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Aliases for FAM209B Gene

Aliases for FAM209B Gene

  • Family With Sequence Similarity 209, Member B 2 3
  • C20orf107 3 4
  • Chromosome 20 Open Reading Frame 107 2
  • Uncharacterized Protein C20orf107 3
  • DJ1153D9.4 3

External Ids for FAM209B Gene

Previous HGNC Symbols for FAM209B Gene

  • C20orf107

Previous GeneCards Identifiers for FAM209B Gene

  • GC20P055109

Summaries for FAM209B Gene

GeneCards Summary for FAM209B Gene

FAM209B (Family With Sequence Similarity 209, Member B) is a Protein Coding gene. An important paralog of this gene is FAM209A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM209B Gene

Genomics for FAM209B Gene

Genomic Location for FAM209B Gene

Chromosome:
20
Start:
56,526,195 bp from pter
End:
56,536,521 bp from pter
Size:
10,327 bases
Orientation:
Plus strand

Genomic View for FAM209B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM209B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM209B Gene

No data available for Regulatory Elements for FAM209B Gene

Proteins for FAM209B Gene

  • Protein details for FAM209B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JX69-F209B_HUMAN
    Recommended name:
    Protein FAM209B
    Protein Accession:
    Q5JX69
    Secondary Accessions:
    • Q3KRB5

    Protein attributes for FAM209B Gene

    Size:
    171 amino acids
    Molecular mass:
    19499 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM209B Gene

Proteomics data for FAM209B Gene at MOPED

Post-translational modifications for FAM209B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM209B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM209B Gene

Domains & Families for FAM209B Gene

Protein Domains for FAM209B Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5JX69

UniProtKB/Swiss-Prot:

F209B_HUMAN :
  • Belongs to the FAM209 family.
Family:
  • Belongs to the FAM209 family.
genes like me logo Genes that share domains with FAM209B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM209B Gene

Function for FAM209B Gene

Phenotypes for FAM209B Gene

GenomeRNAi human phenotypes for FAM209B:
genes like me logo Genes that share phenotypes with FAM209B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM209B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM209B Gene

Localization for FAM209B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM209B Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM209B Gene COMPARTMENTS Subcellular localization image for FAM209B gene
Compartment Confidence
nucleus 5

Gene Ontology (GO) - Cellular Components for FAM209B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM209B: view

Pathways & Interactions for FAM209B Gene

SuperPathways for FAM209B Gene

No Data Available

Interacting Proteins for FAM209B Gene

Gene Ontology (GO) - Biological Process for FAM209B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM209B Gene

Drugs & Compounds for FAM209B Gene

No Compound Related Data Available

Transcripts for FAM209B Gene

mRNA/cDNA for FAM209B Gene

(3) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM209B Gene

Family with sequence similarity 209, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM209B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM209B Gene

No ASD Table

Relevant External Links for FAM209B Gene

GeneLoc Exon Structure for
FAM209B
ECgene alternative splicing isoforms for
FAM209B

Expression for FAM209B Gene

mRNA expression in normal human tissues for FAM209B Gene

mRNA differential expression in normal tissues according to GTEx for FAM209B Gene

This gene is overexpressed in Testis (x36.7) and Whole Blood (x4.5).

Protein differential expression in normal tissues from HIPED for FAM209B Gene

This gene is overexpressed in Testis (62.5) and Ovary (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM209B Gene



SOURCE GeneReport for Unigene cluster for FAM209B Gene Hs.287759

genes like me logo Genes that share expression patterns with FAM209B: view

Protein tissue co-expression partners for FAM209B Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM209B Gene

Orthologs for FAM209B Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM209B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM209B 35
  • 75.35 (n)
  • 61.21 (a)
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 34 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
FAM209B 36
  • 61 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia FAM209B 35
  • 78.97 (n)
  • 69.05 (a)
C24H20ORF106 36
  • 67 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Fam209 35
  • 72.56 (n)
  • 60.37 (a)
Fam209 16
Fam209 36
  • 59 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam209a 35
  • 72.62 (n)
  • 60.12 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 32 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia FAM209B 36
  • 97 (a)
OneToOne
Species with no ortholog for FAM209B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM209B Gene

ENSEMBL:
Gene Tree for FAM209B (if available)
TreeFam:
Gene Tree for FAM209B (if available)

Paralogs for FAM209B Gene

Paralogs for FAM209B Gene

(1) SIMAP similar genes for FAM209B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM209B: view

Variants for FAM209B Gene

Sequence variations from dbSNP and Humsavar for FAM209B Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs2296128 -- 56,536,217(+) CTCCA(C/T)TAAAG reference, synonymous-codon
rs2296129 - 56,536,308(+) GTCCG(A/C)AGTGC reference, missense
rs2296130 -- 56,536,315(+) GTGCA(A/G)AATCT synonymous-codon, reference
rs3209183 - 56,533,561(+) TACTG(A/C)AGTGT missense, reference
rs3938420 -- 56,535,079(+) TAGCC(A/G)GGTGT intron-variant

Variation tolerance for FAM209B Gene

Residual Variation Intolerance Score: 82.21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.34; 76.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM209B Gene

HapMap Linkage Disequilibrium report
FAM209B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM209B Gene

Disorders for FAM209B Gene

Relevant External Links for FAM209B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM209B
genes like me logo Genes that share disorders with FAM209B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM209B Gene

Publications for FAM209B Gene

  1. A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. (PMID: 25130324) Cai D.C. … Hagoort P. (Genes Brain Behav. 2014) 67
  2. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 67
  3. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin- containing protein/p97 during capacitation. (PMID: 12509440) Ficarro S. … Visconti P.E. (J. Biol. Chem. 2003) 67

Products for FAM209B Gene

Sources for FAM209B Gene

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