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Aliases for FAM188B2 Gene

Aliases for FAM188B2 Gene

  • Family With Sequence Similarity 188 Member B2 2 3
  • Family With Sequence Similarity 188, Member B2 2 3
  • C3orf76 3 4
  • Chromosome 3 Open Reading Frame 76 2
  • Putative UPF0526 Protein B 3
  • RP11-166N6.1 5
  • CLRN1 3

External Ids for FAM188B2 Gene

Previous HGNC Symbols for FAM188B2 Gene

  • C3orf76

Previous GeneCards Identifiers for FAM188B2 Gene

  • GC03M152073
  • GC03M150588
  • GC03M147962

Summaries for FAM188B2 Gene

GeneCards Summary for FAM188B2 Gene

FAM188B2 (Family With Sequence Similarity 188 Member B2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM188B2 Gene

Genomics for FAM188B2 Gene

Regulatory Elements for FAM188B2 Gene

Promoters for FAM188B2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM188B2 on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM188B2 Gene

150,871,045 bp from pter
150,891,060 bp from pter
20,016 bases
Minus strand

Genomic View for FAM188B2 Gene

Genes around FAM188B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM188B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM188B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for FAM188B2 Gene

Proteins for FAM188B2 Gene

  • Protein details for FAM188B2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM188B2
    Protein Accession:

    Protein attributes for FAM188B2 Gene

    360 amino acids
    Molecular mass:
    41070 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM188B2 Gene

Proteomics data for FAM188B2 Gene at MOPED

Post-translational modifications for FAM188B2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM188B2 Gene

Domains & Families for FAM188B2 Gene

Protein Domains for FAM188B2 Gene


Suggested Antigen Peptide Sequences for FAM188B2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



F1882_HUMAN :
  • Belongs to the FAM188 family.
  • Belongs to the FAM188 family.
genes like me logo Genes that share domains with FAM188B2: view

No data available for Gene Families for FAM188B2 Gene

Function for FAM188B2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM188B2 Gene

Localization for FAM188B2 Gene

Subcellular locations from

Jensen Localization Image for FAM188B2 Gene COMPARTMENTS Subcellular localization image for FAM188B2 gene
Compartment Confidence
mitochondrion 2
cytosol 1
golgi apparatus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM188B2 Gene

Pathways & Interactions for FAM188B2 Gene

SuperPathways for FAM188B2 Gene

No Data Available

Interacting Proteins for FAM188B2 Gene

Gene Ontology (GO) - Biological Process for FAM188B2 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM188B2 Gene

Drugs & Compounds for FAM188B2 Gene

No Compound Related Data Available

Transcripts for FAM188B2 Gene

mRNA/cDNA for FAM188B2 Gene

(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM188B2 Gene

Family with sequence similarity 188, member B2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM188B2 Gene

No ASD Table

Relevant External Links for FAM188B2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM188B2 Gene

mRNA expression in normal human tissues for FAM188B2 Gene

mRNA differential expression in normal tissues according to GTEx for FAM188B2 Gene

This gene is overexpressed in Brain - Nucleus accumbens (basal ganglia) (x17.2), Brain - Caudate (basal ganglia) (x12.2), and Brain - Putamen (basal ganglia) (x8.8).

Protein differential expression in normal tissues from HIPED for FAM188B2 Gene

This gene is overexpressed in Blymphocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM188B2 Gene

SOURCE GeneReport for Unigene cluster for FAM188B2 Gene Hs.380222

genes like me logo Genes that share expression patterns with FAM188B2: view

Protein tissue co-expression partners for FAM188B2 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM188B2 Gene

Orthologs for FAM188B2 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM188B2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM188B2 36
  • 79 (a)
(Canis familiaris)
Mammalia FAM188B2 36
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
(Gallus gallus)
Aves FAM188B2 36
  • 64 (a)
(Anolis carolinensis)
Reptilia FAM188B2 36
  • 63 (a)
(Danio rerio)
Actinopterygii FAM188B2 36
  • 58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14142 36
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for FAM188B2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM188B2 Gene

Gene Tree for FAM188B2 (if available)
Gene Tree for FAM188B2 (if available)

Paralogs for FAM188B2 Gene

No data available for Paralogs for FAM188B2 Gene

Variants for FAM188B2 Gene

Variation tolerance for FAM188B2 Gene

Gene Damage Index Score: 1.70; 32.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM188B2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for FAM188B2 Gene

Disorders for FAM188B2 Gene

Relevant External Links for FAM188B2

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM188B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM188B2 Gene

Publications for FAM188B2 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Alternative splice variants of the USH3A gene Clarin 1 (CLRN1). (PMID: 20717163) Vastinsalo H. … Sankila E.M. (Eur. J. Hum. Genet. 2011) 3
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 3

Products for FAM188B2 Gene

Sources for FAM188B2 Gene

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