FAM203A Gene
protein-coding GIFtS: 41
GCID: GC08P145194
|
|
family with sequence similarity 203, member A(Previous name: chromosome 8 open reading frame 30A )
(Previous symbol: C8orf30A)
| |
Aliases
for FAM203A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 203, Member A1 2 | | FLJ409071 | | C8orf30A1 2 3 | | LOC512361 | | Brain Protein 162 3 | | Chromosome 8 Open Reading Frame 30A1 | | BRP162 3 | | Protein FAM203A2 |
Export aliases for FAM203A gene to outside databases |
Summaries
for FAM203A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM203A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NT_008046.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM203A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM203A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM203A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3FAM203A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P145194: view genomic region
(about GC identifiers)
Start:
|
145,192,672 bp from pter |
End:
|
145,195,746 bp from pter |
Size:
|
3,075 bases |
Orientation:
|
plus strand |
|
Proteins
for FAM203A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F203A_HUMAN, Q9BTY7 (See
protein sequence)Recommended Name: Protein FAM203A Size: 390 amino acids; 42129 DaExplore the universe of human proteins at neXtProt for FAM203A: NX_Q9BTY7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BTY7
FAM203A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_057542.2
ENSEMBL proteins: ENSP00000321320 ENSP00000431970
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
FAM203A for ontologies About GeneDecksing
FAM203A Antibody Products:
Assay Products for FAM203A: |
Protein
Domains /
Families
for FAM203A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM203A for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BTY7ProtoNet protein and cluster: Q9BTY7 UniProtKB/Swiss-Prot: F203A_HUMAN, Q9BTY7Similarity: Belongs to the FAM203 family |
Function
for FAM203A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM203A (NM_016458) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM203A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM203A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM203A |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
FAM203A for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for FAM203A:
|
Pathways & Interactions
for FAM203A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM203A
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/14 Interacting proteins for FAM203A (Q9BTY72, 3 ENSP000003213204) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
FAM203A for ontologies About GeneDecksing
|
Drugs & Compounds
for FAM203A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM203A
Search CenterWatch for drugs/clinical trials and news about FAM203A / F203A
|
Transcripts
for FAM203A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM203A gene: NM_016458.2 Unigene Cluster for FAM203A: Family with sequence similarity 203, member A Hs.300224 [show with all ESTs]Unigene Representative Sequence: NM_0164586 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000347708(uc010mfs.3) ENST00000533266(uc003zbf.3) ENST00000530074
ENST00000530409 ENST00000525101 ENST00000534255
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM203A (NM_016458) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM203A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM203A |
Additional cDNA sequence: AF151022.1 AK098226.1 BC003035.1 BC009915.2 BC015471.1 15 DOTS entries: DT.95311583 DT.91856187 DT.111209 DT.99935555 DT.216491 DT.121473002 DT.121492282 DT.121473006 DT.95167991 DT.121492099 DT.121492190 DT.121492216 DT.121492281 DT.40132482 DT.91992380 24/122 AceView cDNA sequences (see all 122): BQ233213 AW452994 BM742540 BC003035 BM770543 BX342185 BM756948 AW188332 BQ059867 BM848508 BC015471 BQ438887 BQ949331 BQ053012 BM826219 BC009915 BQ026895 BM767308 BP346676 BU150029 BM741389 BE675360 BM770758 BQ060913
GeneLoc Exon Structure
|
Expression
for FAM203A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM203A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM203A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM203A
SOURCE GeneReport for Unigene cluster: Hs.300224
SABiosciences Custom PCR Arrays for FAM203A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM203A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM203A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM203A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM203A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM203A |
Orthologs
for FAM203A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM203A gene from 8/33 species (see all 33) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
51(a) |
1 → many |
GL343744.1(153776-156467) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.227402 |
Xenopus laevis transcribed sequence with weak similarity more |
71.75(n) |
|
BJ045495.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.167932 |
Transcribed sequence with weak similarity to protein more |
73.03(n) |
|
BI983142.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG60731 |
CG6073 |
48.57(n)
37.69(a) |
|
43180 NM_143211.3 NP_651468.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y54H5A.26 |
Protein Y54H5A.2 |
21(a) |
1 → many |
III(5137283-5149543) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
HGH11 |
Hgh1p |
40.56(n)
31.86(a) |
|
853099 NP_011703.3 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G143001 |
armadillo/beta-catenin-like repeats-containing protein |
42.59(n)
30.6(a) |
|
837991 NM_101296.4 NP_172882.1 |
rice
(Oryza sativa) |
Liliopsida |
Os10g04068001 |
hypothetical protein |
43.92(n)
30.48(a) |
|
4348588 NM_001071101.1 NP_001064566.1 |
ENSEMBL Gene Tree for FAM203A (if available)
TreeFam Gene Tree for FAM203A (if available) |
Paralogs
for FAM203A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM203A gene
- FAM203B1 2
2 SIMAP similar genes for FAM203A using alignment to 2 protein entries: F203A_HUMAN (see all proteins):FAM203B C8orf30A
FAM203A for paralogs About GeneDecksing
|
Genomic Variants
for FAM203A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM203A (145192672 - 145195746 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM203A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM203A |
|
Disorders
/ Diseases
for FAM203A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM203A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM203A gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with FAM203A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
- A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM203A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM203A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM203A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM203A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM203A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM203A gene:
Search GeneIP for patents involving FAM203A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM203A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM203A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM203A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM203A | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM203A | | OriGene 3'-UTR Clone for FAM203A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM203A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM203A | | OriGene Custom Protein Services for FAM203A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM203A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM203A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM203A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM203A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM203A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM203A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM203A |
| |  |  |  |  | | | | |
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 | | | FAM203A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM203A |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM203A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM203A |
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