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Aliases for FAM205A Gene

Aliases for FAM205A Gene

  • Family With Sequence Similarity 205 Member A 2 3 5
  • Family With Sequence Similarity 205, Member A 2 3
  • C9orf144B 3 4
  • Transmembrane Protein C9orf144B 3

External Ids for FAM205A Gene

Summaries for FAM205A Gene

GeneCards Summary for FAM205A Gene

FAM205A (Family With Sequence Similarity 205 Member A) is a Protein Coding gene. An important paralog of this gene is FAM205C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM205A Gene

Genomics for FAM205A Gene

Regulatory Elements for FAM205A Gene

Enhancers for FAM205A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM205A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM205A Gene

Chromosome:
9
Start:
34,723,053 bp from pter
End:
34,729,538 bp from pter
Size:
6,486 bases
Orientation:
Minus strand

Genomic View for FAM205A Gene

Genes around FAM205A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM205A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM205A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM205A Gene

Proteins for FAM205A Gene

  • Protein details for FAM205A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU69-F205A_HUMAN
    Recommended name:
    Protein FAM205A
    Protein Accession:
    Q6ZU69
    Secondary Accessions:
    • A8MVW7

    Protein attributes for FAM205A Gene

    Size:
    1335 amino acids
    Molecular mass:
    148096 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC86357.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM205A Gene

Proteomics data for FAM205A Gene at MOPED

Post-translational modifications for FAM205A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM205A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM205A Gene

Domains & Families for FAM205A Gene

Protein Domains for FAM205A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM205A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6ZU69

UniProtKB/Swiss-Prot:

F205A_HUMAN :
  • Belongs to the FAM205 family.
Family:
  • Belongs to the FAM205 family.
genes like me logo Genes that share domains with FAM205A: view

No data available for Gene Families for FAM205A Gene

Function for FAM205A Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM205A Gene

Localization for FAM205A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM205A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM205A Gene COMPARTMENTS Subcellular localization image for FAM205A gene
Compartment Confidence
nucleus 5
golgi apparatus 3
plasma membrane 3
cytosol 2
endoplasmic reticulum 1
extracellular 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM205A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM205A: view

Pathways & Interactions for FAM205A Gene

SuperPathways for FAM205A Gene

No Data Available

Interacting Proteins for FAM205A Gene

Gene Ontology (GO) - Biological Process for FAM205A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM205A Gene

Drugs & Compounds for FAM205A Gene

No Compound Related Data Available

Transcripts for FAM205A Gene

mRNA/cDNA for FAM205A Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM205A Gene

Family with sequence similarity 205, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM205A Gene

No ASD Table

Relevant External Links for FAM205A Gene

GeneLoc Exon Structure for
FAM205A
ECgene alternative splicing isoforms for
FAM205A

Expression for FAM205A Gene

mRNA expression in normal human tissues for FAM205A Gene

mRNA differential expression in normal tissues according to GTEx for FAM205A Gene

This gene is overexpressed in Testis (x48.5).

Protein differential expression in normal tissues from HIPED for FAM205A Gene

This gene is overexpressed in Testis (57.3) and Ovary (11.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM205A Gene



SOURCE GeneReport for Unigene cluster for FAM205A Gene Hs.522093

genes like me logo Genes that share expression patterns with FAM205A: view

Protein tissue co-expression partners for FAM205A Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM205A Gene

Orthologs for FAM205A Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM205A Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia FAM205A 35
  • 78.21 (n)
  • 64.68 (a)
FAM205A 36
  • 64 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC100862324 35
  • 67.13 (n)
  • 47.3 (a)
Fam205a4 16
BC049635 36
  • 31 (a)
OneToMany
CR974586.1 36
  • 43 (a)
OneToMany
CR974586.7 36
  • 45 (a)
OneToMany
CT868723.2 36
  • 47 (a)
OneToMany
FAM205A 36
  • 45 (a)
OneToMany
Gm10600 36
  • 36 (a)
OneToMany
Gm12394 36
  • 46 (a)
OneToMany
Gm12429 36
  • 45 (a)
OneToMany
Gm13298 36
  • 45 (a)
OneToMany
Gm20938 36
  • 45 (a)
OneToMany
Gm21093 36
  • 47 (a)
OneToMany
Gm21598 36
  • 45 (a)
OneToMany
Gm2163 36
  • 44 (a)
OneToMany
Gm3883 36
  • 47 (a)
OneToMany
GM7819 36
  • 44 (a)
OneToMany
OTTMUSG00000011338 36
  • 47 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC746223 35
  • 98.75 (n)
  • 97.6 (a)
FAM205A 36
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam205a 35
  • 67.2 (n)
  • 48.43 (a)
cow
(Bos Taurus)
Mammalia -- 36
  • 62 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia FAM205A 36
  • 35 (a)
OneToOne
Species with no ortholog for FAM205A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM205A Gene

ENSEMBL:
Gene Tree for FAM205A (if available)
TreeFam:
Gene Tree for FAM205A (if available)

Paralogs for FAM205A Gene

Paralogs for FAM205A Gene

(1) SIMAP similar genes for FAM205A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for FAM205A Gene

genes like me logo Genes that share paralogs with FAM205A: view

Variants for FAM205A Gene

Sequence variations from dbSNP and Humsavar for FAM205A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1697616 -- 34,725,050(+) AGGTC(A/C/G/T)GGGTC reference, synonymous-codon
rs1697617 -- 34,724,990(-) CAGGC(C/T)TTACC reference, synonymous-codon
rs1755267 -- 34,725,044(+) TGATG(C/T)AGGTC reference, synonymous-codon
rs1755268 -- 34,725,072(+) GCAGT(A/T)CCAGG reference, missense
rs1810820 -- 34,726,527(-) GATGA(C/T)GCAGA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for FAM205A Gene

Variant ID Type Subtype PubMed ID
nsv831544 CNV Gain 17160897
nsv893040 CNV Gain 21882294
nsv509301 CNV Insertion 20534489
esv2738389 CNV Deletion 23290073
dgv1337e199 CNV Deletion 23128226

Variation tolerance for FAM205A Gene

Gene Damage Index Score: 22.70; 99.46% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM205A Gene

Human Gene Mutation Database (HGMD)
FAM205A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM205A Gene

Disorders for FAM205A Gene

Relevant External Links for FAM205A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM205A

No disorders were found for FAM205A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM205A Gene

Publications for FAM205A Gene

  1. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3 67
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for FAM205A Gene

Sources for FAM205A Gene

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