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Aliases for FAM192A Gene

Aliases for FAM192A Gene

  • Family With Sequence Similarity 192 Member A 2 3 5
  • NEFA-Interacting Nuclear Protein NIP30 3 4
  • C16orf94 3 4
  • NIP30 3 4
  • Family With Sequence Similarity 192, Member A 2
  • NEFA Interacting Nuclear Protein NIP30 2
  • Chromosome 16 Open Reading Frame 94 2
  • Protein FAM192A 3
  • CDA018 3
  • CDA10 3

External Ids for FAM192A Gene

Previous HGNC Symbols for FAM192A Gene

  • C16orf94

Previous GeneCards Identifiers for FAM192A Gene

  • GC16M055744
  • GC16M043056

Summaries for FAM192A Gene

GeneCards Summary for FAM192A Gene

FAM192A (Family With Sequence Similarity 192 Member A) is a Protein Coding gene.

Gene Wiki entry for FAM192A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM192A Gene

Genomics for FAM192A Gene

Regulatory Elements for FAM192A Gene

Enhancers for FAM192A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G057141 1.4 Ensembl ENCODE dbSUPER 27.3 +42.5 42477 5.1 HDAC1 ELF3 PKNOX1 FOXA2 RAD21 ZNF335 TCF12 ZNF121 GATA2 EGR1 FAM192A PLLP RSPRY1 ARL2BP BBS2 ENSG00000279803 ENSG00000279019
GH16G057261 2 FANTOM5 Ensembl ENCODE dbSUPER 18.9 -81.1 -81130 10.8 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 NFYC TBX21 PLLP FAM192A POLR2C ENSG00000272372 LOC101927556 ENSG00000260038
GH16G057146 1.2 Ensembl ENCODE dbSUPER 31 +38.2 38207 3.5 CTCF STAT1 MAX ZIC2 ZNF491 NR2F2 ETS1 ZNF121 SCRT2 ZBTB33 FAM192A PLLP CPNE2 RSPRY1 ENSG00000261114 ENSG00000279019
GH16G057132 1.3 Ensembl ENCODE dbSUPER 24.6 +51.9 51911 4.6 CTCF PKNOX1 PLRG1 EBF1 RAD21 ZNF316 ZNF366 ZNF143 SMC3 IKZF2 FAM192A NUDT21 CPNE2 RSPRY1 PLLP LOC105371289 GC16P057096
GH16G057184 1.4 ENCODE dbSUPER 21.4 -0.6 -584 4.6 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 FAM192A PLLP RSPRY1 NUDT21 NUP93 ARL2BP
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM192A on UCSC Golden Path with GeneCards custom track

Promoters for FAM192A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000086390 -270 3001 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207

Genomic Location for FAM192A Gene

Chromosome:
16
Start:
57,152,466 bp from pter
End:
57,186,230 bp from pter
Size:
33,765 bases
Orientation:
Minus strand

Genomic View for FAM192A Gene

Genes around FAM192A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM192A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM192A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM192A Gene

Proteins for FAM192A Gene

  • Protein details for FAM192A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9GZU8-F192A_HUMAN
    Recommended name:
    Protein FAM192A
    Protein Accession:
    Q9GZU8

    Protein attributes for FAM192A Gene

    Size:
    254 amino acids
    Molecular mass:
    28912 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM192A Gene

Post-translational modifications for FAM192A Gene

  • Ubiquitination at Lys151
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FAM192A Gene

Domains & Families for FAM192A Gene

Protein Domains for FAM192A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM192A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FAM192A: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FAM192A Gene

Function for FAM192A Gene

Gene Ontology (GO) - Molecular Function for FAM192A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM192A: view
genes like me logo Genes that share phenotypes with FAM192A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM192A Gene

Localization for FAM192A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM192A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM192A gene
Compartment Confidence
nucleus 5
cytosol 1

Gene Ontology (GO) - Cellular Components for FAM192A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with FAM192A: view

Pathways & Interactions for FAM192A Gene

SuperPathways for FAM192A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM192A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM192A Gene

Drugs & Compounds for FAM192A Gene

No Compound Related Data Available

Transcripts for FAM192A Gene

Unigene Clusters for FAM192A Gene

Family with sequence similarity 192, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM192A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14
SP1: - - - - -
SP2: - - - - -
SP3:
SP4: -
SP5: - -
SP6: -
SP7:

Relevant External Links for FAM192A Gene

GeneLoc Exon Structure for
FAM192A
ECgene alternative splicing isoforms for
FAM192A

Expression for FAM192A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM192A Gene

Protein differential expression in normal tissues from HIPED for FAM192A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (39.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM192A Gene



Protein tissue co-expression partners for FAM192A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM192A Gene:

FAM192A

SOURCE GeneReport for Unigene cluster for FAM192A Gene:

Hs.396740

Evidence on tissue expression from TISSUES for FAM192A Gene

  • Eye(4.3)
  • Intestine(4.3)
  • Lymph node(4.3)
  • Nervous system(4.3)
genes like me logo Genes that share expression patterns with FAM192A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM192A Gene

Orthologs for FAM192A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM192A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM192A 34 35
  • 99.48 (n)
cow
(Bos Taurus)
Mammalia NIP30 35
  • 96 (a)
OneToOne
FAM192A 34
  • 92.23 (n)
dog
(Canis familiaris)
Mammalia FAM192A 34 35
  • 91.6 (n)
rat
(Rattus norvegicus)
Mammalia Nip30 34
  • 88.8 (n)
mouse
(Mus musculus)
Mammalia Fam192a 34 16 35
  • 88.54 (n)
oppossum
(Monodelphis domestica)
Mammalia FAM192A 35
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM192A 35
  • 83 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM192A 34 35
  • 77.03 (n)
lizard
(Anolis carolinensis)
Reptilia FAM192A 35
  • 77 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam192a 34
  • 65.61 (n)
Str.11948 34
African clawed frog
(Xenopus laevis)
Amphibia nip30-prov 34
zebrafish
(Danio rerio)
Actinopterygii fam192a 34 35
  • 65.37 (n)
wufa02g12 34
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP010768 34
  • 52 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG14480 34 35
  • 49.35 (n)
worm
(Caenorhabditis elegans)
Secernentea C25A1.1 35
  • 37 (a)
OneToOne
Species where no ortholog for FAM192A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM192A Gene

ENSEMBL:
Gene Tree for FAM192A (if available)
TreeFam:
Gene Tree for FAM192A (if available)

Paralogs for FAM192A Gene

Pseudogenes.org Pseudogenes for FAM192A Gene

genes like me logo Genes that share paralogs with FAM192A: view

No data available for Paralogs for FAM192A Gene

Variants for FAM192A Gene

Sequence variations from dbSNP and Humsavar for FAM192A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000049834 -- 57,181,256(+) GATTG(C/T)ATTCA intron-variant
rs1000210351 -- 57,174,611(+) CTATC(C/T)TGATT intron-variant, upstream-variant-2KB
rs1000227907 -- 57,168,107(+) TGAAA(C/T)GTCTT intron-variant
rs1000256645 -- 57,186,918(+) ACGGT(C/G)TAGGT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000342220 -- 57,168,373(+) ATGGG(C/T)ACAAG intron-variant

Variation tolerance for FAM192A Gene

Residual Variation Intolerance Score: 35.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.36; 7.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM192A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM192A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM192A Gene

Disorders for FAM192A Gene

Relevant External Links for FAM192A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM192A

No disorders were found for FAM192A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM192A Gene

Publications for FAM192A Gene

  1. Isolation, expression analysis and characterization of NEFA-interacting nuclear protein 30 and RING finger and SPRY domain containing 1 in skeletal muscle. (PMID: 26497270) Waddell D.S. … Eldredge J.T. (Gene 2016) 2 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  5. Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. (PMID: 25609649) Li X. … Chen J. (Mol. Syst. Biol. 2015) 3 64

Products for FAM192A Gene

Sources for FAM192A Gene

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