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Aliases for FAM187B Gene

Aliases for FAM187B Gene

  • Family With Sequence Similarity 187, Member B 2 3
  • Transmembrane Protein 162 2 3 4
  • TMEM162 3 4
  • Protein FAM187B 3

External Ids for FAM187B Gene

Previous Symbols for FAM187B Gene

  • TMEM162

Summaries for FAM187B Gene

GeneCards Summary for FAM187B Gene

FAM187B (Family With Sequence Similarity 187, Member B) is a Protein Coding gene. An important paralog of this gene is FAM187A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM187B Gene

Genomics for FAM187B Gene

Genomic Location for FAM187B Gene

Start:
35,224,800 bp from pter
End:
35,228,729 bp from pter
Size:
3,930 bases
Orientation:
Minus strand

Genomic View for FAM187B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM187B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM187B Gene

Regulatory Elements for FAM187B Gene

Proteins for FAM187B Gene

  • Protein details for FAM187B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q17R55-F187B_HUMAN
    Recommended name:
    Protein FAM187B
    Protein Accession:
    Q17R55
    Secondary Accessions:
    • Q8N7G6

    Protein attributes for FAM187B Gene

    Size:
    369 amino acids
    Molecular mass:
    42387 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM187B Gene

Proteomics data for FAM187B Gene at MOPED

Post-translational modifications for FAM187B Gene

  • Glycosylation at Asn45, Asn68, and Asn130

Other Protein References for FAM187B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM187B Gene

Domains for FAM187B Gene

Protein Domains for FAM187B Gene

ProtoNet:

UniProtKB/Swiss-Prot:

F187B_HUMAN
Family:
  • Belongs to the FAM187 family.:
    • Q17R55
genes like me logo Genes that share domains with FAM187B: view

No data available for Gene Families for FAM187B Gene

Function for FAM187B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM187B Gene

Localization for FAM187B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM187B Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM187B Gene COMPARTMENTS Subcellular localization image for FAM187B gene
Compartment Confidence
extracellular 2
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM187B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM187B: view

Pathways for FAM187B Gene

SuperPathways for FAM187B Gene

No Data Available

Interacting Proteins for FAM187B Gene

Gene Ontology (GO) - Biological Process for FAM187B Gene

None

No data available for Pathways by source for FAM187B Gene

Transcripts for FAM187B Gene

mRNA/cDNA for FAM187B Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(12) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM187B Gene

Family with sequence similarity 187, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM187B Gene

No ASD Table

Relevant External Links for FAM187B Gene

GeneLoc Exon Structure for
FAM187B
ECgene alternative splicing isoforms for
FAM187B

Expression for FAM187B Gene

mRNA expression in normal human tissues for FAM187B Gene

mRNA differential expression in normal tissues according to GTEx for FAM187B Gene

This gene is overexpressed in Testis (50.1).

SOURCE GeneReport for Unigene cluster for FAM187B Gene Hs.128069

genes like me logo Genes that share expressions with FAM187B: view

Orthologs for FAM187B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM187B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM187B 36
  • 97.2 (n)
  • 94.58 (a)
FAM187B 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM187B 36
  • 70.7 (n)
  • 57.18 (a)
FAM187B 37
  • 56 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM187B 36
  • 76.48 (n)
  • 63.14 (a)
FAM187B 37
  • 57 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam187b 16
Fam187b 37
  • 49 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM187B 37
  • 26 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam187b 36
  • 65.19 (n)
  • 50.83 (a)
lizard
(Anolis carolinensis)
Reptilia FAM187B 37
  • 26 (a)
OneToOne
Species with no ortholog for FAM187B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM187B Gene

ENSEMBL:
Gene Tree for FAM187B (if available)
TreeFam:
Gene Tree for FAM187B (if available)

Paralogs for FAM187B Gene

Paralogs for FAM187B Gene

Pseudogenes.org Pseudogenes for FAM187B Gene

genes like me logo Genes that share paralogs with FAM187B: view

Variants for FAM187B Gene

Sequence variations from dbSNP and Humsavar for FAM187B Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs504389 -- 35,229,873(-) TTGAA(G/T)ATGTA upstream-variant-2KB
rs507251 -- 35,229,556(-) cctga(C/G)tagct upstream-variant-2KB
rs528717 -- 35,229,825(+) tgcac(A/G)tgctg upstream-variant-2KB
rs531922 -- 35,226,789(+) TGGCC(A/G)GGGGC intron-variant
rs532458 -- 35,230,240(+) aaata(A/C)ataaa upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM187B Gene

Variant ID Type Subtype PubMed ID
nsv510765 CNV Loss 20534489
dgv1080e1 CNV Complex 17122850

Relevant External Links for FAM187B Gene

HapMap Linkage Disequilibrium report
FAM187B

Disorders for FAM187B Gene

Relevant External Links for FAM187B

Genetic Association Database (GAD)
FAM187B
genes like me logo Genes that share disorders with FAM187B: view

No data available for UniProtKB/Swiss-Prot for FAM187B Gene

Publications for FAM187B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM187B Gene

Sources for FAM187B Gene

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