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Aliases for FAM187B Gene

Aliases for FAM187B Gene

  • Family With Sequence Similarity 187 Member B 2 3 5
  • Transmembrane Protein 162 2 3 4
  • Family With Sequence Similarity 187, Member B 2 3
  • TMEM162 3 4

External Ids for FAM187B Gene

Previous HGNC Symbols for FAM187B Gene

  • TMEM162

Previous GeneCards Identifiers for FAM187B Gene

  • GC19M040409
  • GC19M035715
  • GC19M032224
  • GC19M035225
  • GC19M035837

Summaries for FAM187B Gene

GeneCards Summary for FAM187B Gene

FAM187B (Family With Sequence Similarity 187 Member B) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM187B Gene

Genomics for FAM187B Gene

Regulatory Elements for FAM187B Gene

Enhancers for FAM187B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM187B on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM187B Gene

35,224,800 bp from pter
35,228,729 bp from pter
3,930 bases
Minus strand

Genomic View for FAM187B Gene

Genes around FAM187B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM187B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM187B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM187B Gene

Proteins for FAM187B Gene

  • Protein details for FAM187B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM187B
    Protein Accession:
    Secondary Accessions:
    • Q8N7G6

    Protein attributes for FAM187B Gene

    369 amino acids
    Molecular mass:
    42387 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM187B Gene

Proteomics data for FAM187B Gene at MOPED

Post-translational modifications for FAM187B Gene

  • Glycosylation at Asn 45, Asn 68, and Asn 130
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM187B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM187B Gene

Domains & Families for FAM187B Gene

Protein Domains for FAM187B Gene


Suggested Antigen Peptide Sequences for FAM187B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM187 family.
  • Belongs to the FAM187 family.
genes like me logo Genes that share domains with FAM187B: view

No data available for Gene Families for FAM187B Gene

Function for FAM187B Gene

genes like me logo Genes that share phenotypes with FAM187B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM187B Gene

Localization for FAM187B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM187B Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for FAM187B Gene COMPARTMENTS Subcellular localization image for FAM187B gene
Compartment Confidence
extracellular 2
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for FAM187B Gene

Pathways & Interactions for FAM187B Gene

SuperPathways for FAM187B Gene

No Data Available

Interacting Proteins for FAM187B Gene

Gene Ontology (GO) - Biological Process for FAM187B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM187B Gene

Drugs & Compounds for FAM187B Gene

No Compound Related Data Available

Transcripts for FAM187B Gene

mRNA/cDNA for FAM187B Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM187B Gene

Family with sequence similarity 187, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM187B Gene

No ASD Table

Relevant External Links for FAM187B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM187B Gene

mRNA expression in normal human tissues for FAM187B Gene

mRNA differential expression in normal tissues according to GTEx for FAM187B Gene

This gene is overexpressed in Testis (x50.1).

SOURCE GeneReport for Unigene cluster for FAM187B Gene Hs.128069

genes like me logo Genes that share expression patterns with FAM187B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM187B Gene

Orthologs for FAM187B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM187B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM187B 35
  • 70.7 (n)
  • 57.18 (a)
FAM187B 36
  • 56 (a)
(Canis familiaris)
Mammalia FAM187B 35
  • 76.48 (n)
  • 63.14 (a)
FAM187B 36
  • 57 (a)
(Pan troglodytes)
Mammalia FAM187B 35
  • 97.2 (n)
  • 94.58 (a)
FAM187B 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Fam187b 35
  • 65.19 (n)
  • 50.83 (a)
(Monodelphis domestica)
Mammalia FAM187B 36
  • 26 (a)
(Mus musculus)
Mammalia Fam187b 36
  • 49 (a)
(Anolis carolinensis)
Reptilia FAM187B 36
  • 26 (a)
Species with no ortholog for FAM187B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM187B Gene

Gene Tree for FAM187B (if available)
Gene Tree for FAM187B (if available)

Paralogs for FAM187B Gene Pseudogenes for FAM187B Gene

genes like me logo Genes that share paralogs with FAM187B: view

No data available for Paralogs for FAM187B Gene

Variants for FAM187B Gene

Sequence variations from dbSNP and Humsavar for FAM187B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs34873156 - 35,228,674(+) CATGG(A/G)TGGCA reference, missense
rs565791 - 35,228,203(+) TTTAC(A/G)CTCGC reference, missense
rs564117 - 35,228,035(+) AATGA(C/T)GTAAT reference, missense
rs8099919 -- 35,228,425(+) GGGCA(A/G)TGGAT reference, synonymous-codon
rs13382163 -- 35,228,036(+) ATGAC(A/C/G)TAATC reference, synonymous-codon, stop-gained

Structural Variations from Database of Genomic Variants (DGV) for FAM187B Gene

Variant ID Type Subtype PubMed ID
nsv510765 CNV Loss 20534489
dgv1080e1 CNV Complex 17122850

Variation tolerance for FAM187B Gene

Residual Variation Intolerance Score: 94.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 13.93; 95.96% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM187B Gene

Disorders for FAM187B Gene

Relevant External Links for FAM187B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM187B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM187B Gene

Publications for FAM187B Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM187B Gene

Sources for FAM187B Gene