FAM206A Gene
protein-coding GIFtS : 41
GCID: GC09 P111697
family with sequence similarity 206, member A (Previous name: chromosome 9 open reading frame 6 ) (Previous symbol: C9orf6 )
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Aliasesfor FAM206A gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Family With Sequence Similarity 206, Member A 1 2 C9orf61 2 3 CG-81 2 FLJ204571 Chromosome 9 Open Reading Frame 61 Protein FAM206A2
Export aliases for FAM206A gene to outside databases
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Summariesfor FAM206A gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor FAM206A gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000009.11 NC_018920.1 NT_008470.19 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for FAM206A Other transcription factors Search SABiosciences Chromatin IP Primers for FAM206A Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM206A
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q31.3 Ensembl cytogenetic band: 9q31.3 HGNC cytogenetic band: 9q31 FAM206A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09P111697: view genomic region
(about GC identifiers )
Start:
111,696,461 bp from pter
End:
111,713,024 bp from pter
Size:
16,564 bases
Orientation:
plus strand
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Proteinsfor FAM206A gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: F206A_HUMAN, Q9NX38 (See
protein sequence )Recommended Name: Protein FAM206A Size : 181 amino acids; 20378 Da
Sequence caution : Sequence=CAI39468.1; Type=Erroneous gene model prediction; Sequence=CAI39469.1; Type=Erroneous genemodel prediction;
Secondary accessions : Q5JTR0 Q5JTR1Explore the universe of human proteins at neXtProt for FAM206A: NX_Q9NX38 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q9NX38 FAM206A Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_060302.1 ENSEMBL proteins: ENSP00000363753 ENSP00000363754 ENSP00000398018 Human Recombinant Protein Products for FAM206A: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005960 glycine cleavage complex
IEA --
FAM206A for ontologies About GeneDecksing FAM206A Antibody Products: Assay Products for FAM206A:
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Protein
Domains / Familiesfor FAM206A gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FAM206A for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q9NX38 ProtoNet protein and cluster: Q9NX38
UniProtKB/Swiss-Prot: F206A_HUMAN, Q9NX38 Similarity : Belongs to the FAM206 family
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Functionfor FAM206A gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206A (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206AOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript Custom all cDNA clones Services for FAM206A Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM206A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM206A
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM206A
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Pathways & Interactionsfor FAM206A gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM206A STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)4 Interacting proteins for FAM206A (Q9NX38 3 ENSP00000363753 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 1 biological process term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006546 glycine catabolic process
IEA --
FAM206A for ontologies About GeneDecksing
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Drugs & Compoundsfor FAM206A gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for FAM206A Search CenterWatch for drugs/clinical trials and news about FAM206A / F206A
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Transcriptsfor FAM206A gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for FAM206A gene: NM_017832.3 Unigene Cluster for FAM206A:
Family with sequence similarity 206, member A Hs.29276 [show with all ESTs ] Unigene Representative Sequence: BC051827 4 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000322940 (uc004bdn.3 uc010mtr.3 ) ENST00000466200 ENST00000374624 ENST00000445175 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206A (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206AOriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript Custom all cDNA clones Services for FAM206A DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM206A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM206A
Additional cDNA sequence: AF153417.1 AK000464.1 AK310297.1 BC015795.1 BC051827.1
9 DOTS entries : DT.455449 DT.448141
DT.92003217 DT.121189478 DT.75123070 DT.208637 DT.40114272 DT.97801139 DT.100833869 24/115 AceView cDNA sequences (see all 115 ):
AK000464 N23764 AA548370 AI363483 BM931151 CR609752 AI086660 AA505864 BM684603 CB140062 AI242697 AA427780 AA952945 AI863836 AA505845 AI339940 AA758524 CR601308 BC051827 AA905233 BU850224 AA829516 CD251887 BQ574464 GeneLoc Exon Structure 4 Alternative Splicing Database (ASD) splice patterns (SP) for FAM206A About this scheme ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d SP1 :       -                   SP2 :                         SP3 :       -     -               SP4 :       -   -   -              
ECgene alternative splicing isoforms for FAM206A
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Expression for FAM206A gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section FAM206A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TCAATATCACAbout this image FAM206A expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
Stem Cell Differentiation: 1 LifeMap Cell Name Category Posterior foregut-like cells (A scalable, suspensi... )Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See FAM206A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FAM206A SOURCE GeneReport for Unigene cluster: Hs.29276 SABiosciences Custom PCR Arrays for FAM206A Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM206ABrowse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM206A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM206A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM206A In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM206A
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Orthologsfor FAM206A gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM206A gene from 9/25 species (see all 25 ) About this table
ENSEMBL Gene Tree for FAM206A (if available)TreeFam Gene Tree for FAM206A (if available)
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Paralogsfor FAM206A gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section --
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Genomic Variantsfor FAM206A gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 9 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for FAM206A (111696461 - 111713024 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for FAM206A: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM206A
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Disorders
/ Diseasesfor FAM206A gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
FAM206A for disorders About GeneDecksing 2 diseases for FAM206A : About MalaCards hepatitis c hepatitis Export disorders for FAM206A gene to outside databases
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Publicationsfor FAM206A gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for FAM206A gene integrated from 9 sources : (articles sorted by number of sources associating them with FAM206A) Utopia : connect your pdf to the dynamic world of online information
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983) 1 Kim W....Gygi S.P. (2011) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965) 1 Lamesch P.... Vidal M. (2007) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 2 Ota T.... Sugano S. (2004) DNA sequence and analysis of human chromosome 9. (PubMed id 15164053) 2 Humphray S.J.... Dunham I. (2004) Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. (PubMed id 15607035) 1 Ahn J.... Hoe K.-L. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id ) 2 Aoki H.... Hino O. (2000)
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External Searches for FAM206A gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FAM206A gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing FAM206A gene
(According to HUGE )
About This Section --
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Specialized Databases showing FAM206A gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for FAM206A Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for FAM206A gene: Search GeneIP for patents involving FAM206A GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FAM206A gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for FAM206A OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for FAM206A OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM206A OriGene Protein Over-expression Lysate for FAM206A Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for FAM206A Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206A OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM206A Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for FAM206A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for FAM206A OriGene Custom Protein Services for FAM206A OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM206A QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM206A QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM206A QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat FAM206A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM206A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM206A
Search Tocris compounds for FAM206A
FAM206A Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM206A
Search ThermoFisher Antibodies for FAM206A
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM206A
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Aliases for FAM206A
Databases for FAM206A
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Function for FAM206A
Genomic Views for FAM206A
Intellectual Property for FAM206A
Orthologs for FAM206A
Paralogs for FAM206A
Pathways / Interactions for FAM206A
Products for FAM206A
Proteins for FAM206A
Publications for FAM206A
Search Box for FAM206A
Summaries for FAM206A
Transcripts for FAM206A
Variants for FAM206A
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