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Aliases for FAM193A Gene

Aliases for FAM193A Gene

  • Family With Sequence Similarity 193, Member A 2 3
  • C4orf8 3 4
  • Chromosome 4 Open Reading Frame 8 2
  • Protein IT14 4
  • RES4-22 3

External Ids for FAM193A Gene

Previous HGNC Symbols for FAM193A Gene

  • C4orf8

Previous GeneCards Identifiers for FAM193A Gene

  • GC04P002596

Summaries for FAM193A Gene

GeneCards Summary for FAM193A Gene

FAM193A (Family With Sequence Similarity 193, Member A) is a Protein Coding gene. An important paralog of this gene is FAM193B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM193A Gene

Genomics for FAM193A Gene

Genomic Location for FAM193A Gene

2,596,288 bp from pter
2,732,575 bp from pter
136,288 bases
Plus strand

Genomic View for FAM193A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM193A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM193A Gene

No data available for Regulatory Elements for FAM193A Gene

Proteins for FAM193A Gene

  • Protein details for FAM193A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM193A
    Protein Accession:
    Secondary Accessions:
    • B7ZM85
    • B9EGR0
    • E9PFA1
    • O43607
    • P78311
    • P78313
    • Q9UEG8

    Protein attributes for FAM193A Gene

    1265 amino acids
    Molecular mass:
    139988 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM193A Gene

neXtProt entry for FAM193A Gene

Proteomics data for FAM193A Gene at MOPED

Post-translational modifications for FAM193A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM193A Gene

Domains & Families for FAM193A Gene

Protein Domains for FAM193A Gene


Suggested Antigen Peptide Sequences for FAM193A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM193 family.
  • Belongs to the FAM193 family.
genes like me logo Genes that share domains with FAM193A: view

No data available for Gene Families for FAM193A Gene

Function for FAM193A Gene

genes like me logo Genes that share phenotypes with FAM193A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM193A Gene

Localization for FAM193A Gene

Subcellular locations from

Jensen Localization Image for FAM193A Gene COMPARTMENTS Subcellular localization image for FAM193A gene
Compartment Confidence
cytosol 2
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM193A Gene

Pathways & Interactions for FAM193A Gene

SuperPathways for FAM193A Gene

No Data Available

Interacting Proteins for FAM193A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: P78312-F193A_HUMAN ENSP00000372290 for FAM193A Gene via I2D STRING

Gene Ontology (GO) - Biological Process for FAM193A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM193A Gene

Drugs & Compounds for FAM193A Gene

No Compound Related Data Available

Transcripts for FAM193A Gene

Unigene Clusters for FAM193A Gene

Family with sequence similarity 193, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM193A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM193A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21 ^
SP1: - - - -
SP2: - - -
SP3: - - - - -
SP5: -
SP6: -
SP7: - - -

ExUns: 22 ^ 23 ^ 24
SP1: -
SP2: -
SP3: -

Relevant External Links for FAM193A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM193A Gene

mRNA expression in normal human tissues for FAM193A Gene

Protein differential expression in normal tissues from HIPED for FAM193A Gene

This gene is overexpressed in Heart (55.6) and Placenta (12.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM193A Gene

SOURCE GeneReport for Unigene cluster for FAM193A Gene Hs.652364

genes like me logo Genes that share expression patterns with FAM193A: view

Protein tissue co-expression partners for FAM193A Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM193A Gene

Orthologs for FAM193A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM193A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM193A 35
  • 81.45 (n)
  • 83.63 (a)
FAM193A 36
  • 82 (a)
(Canis familiaris)
Mammalia FAM193A 35
  • 87.02 (n)
  • 89.81 (a)
FAM193A 36
  • 77 (a)
(Mus musculus)
Mammalia Fam193a 35
  • 86.22 (n)
  • 89.09 (a)
Fam193a 16
Fam193a 36
  • 72 (a)
(Pan troglodytes)
Mammalia FAM193A 35
  • 99.18 (n)
  • 98.97 (a)
FAM193A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam193a 35
  • 82.82 (n)
  • 84.88 (a)
(Monodelphis domestica)
Mammalia FAM193A 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia FAM193A 36
  • 70 (a)
(Gallus gallus)
Aves FAM193A 35
  • 76.11 (n)
  • 79.93 (a)
FAM193A 36
  • 70 (a)
(Anolis carolinensis)
Reptilia FAM193A 36
  • 53 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam193a 35
  • 71.32 (n)
  • 72.85 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.3384 35
(Danio rerio)
Actinopterygii Dr.11568 35
LOC100534836 35
  • 68.68 (n)
  • 68.79 (a)
fam193a 36
  • 46 (a)
Species with no ortholog for FAM193A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM193A Gene

Gene Tree for FAM193A (if available)
Gene Tree for FAM193A (if available)

Paralogs for FAM193A Gene

Paralogs for FAM193A Gene

(2) SIMAP similar genes for FAM193A Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM193A: view

Variants for FAM193A Gene

Sequence variations from dbSNP and Humsavar for FAM193A Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_022863 -
VAR_056783 -

Structural Variations from Database of Genomic Variants (DGV) for FAM193A Gene

Variant ID Type Subtype PubMed ID
esv2726835 CNV Deletion 23290073
nsv878443 CNV Gain 21882294
nsv829839 CNV Loss 17160897
esv2726856 CNV Deletion 23290073
esv2678225 CNV Deletion 23128226
esv275488 CNV Loss 21479260
nsv470001 CNV Gain 18288195
nsv878444 CNV Loss 21882294
nsv470002 CNV Loss 18288195
dgv5426n71 CNV Loss 21882294
nsv516797 CNV Loss 19592680

Variation tolerance for FAM193A Gene

Residual Variation Intolerance Score: 16.29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.29; 70.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM193A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM193A Gene

Disorders for FAM193A Gene

Relevant External Links for FAM193A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM193A: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM193A Gene

Publications for FAM193A Gene

  1. The primary structure and genomic organization of five novel transcripts located close to the Huntington's disease gene on human chromosome 4p16.3. (PMID: 9734812) Hadano S. … Ikeda J.-E. (DNA Res. 1998) 2 67
  2. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PMID: 24255178) Couzens A.L. … Gingras A.C. (Sci Signal 2013) 67
  3. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PMID: 21406692) Rigbolt K.T. … Blagoev B. (Sci. Signal. 2011) 67
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 67
  5. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PMID: 19413330) Gauci S. … Mohammed S. (Anal. Chem. 2009) 67

Products for FAM193A Gene

Sources for FAM193A Gene

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