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Aliases for FAM200B Gene

Aliases for FAM200B Gene

  • Family With Sequence Similarity 200, Member B 2 3
  • Chromosome 4 Open Reading Frame 53 2
  • C4orf53 4

External Ids for FAM200B Gene

Previous GeneCards Identifiers for FAM200B Gene

  • GC04P015033

Summaries for FAM200B Gene

GeneCards Summary for FAM200B Gene

FAM200B (Family With Sequence Similarity 200, Member B) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is ZBED5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM200B Gene

Genomics for FAM200B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM200B Gene

Start:
15,681,662 bp from pter
End:
15,705,565 bp from pter
Size:
23,904 bases
Orientation:
Plus strand

Genomic View for FAM200B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM200B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM200B Gene

No data available for Regulatory Elements for FAM200B Gene

Proteins for FAM200B Gene

  • Protein details for FAM200B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CF97-F200B_HUMAN
    Recommended name:
    Putative protein FAM200B
    Protein Accession:
    P0CF97
    Secondary Accessions:

    Protein attributes for FAM200B Gene

    Size:
    657 amino acids
    Molecular mass:
    76034 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM200B Gene

Proteomics data for FAM200B Gene at MOPED

Post-translational modifications for FAM200B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM200B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM200B Gene

Domains for FAM200B Gene

Protein Domains for FAM200B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM200B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CF97

UniProtKB/Swiss-Prot:

F200B_HUMAN :
  • P0CF97
Family:
  • Belongs to the FAM200 family.
genes like me logo Genes that share domains with FAM200B: view

No data available for Gene Families for FAM200B Gene

Function for FAM200B Gene

Gene Ontology (GO) - Molecular Function for FAM200B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with FAM200B: view

Phenotypes for FAM200B Gene

genes like me logo Genes that share phenotypes with FAM200B: view

Animal Model Products

CRISPR Products

miRNA for FAM200B Gene

miRTarBase miRNAs that target FAM200B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM200B Gene

Localization for FAM200B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM200B Gene COMPARTMENTS Subcellular localization image for FAM200B gene
Compartment Confidence
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for FAM200B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
genes like me logo Genes that share ontologies with FAM200B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM200B Gene

Pathways for FAM200B Gene

SuperPathways for FAM200B Gene

No Data Available

Interacting Proteins for FAM200B Gene

Gene Ontology (GO) - Biological Process for FAM200B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006355 regulation of transcription, DNA-templated --
genes like me logo Genes that share ontologies with FAM200B: view

No data available for Pathways by source for FAM200B Gene

Transcripts for FAM200B Gene

mRNA/cDNA for FAM200B Gene

Unigene Clusters for FAM200B Gene

Family with sequence similarity 200, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM200B

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM200B
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM200B Gene

No ASD Table

Relevant External Links for FAM200B Gene

GeneLoc Exon Structure for
FAM200B
ECgene alternative splicing isoforms for
FAM200B

Expression for FAM200B Gene

mRNA expression in normal human tissues for FAM200B Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM200B Gene

SOURCE GeneReport for Unigene cluster for FAM200B Gene Hs.399980

genes like me logo Genes that share expressions with FAM200B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM200B Gene

Orthologs for FAM200B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM200B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM200B 35
  • 99.64 (n)
  • 99.39 (a)
cow
(Bos Taurus)
Mammalia FAM200B 35
  • 86.78 (n)
  • 84.38 (a)
dog
(Canis familiaris)
Mammalia FAM200B 35
  • 92.54 (n)
  • 90.87 (a)
mouse
(Mus musculus)
Mammalia 2410018M08Rik 36
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 28 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii BX927234.1 36
  • 28 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
ManyToMany
Species with no ortholog for FAM200B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM200B Gene

ENSEMBL:
Gene Tree for FAM200B (if available)
TreeFam:
Gene Tree for FAM200B (if available)

Paralogs for FAM200B Gene

Paralogs for FAM200B Gene

Selected SIMAP similar genes for FAM200B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM200B: view

Variants for FAM200B Gene

Sequence variations from dbSNP and Humsavar for FAM200B Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
rs1053112 -- 15,687,058(+) GAATC(C/T)GGAAT synonymous-codon, reference
rs2302469 -- 15,686,981(-) ATGAT(C/G)CATTT missense, reference
rs4235380 -- 15,688,305(+) actga(A/G)tttaa missense, reference
rs6449160 -- 15,688,610(+) ttcga(A/C)accct missense, reference
rs6811179 -- 15,683,728(+) TAACA(A/T)TCCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM200B Gene

Variant ID Type Subtype PubMed ID
dgv1586e1 CNV Complex 17122850
dgv1587e1 CNV Complex 17122850
nsv428439 CNV Gain+Loss 18775914
dgv315n21 CNV Loss 19592680

Relevant External Links for FAM200B Gene

HapMap Linkage Disequilibrium report
FAM200B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM200B Gene

Disorders for FAM200B Gene

Relevant External Links for FAM200B

Genetic Association Database (GAD)
FAM200B
Human Genome Epidemiology (HuGE) Navigator
FAM200B
genes like me logo Genes that share disorders with FAM200B: view

No data available for UniProtKB/Swiss-Prot for FAM200B Gene

Publications for FAM200B Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3
  4. Genetic associations of variants in genes encoding HIV-dependency factors required for HIV-1 infection. (PMID: 21083371) Chinn L.W. … O'Brien S.J. (J. Infect. Dis. 2010) 48
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM200B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM200B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM200B
    • Block miRNA regulation of FAM200B using miScript Target Protectors

    Sources for FAM200B Gene

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