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Aliases for FAM195B Gene

Aliases for FAM195B Gene

  • Family With Sequence Similarity 195, Member B 2 3

External Ids for FAM195B Gene

Previous GeneCards Identifiers for FAM195B Gene

  • GC17M079783
  • GC17M075181

Summaries for FAM195B Gene

GeneCards Summary for FAM195B Gene

FAM195B (Family With Sequence Similarity 195, Member B) is a Protein Coding gene. An important paralog of this gene is FAM195A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM195B Gene

Genomics for FAM195B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM195B Gene

81,822,361 bp from pter
81,833,302 bp from pter
10,942 bases
Minus strand

Genomic View for FAM195B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM195B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM195B Gene

No data available for Regulatory Elements for FAM195B Gene

Proteins for FAM195B Gene

  • Protein details for FAM195B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM195B
    Protein Accession:
    Secondary Accessions:
    • Q6ZUL0

    Protein attributes for FAM195B Gene

    97 amino acids
    Molecular mass:
    10920 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86211.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

neXtProt entry for FAM195B Gene

Proteomics data for FAM195B Gene at MOPED

Post-translational modifications for FAM195B Gene

  • Ubiquitination at Lys76
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FAM195B Gene

Domains for FAM195B Gene

Protein Domains for FAM195B Gene


Suggested Antigen Peptide Sequences for FAM195B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • C9JLW8
  • Belongs to the FAM195 family.
genes like me logo Genes that share domains with FAM195B: view

No data available for Gene Families for FAM195B Gene

Function for FAM195B Gene

Phenotypes for FAM195B Gene

GenomeRNAi human phenotypes for FAM195B:
genes like me logo Genes that share phenotypes with FAM195B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM195B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM195B Gene

Localization for FAM195B Gene

Subcellular locations from

Jensen Localization Image for FAM195B Gene COMPARTMENTS Subcellular localization image for FAM195B gene
Compartment Confidence
mitochondrion 2
nucleus 2
cytosol 1
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM195B Gene

Pathways for FAM195B Gene

SuperPathways for FAM195B Gene

No Data Available

Interacting Proteins for FAM195B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000409009 C9JLW8-F195B_HUMAN for FAM195B Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM195B Gene


No data available for Pathways by source for FAM195B Gene

Transcripts for FAM195B Gene

Unigene Clusters for FAM195B Gene

Family with sequence similarity 195, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM195B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM195B Gene

No ASD Table

Relevant External Links for FAM195B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM195B Gene

mRNA expression in normal human tissues for FAM195B Gene

Protein differential expression in normal tissues for FAM195B Gene

This gene is overexpressed in Fetal Brain (17.4), Fetal ovary (9.1), and Peripheral blood mononuclear cells (6.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM195B Gene

SOURCE GeneReport for Unigene cluster for FAM195B Gene Hs.514632

genes like me logo Genes that share expressions with FAM195B: view

Expression partners for FAM195B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM195B Gene

Orthologs for FAM195B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM195B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM195B 35
  • 91.41 (n)
  • 90.72 (a)
FAM195B 36
  • 93 (a)
(Canis familiaris)
Mammalia FAM195B 35
  • 88.89 (n)
  • 85.96 (a)
FAM195B 36
  • 91 (a)
(Mus musculus)
Mammalia Fam195b 35
  • 88.66 (n)
  • 90.72 (a)
Fam195b 16
Fam195b 36
  • 91 (a)
(Pan troglodytes)
Mammalia FAM195B 35
  • 99.72 (n)
  • 100 (a)
FAM195B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam195b 35
  • 87.29 (n)
  • 90.72 (a)
(Monodelphis domestica)
Mammalia FAM195B 36
  • 37 (a)
(Gallus gallus)
Aves FAM195B 35
  • 81.56 (n)
  • 85.11 (a)
(Anolis carolinensis)
Reptilia FAM195B 36
  • 89 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam195b 35
  • 70.1 (n)
  • 78.35 (a)
Str.12007 35
(Danio rerio)
Actinopterygii fam195b 35
  • 63.51 (n)
  • 60 (a)
fam195b 36
  • 58 (a)
Species with no ortholog for FAM195B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM195B Gene

Gene Tree for FAM195B (if available)
Gene Tree for FAM195B (if available)

Paralogs for FAM195B Gene

Paralogs for FAM195B Gene

Selected SIMAP similar genes for FAM195B Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with FAM195B: view

Variants for FAM195B Gene

Sequence variations from dbSNP and Humsavar for FAM195B Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1047441 -- 81,822,805(-) GCCCC(A/C)CCCCA utr-variant-3-prime
rs1047559 -- 81,822,531(-) TGGCT(C/T)TGGGG utr-variant-3-prime
rs1047580 -- 81,822,467(-) AGTGT(C/T)TGTGT utr-variant-3-prime
rs3187588 -- 81,822,482(-) GCCCT(C/T)TGAAA utr-variant-3-prime
rs4013609 -- 81,826,522(-) TTTTT(-/TT)GACAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM195B Gene

Variant ID Type Subtype PubMed ID
nsv909052 CNV Loss 21882294
nsv428351 CNV Gain 18775914
dgv3330n71 CNV Loss 21882294
dgv3332n71 CNV Loss 21882294
nsv470620 CNV Loss 18288195
dgv3333n71 CNV Loss 21882294
nsv909134 CNV Loss 21882294
esv21913 CNV Gain+Loss 19812545
nsv909128 CNV Gain+Loss 21882294

Relevant External Links for FAM195B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM195B Gene

Disorders for FAM195B Gene

No disorders were found for FAM195B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM195B Gene

Publications for FAM195B Gene

  1. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 3
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PMID: 21890473) Wagner S.A. … Choudhary C. (Mol. Cell Proteomics 2011) 3
  5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PMID: 23000965) Povlsen L.K. … Choudhary C. (Nat. Cell Biol. 2012) 3

Products for FAM195B Gene

Sources for FAM195B Gene

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