Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM200A Gene

Aliases for FAM200A Gene

  • Family With Sequence Similarity 200 Member A 2 3 5
  • C7orf38 3 4
  • Family With Sequence Similarity 200, Member A 2
  • Chromosome 7 Open Reading Frame 38 2
  • Protein FAM200A 3

External Ids for FAM200A Gene

Previous HGNC Symbols for FAM200A Gene

  • C7orf38

Previous GeneCards Identifiers for FAM200A Gene

  • GC07M099143
  • GC07M093780

Summaries for FAM200A Gene

Entrez Gene Summary for FAM200A Gene

  • This gene encodes a protein of unknown function. The protein is weakly similar to transposase-like proteins in human and mouse. [provided by RefSeq, Jul 2008]

GeneCards Summary for FAM200A Gene

FAM200A (Family With Sequence Similarity 200 Member A) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is FAM200B.

Gene Wiki entry for FAM200A Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM200A Gene

Genomics for FAM200A Gene

Regulatory Elements for FAM200A Gene

Enhancers for FAM200A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F099616 0.4 ENCODE 10.4 -58.9 -58874 4.5 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 CBX5 ZSCAN25 LOC100131859 TRRAP ZNF655 LOC100419643 STAG3L5P ENSG00000242798 LOC101927550 PPP1R35 PCOLCE
GH07F099839 0.6 ENCODE 10.3 -281.3 -281251 2.4 HDGF PKNOX1 MLX ARNT CREB3L1 ARID4B SIN3A DMAP1 YY1 ZNF766 ZSCAN25 LOC100419643 SMURF1 PCOLCE LOC100131859 TRRAP EPHB4 AP4M1 MBLAC1 PPP1R35
GH07F099994 0.4 Ensembl 10.3 -435.1 -435089 0.6 CTCF ATF1 SAP130 MAX ZNF384 ZNF2 RAD21 ZNF324 ZNF664 ZNF143 LOC100131859 ZSCAN21 COPS6 TRIM4 GJC3 ENSG00000237640 CNPY4 MBLAC1 ZKSCAN5 FAM200A
GH07F100019 0.6 ENCODE 10.3 -460.3 -460258 1.3 HDGF PKNOX1 ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 MBLAC1 LOC100131859 MIR6875 EPHB4 PCOLCE COPS6 ZSCAN21 PVRIG CNPY4 ZKSCAN5
GH07F100263 0.4 ENCODE 10.2 -705.6 -705600 2.2 PKNOX1 INSM2 KLF17 FEZF1 ZNF2 ZNF121 GLIS2 ZNF366 SCRT2 KLF7 PILRA PVRIG LOC100131859 COPS6 STAG3 GPC2 GAL3ST4 C7orf43 MIR4658 LAMTOR4
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM200A on UCSC Golden Path with GeneCards custom track

Promoters for FAM200A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000068015 595 2801 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for FAM200A Gene

Chromosome:
7
Start:
99,546,300 bp from pter
End:
99,559,395 bp from pter
Size:
13,096 bases
Orientation:
Minus strand

Genomic View for FAM200A Gene

Genes around FAM200A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM200A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM200A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM200A Gene

Proteins for FAM200A Gene

  • Protein details for FAM200A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TCP9-F200A_HUMAN
    Recommended name:
    Protein FAM200A
    Protein Accession:
    Q8TCP9
    Secondary Accessions:
    • A4D293
    • A8K3V9
    • B2RD92
    • C9J6A8
    • D6W5T2
    • Q8N9P3

    Protein attributes for FAM200A Gene

    Size:
    573 amino acids
    Molecular mass:
    66276 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM200A Gene

Post-translational modifications for FAM200A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM200A Gene

Antibody Products

  • Abcam antibodies for FAM200A
  • Santa Cruz Biotechnology (SCBT) Antibodies for FAM200A

No data available for DME Specific Peptides for FAM200A Gene

Domains & Families for FAM200A Gene

Protein Domains for FAM200A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM200A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TCP9

UniProtKB/Swiss-Prot:

F200A_HUMAN :
  • Belongs to the FAM200 family.
Family:
  • Belongs to the FAM200 family.
genes like me logo Genes that share domains with FAM200A: view

No data available for Gene Families for FAM200A Gene

Function for FAM200A Gene

Gene Ontology (GO) - Molecular Function for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA --
GO:0003676 nucleic acid binding IEA --
GO:0003677 DNA binding IBA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM200A: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM200A Gene

Localization for FAM200A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM200A Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM200A Gene COMPARTMENTS Subcellular localization image for FAM200A gene
Compartment Confidence
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005654 nucleoplasm IBA --
GO:0005737 cytoplasm IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM200A: view

Pathways & Interactions for FAM200A Gene

SuperPathways for FAM200A Gene

No Data Available

Interacting Proteins for FAM200A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000411372%0d%0a9606.ENSP00000253363%0d%0a
Selected Interacting proteins: ENSP00000411372 Q8TCP9-F200A_HUMAN for FAM200A Gene via STRING UniProtKB IID

Gene Ontology (GO) - Biological Process for FAM200A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
genes like me logo Genes that share ontologies with FAM200A: view

No data available for Pathways by source and SIGNOR curated interactions for FAM200A Gene

Transcripts for FAM200A Gene

mRNA/cDNA for FAM200A Gene

Unigene Clusters for FAM200A Gene

Family with sequence similarity 200, member A:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM200A Gene

No ASD Table

Relevant External Links for FAM200A Gene

GeneLoc Exon Structure for
FAM200A
ECgene alternative splicing isoforms for
FAM200A

Expression for FAM200A Gene

mRNA expression in normal human tissues for FAM200A Gene

Protein differential expression in normal tissues from HIPED for FAM200A Gene

This gene is overexpressed in Platelet (28.7), Fetal testis (18.1), Fetal heart (14.8), and Liver (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM200A Gene



Protein tissue co-expression partners for FAM200A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM200A Gene:

FAM200A

SOURCE GeneReport for Unigene cluster for FAM200A Gene:

Hs.596587
genes like me logo Genes that share expression patterns with FAM200A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM200A Gene

Orthologs for FAM200A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM200A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM200A 34 35
  • 99.36 (n)
dog
(Canis familiaris)
Mammalia FAM200A 34 35
  • 89.71 (n)
cow
(Bos Taurus)
Mammalia FAM200A 34
  • 88.37 (n)
mouse
(Mus musculus)
Mammalia 2410018M08Rik 35
  • 25 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 24 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii CR388095.1 35
  • 31 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 22 (a)
ManyToMany
Species where no ortholog for FAM200A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM200A Gene

ENSEMBL:
Gene Tree for FAM200A (if available)
TreeFam:
Gene Tree for FAM200A (if available)

Paralogs for FAM200A Gene

Paralogs for FAM200A Gene

(5) SIMAP similar genes for FAM200A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM200A: view

Variants for FAM200A Gene

Sequence variations from dbSNP and Humsavar for FAM200A Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs10238965 -- 99,548,222(+) GATGA(C/T)AATAA reference, synonymous-codon
rs112968656 -- 99,553,031(+) TACAT(C/G)TATAT intron-variant, upstream-variant-2KB
rs113407004 -- 99,547,746(+) TGCTG(G/T)GTTTT reference, missense
rs113489769 -- 99,548,913(+) TCGCT(A/C)TTGTT intron-variant
rs114437353 -- 99,550,786(+) AAAAC(C/T)CTTCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM200A Gene

Variant ID Type Subtype PubMed ID
esv2507396 CNV insertion 19546169
nsv1117743 CNV deletion 24896259

Variation tolerance for FAM200A Gene

Gene Damage Index Score: 2.55; 44.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM200A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM200A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM200A Gene

Disorders for FAM200A Gene

Relevant External Links for FAM200A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM200A

No disorders were found for FAM200A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM200A Gene

Publications for FAM200A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3 4 64
  4. Interspersed repeats and other mementos of transposable elements in mammalian genomes. (PMID: 10607616) Smit A.F.A. (Curr. Opin. Genet. Dev. 1999) 2 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for FAM200A Gene

Sources for FAM200A Gene

Content
Loading form....