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Aliases for FAM196B Gene

Aliases for FAM196B Gene

  • Family With Sequence Similarity 196, Member B 2 3
  • C5orf57 3 4
  • Chromosome 5 Open Reading Frame 57 2
  • Protein FAM196B 3

External Ids for FAM196B Gene

Previous HGNC Symbols for FAM196B Gene

  • C5orf57

Previous GeneCards Identifiers for FAM196B Gene

  • GC05M169225
  • GC05M164388

Summaries for FAM196B Gene

GeneCards Summary for FAM196B Gene

FAM196B (Family With Sequence Similarity 196, Member B) is a Protein Coding gene. An important paralog of this gene is FAM196A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM196B Gene

Genomics for FAM196B Gene

Genomic Location for FAM196B Gene

Start:
169,863,715 bp from pter
End:
169,980,740 bp from pter
Size:
117,026 bases
Orientation:
Minus strand

Genomic View for FAM196B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM196B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM196B Gene

No data available for Regulatory Elements for FAM196B Gene

Proteins for FAM196B Gene

  • Protein details for FAM196B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NMK8-F196B_HUMAN
    Recommended name:
    Protein FAM196B
    Protein Accession:
    A6NMK8
    Secondary Accessions:

    Protein attributes for FAM196B Gene

    Size:
    535 amino acids
    Molecular mass:
    59204 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM196B Gene

Proteomics data for FAM196B Gene at MOPED

Post-translational modifications for FAM196B Gene

No Post-translational modifications

Other Protein References for FAM196B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM196B Gene

Domains for FAM196B Gene

Protein Domains for FAM196B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM196B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A6NMK8

UniProtKB/Swiss-Prot:

F196B_HUMAN :
  • A6NMK8
Family:
  • Belongs to the FAM196 family.
genes like me logo Genes that share domains with FAM196B: view

No data available for Gene Families for FAM196B Gene

Function for FAM196B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM196B Gene

Localization for FAM196B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM196B Gene COMPARTMENTS Subcellular localization image for FAM196B gene
Compartment Confidence
nucleus 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM196B Gene

Pathways for FAM196B Gene

SuperPathways for FAM196B Gene

No Data Available

Interacting Proteins for FAM196B Gene

Gene Ontology (GO) - Biological Process for FAM196B Gene

None

No data available for Pathways by source for FAM196B Gene

Transcripts for FAM196B Gene

mRNA/cDNA for FAM196B Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM196B Gene

Family with sequence similarity 196, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM196B Gene

No ASD Table

Relevant External Links for FAM196B Gene

GeneLoc Exon Structure for
FAM196B
ECgene alternative splicing isoforms for
FAM196B

Expression for FAM196B Gene

mRNA expression in normal human tissues for FAM196B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM196B Gene

SOURCE GeneReport for Unigene cluster for FAM196B Gene Hs.721917

genes like me logo Genes that share expressions with FAM196B: view

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM196B Gene

Orthologs for FAM196B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM196B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM196B 35
  • 99.19 (n)
  • 99.07 (a)
FAM196B 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM196B 35
  • 85.3 (n)
  • 84.43 (a)
FAM196B 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM196B 35
  • 88.16 (n)
  • 84.67 (a)
FAM196B 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam196b 35
  • 82.06 (n)
  • 77.94 (a)
Fam196b 16
Fam196b 36
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM196B 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM196B 36
  • 60 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam196b 35
  • 81.18 (n)
  • 77.3 (a)
chicken
(Gallus gallus)
Aves FAM196B 35
  • 58.27 (n)
  • 51.36 (a)
FAM196B 36
  • 43 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM196B 36
  • 47 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101734510 35
  • 71.68 (n)
  • 69.89 (a)
zebrafish
(Danio rerio)
Actinopterygii FAM196B 36
  • 17 (a)
OneToOne
Species with no ortholog for FAM196B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM196B Gene

ENSEMBL:
Gene Tree for FAM196B (if available)
TreeFam:
Gene Tree for FAM196B (if available)

Paralogs for FAM196B Gene

Paralogs for FAM196B Gene

genes like me logo Genes that share paralogs with FAM196B: view

Variants for FAM196B Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM196B Gene

Variant ID Type Subtype PubMed ID
esv988430 CNV Insertion 20482838
nsv328128 CNV Loss 16902084
esv2731060 CNV Deletion 23290073

Relevant External Links for FAM196B Gene

HapMap Linkage Disequilibrium report
FAM196B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for FAM196B Gene

Disorders for FAM196B Gene

Relevant External Links for FAM196B

Genetic Association Database (GAD)
FAM196B
Human Genome Epidemiology (HuGE) Navigator
FAM196B
genes like me logo Genes that share disorders with FAM196B: view

No data available for UniProtKB/Swiss-Prot for FAM196B Gene

Publications for FAM196B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  4. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris. (PMID: 24927181) Navarini A.A. … Barker J.N. (Nat Commun 2014) 3
  5. A second-generation genomewide screen for asthma-susceptibility alleles in a founder population. (PMID: 11022011) Ober C. … Cox N.J. (Am. J. Hum. Genet. 2000) 48

Products for FAM196B Gene

Sources for FAM196B Gene

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