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Aliases for FAM206A Gene

Aliases for FAM206A Gene

  • Family With Sequence Similarity 206, Member A 2 3
  • Protein FAM206A 3 4
  • C9orf6 3 4
  • Chromosome 9 Open Reading Frame 6 2
  • Protein Simiate 3
  • CG-8 3

External Ids for FAM206A Gene

Previous Symbols for FAM206A Gene

  • C9orf6

Summaries for FAM206A Gene

GeneCards Summary for FAM206A Gene

FAM206A (Family With Sequence Similarity 206, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM206A Gene

Genomics for FAM206A Gene

Genomic Location for FAM206A Gene

Start:
108,934,181 bp from pter
End:
108,950,744 bp from pter
Size:
16,564 bases
Orientation:
Plus strand

Genomic View for FAM206A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM206A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM206A Gene

No data available for Regulatory Elements for FAM206A Gene

Proteins for FAM206A Gene

  • Protein details for FAM206A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX38-F206A_HUMAN
    Recommended name:
    Protein Simiate
    Protein Accession:
    Q9NX38
    Secondary Accessions:
    • Q5JTR0
    • Q5JTR1

    Protein attributes for FAM206A Gene

    Size:
    181 amino acids
    Molecular mass:
    20378 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Depletion of FAM206A/Simiate by siRNA or neutralizing antibodies results in cell death within a few hours.
    SequenceCaution:
    • Sequence=CAI39468.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI39469.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for FAM206A Gene

Proteomics data for FAM206A Gene at MOPED

Post-translational modifications for FAM206A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM206A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM206A Gene

Domains for FAM206A Gene

Protein Domains for FAM206A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F206A_HUMAN
Family:
  • Belongs to the FAM206 family.:
    • Q9NX38
genes like me logo Genes that share domains with FAM206A: view

No data available for Gene Families for FAM206A Gene

Function for FAM206A Gene

Gene Ontology (GO) - Molecular Function for FAM206A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 15607035
genes like me logo Genes that share ontologies with FAM206A: view

miRNA for FAM206A Gene

miRTarBase miRNAs that target FAM206A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM206A Gene

Localization for FAM206A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM206A Gene

Nucleus speckle. Note=Localizes to somata and dendrites in cortical neurons. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for FAM206A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0016607 nuclear speck IEA --
genes like me logo Genes that share ontologies with FAM206A: view

Pathways for FAM206A Gene

SuperPathways for FAM206A Gene

No Data Available

Interacting Proteins for FAM206A Gene

Gene Ontology (GO) - Biological Process for FAM206A Gene

None

No data available for Pathways by source for FAM206A Gene

Transcripts for FAM206A Gene

Unigene Clusters for FAM206A Gene

Family with sequence similarity 206, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM206A Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d
SP1: -
SP2:
SP3: - -
SP4: - - -

Relevant External Links for FAM206A Gene

GeneLoc Exon Structure for
FAM206A
ECgene alternative splicing isoforms for
FAM206A

Expression for FAM206A Gene

mRNA expression in normal human tissues for FAM206A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM206A Gene

SOURCE GeneReport for Unigene cluster for FAM206A Gene Hs.29276

genes like me logo Genes that share expressions with FAM206A: view

Orthologs for FAM206A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAM206A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM206A 36
  • 99.45 (n)
  • 98.9 (a)
FAM206A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM206A 36
  • 90.61 (n)
  • 92.82 (a)
FAM206A 37
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM206A 36
  • 92.55 (n)
  • 97.06 (a)
FAM206A 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia BC026590 36
  • 86.59 (n)
  • 87.93 (a)
BC026590 16
BC026590 37
  • 80 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM206A 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM206A 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam206a 36
  • 88.26 (n)
  • 91.48 (a)
chicken
(Gallus gallus)
Aves FAM206A 36
  • 74.85 (n)
  • 76.69 (a)
FAM206A 37
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM206A 37
  • 73 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.3630 36
tropical clawed frog
(Silurana tropicalis)
Amphibia fam206a 36
  • 71.63 (n)
  • 74.4 (a)
Str.1518 36
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.6676 36
zebrafish
(Danio rerio)
Actinopterygii fam206a 36
  • 68.65 (n)
  • 72.02 (a)
fam206a 37
  • 68 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002455 36
  • 48.58 (n)
  • 43.14 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9288 36
  • 48.53 (n)
  • 48.3 (a)
CG9288 37
  • 33 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F54F2.7 37
  • 27 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G75980 36
  • 46.84 (n)
  • 33.33 (a)
rice
(Oryza sativa)
Liliopsida Os02g0120400 36
  • 47.26 (n)
  • 32.84 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 44 (a)
OneToOne
Species with no ortholog for FAM206A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM206A Gene

ENSEMBL:
Gene Tree for FAM206A (if available)
TreeFam:
Gene Tree for FAM206A (if available)

Paralogs for FAM206A Gene

No data available for Paralogs for FAM206A Gene

Variants for FAM206A Gene

Sequence variations from dbSNP and Humsavar for FAM206A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs838819 -- 108,938,885(-) AAAGT(A/G)TGGGA intron-variant
rs1046649 -- 108,940,921(+) ATATC(A/C)CTGtt utr-variant-3-prime
rs3177467 -- 108,940,955(+) CAGAA(A/G)AAATC utr-variant-3-prime
rs7027263 -- 108,937,289(+) CACTC(A/G)GTTAT intron-variant
rs10979615 -- 108,936,509(+) TGAAC(C/T)TTAGA intron-variant

Relevant External Links for FAM206A Gene

HapMap Linkage Disequilibrium report
FAM206A

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM206A Gene

Disorders for FAM206A Gene

No disorders were found for FAM206A Gene.

No data available for UniProtKB/Swiss-Prot for FAM206A Gene

Publications for FAM206A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. (PMID: 15607035) Ahn J. … Hoe K.-L. (J. Biochem. Mol. Biol. 2004) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for FAM206A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM206A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM206A
    • Block miRNA regulation of FAM206A using miScript Target Protectors

    Sources for FAM206A Gene

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