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Aliases for FAM208A Gene

Aliases for FAM208A Gene

  • Family With Sequence Similarity 208, Member A 2 3
  • Retinoblastoma-Associated Protein RAP140 3 4
  • CTCL Tumor Antigen Se89-1 3 4
  • C3orf63 3 4
  • Retinoblastoma-Associated Protein 140 3
  • Chromosome 3 Open Reading Frame 63 2
  • Protein FAM208A 3
  • KIAA1105 4
  • RAP140 3
  • Se89-1 3

External Ids for FAM208A Gene

Previous HGNC Symbols for FAM208A Gene

  • C3orf63

Summaries for FAM208A Gene

GeneCards Summary for FAM208A Gene

FAM208A (Family With Sequence Similarity 208, Member A) is a Protein Coding gene. Diseases associated with FAM208A include retinoblastoma. An important paralog of this gene is FAM208B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM208A Gene

Genomics for FAM208A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM208A Gene

56,620,132 bp from pter
56,683,242 bp from pter
63,111 bases
Minus strand

Genomic View for FAM208A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM208A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM208A Gene

No data available for Regulatory Elements for FAM208A Gene

Proteins for FAM208A Gene

  • Protein details for FAM208A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM208A
    Protein Accession:
    Secondary Accessions:
    • A1L3A4
    • B5ME28
    • Q9H2F7
    • Q9UPP7

    Protein attributes for FAM208A Gene

    1670 amino acids
    Molecular mass:
    189032 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG34913.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAI29988.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM208A Gene


neXtProt entry for FAM208A Gene

Proteomics data for FAM208A Gene at MOPED

Post-translational modifications for FAM208A Gene

  • Asn-1105 may be N-glycosylated; however as this position is probably not extracellular, the in vivo relevance is not proven
  • Ubiquitination at Lys197, Lys360, and Lys563
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM208A Gene

No data available for DME Specific Peptides for FAM208A Gene

Domains for FAM208A Gene

Protein Domains for FAM208A Gene


Graphical View of Domain Structure for InterPro Entry



  • Q9UK61
  • Belongs to the FAM208 family.
genes like me logo Genes that share domains with FAM208A: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM208A Gene

Function for FAM208A Gene

Gene Ontology (GO) - Molecular Function for FAM208A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with FAM208A: view

Animal Model Products

CRISPR Products

miRNA for FAM208A Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM208A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM208A Gene

Localization for FAM208A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM208A Gene

Pathways for FAM208A Gene

SuperPathways for FAM208A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM208A Gene


No data available for Pathways by source for FAM208A Gene

Transcripts for FAM208A Gene

Unigene Clusters for FAM208A Gene

Family with sequence similarity 208, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM208A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM208A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b · 17c ^ 18 ^ 19a · 19b ·
SP1: - -
SP2: - - - -
SP3: -
SP6: - -

ExUns: 19c ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24 ^ 25
SP2: -
SP5: - -

Relevant External Links for FAM208A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM208A Gene

mRNA expression in normal human tissues for FAM208A Gene

Protein differential expression in normal tissues for FAM208A Gene

This gene is overexpressed in Testis (22.7) and Peripheral blood mononuclear cells (21.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM208A Gene

SOURCE GeneReport for Unigene cluster for FAM208A Gene Hs.116877

genes like me logo Genes that share expressions with FAM208A: view

Expression partners for FAM208A Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM208A Gene

Orthologs for FAM208A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM208A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM208A 35
  • 92.51 (n)
  • 90.03 (a)
FAM208A 36
  • 81 (a)
(Canis familiaris)
Mammalia FAM208A 35
  • 93.86 (n)
  • 92.62 (a)
FAM208A 36
  • 83 (a)
(Mus musculus)
Mammalia D14Abb1e 35
  • 86.87 (n)
  • 82.86 (a)
D14Abb1e 16
D14Abb1e 36
  • 82 (a)
(Pan troglodytes)
Mammalia FAM208A 35
  • 98.88 (n)
  • 98.53 (a)
FAM208A 36
  • 89 (a)
(Rattus norvegicus)
Mammalia Fam208a 35
  • 86.42 (n)
  • 82.78 (a)
(Monodelphis domestica)
Mammalia FAM208A 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia FAM208A 36
  • 73 (a)
(Gallus gallus)
Aves FAM208A 35
  • 70.24 (n)
  • 64.15 (a)
FAM208A 36
  • 58 (a)
(Anolis carolinensis)
Reptilia FAM208A 36
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam208a 35
  • 56.27 (n)
  • 48.65 (a)
(Danio rerio)
Actinopterygii fam208ab 35
  • 53.41 (n)
  • 43.89 (a)
CABZ01044611.1 36
  • 26 (a)
fam208ab 36
  • 26 (a)
Species with no ortholog for FAM208A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM208A Gene

Gene Tree for FAM208A (if available)
Gene Tree for FAM208A (if available)

Paralogs for FAM208A Gene

Paralogs for FAM208A Gene Pseudogenes for FAM208A Gene

genes like me logo Genes that share paralogs with FAM208A: view

Variants for FAM208A Gene

Sequence variations from dbSNP and Humsavar for FAM208A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs873840 -- 56,684,776(+) TCGAA(A/T)CAATT upstream-variant-2KB
rs953539 -- 56,657,936(-) AGCCA(C/G)TTGTC intron-variant
rs953540 -- 56,657,760(-) cattt(A/G)tttag intron-variant
rs958755 - 56,682,894(+) TTTGT(G/T)GGGAG reference, missense
rs1054092 -- 56,675,785(-) TTTAG(A/G)AGTAT intron-variant

Relevant External Links for FAM208A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM208A Gene

Disorders for FAM208A Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for FAM208A Gene in MalaCards »

(1) Diseases for FAM208A Gene including...

genes like me logo Genes that share disorders with FAM208A: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM208A Gene

Publications for FAM208A Gene

  1. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 2 3 4
  2. Serological detection of cutaneous T-cell lymphoma-associated antigens. (PMID: 11149944) Eichmueller S. … Schadendorf D. (Proc. Natl. Acad. Sci. U.S.A. 2001) 2 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Identification and cloning of the cDNA of a Rb-associated protein RAP140a. (PMID: 18726359) Li Q. … Ao S. (Sci. China, Ser. C, Life Sci. 2000) 3 4
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for FAM208A Gene

Sources for FAM208A Gene

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