FAM204A Gene
protein-coding GIFtS: 38
GCID: GC10M120065
|
|
family with sequence similarity 204, member A(Previous name: chromosome 10 open reading frame 84 )
(Previous symbol: C10orf84)
| |
Aliases
for FAM204A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 204, Member A1 2 | | C10orf841 2 3 | | BA319I23.11 | | FLJ131881 | | Chromosome 10 Open Reading Frame 841 | | Protein FAM204A2 |
Export aliases for FAM204A gene to outside databases |
Summaries
for FAM204A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM204A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_030059.13
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM204A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM204A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM204A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q26.11 Ensembl cytogenetic band: 10q26.11 HGNC cytogenetic band: 10q26.12FAM204A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10M120065: view genomic region
(about GC identifiers)
Start:
|
120,065,401 bp from pter |
End:
|
120,101,840 bp from pter |
Size:
|
36,440 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM204A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F204A_HUMAN, Q9H8W3 (See
protein sequence)Recommended Name: Protein FAM204A Size: 233 amino acids; 27021 Da
Secondary accessions: D3DRC6 Q5T373 Q9H5V5Explore the universe of human proteins at neXtProt for FAM204A: NX_Q9H8W3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H8W3
FAM204A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001128144.1 NP_071346.1
ENSEMBL proteins: ENSP00000358183 ENSP00000432701 ENSP00000358170 ENSP00000358168
Human Recombinant Protein Products:
FAM204A Antibody Products:
Assay Products for FAM204A: |
Protein
Domains /
Families
for FAM204A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9H8W3 |
Function
for FAM204A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM204A | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM204A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM204A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM204A |
|
Pathways & Interactions
for FAM204A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM204A
1 Interacting protein for FAM204A (Q9H8W33) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for FAM204A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM204A
Search CenterWatch for drugs/clinical trials and news about FAM204A / F204A
|
Transcripts
for FAM204A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM204A gene (2 alternative transcripts): NM_001134672.1 NM_022063.2 Unigene Cluster for FAM204A: Family with sequence similarity 204, member A Hs.372309 [show with all ESTs]Unigene Representative Sequence: NM_02206311 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369183(uc001ldo.2 uc010qss.1) ENST00000467890 ENST00000488152
ENST00000491416 ENST00000470476 ENST00000469758 ENST00000369172 ENST00000469780
ENST00000369170 ENST00000490048 ENST00000487269
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM204A | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM204A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM204A |
Additional cDNA sequence: AK023250.1 AK026630.1 BC023577.2 CR457304.1 11 DOTS entries: DT.413545 DT.75198033 DT.121270533 DT.100747409 DT.100806881 DT.86848354 DT.91748725 DT.75125231 DT.95080064 DT.95080077 DT.95080073 24/188 AceView cDNA sequences (see all 188): AI522305 CB529126 AW204649 AI970942 AI685716 AU279826 CR616981 AI147026 AA331915 CA311012 AI433474 BF508118 BM988182 BP366578 CD365247 AW451054 BU541600 BM837313 AI420041 AW337808 BQ893798 BP345807 CR591945 BX109859
GeneLoc Exon Structure
5/11 Alternative Splicing Database (ASD) splice patterns (SP) for FAM204A (see all 11) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | - | | | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM204A
|
Expression
for FAM204A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM204A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM204A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM204A
SOURCE GeneReport for Unigene cluster: Hs.372309
SABiosciences Custom PCR Arrays for FAM204A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM204A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM204A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM204A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM204A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM204A |
Orthologs
for FAM204A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM204A gene from 4/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
D19Ertd737e1 , 5 |
DNA segment, Chr 19, ERATO Doi 737, expressed1, 5 |
85.12(n)1
79.83(a)1 |
|
19 (56.52 cM)5
765391 NM_029648.61 NP_083924.21
601985865 |
chicken
(Gallus gallus) |
Aves |
FAM204A1 |
family with sequence similarity 204, member A |
64.95(n)
56.65(a) |
|
423925 XM_421785.3 XP_421785.2 |
lizard
(Anolis carolinensis) |
Reptilia |
FAM204A6 |
-- |
56(a) |
1 ↔ 1 |
GL343206.1(396352-419238) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.188112 |
Transcribed sequence with weak similarity to protein more |
79.31(n) |
|
BQ618274.1 |
ENSEMBL Gene Tree for FAM204A (if available)
TreeFam Gene Tree for FAM204A (if available) |
Paralogs
for FAM204A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM204A gene
1 SIMAP similar gene for FAM204A using alignment to 3 protein entries: F204A_HUMAN (see all proteins):FLJ13188
FAM204A for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for FAM204A
PGOHUM00000248441 PGOHUM00000257966 PGOHUM00000244384
|
Genomic Variants
for FAM204A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 10 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM204A (120065401 - 120101840 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM204A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM204A |
|
Disorders
/ Diseases
for FAM204A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM204A for disorders About GeneDecksing
1  disease for FAM204A: About MalaCardsalzheimer's disease
Export disorders for FAM204A gene to outside databases
|
Publications
for FAM204A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM204A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM204A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
- The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)
|
External Searches for FAM204A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM204A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM204A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM204A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM204A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM204A gene:
Search GeneIP for patents involving FAM204A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM204A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM204A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM204A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM204A | | | OriGene Protein Over-expression Lysate for FAM204A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM204A | | OriGene 3'-UTR Clone for FAM204A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM204A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM204A | | OriGene Custom Protein Services for FAM204A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM204A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM204A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM204A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM204A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM204A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM204A |
| |
 |  |  |  | |
| | | | Search Tocris compounds for FAM204A |
| |  |  |  |  | | | | |
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 |
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 | | | FAM204A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM204A |
|  |  |  | | | | ThermoFisher Antibodies for FAM204A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM204A |
|
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