FAM192A Gene
protein-coding GIFtS: 44
GCID: GC16M057187
|
|
family with sequence similarity 192, member A(Previous name: chromosome 16 open reading frame 94 )
(Previous symbol: C16orf94)
| |
Aliases
for FAM192A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 192, Member A1 2 | | Chromosome 16 Open Reading Frame 941 | | C16orf941 2 3 | | CDA0182 | | NIP301 2 3 | | Protein FAM192A2 | | NEFA-Interacting Nuclear Protein NIP302 3 | | |
Export aliases for FAM192A gene to outside databasesPrevious GC identifers: GC16M055744 GC16M043056 |
Summaries
for FAM192A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for FAM192A (NIP30)
|
Genomic Views
for FAM192A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM192A
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM192A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM192A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q13 Ensembl cytogenetic band: 16q13 HGNC cytogenetic band: 16q13FAM192A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M057187: view genomic region
(about GC identifiers)
Start:
|
57,186,378 bp from pter |
End:
|
57,220,028 bp from pter |
Size:
|
33,651 bases |
Orientation:
|
minus strand |
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Proteins
for FAM192A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F192A_HUMAN, Q9GZU8 (See
protein sequence)Recommended Name: Protein FAM192A Size: 254 amino acids; 28912 Da
Subcellular location: Nucleus (Potential)Explore the universe of human proteins at neXtProt for FAM192A: NX_Q9GZU8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9GZU8
FAM192A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_079222.1
ENSEMBL proteins: ENSP00000335808 ENSP00000455082 ENSP00000454901 ENSP00000457532 ENSP00000457740 ENSP00000457850 ENSP00000456211 ENSP00000454596 ENSP00000457695 ENSP00000455170 ENSP00000456931 ENSP00000457269 ENSP00000457185 ENSP00000455890 ENSP00000456673 ENSP00000454649 ENSP00000455299 ENSP00000455325 ENSP00000374098
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- |
FAM192A for ontologies About GeneDecksing
FAM192A Antibody Products:
Assay Products for FAM192A: |
Protein
Domains /
Families
for FAM192A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM192A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9GZU8ProtoNet protein and cluster: Q9GZU8 |
Function
for FAM192A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM192A (NM_024946) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM192A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM192A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM192A |
|
Pathways & Interactions
for FAM192A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM192A
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/9 Interacting proteins for FAM192A (Q9GZU83 ENSP000003358084) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
|
Drugs & Compounds
for FAM192A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM192A
Search CenterWatch for drugs/clinical trials and news about FAM192A / F192A
|
Transcripts
for FAM192A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM192A gene: NM_024946.2 Unigene Cluster for FAM192A: Family with sequence similarity 192, member A Hs.396740 [show with all ESTs]Unigene Representative Sequence: NM_02494618/21 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21): ENST00000309137(uc021tix.1 uc021tiy.1) ENST00000566403(uc021tja.1)
ENST00000565956 ENST00000566077 ENST00000569266(uc021tiz.1) ENST00000567439
ENST00000564108 ENST00000562324 ENST00000567044 ENST00000565458 ENST00000562406
ENST00000566584 ENST00000568671 ENST00000565760 ENST00000566481 ENST00000570184
ENST00000566681 ENST00000564424
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM192A (NM_024946) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM192A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM192A |
Additional cDNA sequence: AF212249.1 AF271785.1 AF356585.1 AK023291.1 AK025452.1 AL834421.1 BC020536.1 BC063409.1 BC071952.1 24/27 DOTS entries (see all 27): DT.100796608 DT.216475 DT.100796617 DT.100796612 DT.100030088 DT.97855357 DT.101965565 DT.100735547 DT.100796609 DT.120713500 DT.120713536 DT.100796615 DT.95366641 DT.100796620 DT.121246280 DT.92021554 DT.100796611 DT.40298215 DT.91856844 DT.91884283 DT.95165679 DT.100796614 DT.120713489 DT.91639619 24/411 AceView cDNA sequences (see all 411): BQ231824 BM810196 BF873583 AI819590 AI346704 BU737637 BE858277 CA308353 CB163443 Z38458 AI819378 BM829907 AI439636 AL834421 AI655644 BG289673 BF437300 AI418212 AI360945 BF797671 BQ636939 AI863261 BI962899 BM724406
GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FAM192A (see all 7) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM192A
|
Expression
for FAM192A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM192A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAGCTAATA
About this image
See FAM192A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM192A
SOURCE GeneReport for Unigene cluster: Hs.396740
SABiosciences Custom PCR Arrays for FAM192A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM192A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM192A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM192A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM192A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM192A |
Orthologs
for FAM192A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM192A gene from 9/25 species (see all 25) About this table
ENSEMBL Gene Tree for FAM192A (if available)
TreeFam Gene Tree for FAM192A (if available) |
Paralogs
for FAM192A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM192A gene
1 SIMAP similar gene for FAM192A using alignment to 14 protein entries: F192A_HUMAN (see all proteins):NIP30
FAM192A for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FAM192A
PGOHUM00000246103
|
Genomic Variants
for FAM192A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM192A (57186378 - 57220028 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM192A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM192A |
|
Disorders
/ Diseases
for FAM192A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM192A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM192A gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with FAM192A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Identification of novel ATP13A2 interactors and their role in a-synuclein misfolding and toxicity. (PubMed id 22645275)1 Usenovic M....Krainc D. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Comparative proteomic analysis identifies a role for S UMO in protein quality control. (PubMed id 21693764)1 Tatham M.H....Hay R.T. (2011)
- System-wide changes to SUMO modifications in response to heat shock. (PubMed id 19471022)1 Golebiowski F....Hay R.T. (2009)
|
External Searches for FAM192A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM192A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM192A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM192A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM192A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM192A gene:
Search GeneIP for patents involving FAM192A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM192A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM192A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM192A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM192A | | | OriGene Protein Over-expression Lysate for FAM192A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM192A | | OriGene 3'-UTR Clone for FAM192A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM192A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM192A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM192A | | OriGene Custom Protein Services for FAM192A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM192A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM192A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM192A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM192A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM192A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM192A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM192A |
| |  |  |  |  | | | | |
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 | | | FAM192A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM192A |
|  |  |  | | | | ThermoFisher Antibodies for FAM192A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM192A |
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