Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM208B Gene

Aliases for FAM208B Gene

  • Family With Sequence Similarity 208, Member B 2 3
  • C10orf18 3 4
  • Chromosome 10 Open Reading Frame 18 2
  • Protein FAM208B 3
  • BA318E3.2 3
  • KIAA2006 4

External Ids for FAM208B Gene

Previous HGNC Symbols for FAM208B Gene

  • C10orf18

Summaries for FAM208B Gene

GeneCards Summary for FAM208B Gene

FAM208B (Family With Sequence Similarity 208, Member B) is a Protein Coding gene. An important paralog of this gene is FAM208A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM208B Gene

Genomics for FAM208B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM208B Gene

Start:
5,684,838 bp from pter
End:
5,765,779 bp from pter
Size:
80,942 bases
Orientation:
Plus strand

Genomic View for FAM208B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM208B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM208B Gene

No data available for Regulatory Elements for FAM208B Gene

Proteins for FAM208B Gene

  • Protein details for FAM208B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VWN6-F208B_HUMAN
    Recommended name:
    Protein FAM208B
    Protein Accession:
    Q5VWN6
    Secondary Accessions:
    • Q2YD91
    • Q5VWN5
    • Q6ZRQ8
    • Q8IVG4
    • Q9BUZ7
    • Q9H5J9
    • Q9H7A4
    • Q9H996
    • Q9NXA1

    Protein attributes for FAM208B Gene

    Size:
    2430 amino acids
    Molecular mass:
    268843 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA91115.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB14336.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB14993.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC87251.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM208B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM208B Gene

Proteomics data for FAM208B Gene at MOPED

Post-translational modifications for FAM208B Gene

  • Ubiquitination at Lys694 and Lys768
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM208B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM208B Gene

Domains for FAM208B Gene

Protein Domains for FAM208B Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5VWN6

UniProtKB/Swiss-Prot:

F208B_HUMAN :
  • Q5VWN6
Family:
  • Belongs to the FAM208 family.
genes like me logo Genes that share domains with FAM208B: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM208B Gene

Function for FAM208B Gene

Gene Ontology (GO) - Molecular Function for FAM208B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM208B: view

Animal Model Products

miRNA for FAM208B Gene

miRTarBase miRNAs that target FAM208B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM208B Gene

Localization for FAM208B Gene

Gene Ontology (GO) - Cellular Components for FAM208B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with FAM208B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for FAM208B Gene

Pathways for FAM208B Gene

SuperPathways for FAM208B Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM208B Gene

None

No data available for Pathways by source for FAM208B Gene

Transcripts for FAM208B Gene

Unigene Clusters for FAM208B Gene

Family with sequence similarity 208, member B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM208B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM208B Gene

No ASD Table

Relevant External Links for FAM208B Gene

GeneLoc Exon Structure for
FAM208B
ECgene alternative splicing isoforms for
FAM208B

Expression for FAM208B Gene

mRNA expression in normal human tissues for FAM208B Gene

Protein differential expression in normal tissues for FAM208B Gene

This gene is overexpressed in Liver (48.5) and Heart (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM208B Gene

SOURCE GeneReport for Unigene cluster for FAM208B Gene Hs.610717

genes like me logo Genes that share expressions with FAM208B: view

Expression partners for FAM208B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM208B Gene

Orthologs for FAM208B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM208B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM208B 35
  • 73.01 (n)
  • 60.98 (a)
FAM208B 36
  • 60 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM208B 35
  • 77.34 (n)
  • 65.99 (a)
FAM208B 36
  • 58 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC016423 35
  • 73.92 (n)
  • 59.04 (a)
BC016423 16
BC016423 36
  • 59 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM208B 35
  • 98.88 (n)
  • 97.86 (a)
FAM208B 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam208b 35
  • 73.92 (n)
  • 60.02 (a)
oppossum
(Monodelphis domestica)
Mammalia FAM208B 36
  • 47 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM208B 36
  • 33 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM208B 36
  • 28 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 42 (a)
OneToMany
-- 36
  • 23 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii fam208b 36
  • 13 (a)
OneToOne
Species with no ortholog for FAM208B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM208B Gene

ENSEMBL:
Gene Tree for FAM208B (if available)
TreeFam:
Gene Tree for FAM208B (if available)

Paralogs for FAM208B Gene

Paralogs for FAM208B Gene

Selected SIMAP similar genes for FAM208B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM208B: view

Variants for FAM208B Gene

Sequence variations from dbSNP and Humsavar for FAM208B Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs11920 -- 5,763,895(+) GCAGT(A/C)AAGTA intron-variant, utr-variant-3-prime
rs1046393 -- 5,763,881(+) TCTGG(A/G)TTCTT intron-variant, utr-variant-3-prime
rs1057943 -- 5,764,291(-) GAGAT(A/G)GCCTC utr-variant-3-prime
rs1317420 -- 5,725,551(+) CGCTT(A/G)AGGCC intron-variant
rs1418739 -- 5,711,774(-) AGCTG(C/T)ACTTA intron-variant

Relevant External Links for FAM208B Gene

HapMap Linkage Disequilibrium report
FAM208B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM208B Gene

Disorders for FAM208B Gene

No disorders were found for FAM208B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM208B Gene

Publications for FAM208B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  4. NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells. (PMID: 17267499) Katzenellenbogen R.A. … Galloway D.A. (J. Virol. 2007) 3
  5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PMID: 20360068) Hutchins J.R. … Peters J.M. (Science 2010) 3

Products for FAM208B Gene

Sources for FAM208B Gene

Back to Top

Content