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Aliases for FAM204A Gene

Aliases for FAM204A Gene

  • Family With Sequence Similarity 204 Member A 2 3 5
  • C10orf84 3 4
  • Family With Sequence Similarity 204, Member A 2
  • Chromosome 10 Open Reading Frame 84 2
  • Protein FAM204A 3
  • BA319I23.1 3

External Ids for FAM204A Gene

Previous HGNC Symbols for FAM204A Gene

  • C10orf84

Previous GeneCards Identifiers for FAM204A Gene

  • GC10M120065

Summaries for FAM204A Gene

GeneCards Summary for FAM204A Gene

FAM204A (Family With Sequence Similarity 204 Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM204A Gene

Genomics for FAM204A Gene

Regulatory Elements for FAM204A Gene

Enhancers for FAM204A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10F119312 1.7 FANTOM5 Ensembl ENCODE 9.7 -974.0 -973973 7.8 HDGF MLX ZFP64 ARID4B SIN3A YBX1 FEZF1 DMAP1 YY1 SLC30A9 SEC23IP FAM204A LOC105378511 GC10P119246
GH10F117966 1.3 VISTA 9.7 +375.4 375359 1.4 HDGF PKNOX1 MLX ARID4B SIN3A DMAP1 FEZF1 ZNF2 ZNF48 YY1 ENSG00000231104 RAB11FIP2 FAM204A LOC105378504
GH10F118958 1 Ensembl ENCODE 9.7 -618.2 -618183 3.6 JUN MAX ZNF316 ZNF239 RCOR1 FOS NFE2 MAFK TCF7L2 NFE2L2 ENSG00000229272 FAM204A SFXN4 LDHAP5 GC10P119001
GH10F118373 0.6 ENCODE 11.3 -31.7 -31656 0.2 JUND PRDM10 ZNF384 FOS MNT ZIC2 FAM204A LINC00867 GC10P118488
GH10F117502 0.6 ENCODE 9.7 +839.0 839008 0.8 SOX5 CTCF TRIM22 REST RAD21 HNF1A POLR2A SMARCA4 ZNF239 FAM204A PDZD8 GC10P117520 LOC105378503
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM204A on UCSC Golden Path with GeneCards custom track

Promoters for FAM204A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000007190 328 2001 PKNOX1 ARID4B SIN3A GLI4 ZNF48 ETS1 YY1 GLIS2 FOS SP3

Genomic Location for FAM204A Gene

Chromosome:
10
Start:
118,297,930 bp from pter
End:
118,342,328 bp from pter
Size:
44,399 bases
Orientation:
Minus strand

Genomic View for FAM204A Gene

Genes around FAM204A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM204A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM204A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM204A Gene

Proteins for FAM204A Gene

  • Protein details for FAM204A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H8W3-F204A_HUMAN
    Recommended name:
    Protein FAM204A
    Protein Accession:
    Q9H8W3
    Secondary Accessions:
    • D3DRC6
    • Q5T373
    • Q9H5V5

    Protein attributes for FAM204A Gene

    Size:
    233 amino acids
    Molecular mass:
    27021 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM204A Gene

Post-translational modifications for FAM204A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM204A Gene

No data available for DME Specific Peptides for FAM204A Gene

Domains & Families for FAM204A Gene

Protein Domains for FAM204A Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM204A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM204A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FAM204A Gene

Function for FAM204A Gene

Phenotypes for FAM204A Gene

GenomeRNAi human phenotypes for FAM204A:
genes like me logo Genes that share phenotypes with FAM204A: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM204A Gene

Localization for FAM204A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM204A gene
Compartment Confidence
nucleus 4
cytoskeleton 2
plasma membrane 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM204A Gene

Pathways & Interactions for FAM204A Gene

SuperPathways for FAM204A Gene

No Data Available

Interacting Proteins for FAM204A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000358170%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q9H8W3-F204A_HUMAN ENSP00000358170 for FAM204A Gene via MINT STRING IID

Gene Ontology (GO) - Biological Process for FAM204A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM204A Gene

Transcripts for FAM204A Gene

Unigene Clusters for FAM204A Gene

Family with sequence similarity 204, member A:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM204A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
SP1: - - - -
SP2: - - - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6: - - - - -
SP7: -
SP8: - - -
SP9: -
SP10: - -
SP11: -

Relevant External Links for FAM204A Gene

GeneLoc Exon Structure for
FAM204A
ECgene alternative splicing isoforms for
FAM204A

Expression for FAM204A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM204A Gene

Protein differential expression in normal tissues from HIPED for FAM204A Gene

This gene is overexpressed in Uterus (46.4), Adipocyte (13.1), and Blymphocyte (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FAM204A Gene



Protein tissue co-expression partners for FAM204A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM204A Gene:

FAM204A

SOURCE GeneReport for Unigene cluster for FAM204A Gene:

Hs.372309
genes like me logo Genes that share expression patterns with FAM204A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM204A Gene

Orthologs for FAM204A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM204A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM204A 34 35
  • 99.57 (n)
dog
(Canis familiaris)
Mammalia FAM204A 34 35
  • 88.13 (n)
cow
(Bos Taurus)
Mammalia FAM204A 34 35
  • 87.27 (n)
mouse
(Mus musculus)
Mammalia D19Ertd737e 34 35
  • 85.12 (n)
Fam204a 16
rat
(Rattus norvegicus)
Mammalia Fam204a 34
  • 83.69 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 65 (a)
OneToMany
-- 35
  • 65 (a)
OneToMany
-- 35
  • 64 (a)
OneToMany
-- 35
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia FAM204A 35
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM204A 34 35
  • 63.77 (n)
lizard
(Anolis carolinensis)
Reptilia FAM204A 35
  • 55 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii fam204a 34 35
  • 56.98 (n)
Dr.18811 34
sea squirt
(Ciona savignyi)
Ascidiacea CSA.900 35
  • 29 (a)
OneToOne
Species where no ortholog for FAM204A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM204A Gene

ENSEMBL:
Gene Tree for FAM204A (if available)
TreeFam:
Gene Tree for FAM204A (if available)

Paralogs for FAM204A Gene

(1) SIMAP similar genes for FAM204A Gene using alignment to 3 proteins:

Pseudogenes.org Pseudogenes for FAM204A Gene

genes like me logo Genes that share paralogs with FAM204A: view

No data available for Paralogs for FAM204A Gene

Variants for FAM204A Gene

Sequence variations from dbSNP and Humsavar for FAM204A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1061498 -- 118,342,906(+) TGCTT(A/G)GGGAA upstream-variant-2KB
rs10886222 -- 118,323,026(+) TTACC(C/T)TTTCT intron-variant
rs1101555 -- 118,332,340(+) TCTGA(A/G)AATAA intron-variant
rs111356081 -- 118,309,499(+) AAGAG(A/G)TGAAC nc-transcript-variant, utr-variant-3-prime
rs111701062 -- 118,341,485(+) AATGT(G/T)TTCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM204A Gene

Variant ID Type Subtype PubMed ID
esv2741561 CNV deletion 23290073
esv2741572 CNV deletion 23290073
esv2741584 CNV deletion 23290073
esv3624687 CNV loss 21293372

Variation tolerance for FAM204A Gene

Residual Variation Intolerance Score: 40% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.34; 7.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM204A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM204A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM204A Gene

Disorders for FAM204A Gene

Relevant External Links for FAM204A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM204A

No disorders were found for FAM204A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM204A Gene

Publications for FAM204A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3 64

Products for FAM204A Gene

Sources for FAM204A Gene

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