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Aliases for FAM187A Gene

Aliases for FAM187A Gene

  • Family With Sequence Similarity 187 Member A 2 3 5
  • Family With Sequence Similarity 187, Member A 2

External Ids for FAM187A Gene

Previous GeneCards Identifiers for FAM187A Gene

  • GC00U922894
  • GC17P042979

Summaries for FAM187A Gene

GeneCards Summary for FAM187A Gene

FAM187A (Family With Sequence Similarity 187 Member A) is a Protein Coding gene. GO annotations related to this gene include protein homodimerization activity. An important paralog of this gene is CCDC103.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM187A Gene

Genomics for FAM187A Gene

Regulatory Elements for FAM187A Gene

Enhancers for FAM187A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F044898 0.2 ENCODE 17 +0.6 599 4.1 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 EFTUD2 GJC1 FAM187A HEXIM1 ASB16-AS1 ENSG00000224505 PIR50226
GH17F044904 0.9 Ensembl ENCODE 16.2 +6.6 6564 3.0 HDAC1 ATF1 ZEB1 GATA2 SCRT2 RCOR1 FOS CREM SMARCC1 ZBTB2 EFTUD2 FAM187A GC17P044905 GC17P044908 PIR49404
GH17F044827 0.2 ENCODE 13.7 -69.8 -69808 3.9 SIN3A GLI4 ZNF2 ETS1 GLIS2 KLF7 SP3 REST TSHZ1 ZNF623 FAM187A GC17M044778 GJC1
GH17F044822 0.7 ENCODE 13.6 -76.7 -76731 1.5 ATF1 MLX DMAP1 ZNF48 YY1 ZNF121 PAF1 SP5 PPARG KAT8 FAM187A HIGD1B ENSG00000224911 GFAP C1QL1 MEIOC CCDC43 GC17M044778 PIR52410
GH17F044842 0.5 Ensembl ENCODE 12.9 -56.2 -56166 3.1 ATF1 MLX ZFP64 ARID4B SLC30A9 SP5 MXD4 PPARG KAT8 NFIL3 EFTUD2 FAM187A ENSG00000224911 GFAP C1QL1 MEIOC ENSG00000267505 HIGD1B GJC1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around FAM187A on UCSC Golden Path with GeneCards custom track

Promoters for FAM187A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM187A Gene

44,899,712 bp from pter
44,905,390 bp from pter
5,679 bases
Plus strand

Genomic View for FAM187A Gene

Genes around FAM187A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM187A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM187A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for FAM187A Gene

Proteins for FAM187A Gene

  • Protein details for FAM187A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ig-like V-type domain-containing protein FAM187A
    Protein Accession:

    Protein attributes for FAM187A Gene

    413 amino acids
    Molecular mass:
    47349 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM187A Gene

Post-translational modifications for FAM187A Gene

No Post-translational modifications

Other Protein References for FAM187A Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for FAM187A Gene

Domains & Families for FAM187A Gene

Gene Families for FAM187A Gene

Protein Domains for FAM187A Gene

Suggested Antigen Peptide Sequences for FAM187A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Belongs to the FAM187 family.
  • Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Belongs to the FAM187 family.
genes like me logo Genes that share domains with FAM187A: view

Function for FAM187A Gene

Animal Model Products

miRNA for FAM187A Gene

miRTarBase miRNAs that target FAM187A

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM187A Gene

Localization for FAM187A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM187A Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for FAM187A Gene COMPARTMENTS Subcellular localization image for FAM187A gene
Compartment Confidence
cytosol 2

Gene Ontology (GO) - Cellular Components for FAM187A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM187A: view

Pathways & Interactions for FAM187A Gene

SuperPathways for FAM187A Gene

No Data Available

Interacting Proteins for FAM187A Gene

Gene Ontology (GO) - Biological Process for FAM187A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM187A Gene

Transcripts for FAM187A Gene

mRNA/cDNA for FAM187A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM187A Gene

No ASD Table

Relevant External Links for FAM187A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM187A Gene

mRNA expression in normal human tissues for FAM187A Gene

mRNA expression in normal human tissues for FAM187A Gene

Protein differential expression in normal tissues from HIPED for FAM187A Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM187A Gene

Protein tissue co-expression partners for FAM187A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM187A Gene:

genes like me logo Genes that share expression patterns with FAM187A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM187A Gene

Orthologs for FAM187A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM187A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM187A 35
  • 97 (a)
(Bos Taurus)
Mammalia FAM187A 35
  • 84 (a)
(Canis familiaris)
Mammalia FAM187A 35
  • 84 (a)
(Mus musculus)
Mammalia Fam187a 35
  • 78 (a)
(Monodelphis domestica)
Mammalia FAM187A 35
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia FAM187A 35
  • 67 (a)
(Gallus gallus)
Aves FAM187A 35
  • 54 (a)
(Anolis carolinensis)
Reptilia FAM187A 35
  • 56 (a)
Species where no ortholog for FAM187A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM187A Gene

Gene Tree for FAM187A (if available)
Gene Tree for FAM187A (if available)

Paralogs for FAM187A Gene

Paralogs for FAM187A Gene

genes like me logo Genes that share paralogs with FAM187A: view

Variants for FAM187A Gene

Variation tolerance for FAM187A Gene

Gene Damage Index Score: 10.08; 90.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM187A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for FAM187A Gene

Disorders for FAM187A Gene

Relevant External Links for FAM187A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM187A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM187A Gene

Publications for FAM187A Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for FAM187A Gene

Sources for FAM187A Gene

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