fam20atm1Lex for FAM20A

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM20A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM20A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM20A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM20A

    miRNA
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    Block miRNA regulation of human, mouse, rat FAM20A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate FAM20A:
    hsa-miR-520f hsa-miR-924 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidFAM20A 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for FAM20A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM20A

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FA20A_HUMAN, Q96MK3: Secreted (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    endoplasmic reticulum1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0070062extracellular vesicular exosome IDA19199708

    Find genes that share ontologies with FAM20A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM20A
    Interactions:

        Search GeneGlobe Interaction Network for FAM20A

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070166enamel mineralization IEA--

    Find genes that share ontologies with FAM20A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM20A (FA20A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM20A gene (2 alternative transcripts): 
    NM_001243746.1  NM_017565.3  

    Unigene Cluster for FAM20A:

    Family with sequence similarity 20, member A
    Hs.268874  [show with all ESTs]
    Unigene Representative Sequence: NM_001243746
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000226094(uc002jhn.3 uc010wqp.2 uc002jho.3) ENST00000592554
    ENST00000590873 ENST00000375556 ENST00000590074 ENST00000592847
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM20A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate FAM20A:
    hsa-miR-520f hsa-miR-924 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidFAM20A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM20A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM20A
    Clone
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    OriGene clones in human, mouse for FAM20A (see all 7)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM20A (NM_017565)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM20A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM20A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM20A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM20A
      QuantiFast Probe-based Assays in human, mouse, rat FAM20A

    Additional mRNA sequence: 

    AB545606.1 AK056789.1 AK298071.1 AL133105.1 AY358197.1 BC036222.1 BC136686.1 BC136689.1 
    NR_027751.1 

    11 DOTS entries:

    DT.97781965  DT.100742066  DT.91686027  DT.97776150  DT.100737227  DT.455153  DT.121011506  DT.121011469 
    DT.121011442  DT.91848322  DT.95315373 

    Selected AceView cDNA sequences (see all 102):

    AI823909 BU741994 AI738519 AI123563 BX110034 AL133105 AI244363 AV650290 
    BX503337 CD358576 CA944755 BE857141 BU626202 AI763057 CB530015 AI857676 
    AF447872 AI128237 AI202236 CR597331 BM921367 BG054677 BI462611 BI463594 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM20A    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b
    SP1:        -                                         -                                 
    SP2:                                                                                    


    ECgene alternative splicing isoforms for FAM20A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM20A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FAM20A Expression
    About this image


    FAM20A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Epiphyseal End
     
     Neural Crest (Gastrulation Derivatives)
             PureStem MEL2, NCr-fac Progenitor
    FAM20A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM20A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.268874

    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
    Tissue specificity: Highly expressed in lung and liver. Intermediate levels in thymus and ovary

        Custom PCR Arrays for FAM20A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM20A gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam20a1 , 5 family with sequence similarity 20, member A1, 5 85.39(n)1
    85.52(a)1
      11 (72.37 cM)5
    2086591  NM_153782.11  NP_722477.11 
     1096697495 
    chicken
    (Gallus gallus)
    Aves FAM20A1 family with sequence similarity 20, member A 77.12(n)
    79.17(a)
      417439  XM_415690.4  XP_415690.4 
    lizard
    (Anolis carolinensis)
    Reptilia FAM20A6
    family with sequence similarity 20, member A
    74(a)
    1 ↔ 1
    GL343260.1(1724494-1820183)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fam20a1 family with sequence similarity 20, member A 62.51(n)
    61.96(a)
      100145530  NM_001126969.1  NP_001120441.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.222082 Transcribed sequence with weak similarity to protein more 74.91(n)    CK399583.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG311456
    --
    19(a)
    1 → many
    3R(19431473-19495378)
    worm
    (Caenorhabditis elegans)
    Secernentea H03A11.16
    Protein H03A11.1 (H03A11.1) mRNA, complete cds
    31(a)
    1 → many
    X(15209291-15213259) WBGene00010356


    ENSEMBL Gene Tree for FAM20A (if available)
    TreeFam Gene Tree for FAM20A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM20A gene
    FAM20B2  FAM20C2  
    4 SIMAP similar genes for FAM20A using alignment to 4 protein entries:     FA20A_HUMAN (see all proteins):
    FP2747    Fam20A    FAM20C    FAM20B

    Find genes that share paralogs with FAM20A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM20A (see all 1513)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1402717761,2
    C--61926587(+) TACAG-/CACAAC 3 -- int10--------
    rs1488895441,2
    C--61929898(+) CAATA-/TTGTTGTG 3 -- int10--------
    rs2022147871,2
    C--61935909(+) CACAC-/ATATGCA 3 -- int10--------
    rs355761571,2
    C--61950673(+) TTATC-/TCTTCA 2 -- int10--------
    rs713558911,2
    C--61953883(+) TATAT-/A/AT  
     ATATATA
    TATAT
    4 -- int1 cds11NA 2
    rs1893687921,2
    --61953894(+) ATATAC/TATATA 2 -- int10--------
    rs608402241,2
    C--61961832(+) ATAGT-/ATTGCA 2 -- int10--------
    rs1452620851,2
    C--61961834(+) AGTTT-/AA/TAA
            
    GCATT
    4 -- int1 cds10--------
    rs567195341,2
    C--61961836(+) GTTTG-/AA/A  
      AA
    /TAA
    CATTT
    6 -- int1 cds10--------
    rs801759221,2
    --61972745(+) CCTGGA/C/GCCAAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for FAM20A (66531254 - 66597530 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for FAM20A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2716148CNV Deletion23290073
    esv2661984CNV Deletion23128226
    esv2677068CNV Deletion23128226
    nsv507856CNV Insertion20534489
    nsv522126CNV Loss19592680
    nsv510723CNV Loss20534489
    nsv833524CNV Gain17160897

    Human Gene Mutation Database (HGMD): FAM20A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM20A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM20A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611062   
    OMIM disorders: 614253  
    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
  • Amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS) [MIM:614253]: An autosomal recessive
    condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis
    imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal
    radiolucencies, and unerupted teeth. Note=The disease is caused by mutations affecting the gene represented in
    this entry

  • 4 diseases for FAM20A:    
    About MalaCards
    amelogenesis imperfecta and gingival hyperplasia syndrome    amelogenesis imperfecta and gingival fibromatosis syndrome    amelogenesis imperfecta, type ig    hypercementosis

    2 diseases from the University of Copenhagen DISEASES database for FAM20A:
    Hypercementosis     Amelogenesis imperfecta

    Find genes that share disorders with FAM20A           About GenesLikeMe

    Genetic Association Database (GAD): FAM20A

    Export disorders for FAM20A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM20A gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with FAM20A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells. (PubMed id 15676076)1, 2, 9 Nalbant D.... Williams S.C. (BMC Genomics 2005)
    2. Novel FAM20A mutations in hypoplastic amelogenesis imperfecta. (PubMed id 21990045)1, 2 Cho S.H....Kim J.W. (Hum. Mutat. 2012)
    3. Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. (PubMed id 21549343)1, 2 O'Sullivan J.... Dixon M.J. (Am. J. Hum. Genet. 2011)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. FAM20A mutations associated with enamel renal syndrome. (PubMed id 24196488)1 Wang S.K....Hu J.C. (J. Dent. Res. 2014)
    7. FAM20A mutations can cause enamel-renal syndrome (ERS). (PubMed id 23468644)1 Wang S.K....Hu J.C. (PLoS Genet. 2013)
    8. Altered gene expression pattern in peripheral blood mononuclear cells in patients with acute myocardial infarction. (PubMed id 23185530)1 Kiliszek M....Opolski G. (PLoS ONE 2012)
    9. Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations. (PubMed id 23434854)1 Jaureguiberry G....Kleta R. (Nephron Physiol 2012)
    10. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). (PubMed id 19199708)1 Gonzalez-Begne M....Yates J.R. (J. Proteome Res. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54757 HGNC: 23015 AceView: FAM20A Ensembl:ENSG00000108950 euGenes: HUgn54757
    ECgene: FAM20A H-InvDB: FAM20A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM20A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM20A gene:
    Search GeneIP for patents involving FAM20A

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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