FAM188B2 Gene
protein-coding GIFtS: 27
GCID: GC03M150588 (predicted)
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family with sequence similarity 188, member B2(Previous name: chromosome 3 open reading frame 76 )
(Previous symbol: C3orf76)
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Aliases
for FAM188B2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 188, Member B21 2 | | C3orf761 2 3 | | Chromosome 3 Open Reading Frame 761 | | CLRN12 | | Putative UPF0526 Protein B2 |
Export aliases for FAM188B2 gene to outside databasesPrevious GC identifers: GC03M152073 GC03M147962 |
Summaries
for FAM188B2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM188B2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NT_005612.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM188B2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM188B2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM188B2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q25.1 Ensembl cytogenetic band: 3q25.1 HGNC cytogenetic band: 3q25.1FAM188B2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M150588: view genomic region
(about GC identifiers)
Start:
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150,588,832 bp from pter |
End:
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150,621,044 bp from pter |
Size:
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32,213 bases |
Orientation:
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minus strand |
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Proteins
for FAM188B2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F1882_HUMAN, A8MYZ0 (See
protein sequence)Recommended Name: Protein FAM188B2 Size: 360 amino acids; 41070 DaExplore the universe of human proteins at neXtProt for FAM188B2: NX_A8MYZ0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A8MYZ0
FAM188B2 Protein expression data from MOPED and PaxDb: --
ENSEMBL proteins: ENSP00000454934 ENSP00000454591
Human Recombinant Protein Products:
FAM188B2 Antibody Products:
Assay Products for FAM188B2: |
Protein
Domains /
Families
for FAM188B2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
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FAM188B2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A8MYZ0ProtoNet protein and cluster: A8MYZ0 UniProtKB/Swiss-Prot: F1882_HUMAN, A8MYZ0Similarity: Belongs to the FAM188 family |
Function
for FAM188B2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM188B2 |
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Pathways & Interactions
for FAM188B2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM188B2
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Drugs & Compounds
for FAM188B2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM188B2
Search CenterWatch for drugs/clinical trials and news about FAM188B2 / F1882 
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Transcripts
for FAM188B2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for FAM188B2: Family with sequence similarity 188, member B2 Hs.736436 [show with all ESTs]Unigene Representative Sequence: HM6261392 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000465419 ENST00000397891
Additional cDNA sequence: HM626139.1 1 DOTS entry: DT.120920318
GeneLoc Exon Structure
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Expression
for FAM188B2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM188B2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
SOURCE GeneReport for Unigene cluster: Hs.736436
SABiosciences Custom PCR Arrays for FAM188B2
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM188B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM188B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM188B2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM188B2 |
Orthologs
for FAM188B2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for FAM188B2 gene from 4/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM188B26 |
Uncharacterized protein |
64(a) |
1 ↔ 1 |
9(25183062-25185676) |
lizard
(Anolis carolinensis) |
Reptilia |
FAM188B26 |
-- |
63(a) |
1 ↔ 1 |
3(18208757-18220694) |
zebrafish
(Danio rerio) |
Actinopterygii |
CABZ01085857.16 |
-- |
58(a) |
1 ↔ 1 |
15(3791777-3802203) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG141426 |
-- |
24(a) |
1 ↔ 1 |
3L(11166614-11169992) |
ENSEMBL Gene Tree for FAM188B2 (if available)
TreeFam Gene Tree for FAM188B2 (if available) |
Paralogs
for FAM188B2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM188B2 gene
- FAM188B2 FAM188A2
FAM188B2 for paralogs About GeneDecksing
|
Genomic Variants
for FAM188B2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for FAM188B2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM188B2 for disorders About MalaCards
FAM188B2 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: FAM188B2 (1 document)
Export disorders for FAM188B2 gene to outside databases
|
Publications
for FAM188B2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM188B2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM188B2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)1, 2 Muzny D.M....Gibbs R.A. (2006)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Alternative splice variants of the USH3A gene Clarin 1 (CLRN1). (PubMed id 20717163)1 Vastinsalo H.... Sankila E.M. (2010)
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External Searches for FAM188B2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM188B2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing FAM188B2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM188B2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM188B2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM188B2 gene:
Search GeneIP for patents involving FAM188B2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM188B2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM188B2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM188B2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM188B2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM188B2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM188B2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM188B2 |
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 | | | FAM188B2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM188B2 |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM188B2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM188B2 |
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