FAM200B Gene
protein-coding GIFtS: 36
GCID: GC04P015683
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family with sequence similarity 200, member B
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Aliases
for FAM200B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 200, Member B1 2 | | C4orf531 | | Putative Protein FAM200B2 |
Export aliases for FAM200B gene to outside databasesPrevious GC identifer: GC04P015033 |
Summaries
for FAM200B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM200B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_006316.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM200B
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM200B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM200B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4p15.32 Ensembl cytogenetic band: 4p15.32 HGNC cytogenetic band: 4p15.32FAM200B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P015683: view genomic region
(about GC identifiers)
Start:
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15,683,285 bp from pter |
End:
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15,707,188 bp from pter |
Size:
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23,904 bases |
Orientation:
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plus strand |
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Proteins
for FAM200B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F200B_HUMAN, P0CF97 (See
protein sequence)Recommended Name: Putative protein FAM200B Size: 657 amino acids; 76034 Da
Caution: Could be the product of a pseudogeneExplore the universe of human proteins at neXtProt for FAM200B: NX_P0CF97
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P0CF97
FAM200B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001138663.1
ENSEMBL proteins: ENSP00000422751 ENSP00000393017
Human Recombinant Protein Products:
FAM200B Antibody Products:
Assay Products for FAM200B: |
Protein
Domains /
Families
for FAM200B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM200B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P0CF97ProtoNet protein and cluster: P0CF97 UniProtKB/Swiss-Prot: F200B_HUMAN, P0CF97Similarity: Belongs to the FAM200 family |
Function
for FAM200B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM200B (NM_001145191) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM200B | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM200B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM200B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- |
FAM200B for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for FAM200B:
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Pathways & Interactions
for FAM200B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM200B
|
Drugs & Compounds
for FAM200B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM200B
Search CenterWatch for drugs/clinical trials and news about FAM200B / F200B
|
Transcripts
for FAM200B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM200B gene: NM_001145191.1 Unigene Clusters for FAM200B: Family with sequence similarity 200, member B Hs.399980 [show with all ESTs], Hs.731718 [show with all ESTs]Unigene Representative Sequences: BC017971, NM_00114519118/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000510920 ENST00000504823 ENST00000504137(uc003gog.3) ENST00000515697
ENST00000509022 ENST00000510032 ENST00000512855 ENST00000515430 ENST00000505260
ENST00000504598 ENST00000502502 ENST00000503617 ENST00000507305 ENST00000507992
ENST00000513053 ENST00000422728(uc003gof.4) ENST00000514803 ENST00000508567
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM200B (NM_001145191) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM200B | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM200B |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM200B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM200B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM200B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM200B |
Additional cDNA sequence: AK124651.1 BC035074.1 BC048993.1 19 DOTS entries: DT.113905 DT.308789 DT.121249068 DT.100793873 DT.97842052 DT.95325491 DT.91728342 DT.97770696 DT.100793868 DT.95267960 DT.100793867 DT.100793874 DT.100793869 DT.100793870 DT.121248909 DT.121248990 DT.121249052 DT.121249125 DT.100746236 24/156 AceView cDNA sequences (see all 156): AW439843 BX952106 AI291426 BM830033 AW162222 AI338822 AA782797 AI350281 BF431404 AI148237 AI379274 AI572104 BM671074 AA701441 AI350642 BQ004196 BQ424817 BF740265 BM709810 AA700799 AI802100 BM701922 AI306587 BX952094
GeneLoc Exon Structure
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Expression
for FAM200B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM200B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAATCAATTC
About this image
See FAM200B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM200B
SOURCE GeneReport for Unigene clusters: Hs.399980 Hs.731718
SABiosciences Custom PCR Arrays for FAM200B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM200B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM200B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM200B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM200B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM200B |
Orthologs
for FAM200B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM200B gene from 2/5 species (see all 5) About this table
ENSEMBL Gene Tree for FAM200B (if available)
TreeFam Gene Tree for FAM200B (if available) |
Paralogs
for FAM200B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM200B gene
- ZBED52 KRBA22 C5orf542 SCAND32 GTF2IRD22 FAM200A2 GTF2IRD2B2 EPM2AIP12
3 SIMAP similar genes for FAM200B using alignment to 2 protein entries: F200B_HUMAN (see all proteins):FAM200A C5orf54 ZBED5
FAM200B for paralogs About GeneDecksing
|
Genomic Variants
for FAM200B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM200B |
|
Disorders
/ Diseases
for FAM200B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM200B for disorders About MalaCards
FAM200B for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: FAM200B (1 document)
Export disorders for FAM200B gene to outside databases
|
Publications
for FAM200B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM200B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM200B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
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External Searches for FAM200B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM200B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM200B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM200B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM200B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM200B gene:
Search GeneIP for patents involving FAM200B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM200B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM200B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM200B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM200B | | | OriGene Protein Over-expression Lysate for FAM200B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM200B | | OriGene 3'-UTR Clone for FAM200B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM200B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM200B | | OriGene Custom Protein Services for FAM200B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM200B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM200B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM200B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM200B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM200B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM200B |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM200B |
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 | | | FAM200B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM200B |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM200B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM200B |
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